{"id":"https://openalex.org/W2979699424","doi":"https://doi.org/10.1093/bioinformatics/btz768","title":"Expectation pooling: an effective and interpretable pooling method for predicting DNA\u2013protein binding","display_name":"Expectation pooling: an effective and interpretable pooling method for predicting DNA\u2013protein binding","publication_year":2019,"publication_date":"2019-10-08","ids":{"openalex":"https://openalex.org/W2979699424","doi":"https://doi.org/10.1093/bioinformatics/btz768","mag":"2979699424","pmid":"https://pubmed.ncbi.nlm.nih.gov/31598637"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btz768","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz768","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/5/1405/32793985/btz768.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/36/5/1405/32793985/btz768.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100426938","display_name":"Xiao Luo","orcid":"https://orcid.org/0000-0002-7987-3714"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiao Luo","raw_affiliation_strings":["School of Mathematical Sciences"],"affiliations":[{"raw_affiliation_string":"School of Mathematical Sciences","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082692993","display_name":"Xinming Tu","orcid":"https://orcid.org/0009-0004-0833-6876"},"institutions":[{"id":"https://openalex.org/I4391767842","display_name":"State Key Laboratory of Protein and Plant Gene Research","ror":"https://ror.org/05xbqrp21","country_code":null,"type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I4391767842"]},{"id":"https://openalex.org/I139025015","display_name":"Pioneer (United States)","ror":"https://ror.org/05jke7315","country_code":"US","type":"company","lineage":["https://openalex.org/I139025015","https://openalex.org/I4210104019"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xinming Tu","raw_affiliation_strings":["Biomedical Pioneering Innovation Center (BIOPIC), Beijing Advanced Innovation Center for Genomics (ICG), Center for Bioinformatics (CBI), and the State Key Laboratory of Protein and Plant Gene Research at School of Life Sciences"],"affiliations":[{"raw_affiliation_string":"Biomedical Pioneering Innovation Center (BIOPIC), Beijing Advanced Innovation Center for Genomics (ICG), Center for Bioinformatics (CBI), and the State Key Laboratory of Protein and Plant Gene Research at School of Life Sciences","institution_ids":["https://openalex.org/I139025015","https://openalex.org/I4391767842"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055926977","display_name":"Yang Ding","orcid":"https://orcid.org/0000-0001-8530-7981"},"institutions":[{"id":"https://openalex.org/I4391767842","display_name":"State Key Laboratory of Protein and Plant Gene Research","ror":"https://ror.org/05xbqrp21","country_code":null,"type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I4391767842"]},{"id":"https://openalex.org/I139025015","display_name":"Pioneer (United States)","ror":"https://ror.org/05jke7315","country_code":"US","type":"company","lineage":["https://openalex.org/I139025015","https://openalex.org/I4210104019"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yang Ding","raw_affiliation_strings":["Biomedical Pioneering Innovation Center (BIOPIC), Beijing Advanced Innovation Center for Genomics (ICG), Center for Bioinformatics (CBI), and the State Key Laboratory of Protein and Plant Gene Research at School of Life Sciences"],"affiliations":[{"raw_affiliation_string":"Biomedical Pioneering Innovation Center (BIOPIC), Beijing Advanced Innovation Center for Genomics (ICG), Center for Bioinformatics (CBI), and the State Key Laboratory of Protein and Plant Gene Research at School of Life Sciences","institution_ids":["https://openalex.org/I139025015","https://openalex.org/I4391767842"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048549975","display_name":"Ge Gao","orcid":"https://orcid.org/0000-0001-6470-8815"},"institutions":[{"id":"https://openalex.org/I139025015","display_name":"Pioneer (United States)","ror":"https://ror.org/05jke7315","country_code":"US","type":"company","lineage":["https://openalex.org/I139025015","https://openalex.org/I4210104019"]},{"id":"https://openalex.org/I4391767842","display_name":"State Key Laboratory of Protein and Plant Gene Research","ror":"https://ror.org/05xbqrp21","country_code":null,"type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I4391767842"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ge Gao","raw_affiliation_strings":["Biomedical Pioneering Innovation Center (BIOPIC), Beijing Advanced Innovation Center for Genomics (ICG), Center for Bioinformatics (CBI), and the State Key Laboratory of Protein and Plant Gene Research at School of Life Sciences"],"affiliations":[{"raw_affiliation_string":"Biomedical Pioneering Innovation Center (BIOPIC), Beijing Advanced Innovation Center for Genomics (ICG), Center for Bioinformatics (CBI), and the State Key Laboratory of Protein and Plant Gene Research at School of Life Sciences","institution_ids":["https://openalex.org/I139025015","https://openalex.org/I4391767842"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091013880","display_name":"Minghua Deng","orcid":"https://orcid.org/0000-0002-9143-1898"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Minghua Deng","raw_affiliation_strings":["Center for Quantitative Biology, Peking University , Beijing 100871, China","School of Mathematical Sciences"],"affiliations":[{"raw_affiliation_string":"Center for Quantitative Biology, Peking University , Beijing 100871, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"School of Mathematical Sciences","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5048549975","https://openalex.org/A5091013880"],"corresponding_institution_ids":["https://openalex.org/I139025015","https://openalex.org/I20231570","https://openalex.org/I4391767842"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":1.7048,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.84919678,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"36","issue":"5","first_page":"1405","last_page":"1412"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pooling","display_name":"Pooling","score":0.9348218441009521},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7102341651916504},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6388071179389954},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.627631425857544},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.6198155879974365},{"id":"https://openalex.org/keywords/probabilistic-logic","display_name":"Probabilistic logic","score":0.6148051023483276},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.5615381598472595},{"id":"https://openalex.org/keywords/hyperparameter","display_name":"Hyperparameter","score":0.5244091749191284},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.42644405364990234},{"id":"https://openalex.org/keywords/statistical-model","display_name":"Statistical model","score":0.4212897717952728},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.39975422620773315}],"concepts":[{"id":"https://openalex.org/C70437156","wikidata":"https://www.wikidata.org/wiki/Q7228652","display_name":"Pooling","level":2,"score":0.9348218441009521},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7102341651916504},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6388071179389954},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.627631425857544},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.6198155879974365},{"id":"https://openalex.org/C49937458","wikidata":"https://www.wikidata.org/wiki/Q2599292","display_name":"Probabilistic logic","level":2,"score":0.6148051023483276},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.5615381598472595},{"id":"https://openalex.org/C8642999","wikidata":"https://www.wikidata.org/wiki/Q4171168","display_name":"Hyperparameter","level":2,"score":0.5244091749191284},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.42644405364990234},{"id":"https://openalex.org/C114289077","wikidata":"https://www.wikidata.org/wiki/Q3284399","display_name":"Statistical model","level":2,"score":0.4212897717952728},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.39975422620773315},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009042","descriptor_name":"Motivation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009042","descriptor_name":"Motivation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009042","descriptor_name":"Motivation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009042","descriptor_name":"Motivation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btz768","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz768","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/5/1405/32793985/btz768.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31598637","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31598637","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:7703793","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7703793","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btz768","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz768","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/5/1405/32793985/btz768.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4218223795","display_name":null,"funder_award_id":"2016YFC0901603","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G5690750078","display_name":null,"funder_award_id":"31871342","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2979699424.pdf","grobid_xml":"https://content.openalex.org/works/W2979699424.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W370143576","https://openalex.org/W1019830208","https://openalex.org/W1480376833","https://openalex.org/W1521843029","https://openalex.org/W1976526581","https://openalex.org/W1988393300","https://openalex.org/W2028904582","https://openalex.org/W2048869777","https://openalex.org/W2049633694","https://openalex.org/W2095705004","https://openalex.org/W2103777723","https://openalex.org/W2109255472","https://openalex.org/W2112796928","https://openalex.org/W2117951582","https://openalex.org/W2135046866","https://openalex.org/W2145091349","https://openalex.org/W2149769193","https://openalex.org/W2154579312","https://openalex.org/W2171808845","https://openalex.org/W2198606573","https://openalex.org/W2299467264","https://openalex.org/W2433743436","https://openalex.org/W2526468814","https://openalex.org/W2528491735","https://openalex.org/W2546302380","https://openalex.org/W2560674852","https://openalex.org/W2594559005","https://openalex.org/W2751343946","https://openalex.org/W2799487719","https://openalex.org/W2809442901","https://openalex.org/W2898283559","https://openalex.org/W2901218091","https://openalex.org/W2930309796","https://openalex.org/W2951748044","https://openalex.org/W2963919294","https://openalex.org/W2990138404","https://openalex.org/W4236965008","https://openalex.org/W4301409532","https://openalex.org/W6674330103","https://openalex.org/W6682751323","https://openalex.org/W6688902765","https://openalex.org/W6760655233"],"related_works":["https://openalex.org/W2953234277","https://openalex.org/W2626256601","https://openalex.org/W147410782","https://openalex.org/W4390421286","https://openalex.org/W2900413183","https://openalex.org/W4280563792","https://openalex.org/W4206951940","https://openalex.org/W4401096132","https://openalex.org/W4382602594","https://openalex.org/W4387850423"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2}],"updated_date":"2025-11-23T05:10:03.516525","created_date":"2025-10-10T00:00:00"}