{"id":"https://openalex.org/W2957922973","doi":"https://doi.org/10.1093/bioinformatics/btz378","title":"Inheritance and variability of kinetic gene expression parameters in microbial cells: modeling and inference from lineage tree data","display_name":"Inheritance and variability of kinetic gene expression parameters in microbial cells: modeling and inference from lineage tree data","publication_year":2019,"publication_date":"2019-05-09","ids":{"openalex":"https://openalex.org/W2957922973","doi":"https://doi.org/10.1093/bioinformatics/btz378","mag":"2957922973","pmid":"https://pubmed.ncbi.nlm.nih.gov/31510690"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btz378","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz378","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/14/i586/28913747/btz378.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/35/14/i586/28913747/btz378.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019196076","display_name":"Aline Marguet","orcid":"https://orcid.org/0000-0002-8294-9695"},"institutions":[{"id":"https://openalex.org/I4210101348","display_name":"Centre Inria de l'Universit\u00e9 Grenoble Alpes","ror":"https://ror.org/00n8d6z93","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1326498283","https://openalex.org/I4210101348"]},{"id":"https://openalex.org/I899635006","display_name":"Universit\u00e9 Grenoble Alpes","ror":"https://ror.org/02rx3b187","country_code":"FR","type":"education","lineage":["https://openalex.org/I899635006"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Aline Marguet","raw_affiliation_strings":["Univ. Grenoble Alpes, Inria, Grenoble, France","Modeling, simulation, measurement, and control of bacterial regulatory networks"],"affiliations":[{"raw_affiliation_string":"Univ. Grenoble Alpes, Inria, Grenoble, France","institution_ids":["https://openalex.org/I899635006","https://openalex.org/I4210101348"]},{"raw_affiliation_string":"Modeling, simulation, measurement, and control of bacterial regulatory networks","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086297713","display_name":"Marc Lavielle","orcid":"https://orcid.org/0000-0003-2680-6339"},"institutions":[{"id":"https://openalex.org/I142476485","display_name":"\u00c9cole Polytechnique","ror":"https://ror.org/05hy3tk52","country_code":"FR","type":"education","lineage":["https://openalex.org/I142476485","https://openalex.org/I4210145102"]},{"id":"https://openalex.org/I4210126360","display_name":"Inria Saclay - \u00cele de France","ror":"https://ror.org/0315e5x55","country_code":"FR","type":"government","lineage":["https://openalex.org/I1326498283","https://openalex.org/I4210126360"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marc Lavielle","raw_affiliation_strings":["Inria Saclay & Ecole Polytechnique, Palaiseau, France"],"affiliations":[{"raw_affiliation_string":"Inria Saclay & Ecole Polytechnique, Palaiseau, France","institution_ids":["https://openalex.org/I4210126360","https://openalex.org/I142476485"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010375183","display_name":"Eugenio Cinquemani","orcid":"https://orcid.org/0000-0003-3353-6525"},"institutions":[{"id":"https://openalex.org/I4210101348","display_name":"Centre Inria de l'Universit\u00e9 Grenoble Alpes","ror":"https://ror.org/00n8d6z93","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1326498283","https://openalex.org/I4210101348"]},{"id":"https://openalex.org/I899635006","display_name":"Universit\u00e9 Grenoble Alpes","ror":"https://ror.org/02rx3b187","country_code":"FR","type":"education","lineage":["https://openalex.org/I899635006"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Eugenio Cinquemani","raw_affiliation_strings":["Univ. Grenoble Alpes, Inria, Grenoble, France","Modeling, simulation, measurement, and control of bacterial regulatory networks"],"affiliations":[{"raw_affiliation_string":"Univ. Grenoble Alpes, Inria, Grenoble, France","institution_ids":["https://openalex.org/I899635006","https://openalex.org/I4210101348"]},{"raw_affiliation_string":"Modeling, simulation, measurement, and control of bacterial regulatory networks","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5010375183"],"corresponding_institution_ids":["https://openalex.org/I4210101348","https://openalex.org/I899635006"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":0.7729,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.71085016,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"35","issue":"14","first_page":"i586","last_page":"i595"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9968000054359436,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5857390761375427},{"id":"https://openalex.org/keywords/inheritance","display_name":"Inheritance (genetic algorithm)","score":0.5575568675994873},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.5247535705566406},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4856661558151245},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.47283467650413513},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.4657367765903473},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.4251338839530945},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.42485982179641724},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.341880738735199},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.11972865462303162}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5857390761375427},{"id":"https://openalex.org/C2780902518","wikidata":"https://www.wikidata.org/wiki/Q6033780","display_name":"Inheritance (genetic algorithm)","level":3,"score":0.5575568675994873},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5247535705566406},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4856661558151245},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.47283467650413513},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4657367765903473},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.4251338839530945},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.42485982179641724},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.341880738735199},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.11972865462303162},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btz378","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz378","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/14/i586/28913747/btz378.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31510690","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31510690","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:HAL:hal-02317115v1","is_oa":true,"landing_page_url":"https://hal.science/hal-02317115","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics, 2019, 35 (14), pp.i586-i595. ⟨10.1093/bioinformatics/btz378⟩","raw_type":"Journal articles"},{"id":"pmh:oai:europepmc.org:5588693","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6612834","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btz378","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz378","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/14/i586/28913747/btz378.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G8907879167","display_name":null,"funder_award_id":"ANR-16-CE33-0018","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"}],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2957922973.pdf","grobid_xml":"https://content.openalex.org/works/W2957922973.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W178056938","https://openalex.org/W1596437242","https://openalex.org/W1965324089","https://openalex.org/W1966062610","https://openalex.org/W1974475129","https://openalex.org/W1982396530","https://openalex.org/W1986206712","https://openalex.org/W2055742299","https://openalex.org/W2058221907","https://openalex.org/W2081970839","https://openalex.org/W2105512180","https://openalex.org/W2114870653","https://openalex.org/W2120575449","https://openalex.org/W2121793131","https://openalex.org/W2122121413","https://openalex.org/W2137088684","https://openalex.org/W2138163236","https://openalex.org/W2145246556","https://openalex.org/W2157851226","https://openalex.org/W2163427867","https://openalex.org/W2164343005","https://openalex.org/W2202141609","https://openalex.org/W2262285937","https://openalex.org/W2550226555","https://openalex.org/W2550701680","https://openalex.org/W2609276452","https://openalex.org/W2770907192","https://openalex.org/W2782185136","https://openalex.org/W2794281325","https://openalex.org/W2898780494","https://openalex.org/W2949890765","https://openalex.org/W2950115754","https://openalex.org/W3104620767","https://openalex.org/W6684104292","https://openalex.org/W6729551437"],"related_works":["https://openalex.org/W2386928530","https://openalex.org/W2912461320","https://openalex.org/W4210442184","https://openalex.org/W2921828092","https://openalex.org/W2373906875","https://openalex.org/W2903457525","https://openalex.org/W3032874291","https://openalex.org/W2005057264","https://openalex.org/W2363156284","https://openalex.org/W2415025170"],"abstract_inverted_index":{"Supplementary":[0],"material":[1],"is":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":5},{"year":2018,"cited_by_count":1}],"updated_date":"2026-04-09T08:11:56.329763","created_date":"2025-10-10T00:00:00"}