{"id":"https://openalex.org/W2955754489","doi":"https://doi.org/10.1093/bioinformatics/btz372","title":"PRECISE: a domain adaptation approach to transfer predictors of drug response from pre-clinical models to tumors","display_name":"PRECISE: a domain adaptation approach to transfer predictors of drug response from pre-clinical models to tumors","publication_year":2019,"publication_date":"2019-05-09","ids":{"openalex":"https://openalex.org/W2955754489","doi":"https://doi.org/10.1093/bioinformatics/btz372","mag":"2955754489","pmid":"https://pubmed.ncbi.nlm.nih.gov/31510654"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btz372","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz372","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/14/i510/28913240/btz372.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/35/14/i510/28913240/btz372.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056948757","display_name":"Soufiane Mourragui","orcid":"https://orcid.org/0000-0001-6920-2696"},"institutions":[{"id":"https://openalex.org/I2898336195","display_name":"The Netherlands Cancer Institute","ror":"https://ror.org/03xqtf034","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2898336195"]},{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]},{"id":"https://openalex.org/I4210111138","display_name":"Oncode Institute","ror":"https://ror.org/01n92vv28","country_code":"NL","type":"education","lineage":["https://openalex.org/I4210111138"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Soufiane Mourragui","raw_affiliation_strings":["Computational Cancer Biology, Division of Molecular Carcinogenesis, Oncode Institute, the Netherlands Cancer Institute, Amsterdam CX, The Netherlands","Department of Intelligent Systems, Faculty of EEMCS, Delft University of Technology, Delft CD, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Computational Cancer Biology, Division of Molecular Carcinogenesis, Oncode Institute, the Netherlands Cancer Institute, Amsterdam CX, The Netherlands","institution_ids":["https://openalex.org/I4210111138","https://openalex.org/I2898336195"]},{"raw_affiliation_string":"Department of Intelligent Systems, Faculty of EEMCS, Delft University of Technology, Delft CD, The Netherlands","institution_ids":["https://openalex.org/I98358874"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086060106","display_name":"Marco Loog","orcid":"https://orcid.org/0000-0002-1298-8461"},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]}],"countries":["DK","NL"],"is_corresponding":false,"raw_author_name":"Marco Loog","raw_affiliation_strings":["Department of Computer Science, University of Copenhagen, Copenhagen, Denmark","Department of Intelligent Systems, Faculty of EEMCS, Delft University of Technology, Delft CD, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Copenhagen, Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"Department of Intelligent Systems, Faculty of EEMCS, Delft University of Technology, Delft CD, The Netherlands","institution_ids":["https://openalex.org/I98358874"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036462844","display_name":"Mark A. van de Wiel","orcid":"https://orcid.org/0000-0003-4780-8472"},"institutions":[{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"funder","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4210134973","display_name":"MRC Biostatistics Unit","ror":"https://ror.org/046vje122","country_code":"GB","type":"facility","lineage":["https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I4210134973","https://openalex.org/I90344618"]}],"countries":["GB","NL"],"is_corresponding":false,"raw_author_name":"Mark A van de Wiel","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Amsterdam University Medical Centers, Amsterdam, The Netherlands","MRC Biostatistics Unit, University of Cambridge, Cambridge, UK"],"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Amsterdam University Medical Centers, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210151833"]},{"raw_affiliation_string":"MRC Biostatistics Unit, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I4210134973","https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052699801","display_name":"Marcel Reinders","orcid":"https://orcid.org/0000-0002-1148-1562"},"institutions":[{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]},{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Marcel J T Reinders","raw_affiliation_strings":["Computational Biology Center, Leiden University Medical Center, Leiden ZC, The Netherlands","Department of Intelligent Systems, Faculty of EEMCS, Delft University of Technology, Delft CD, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Computational Biology Center, Leiden University Medical Center, Leiden ZC, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]},{"raw_affiliation_string":"Department of Intelligent Systems, Faculty of EEMCS, Delft University of Technology, Delft CD, The Netherlands","institution_ids":["https://openalex.org/I98358874"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020129085","display_name":"Lodewyk F.A. Wessels","orcid":"https://orcid.org/0000-0002-1656-6995"},"institutions":[{"id":"https://openalex.org/I2898336195","display_name":"The Netherlands Cancer Institute","ror":"https://ror.org/03xqtf034","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2898336195"]},{"id":"https://openalex.org/I4210111138","display_name":"Oncode Institute","ror":"https://ror.org/01n92vv28","country_code":"NL","type":"education","lineage":["https://openalex.org/I4210111138"]},{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Lodewyk F A Wessels","raw_affiliation_strings":["Computational Cancer Biology, Division of Molecular Carcinogenesis, Oncode Institute, the Netherlands Cancer Institute, Amsterdam CX, The Netherlands","Department of Intelligent Systems, Faculty of EEMCS, Delft University of Technology, Delft CD, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Computational Cancer Biology, Division of Molecular Carcinogenesis, Oncode Institute, the Netherlands Cancer Institute, Amsterdam CX, The Netherlands","institution_ids":["https://openalex.org/I4210111138","https://openalex.org/I2898336195"]},{"raw_affiliation_string":"Department of Intelligent Systems, Faculty of EEMCS, Delft University of Technology, Delft CD, The Netherlands","institution_ids":["https://openalex.org/I98358874"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5020129085"],"corresponding_institution_ids":["https://openalex.org/I2898336195","https://openalex.org/I4210111138","https://openalex.org/I98358874"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":7.9983,"has_fulltext":true,"cited_by_count":83,"citation_normalized_percentile":{"value":0.97873126,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"35","issue":"14","first_page":"i510","last_page":"i519"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.992900013923645,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drug-response","display_name":"Drug response","score":0.5882778167724609},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5103248953819275},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.36802634596824646},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.3483878970146179},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.33798515796661377},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2749943137168884}],"concepts":[{"id":"https://openalex.org/C2994119904","wikidata":"https://www.wikidata.org/wiki/Q1251001","display_name":"Drug response","level":3,"score":0.5882778167724609},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5103248953819275},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.36802634596824646},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.3483878970146179},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.33798515796661377},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2749943137168884},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001686","descriptor_name":"Biological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001686","descriptor_name":"Biological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001686","descriptor_name":"Biological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005544","descriptor_name":"Forecasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005544","descriptor_name":"Forecasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005544","descriptor_name":"Forecasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1093/bioinformatics/btz372","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz372","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/14/i510/28913240/btz372.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31510654","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31510654","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:tudelft.nl:uuid:2408b812-028b-4c1b-90ca-44b97a5b027f","is_oa":true,"landing_page_url":"http://resolver.tudelft.nl/uuid:2408b812-028b-4c1b-90ca-44b97a5b027f","pdf_url":"http://resolver.tudelft.nl/uuid:2408b812-028b-4c1b-90ca-44b97a5b027f","source":{"id":"https://openalex.org/S4306400906","display_name":"Research Repository (Delft University of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I98358874","host_organization_name":"Delft University of Technology","host_organization_lineage":["https://openalex.org/I98358874"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"journal article"},{"id":"pmh:oai:europepmc.org:5588750","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6612899","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/3e50859e-9749-465f-9ade-f9c1ba1ded5d","is_oa":false,"landing_page_url":"http://www.scopus.com/inward/record.url?scp=85068898672&partnerID=8YFLogxK","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":""},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/3e50859e-9749-465f-9ade-f9c1ba1ded5d","is_oa":true,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/3e50859e-9749-465f-9ade-f9c1ba1ded5d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Mourragui , S , Loog , M , Van De Wiel , M A , Reinders , M J T & Wessels , L F A 2019 , ' PRECISE : A domain adaptation approach to transfer predictors of drug response from pre-clinical models to tumors ' , Bioinformatics , vol. 35 , no. 14 , btz372 , pp. i510-i519 . https://doi.org/10.1093/bioinformatics/btz372","raw_type":"article"},{"id":"pmh:vumc:oai:pure.atira.dk:publications/dd6b5a5e-ce2d-4ecf-ae95-294fa5f48a8f","is_oa":true,"landing_page_url":"https://research.vumc.nl/en/publications/dd6b5a5e-ce2d-4ecf-ae95-294fa5f48a8f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics, 35(14):btz372, i510 - i519. Oxford University Press","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btz372","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz372","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/14/i510/28913240/btz372.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5799999833106995}],"awards":[{"id":"https://openalex.org/G3504454571","display_name":null,"funder_award_id":"00812","funder_id":"https://openalex.org/F4320321007","funder_display_name":"ZonMw"},{"id":"https://openalex.org/G631628569","display_name":null,"funder_award_id":"40-00812-98-16012","funder_id":"https://openalex.org/F4320321007","funder_display_name":"ZonMw"}],"funders":[{"id":"https://openalex.org/F4320321007","display_name":"ZonMw","ror":"https://ror.org/01yaj9a77"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2955754489.pdf","grobid_xml":"https://content.openalex.org/works/W2955754489.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W19078547","https://openalex.org/W2018663224","https://openalex.org/W2101234009","https://openalex.org/W2114843025","https://openalex.org/W2115403315","https://openalex.org/W2120149881","https://openalex.org/W2122825543","https://openalex.org/W2130410032","https://openalex.org/W2137570937","https://openalex.org/W2139132031","https://openalex.org/W2165698076","https://openalex.org/W2168102484","https://openalex.org/W2461427403","https://openalex.org/W2737053924","https://openalex.org/W2747036018","https://openalex.org/W2756073160","https://openalex.org/W2756202949","https://openalex.org/W2765689414","https://openalex.org/W2798909945","https://openalex.org/W2808845633","https://openalex.org/W2886855629","https://openalex.org/W2899866452","https://openalex.org/W2901139514","https://openalex.org/W2950998564","https://openalex.org/W2997591727","https://openalex.org/W4321000873","https://openalex.org/W6600744685","https://openalex.org/W6675354045"],"related_works":["https://openalex.org/W2961085424","https://openalex.org/W4306674287","https://openalex.org/W4387369504","https://openalex.org/W4394896187","https://openalex.org/W3170094116","https://openalex.org/W4386462264","https://openalex.org/W3107602296","https://openalex.org/W4364306694","https://openalex.org/W4312192474","https://openalex.org/W4283697347"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":3}],"updated_date":"2026-04-13T07:58:08.660418","created_date":"2025-10-10T00:00:00"}