{"id":"https://openalex.org/W2921359953","doi":"https://doi.org/10.1093/bioinformatics/btz166","title":"GREP: genome for REPositioning drugs","display_name":"GREP: genome for REPositioning drugs","publication_year":2019,"publication_date":"2019-03-09","ids":{"openalex":"https://openalex.org/W2921359953","doi":"https://doi.org/10.1093/bioinformatics/btz166","mag":"2921359953","pmid":"https://pubmed.ncbi.nlm.nih.gov/30859178"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btz166","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz166","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/19/3821/48976061/bioinformatics_35_19_3821.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/35/19/3821/48976061/bioinformatics_35_19_3821.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064515889","display_name":"Saori Sakaue","orcid":"https://orcid.org/0000-0003-3618-9717"},"institutions":[{"id":"https://openalex.org/I4210150921","display_name":"RIKEN Center for Integrative Medical Sciences","ror":"https://ror.org/04mb6s476","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652","https://openalex.org/I4210150921"]},{"id":"https://openalex.org/I98285908","display_name":"Osaka University","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Saori Sakaue","raw_affiliation_strings":["Department of Allergy and Rheumatology, Graduate School of Medicine, the University of Tokyo , Tokyo, Japan","Department of Statistical Genetics, Osaka University Graduate School of Medicine , Suita, Japan","Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences , Yokohama, Japan"],"affiliations":[{"raw_affiliation_string":"Department of Allergy and Rheumatology, Graduate School of Medicine, the University of Tokyo , Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]},{"raw_affiliation_string":"Department of Statistical Genetics, Osaka University Graduate School of Medicine , Suita, Japan","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences , Yokohama, Japan","institution_ids":["https://openalex.org/I4210150921"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037133689","display_name":"Yukinori Okada","orcid":"https://orcid.org/0000-0002-0311-8472"},"institutions":[{"id":"https://openalex.org/I4210150921","display_name":"RIKEN Center for Integrative Medical Sciences","ror":"https://ror.org/04mb6s476","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652","https://openalex.org/I4210150921"]},{"id":"https://openalex.org/I98285908","display_name":"Osaka University","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Yukinori Okada","raw_affiliation_strings":["Department of Statistical Genetics, Osaka University Graduate School of Medicine , Suita, Japan","Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences , Yokohama, Japan","Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University , Suita, Japan"],"affiliations":[{"raw_affiliation_string":"Department of Statistical Genetics, Osaka University Graduate School of Medicine , Suita, Japan","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences , Yokohama, Japan","institution_ids":["https://openalex.org/I4210150921"]},{"raw_affiliation_string":"Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University , Suita, Japan","institution_ids":["https://openalex.org/I98285908"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5037133689"],"corresponding_institution_ids":["https://openalex.org/I4210150921","https://openalex.org/I98285908"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":2.1471,"has_fulltext":true,"cited_by_count":75,"citation_normalized_percentile":{"value":0.87971314,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"35","issue":"19","first_page":"3821","last_page":"3823"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9846000075340271,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/python","display_name":"Python (programming language)","score":0.7202971577644348},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5610644817352295},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.54183429479599},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.5416446924209595},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.5371153354644775},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.5222495198249817},{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"Genome-wide association study","score":0.5172489285469055},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5008344650268555},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4697318971157074},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.44572532176971436},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3282099664211273},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3166900873184204},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.1125248372554779},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.10076430439949036}],"concepts":[{"id":"https://openalex.org/C519991488","wikidata":"https://www.wikidata.org/wiki/Q28865","display_name":"Python (programming language)","level":2,"score":0.7202971577644348},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5610644817352295},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.54183429479599},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.5416446924209595},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.5371153354644775},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.5222495198249817},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.5172489285469055},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5008344650268555},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4697318971157074},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.44572532176971436},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3282099664211273},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3166900873184204},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.1125248372554779},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.10076430439949036},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btz166","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz166","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/19/3821/48976061/bioinformatics_35_19_3821.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:30859178","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30859178","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:europepmc.org:5733245","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6761931","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btz166","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz166","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/19/3821/48976061/bioinformatics_35_19_3821.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1158798147","display_name":null,"funder_award_id":"16gm6010001h0001","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"},{"id":"https://openalex.org/G1160716697","display_name":null,"funder_award_id":"KAKENHI [","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G1420648410","display_name":"\u770c\u6c11\u6027\u3068\u5730\u57df\u6027\u306e\u7814\u7a76(\u7d992\u5e74)","funder_award_id":"10001","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G3284062447","display_name":null,"funder_award_id":"16gm6010001h0001","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G3379022032","display_name":"\u8fb2\u696d\u69cb\u9020\u6539\u5584\u306b\u4f34\u306a\u3046\u5730\u57df\u6559\u80b2\u518d\u7de8\u6210\u306b\u95a2\u3059\u308b\u7814\u7a76-\u5730\u57df\u985e\u578b\u3068\u6559\u80b2\u8a08\u753b-(\u7d992\u5e74)","funder_award_id":"10041","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G3980822508","display_name":"\u6771\u6d77\u5730\u65b9\u306b\u304a\u3051\u308b\u7523\u696d\u69cb\u9020\u304a\u3088\u3073\u793e\u4f1a\u69cb\u9020\u306e\u5909\u5bb9\u306b\u304b\u3093\u3059\u308b\u7814\u7a76","funder_award_id":"041004","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G4381687251","display_name":null,"funder_award_id":"h0001","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"},{"id":"https://openalex.org/G4657425800","display_name":null,"funder_award_id":"15H05","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G5256887504","display_name":null,"funder_award_id":"Japan Society for the Promotion of Science (JSPS)","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6308906652","display_name":null,"funder_award_id":"15H05911","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7752643416","display_name":null,"funder_award_id":"Japan","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7929773644","display_name":null,"funder_award_id":"17ek0410041h0001","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"},{"id":"https://openalex.org/G8185458848","display_name":null,"funder_award_id":"17ek0410041h0001","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G975188225","display_name":null,"funder_award_id":"KAKENHI","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"},{"id":"https://openalex.org/G987146328","display_name":"\u6cb3\u53e3\u6e56\u306e\u6c34\u53ce\u652f","funder_award_id":"410041","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320311405","display_name":"Japan Agency for Medical Research and Development","ror":"https://ror.org/004rtk039"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2921359953.pdf","grobid_xml":"https://content.openalex.org/works/W2921359953.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W1544009106","https://openalex.org/W1989590412","https://openalex.org/W2050086663","https://openalex.org/W2116868464","https://openalex.org/W2118822739","https://openalex.org/W2557530941","https://openalex.org/W2558715006","https://openalex.org/W2761275051","https://openalex.org/W2767891136","https://openalex.org/W2787229753","https://openalex.org/W2791863121","https://openalex.org/W2799517867","https://openalex.org/W2953357410"],"related_works":["https://openalex.org/W2341492732","https://openalex.org/W3187193180","https://openalex.org/W106542691","https://openalex.org/W1699080303","https://openalex.org/W4297799326","https://openalex.org/W3116064965","https://openalex.org/W4287027380","https://openalex.org/W3193760048","https://openalex.org/W4285822516","https://openalex.org/W2789551765"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":22},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":6}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}