{"id":"https://openalex.org/W2900285507","doi":"https://doi.org/10.1093/bioinformatics/bty938","title":"Pan-genomic analysis provides novel insights into the association of <i>E.coli</i> with human host and its minimal genome","display_name":"Pan-genomic analysis provides novel insights into the association of <i>E.coli</i> with human host and its minimal genome","publication_year":2018,"publication_date":"2018-11-08","ids":{"openalex":"https://openalex.org/W2900285507","doi":"https://doi.org/10.1093/bioinformatics/bty938","mag":"2900285507","pmid":"https://pubmed.ncbi.nlm.nih.gov/30418478"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/bty938","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bty938","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107220026","display_name":"Zhikai Yang","orcid":"https://orcid.org/0000-0001-6104-5083"},"institutions":[{"id":"https://openalex.org/I4210151209","display_name":"Collaborative Innovation Center of Chemical Science and Engineering Tianjin","ror":"https://ror.org/0225a5s12","country_code":"CN","type":"facility","lineage":["https://openalex.org/I162868743","https://openalex.org/I205237279","https://openalex.org/I4210151209"]},{"id":"https://openalex.org/I2801663168","display_name":"Chinese National Human Genome Center","ror":"https://ror.org/01wq93z70","country_code":"CN","type":"facility","lineage":["https://openalex.org/I2801663168"]},{"id":"https://openalex.org/I162868743","display_name":"Tianjin University","ror":"https://ror.org/012tb2g32","country_code":"CN","type":"education","lineage":["https://openalex.org/I162868743"]},{"id":"https://openalex.org/I4210129994","display_name":"SinoGenoMax (China)","ror":"https://ror.org/02xfgyt86","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210129994"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhi-Kai Yang","raw_affiliation_strings":["Department of Physics, School of Science","Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, China","SinoGenoMax Co., Ltd./Chinese National Human Genome Center, Beijing, China","SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, China"],"affiliations":[{"raw_affiliation_string":"Department of Physics, School of Science","institution_ids":[]},{"raw_affiliation_string":"Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, China","institution_ids":["https://openalex.org/I162868743"]},{"raw_affiliation_string":"SinoGenoMax Co., Ltd./Chinese National Human Genome Center, Beijing, China","institution_ids":["https://openalex.org/I2801663168","https://openalex.org/I4210129994"]},{"raw_affiliation_string":"SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, China","institution_ids":["https://openalex.org/I4210151209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009471000","display_name":"Hao Luo","orcid":"https://orcid.org/0000-0003-2714-8817"},"institutions":[{"id":"https://openalex.org/I162868743","display_name":"Tianjin University","ror":"https://ror.org/012tb2g32","country_code":"CN","type":"education","lineage":["https://openalex.org/I162868743"]},{"id":"https://openalex.org/I4210151209","display_name":"Collaborative Innovation Center of Chemical Science and Engineering Tianjin","ror":"https://ror.org/0225a5s12","country_code":"CN","type":"facility","lineage":["https://openalex.org/I162868743","https://openalex.org/I205237279","https://openalex.org/I4210151209"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao Luo","raw_affiliation_strings":["Department of Physics, School of Science","Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, China","SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, China"],"affiliations":[{"raw_affiliation_string":"Department of Physics, School of Science","institution_ids":[]},{"raw_affiliation_string":"Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, China","institution_ids":["https://openalex.org/I162868743"]},{"raw_affiliation_string":"SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, China","institution_ids":["https://openalex.org/I4210151209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100604295","display_name":"Yanming Zhang","orcid":"https://orcid.org/0009-0009-6192-581X"},"institutions":[{"id":"https://openalex.org/I4210129994","display_name":"SinoGenoMax (China)","ror":"https://ror.org/02xfgyt86","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210129994"]},{"id":"https://openalex.org/I2801663168","display_name":"Chinese National Human Genome Center","ror":"https://ror.org/01wq93z70","country_code":"CN","type":"facility","lineage":["https://openalex.org/I2801663168"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanming Zhang","raw_affiliation_strings":["SinoGenoMax Co., Ltd./Chinese National Human Genome Center, Beijing, China"],"affiliations":[{"raw_affiliation_string":"SinoGenoMax Co., Ltd./Chinese National Human Genome Center, Beijing, China","institution_ids":["https://openalex.org/I2801663168","https://openalex.org/I4210129994"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086747207","display_name":"Baijing Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I2801663168","display_name":"Chinese National Human Genome Center","ror":"https://ror.org/01wq93z70","country_code":"CN","type":"facility","lineage":["https://openalex.org/I2801663168"]},{"id":"https://openalex.org/I4210129994","display_name":"SinoGenoMax (China)","ror":"https://ror.org/02xfgyt86","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210129994"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Baijing Wang","raw_affiliation_strings":["SinoGenoMax Co., Ltd./Chinese National Human Genome Center, Beijing, China"],"affiliations":[{"raw_affiliation_string":"SinoGenoMax Co., Ltd./Chinese National Human Genome Center, Beijing, China","institution_ids":["https://openalex.org/I2801663168","https://openalex.org/I4210129994"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074242312","display_name":"Feng Gao","orcid":"https://orcid.org/0000-0002-9563-3841"},"institutions":[{"id":"https://openalex.org/I162868743","display_name":"Tianjin University","ror":"https://ror.org/012tb2g32","country_code":"CN","type":"education","lineage":["https://openalex.org/I162868743"]},{"id":"https://openalex.org/I4210151209","display_name":"Collaborative Innovation Center of Chemical Science and Engineering Tianjin","ror":"https://ror.org/0225a5s12","country_code":"CN","type":"facility","lineage":["https://openalex.org/I162868743","https://openalex.org/I205237279","https://openalex.org/I4210151209"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Feng Gao","raw_affiliation_strings":["Department of Physics, School of Science","Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, China","SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, China"],"affiliations":[{"raw_affiliation_string":"Department of Physics, School of Science","institution_ids":[]},{"raw_affiliation_string":"Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, China","institution_ids":["https://openalex.org/I162868743"]},{"raw_affiliation_string":"SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, China","institution_ids":["https://openalex.org/I4210151209"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5074242312"],"corresponding_institution_ids":["https://openalex.org/I162868743","https://openalex.org/I4210151209"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":1.306,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.80684998,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"35","issue":"12","first_page":"1987","last_page":"1991"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.8157618045806885},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.7063142657279968},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.6148949861526489},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.5901625156402588},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.4771120846271515},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.45028454065322876},{"id":"https://openalex.org/keywords/phylogenetic-tree","display_name":"Phylogenetic tree","score":0.4466816186904907},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4434420168399811},{"id":"https://openalex.org/keywords/host-adaptation","display_name":"Host adaptation","score":0.4376469850540161}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8157618045806885},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.7063142657279968},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6148949861526489},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5901625156402588},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4771120846271515},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.45028454065322876},{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.4466816186904907},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4434420168399811},{"id":"https://openalex.org/C2776914050","wikidata":"https://www.wikidata.org/wiki/Q19597524","display_name":"Host adaptation","level":4,"score":0.4376469850540161},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/bty938","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bty938","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:30418478","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30418478","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G202076348","display_name":null,"funder_award_id":"91746119","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7243257119","display_name":null,"funder_award_id":"21621004","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8573908226","display_name":null,"funder_award_id":"31171238","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G999540423","display_name":null,"funder_award_id":"31571358","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1519765314","https://openalex.org/W1932877617","https://openalex.org/W1973658950","https://openalex.org/W1982579644","https://openalex.org/W2008856488","https://openalex.org/W2010698369","https://openalex.org/W2096093282","https://openalex.org/W2108385415","https://openalex.org/W2111107538","https://openalex.org/W2111967267","https://openalex.org/W2119025443","https://openalex.org/W2122673596","https://openalex.org/W2127641304","https://openalex.org/W2146538795","https://openalex.org/W2159916488","https://openalex.org/W2167084464","https://openalex.org/W2219314901","https://openalex.org/W2304674135","https://openalex.org/W2463118776","https://openalex.org/W2499767775","https://openalex.org/W2602439962","https://openalex.org/W2603382765","https://openalex.org/W2609834193","https://openalex.org/W2769091450","https://openalex.org/W2770252239","https://openalex.org/W2807938045"],"related_works":["https://openalex.org/W2360987025","https://openalex.org/W2387178301","https://openalex.org/W3144733943","https://openalex.org/W2785993273","https://openalex.org/W2382269147","https://openalex.org/W2799462113","https://openalex.org/W3184323118","https://openalex.org/W36834100","https://openalex.org/W2376819606","https://openalex.org/W1935994699"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":6}],"updated_date":"2026-03-04T09:10:02.777135","created_date":"2018-11-16T00:00:00"}