{"id":"https://openalex.org/W2952263670","doi":"https://doi.org/10.1093/bioinformatics/bty767","title":"Methods for automatic reference trees and multilevel phylogenetic placement","display_name":"Methods for automatic reference trees and multilevel phylogenetic placement","publication_year":2018,"publication_date":"2018-08-30","ids":{"openalex":"https://openalex.org/W2952263670","doi":"https://doi.org/10.1093/bioinformatics/bty767","mag":"2952263670","pmid":"https://pubmed.ncbi.nlm.nih.gov/30169747"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/bty767","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bty767","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/7/1151/48967648/bioinformatics_35_7_1151.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/35/7/1151/48967648/bioinformatics_35_7_1151.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005887668","display_name":"Lucas Czech","orcid":"https://orcid.org/0000-0002-1340-9644"},"institutions":[{"id":"https://openalex.org/I71030271","display_name":"Heidelberg Institute for Theoretical Studies","ror":"https://ror.org/01f7bcy98","country_code":"DE","type":"facility","lineage":["https://openalex.org/I71030271"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Lucas Czech","raw_affiliation_strings":["Scientific Computing Group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany"],"raw_orcid":"https://orcid.org/0000-0002-1340-9644","affiliations":[{"raw_affiliation_string":"Scientific Computing Group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany","institution_ids":["https://openalex.org/I71030271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087735622","display_name":"Pierre Barbera","orcid":"https://orcid.org/0000-0002-3437-150X"},"institutions":[{"id":"https://openalex.org/I71030271","display_name":"Heidelberg Institute for Theoretical Studies","ror":"https://ror.org/01f7bcy98","country_code":"DE","type":"facility","lineage":["https://openalex.org/I71030271"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Pierre Barbera","raw_affiliation_strings":["Scientific Computing Group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany"],"raw_orcid":"https://orcid.org/0000-0002-3437-150X","affiliations":[{"raw_affiliation_string":"Scientific Computing Group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany","institution_ids":["https://openalex.org/I71030271"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025640090","display_name":"Alexandros Stamatakis","orcid":"https://orcid.org/0000-0003-0353-0691"},"institutions":[{"id":"https://openalex.org/I102335020","display_name":"Karlsruhe Institute of Technology","ror":"https://ror.org/04t3en479","country_code":"DE","type":"education","lineage":["https://openalex.org/I102335020","https://openalex.org/I1305996414"]},{"id":"https://openalex.org/I71030271","display_name":"Heidelberg Institute for Theoretical Studies","ror":"https://ror.org/01f7bcy98","country_code":"DE","type":"facility","lineage":["https://openalex.org/I71030271"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alexandros Stamatakis","raw_affiliation_strings":["Institute for Theoretical Informatics, Karlsruhe Institute of Technology, Karlsruhe, Germany","Scientific Computing Group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Theoretical Informatics, Karlsruhe Institute of Technology, Karlsruhe, Germany","institution_ids":["https://openalex.org/I102335020"]},{"raw_affiliation_string":"Scientific Computing Group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany","institution_ids":["https://openalex.org/I71030271"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5005887668"],"corresponding_institution_ids":["https://openalex.org/I71030271"],"apc_list":{"value":3989,"currency":"USD","value_usd":3989},"apc_paid":{"value":3989,"currency":"USD","value_usd":3989},"fwci":2.1505,"has_fulltext":true,"cited_by_count":45,"citation_normalized_percentile":{"value":0.88729941,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"35","issue":"7","first_page":"1151","last_page":"1158"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9458000063896179,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9458000063896179,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11986","display_name":"Scientific Computing and Data Management","score":0.01940000057220459,"subfield":{"id":"https://openalex.org/subfields/1802","display_name":"Information Systems and Management"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T13664","display_name":"Genome Rearrangement Algorithms","score":0.00839999970048666,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6611769795417786},{"id":"https://openalex.org/keywords/phylogenetic-tree","display_name":"Phylogenetic tree","score":0.656076192855835},{"id":"https://openalex.org/keywords/preprocessor","display_name":"Preprocessor","score":0.5168376564979553},{"id":"https://openalex.org/keywords/workflow","display_name":"Workflow","score":0.5070760250091553},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.5006372928619385},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.43253710865974426},{"id":"https://openalex.org/keywords/construct","display_name":"Construct (python library)","score":0.43118977546691895},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4274137616157532},{"id":"https://openalex.org/keywords/phylogenetics","display_name":"Phylogenetics","score":0.42324337363243103},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.29574334621429443},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.25884637236595154},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.1760166883468628}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6611769795417786},{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.656076192855835},{"id":"https://openalex.org/C34736171","wikidata":"https://www.wikidata.org/wiki/Q918333","display_name":"Preprocessor","level":2,"score":0.5168376564979553},{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.5070760250091553},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.5006372928619385},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.43253710865974426},{"id":"https://openalex.org/C2780801425","wikidata":"https://www.wikidata.org/wiki/Q5164392","display_name":"Construct (python library)","level":2,"score":0.43118977546691895},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4274137616157532},{"id":"https://openalex.org/C90132467","wikidata":"https://www.wikidata.org/wiki/Q171184","display_name":"Phylogenetics","level":3,"score":0.42324337363243103},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.29574334621429443},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25884637236595154},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.1760166883468628},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D054892","descriptor_name":"Metagenome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054892","descriptor_name":"Metagenome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054892","descriptor_name":"Metagenome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057188","descriptor_name":"Workflow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057188","descriptor_name":"Workflow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057188","descriptor_name":"Workflow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/bty767","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bty767","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/7/1151/48967648/bioinformatics_35_7_1151.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:30169747","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30169747","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5438746","is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6449752","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6449752","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6449752","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/bty767","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bty767","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/7/1151/48967648/bioinformatics_35_7_1151.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Decent work and economic growth","score":0.5600000023841858,"id":"https://metadata.un.org/sdg/8"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320324316","display_name":"Klaus Tschira Stiftung","ror":"https://ror.org/052jep661"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2952263670.pdf","grobid_xml":"https://content.openalex.org/works/W2952263670.grobid-xml"},"referenced_works_count":52,"referenced_works":["https://openalex.org/W1510306455","https://openalex.org/W1881066983","https://openalex.org/W1988925586","https://openalex.org/W2007447692","https://openalex.org/W2022111190","https://openalex.org/W2033900229","https://openalex.org/W2034285706","https://openalex.org/W2034706898","https://openalex.org/W2037320822","https://openalex.org/W2061177996","https://openalex.org/W2067658227","https://openalex.org/W2067752346","https://openalex.org/W2068187483","https://openalex.org/W2087076382","https://openalex.org/W2089649677","https://openalex.org/W2099747733","https://openalex.org/W2103296919","https://openalex.org/W2109982529","https://openalex.org/W2124141867","https://openalex.org/W2124927293","https://openalex.org/W2125230147","https://openalex.org/W2128769815","https://openalex.org/W2129626961","https://openalex.org/W2131415145","https://openalex.org/W2145840889","https://openalex.org/W2151350595","https://openalex.org/W2151831732","https://openalex.org/W2154071138","https://openalex.org/W2157553803","https://openalex.org/W2159008215","https://openalex.org/W2170024099","https://openalex.org/W2229420368","https://openalex.org/W2313349352","https://openalex.org/W2319824271","https://openalex.org/W2327081444","https://openalex.org/W2603078022","https://openalex.org/W2603346833","https://openalex.org/W2766358903","https://openalex.org/W2773939681","https://openalex.org/W2792312485","https://openalex.org/W2795360781","https://openalex.org/W2808461744","https://openalex.org/W2857901319","https://openalex.org/W2889019390","https://openalex.org/W2950912511","https://openalex.org/W2951358594","https://openalex.org/W4300566050","https://openalex.org/W6658825153","https://openalex.org/W6659922009","https://openalex.org/W6749010161","https://openalex.org/W6749970427","https://openalex.org/W6752424609"],"related_works":["https://openalex.org/W2174809885","https://openalex.org/W2883025420","https://openalex.org/W2057191541","https://openalex.org/W2949296710","https://openalex.org/W1992658754","https://openalex.org/W2111939425","https://openalex.org/W2065083790","https://openalex.org/W2604174992","https://openalex.org/W2375383082","https://openalex.org/W1974895455"],"abstract_inverted_index":{"MOTIVATION:":[0],"In":[1],"most":[2],"metagenomic":[3],"sequencing":[4],"studies,":[5],"the":[6,13,17,29,57,75,80,92,100,156],"initial":[7],"analysis":[8],"step":[9],"consists":[10],"in":[11,79],"assessing":[12],"evolutionary":[14,30],"provenance":[15],"of":[16,32,52,77],"sequences.":[18],"Phylogenetic":[19],"(or":[20],"Evolutionary)":[21],"Placement":[22],"methods":[23,43,69,153],"can":[24],"be":[25,84],"employed":[26],"to":[27,36,60,87,98,108,115],"determine":[28],"position":[31],"sequences":[33,54,112],"with":[34],"respect":[35],"a":[37,106,135],"given":[38],"reference":[39,53,62,81,117],"phylogeny.":[40],"These":[41],"placement":[42,162],"do":[44],"however":[45],"face":[46],"certain":[47],"limitations:":[48],"The":[49],"manual":[50],"selection":[51],"is":[55,64],"labor-intensive;":[56],"computational":[58],"effort":[59],"infer":[61,116],"phylogenies":[63],"substantially":[65,154],"larger":[66],"than":[67],"for":[68,89,124,140],"that":[70,138,151],"rely":[71],"on":[72,129,147],"sequence":[73,143],"similarity;":[74],"number":[76],"taxa":[78],"phylogeny":[82],"should":[83],"small":[85],"enough":[86],"allow":[88],"visually":[90],"inspecting":[91],"results.":[93,163],"RESULTS:":[94],"We":[95],"present":[96,121],"algorithms":[97],"overcome":[99],"above":[101],"limitations.":[102],"First,":[103],"we":[104,120,133],"introduce":[105],"method":[107],"automatically":[109],"construct":[110],"representative":[111],"from":[113],"databases":[114],"phylogenies.":[118,131],"Second,":[119],"an":[122],"approach":[123],"conducting":[125],"large-scale":[126],"phylogenetic":[127],"placements":[128],"nested":[130],"Third,":[132],"describe":[134],"preprocessing":[136],"pipeline":[137],"allows":[139],"handling":[141],"huge":[142],"datasets.":[144],"Our":[145],"experiments":[146],"empirical":[148],"data":[149,176],"show":[150],"our":[152],"accelerate":[155],"workflow":[157],"and":[158],"yield":[159],"highly":[160],"accurate":[161],"AVAILABILITY":[164],"AND":[165],"IMPLEMENTATION:":[166],"Freely":[167],"available":[168,178],"under":[169],"GPLv3":[170],"at":[171,179],"http://github.com/lczech/gappa.":[172],"SUPPLEMENTARY":[173],"INFORMATION:":[174],"Supplementary":[175],"are":[177],"Bioinformatics":[180],"online.":[181]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}