{"id":"https://openalex.org/W2887815121","doi":"https://doi.org/10.1093/bioinformatics/bty675","title":"Evaluation of cross-platform and interlaboratory concordance via consensus modelling of genomic measurements","display_name":"Evaluation of cross-platform and interlaboratory concordance via consensus modelling of genomic measurements","publication_year":2018,"publication_date":"2018-07-31","ids":{"openalex":"https://openalex.org/W2887815121","doi":"https://doi.org/10.1093/bioinformatics/bty675","mag":"2887815121","pmid":"https://pubmed.ncbi.nlm.nih.gov/30084929"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/bty675","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bty675","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/4/560/27838576/bty675.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/35/4/560/27838576/bty675.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048022602","display_name":"Timothy J. Peters","orcid":"https://orcid.org/0000-0003-3690-5293"},"institutions":[{"id":"https://openalex.org/I136750679","display_name":"Garvan Institute of Medical Research","ror":"https://ror.org/01b3dvp57","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I136750679","https://openalex.org/I4210087284"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Timothy J Peters","raw_affiliation_strings":["Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I136750679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047409100","display_name":"Hugh J. French","orcid":"https://orcid.org/0000-0001-7464-6929"},"institutions":[{"id":"https://openalex.org/I136750679","display_name":"Garvan Institute of Medical Research","ror":"https://ror.org/01b3dvp57","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I136750679","https://openalex.org/I4210087284"]},{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]},{"id":"https://openalex.org/I4210163551","display_name":"South Western Sydney Local Health District","ror":"https://ror.org/05j37e495","country_code":"AU","type":"government","lineage":["https://openalex.org/I1311436738","https://openalex.org/I2801351115","https://openalex.org/I4210163551"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Hugh J French","raw_affiliation_strings":["Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales, Liverpool, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I136750679"]},{"raw_affiliation_string":"South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales, Liverpool, NSW, Australia","institution_ids":["https://openalex.org/I31746571","https://openalex.org/I4210163551"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013248393","display_name":"Stephen Bradford","orcid":"https://orcid.org/0000-0002-9508-3894"},"institutions":[{"id":"https://openalex.org/I136750679","display_name":"Garvan Institute of Medical Research","ror":"https://ror.org/01b3dvp57","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I136750679","https://openalex.org/I4210087284"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Stephen T Bradford","raw_affiliation_strings":["CSIRO Health and Biosecurity, North Ryde, NSW, Australia","Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSIRO Health and Biosecurity, North Ryde, NSW, Australia","institution_ids":["https://openalex.org/I4210142128"]},{"raw_affiliation_string":"Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I136750679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079320372","display_name":"Ruth Pidsley","orcid":"https://orcid.org/0000-0002-1386-1374"},"institutions":[{"id":"https://openalex.org/I136750679","display_name":"Garvan Institute of Medical Research","ror":"https://ror.org/01b3dvp57","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I136750679","https://openalex.org/I4210087284"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Ruth Pidsley","raw_affiliation_strings":["Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I136750679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004427898","display_name":"Clare Stirzaker","orcid":"https://orcid.org/0000-0001-5601-3140"},"institutions":[{"id":"https://openalex.org/I136750679","display_name":"Garvan Institute of Medical Research","ror":"https://ror.org/01b3dvp57","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I136750679","https://openalex.org/I4210087284"]},{"id":"https://openalex.org/I4210123488","display_name":"St Vincent's Clinic","ror":"https://ror.org/02rthxz10","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210123488"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Clare Stirzaker","raw_affiliation_strings":["Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","St Vincent\u2019s Clinical School, Faculty of Medicine, UNSW, Darlinghurst, NSW, Australia","St Vincent's Clinical School, Faculty of Medicine, UNSW, Darlinghurst, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I136750679"]},{"raw_affiliation_string":"St Vincent\u2019s Clinical School, Faculty of Medicine, UNSW, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I4210123488"]},{"raw_affiliation_string":"St Vincent's Clinical School, Faculty of Medicine, UNSW, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I4210123488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045428479","display_name":"Hilal Varinli","orcid":null},"institutions":[{"id":"https://openalex.org/I1311436738","display_name":"New South Wales Department of Health","ror":"https://ror.org/03tb4gf50","country_code":"AU","type":"government","lineage":["https://openalex.org/I1311436738","https://openalex.org/I2801351115"]},{"id":"https://openalex.org/I136750679","display_name":"Garvan Institute of Medical Research","ror":"https://ror.org/01b3dvp57","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I136750679","https://openalex.org/I4210087284"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I99043593","display_name":"Macquarie University","ror":"https://ror.org/01sf06y89","country_code":"AU","type":"education","lineage":["https://openalex.org/I99043593"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Hilal Varinli","raw_affiliation_strings":["CSIRO Health and Biosecurity, North Ryde, NSW, Australia","Department of Biological Sciences, Macquarie University, North Ryde, NSW, Australia","Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","NSW Ministry of Health, LMB 961, North Sydney, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSIRO Health and Biosecurity, North Ryde, NSW, Australia","institution_ids":["https://openalex.org/I4210142128"]},{"raw_affiliation_string":"Department of Biological Sciences, Macquarie University, North Ryde, NSW, Australia","institution_ids":["https://openalex.org/I99043593"]},{"raw_affiliation_string":"Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I136750679"]},{"raw_affiliation_string":"NSW Ministry of Health, LMB 961, North Sydney, NSW, Australia","institution_ids":["https://openalex.org/I1311436738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112382666","display_name":"Shalima S. Nair","orcid":null},"institutions":[{"id":"https://openalex.org/I136750679","display_name":"Garvan Institute of Medical Research","ror":"https://ror.org/01b3dvp57","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I136750679","https://openalex.org/I4210087284"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Shalima Nair","raw_affiliation_strings":["Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I136750679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112904397","display_name":"Wenjia Qu","orcid":null},"institutions":[{"id":"https://openalex.org/I136750679","display_name":"Garvan Institute of Medical Research","ror":"https://ror.org/01b3dvp57","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I136750679","https://openalex.org/I4210087284"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Wenjia Qu","raw_affiliation_strings":["Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I136750679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032138494","display_name":"Jenny Z. Song","orcid":null},"institutions":[{"id":"https://openalex.org/I136750679","display_name":"Garvan Institute of Medical Research","ror":"https://ror.org/01b3dvp57","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I136750679","https://openalex.org/I4210087284"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jenny Song","raw_affiliation_strings":["Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I136750679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063623863","display_name":"Katherine A. Giles","orcid":"https://orcid.org/0000-0001-5909-5452"},"institutions":[{"id":"https://openalex.org/I136750679","display_name":"Garvan Institute of Medical Research","ror":"https://ror.org/01b3dvp57","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I136750679","https://openalex.org/I4210087284"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Katherine A Giles","raw_affiliation_strings":["Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I136750679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050873859","display_name":"Aaron L. Statham","orcid":null},"institutions":[{"id":"https://openalex.org/I136750679","display_name":"Garvan Institute of Medical Research","ror":"https://ror.org/01b3dvp57","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I136750679","https://openalex.org/I4210087284"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Aaron L Statham","raw_affiliation_strings":["Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I136750679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111838582","display_name":"H. J. L. Speirs","orcid":null},"institutions":[{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Helen Speirs","raw_affiliation_strings":["Ramaciotti Centre for Genomics, University of New South Wales, Randwick, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ramaciotti Centre for Genomics, University of New South Wales, Randwick, NSW, Australia","institution_ids":["https://openalex.org/I31746571"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001135422","display_name":"Terence P. Speed","orcid":"https://orcid.org/0000-0002-5403-7998"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I196021976","display_name":"Walter and Eliza Hall Institute of Medical Research","ror":"https://ror.org/01b6kha49","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I196021976"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Terence P Speed","raw_affiliation_strings":["Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia","Department of Mathematics & Statistics, University of Melbourne, Melbourne, VIC, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia","institution_ids":["https://openalex.org/I196021976"]},{"raw_affiliation_string":"Department of Mathematics & Statistics, University of Melbourne, Melbourne, VIC, Australia","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041095680","display_name":"Susan J. Clark","orcid":"https://orcid.org/0000-0001-5925-5030"},"institutions":[{"id":"https://openalex.org/I136750679","display_name":"Garvan Institute of Medical Research","ror":"https://ror.org/01b3dvp57","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I136750679","https://openalex.org/I4210087284"]},{"id":"https://openalex.org/I4210123488","display_name":"St Vincent's Clinic","ror":"https://ror.org/02rthxz10","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210123488"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Susan J Clark","raw_affiliation_strings":["Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","St Vincent\u2019s Clinical School, Faculty of Medicine, UNSW, Darlinghurst, NSW, Australia","St Vincent's Clinical School, Faculty of Medicine, UNSW, Darlinghurst, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epigenetics Laboratory, Genomics and Epigenetics Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I136750679"]},{"raw_affiliation_string":"St Vincent\u2019s Clinical School, Faculty of Medicine, UNSW, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I4210123488"]},{"raw_affiliation_string":"St Vincent's Clinical School, Faculty of Medicine, UNSW, Darlinghurst, NSW, Australia","institution_ids":["https://openalex.org/I4210123488"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5048022602"],"corresponding_institution_ids":["https://openalex.org/I136750679"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":0.8017,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.75660826,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"35","issue":"4","first_page":"560","last_page":"570"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.4896000027656555,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.4896000027656555,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.14740000665187836,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.08179999887943268,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5565447807312012},{"id":"https://openalex.org/keywords/locus","display_name":"Locus (genetics)","score":0.5183969140052795},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4867822825908661},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.45447075366973877},{"id":"https://openalex.org/keywords/bisulfite-sequencing","display_name":"Bisulfite sequencing","score":0.41285815834999084},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.38682791590690613},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.35896575450897217},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.34541207551956177},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.22857090830802917},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.08229213953018188}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5565447807312012},{"id":"https://openalex.org/C84597430","wikidata":"https://www.wikidata.org/wiki/Q106227","display_name":"Locus (genetics)","level":3,"score":0.5183969140052795},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4867822825908661},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.45447075366973877},{"id":"https://openalex.org/C189235521","wikidata":"https://www.wikidata.org/wiki/Q4087270","display_name":"Bisulfite sequencing","level":5,"score":0.41285815834999084},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38682791590690613},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.35896575450897217},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.34541207551956177},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.22857090830802917},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.08229213953018188}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1093/bioinformatics/bty675","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bty675","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/4/560/27838576/bty675.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:30084929","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30084929","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:unsworks.library.unsw.edu.au:1959.4/unsworks_63978","is_oa":true,"landing_page_url":"http://hdl.handle.net/1959.4/unsworks_63978","pdf_url":"https://unsworks.unsw.edu.au/bitstreams/1060d1bd-61e8-435b-a077-359db6bc46f4/download","source":{"id":"https://openalex.org/S4306401737","display_name":"UNSWorks (University of New South Wales, Sydney, Australia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I40053085","host_organization_name":"Australian Defence Force Academy","host_organization_lineage":["https://openalex.org/I40053085"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics, 35, 4, 560-570","raw_type":"http://purl.org/coar/resource_type/c_6501"},{"id":"pmh:oai:jupiter.its.unimelb.edu.au:11343/271038","is_oa":true,"landing_page_url":"http://hdl.handle.net/11343/271038","pdf_url":"http://hdl.handle.net/11343/271038","source":{"id":"https://openalex.org/S4377196259","display_name":"Minerva Access (University of Melbourne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I165779595","host_organization_name":"The University of Melbourne","host_organization_lineage":["https://openalex.org/I165779595"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5381123","is_oa":false,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6378945","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6378945","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6378945","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/bty675","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bty675","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/4/560/27838576/bty675.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/17","score":0.4399999976158142,"display_name":"Partnerships for the goals"}],"awards":[{"id":"https://openalex.org/G1254732888","display_name":"Bioinformatics for medical \u201comics\u201d","funder_award_id":"1054618","funder_id":"https://openalex.org/F4320334705","funder_display_name":"National Health and Medical Research Council"},{"id":"https://openalex.org/G1745072654","display_name":"Epigenetic Changes in the Prostate Cancer Microenvironment","funder_award_id":"1106870","funder_id":"https://openalex.org/F4320334705","funder_display_name":"National Health and Medical Research Council"},{"id":"https://openalex.org/G1875802766","display_name":null,"funder_award_id":"RP03-064","funder_id":"https://openalex.org/F4320310744","funder_display_name":"Science and Industry Endowment Fund"},{"id":"https://openalex.org/G3801095338","display_name":"DNA METHYLATION and DEMETHYLATION IMBALANCE in CANCER","funder_award_id":"1088144","funder_id":"https://openalex.org/F4320334705","funder_display_name":"National Health and Medical Research Council"},{"id":"https://openalex.org/G696131228","display_name":"Determining the causes and consequences of epigenetic remodelling in cancer and disease","funder_award_id":"1063559","funder_id":"https://openalex.org/F4320334705","funder_display_name":"National Health and Medical Research Council"},{"id":"https://openalex.org/G8251801756","display_name":null,"funder_award_id":"1044458","funder_id":"https://openalex.org/F4320320501","funder_display_name":"Cancer Australia"}],"funders":[{"id":"https://openalex.org/F4320310744","display_name":"Science and Industry Endowment Fund","ror":"https://ror.org/04c4mj004"},{"id":"https://openalex.org/F4320313900","display_name":"National Defense Medical College","ror":"https://ror.org/02e4qbj88"},{"id":"https://openalex.org/F4320315379","display_name":"Australian Prostate Cancer Research","ror":null},{"id":"https://openalex.org/F4320320386","display_name":"Commonwealth Scientific and Industrial Research Organisation","ror":"https://ror.org/03qn8fb07"},{"id":"https://openalex.org/F4320320438","display_name":"National Breast Cancer Foundation","ror":"https://ror.org/0120ky124"},{"id":"https://openalex.org/F4320320501","display_name":"Cancer Australia","ror":"https://ror.org/00510tw04"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","ror":"https://ror.org/011kf5r70"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2887815121.pdf","grobid_xml":"https://content.openalex.org/works/W2887815121.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W1156633656","https://openalex.org/W1515242458","https://openalex.org/W1534357707","https://openalex.org/W1565693361","https://openalex.org/W1915087491","https://openalex.org/W1937618727","https://openalex.org/W1975528145","https://openalex.org/W1987470886","https://openalex.org/W1987777080","https://openalex.org/W1989996002","https://openalex.org/W2009458183","https://openalex.org/W2010637767","https://openalex.org/W2012561822","https://openalex.org/W2013990566","https://openalex.org/W2017502278","https://openalex.org/W2027662464","https://openalex.org/W2050105063","https://openalex.org/W2059099579","https://openalex.org/W2064397275","https://openalex.org/W2066044951","https://openalex.org/W2067151470","https://openalex.org/W2073380432","https://openalex.org/W2107665951","https://openalex.org/W2129915465","https://openalex.org/W2134744211","https://openalex.org/W2135046866","https://openalex.org/W2135157239","https://openalex.org/W2137499573","https://openalex.org/W2139318043","https://openalex.org/W2141009231","https://openalex.org/W2141688036","https://openalex.org/W2160444236","https://openalex.org/W2161289668","https://openalex.org/W2164131361","https://openalex.org/W2406493898","https://openalex.org/W2515569507","https://openalex.org/W2527109958","https://openalex.org/W2529024004","https://openalex.org/W2575775275","https://openalex.org/W2589050468","https://openalex.org/W2606715885","https://openalex.org/W2624237725","https://openalex.org/W2798082234","https://openalex.org/W2913614465","https://openalex.org/W2949771015","https://openalex.org/W2963253266","https://openalex.org/W4211209398"],"related_works":["https://openalex.org/W2050726229","https://openalex.org/W1979814181","https://openalex.org/W2950845984","https://openalex.org/W2900173251","https://openalex.org/W2757034914","https://openalex.org/W2467814536","https://openalex.org/W2126992172","https://openalex.org/W2787468300","https://openalex.org/W2960556654","https://openalex.org/W2103759706"],"abstract_inverted_index":{"MOTIVATION:":[0],"A":[1,250],"synoptic":[2],"view":[3],"of":[4,13,24,37,47,82,95,99,116,132,152,199,201,216,221,235,253],"the":[5,11,34,80,90,108,117,162,193,202,219,239,254,265],"human":[6],"genome":[7,167],"benefits":[8],"chiefly":[9],"from":[10],"application":[12,115],"nucleic":[14],"acid":[15],"sequencing":[16,169],"and":[17,30,43,93,122,130,140,154,176,178],"microarray":[18],"technologies.":[19],"These":[20],"platforms":[21],"allow":[22],"interrogation":[23],"patterns":[25],"such":[26],"as":[27],"gene":[28,181],"expression":[29,182],"DNA":[31],"methylation":[32,223],"at":[33,269,277],"vast":[35],"majority":[36],"canonical":[38],"loci,":[39,149],"allowing":[40,150],"granular":[41],"insights":[42],"opportunities":[44],"for":[45,120,126,260],"validation":[46],"original":[48],"findings.":[49],"However,":[50],"problems":[51],"arise":[52],"when":[53],"validating":[54],"against":[55],"a":[56,83,96,103,197,213,228,233],"\"gold":[57,84],"standard\"":[58,85],"measurement,":[59],"since":[60],"this":[61],"immediately":[62],"biases":[63],"all":[64,74,147],"subsequent":[65],"measurements":[66,76],"towards":[67],"that":[68],"particular":[69],"technology":[70,186],"or":[71],"protocol.":[72],"Since":[73],"genomic":[75,100],"are":[77,262,275],"estimates,":[78],"in":[79,264],"absence":[81],"we":[86,226],"instead":[87],"empirically":[88],"assess":[89,159],"measurement":[91],"precision":[92,129],"sensitivity":[94,220],"large":[97],"suite":[98],"technologies":[101,160],"via":[102],"consensus":[104,268],"modelling":[105],"method":[106,112],"called":[107],"row-linear":[109,203,255],"model.":[110],"This":[111],"is":[113,188],"an":[114],"American":[118],"Society":[119],"Testing":[121],"Materials":[123],"Standard":[124],"E691":[125],"assessing":[127],"interlaboratory":[128,230],"sources":[131],"variability":[133],"across":[134,146,242],"multiple":[135],"testing":[136,245],"sites.":[137],"Both":[138],"cross-platform":[139],"cross-locus":[141],"comparisons":[142],"can":[143],"be":[144],"made":[145],"common":[148],"identification":[151],"technology-":[153],"locus-specific":[155],"tendencies.":[156],"RESULTS:":[157],"We":[158,195,211],"including":[161,205],"Infinium":[163,222],"MethylationEPIC":[164],"BeadChip,":[165],"whole":[166],"bisulfite":[168],"(WGBS),":[170],"two":[171],"different":[172,180],"RNA-Seq":[173],"protocols":[174],"(PolyA+":[175],"Ribo-Zero)":[177],"five":[179],"array":[183],"platforms.":[184],"Each":[185],"thus":[187],"characterised":[189],"herein,":[190],"relative":[191],"to":[192],"consensus.":[194],"showcase":[196],"number":[198],"applications":[200],"model,":[204,256],"correlation":[206],"with":[207],"known":[208],"interfering":[209],"traits.":[210],"demonstrate":[212],"clear":[214],"effect":[215],"cross-hybridisation":[217],"on":[218,232,238],"arrays.":[224],"Additionally,":[225],"perform":[227],"true":[229],"test":[231],"set":[234],"samples":[236],"interrogated":[237],"same":[240],"platform":[241],"twenty-one":[243],"separate":[244],"laboratories.":[246],"AVAILABILITY":[247],"AND":[248],"IMPLEMENTATION:":[249],"full":[251],"implementation":[252],"plus":[257],"extra":[258],"functions":[259],"visualisation,":[261],"found":[263],"R":[266],"package":[267],"https://github.com/timpeters82/consensus.":[270],"SUPPLEMENTARY":[271],"INFORMATION:":[272],"Supplementary":[273],"data":[274],"available":[276],"Bioinformatics":[278],"online.":[279]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":3}],"updated_date":"2026-08-08T01:25:22.217667","created_date":"2025-10-10T00:00:00"}