{"id":"https://openalex.org/W2953103783","doi":"https://doi.org/10.1093/bioinformatics/bty635","title":"SKEMPI 2.0: an updated benchmark of changes in protein\u2013protein binding energy, kinetics and thermodynamics upon mutation","display_name":"SKEMPI 2.0: an updated benchmark of changes in protein\u2013protein binding energy, kinetics and thermodynamics upon mutation","publication_year":2018,"publication_date":"2018-07-18","ids":{"openalex":"https://openalex.org/W2953103783","doi":"https://doi.org/10.1093/bioinformatics/bty635","mag":"2953103783","pmid":"https://pubmed.ncbi.nlm.nih.gov/30020414"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/bty635","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bty635","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1093/bioinformatics/bty635","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088572483","display_name":"Justina Jankauskait\u0117","orcid":null},"institutions":[{"id":"https://openalex.org/I173212132","display_name":"Vilnius University","ror":"https://ror.org/03nadee84","country_code":"LT","type":"education","lineage":["https://openalex.org/I173212132"]}],"countries":["LT"],"is_corresponding":false,"raw_author_name":"Justina Jankauskait\u0117","raw_affiliation_strings":["Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius, Lithuania"],"affiliations":[{"raw_affiliation_string":"Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius, Lithuania","institution_ids":["https://openalex.org/I173212132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012374366","display_name":"Brian Jim\u00e9nez\u2010Garc\u00eda","orcid":"https://orcid.org/0000-0001-7786-2109"},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES","NL"],"is_corresponding":false,"raw_author_name":"Brian Jim\u00e9nez-Garc\u00eda","raw_affiliation_strings":["Barcelona Supercomputing Center (BSC), Barcelona, Spain","Bijvoet Center for Biomolecular Research, Faculty of Science, Utrecht University, Utrecht, the Netherlands"],"affiliations":[{"raw_affiliation_string":"Barcelona Supercomputing Center (BSC), Barcelona, Spain","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]},{"raw_affiliation_string":"Bijvoet Center for Biomolecular Research, Faculty of Science, Utrecht University, Utrecht, the Netherlands","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091513476","display_name":"Justas Dapk\u016bnas","orcid":"https://orcid.org/0000-0002-0496-6107"},"institutions":[{"id":"https://openalex.org/I173212132","display_name":"Vilnius University","ror":"https://ror.org/03nadee84","country_code":"LT","type":"education","lineage":["https://openalex.org/I173212132"]}],"countries":["LT"],"is_corresponding":false,"raw_author_name":"Justas Dapk\u016bnas","raw_affiliation_strings":["Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius, Lithuania"],"affiliations":[{"raw_affiliation_string":"Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius, Lithuania","institution_ids":["https://openalex.org/I173212132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021117369","display_name":"Juan Fern\u00e1ndez\u2010Recio","orcid":"https://orcid.org/0000-0002-3986-7686"},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I4210166526","display_name":"Institut de Biologia Molecular de Barcelona","ror":"https://ror.org/05t8khn72","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I4210166526"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Juan Fern\u00e1ndez-Recio","raw_affiliation_strings":["Barcelona Supercomputing Center (BSC), Barcelona, Spain","Institut de Biologia Molecular de Barcelona (IBMB), CSIC, Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Barcelona Supercomputing Center (BSC), Barcelona, Spain","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]},{"raw_affiliation_string":"Institut de Biologia Molecular de Barcelona (IBMB), CSIC, Barcelona, Spain","institution_ids":["https://openalex.org/I4210166526"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060836019","display_name":"Iain H. Moal","orcid":"https://orcid.org/0000-0002-4960-5487"},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Iain H Moal","raw_affiliation_strings":["European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridge, UK"],"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridge, UK","institution_ids":["https://openalex.org/I1303153112"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5060836019"],"corresponding_institution_ids":["https://openalex.org/I1303153112"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":10.0535,"has_fulltext":false,"cited_by_count":376,"citation_normalized_percentile":{"value":0.9887246,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"35","issue":"3","first_page":"462","last_page":"469"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9962000250816345,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kinetics","display_name":"Kinetics","score":0.6123900413513184},{"id":"https://openalex.org/keywords/mutation","display_name":"Mutation","score":0.5791640281677246},{"id":"https://openalex.org/keywords/protein-data-bank","display_name":"Protein Data Bank","score":0.4842948317527771},{"id":"https://openalex.org/keywords/enthalpy","display_name":"Enthalpy","score":0.4801880121231079},{"id":"https://openalex.org/keywords/binding-energy","display_name":"Binding energy","score":0.4748292863368988},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4670411944389343},{"id":"https://openalex.org/keywords/entropy","display_name":"Entropy (arrow of time)","score":0.42479458451271057},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.39957892894744873},{"id":"https://openalex.org/keywords/thermodynamics","display_name":"Thermodynamics","score":0.38664156198501587},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.3776821196079254},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.30804550647735596},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.2265392541885376},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.1632879376411438},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.14781349897384644}],"concepts":[{"id":"https://openalex.org/C148898269","wikidata":"https://www.wikidata.org/wiki/Q1108792","display_name":"Kinetics","level":2,"score":0.6123900413513184},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.5791640281677246},{"id":"https://openalex.org/C119145174","wikidata":"https://www.wikidata.org/wiki/Q7251429","display_name":"Protein Data Bank","level":3,"score":0.4842948317527771},{"id":"https://openalex.org/C3288061","wikidata":"https://www.wikidata.org/wiki/Q161064","display_name":"Enthalpy","level":2,"score":0.4801880121231079},{"id":"https://openalex.org/C93282013","wikidata":"https://www.wikidata.org/wiki/Q420754","display_name":"Binding energy","level":2,"score":0.4748292863368988},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4670411944389343},{"id":"https://openalex.org/C106301342","wikidata":"https://www.wikidata.org/wiki/Q4117933","display_name":"Entropy (arrow of time)","level":2,"score":0.42479458451271057},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39957892894744873},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.38664156198501587},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.3776821196079254},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30804550647735596},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2265392541885376},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1632879376411438},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14781349897384644},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.1093/bioinformatics/bty635","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bty635","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:30020414","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30020414","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:6361233","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6361233","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:upcommons.upc.edu:2117/123759","is_oa":true,"landing_page_url":"https://hdl.handle.net/2117/123759","pdf_url":null,"source":{"id":"https://openalex.org/S4210207057","display_name":"QRU Quaderns de Recerca en Urbanisme","issn_l":"2014-9689","issn":["2014-9689","2385-6777"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/P4310322448","host_organization_name":"Q71272178","host_organization_lineage":["https://openalex.org/P4310322448"],"host_organization_lineage_names":["Q71272178"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:digital.csic.es:10261/201745","is_oa":false,"landing_page_url":"http://hdl.handle.net/10261/201745","pdf_url":null,"source":{"id":"https://openalex.org/S4306400616","display_name":"DIGITAL.CSIC (Spanish National Research Council (CSIC))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I134820265","host_organization_name":"Consejo Superior de Investigaciones Cient\u00edficas","host_organization_lineage":["https://openalex.org/I134820265"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"art\u00edculo"},{"id":"pmh:oai:europepmc.org:5356726","is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6361233","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:portal.dialnet.es:doc/5da053562999523b6cbf69ec","is_oa":true,"landing_page_url":"https://investigacion.unirioja.es/documentos/5da053562999523b6cbf69ec","pdf_url":null,"source":{"id":"https://openalex.org/S4306402551","display_name":"RIUR (Universidad de La Rioja)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I3032752892","host_organization_name":"Universidad Internacional de La Rioja","host_organization_lineage":["https://openalex.org/I3032752892"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/bty635","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bty635","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Affordable and clean energy","score":0.7799999713897705,"id":"https://metadata.un.org/sdg/7"}],"awards":[{"id":"https://openalex.org/G1506633613","display_name":null,"funder_award_id":"676566","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G152318085","display_name":null,"funder_award_id":"BIO2016-79930-R","funder_id":"https://openalex.org/F4320321837","funder_display_name":"Ministerio de Econom\u00eda y Competitividad"},{"id":"https://openalex.org/G7894009206","display_name":null,"funder_award_id":"BB/N011600/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320314023","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/050589e39"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321837","display_name":"Ministerio de Econom\u00eda y Competitividad","ror":"https://ror.org/034900433"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":80,"referenced_works":["https://openalex.org/W769759530","https://openalex.org/W1030883578","https://openalex.org/W1566201844","https://openalex.org/W1896347914","https://openalex.org/W1915490970","https://openalex.org/W1970072631","https://openalex.org/W1972511530","https://openalex.org/W1974599488","https://openalex.org/W1978827657","https://openalex.org/W1983659508","https://openalex.org/W1991633284","https://openalex.org/W1993595643","https://openalex.org/W1996078098","https://openalex.org/W1997525701","https://openalex.org/W2008765876","https://openalex.org/W2010512513","https://openalex.org/W2010737876","https://openalex.org/W2013376035","https://openalex.org/W2016755296","https://openalex.org/W2017310049","https://openalex.org/W2017847830","https://openalex.org/W2029370353","https://openalex.org/W2036309115","https://openalex.org/W2037048830","https://openalex.org/W2049275721","https://openalex.org/W2058714876","https://openalex.org/W2062695451","https://openalex.org/W2064878478","https://openalex.org/W2073526502","https://openalex.org/W2074719974","https://openalex.org/W2082006283","https://openalex.org/W2084653587","https://openalex.org/W2085072319","https://openalex.org/W2097271989","https://openalex.org/W2100025509","https://openalex.org/W2102516512","https://openalex.org/W2103459989","https://openalex.org/W2103737249","https://openalex.org/W2108921801","https://openalex.org/W2110270259","https://openalex.org/W2114394047","https://openalex.org/W2117541321","https://openalex.org/W2130479394","https://openalex.org/W2130670576","https://openalex.org/W2133791465","https://openalex.org/W2136778106","https://openalex.org/W2157735020","https://openalex.org/W2157807259","https://openalex.org/W2163052596","https://openalex.org/W2164220181","https://openalex.org/W2166103775","https://openalex.org/W2170304162","https://openalex.org/W2192013059","https://openalex.org/W2283896596","https://openalex.org/W2290394493","https://openalex.org/W2301930322","https://openalex.org/W2345331290","https://openalex.org/W2412612592","https://openalex.org/W2437524902","https://openalex.org/W2463458349","https://openalex.org/W2473896198","https://openalex.org/W2475686134","https://openalex.org/W2554576124","https://openalex.org/W2558870009","https://openalex.org/W2560410107","https://openalex.org/W2564155015","https://openalex.org/W2564946891","https://openalex.org/W2574824017","https://openalex.org/W2588335558","https://openalex.org/W2588962857","https://openalex.org/W2598928857","https://openalex.org/W2605786497","https://openalex.org/W2611381654","https://openalex.org/W2612814374","https://openalex.org/W2623055862","https://openalex.org/W2745143929","https://openalex.org/W2759049238","https://openalex.org/W2780523853","https://openalex.org/W4210309881","https://openalex.org/W6742868720"],"related_works":["https://openalex.org/W3126783617","https://openalex.org/W3093468851","https://openalex.org/W4280624450","https://openalex.org/W2121688928","https://openalex.org/W2732388178","https://openalex.org/W2806488847","https://openalex.org/W2185518315","https://openalex.org/W4388749535","https://openalex.org/W4353055924","https://openalex.org/W1495233806"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":23},{"year":2025,"cited_by_count":83},{"year":2024,"cited_by_count":60},{"year":2023,"cited_by_count":55},{"year":2022,"cited_by_count":47},{"year":2021,"cited_by_count":45},{"year":2020,"cited_by_count":38},{"year":2019,"cited_by_count":18},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":1}],"updated_date":"2026-04-13T07:58:08.660418","created_date":"2025-10-10T00:00:00"}