{"id":"https://openalex.org/W2790305479","doi":"https://doi.org/10.1093/bioinformatics/bty054","title":"MutHTP: mutations in human transmembrane proteins","display_name":"MutHTP: mutations in human transmembrane proteins","publication_year":2018,"publication_date":"2018-01-31","ids":{"openalex":"https://openalex.org/W2790305479","doi":"https://doi.org/10.1093/bioinformatics/bty054","mag":"2790305479","pmid":"https://pubmed.ncbi.nlm.nih.gov/29401218"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/bty054","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bty054","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047094478","display_name":"A. Kulandaisamy","orcid":"https://orcid.org/0000-0002-3367-2669"},"institutions":[{"id":"https://openalex.org/I24676775","display_name":"Indian Institute of Technology Madras","ror":"https://ror.org/03v0r5n49","country_code":"IN","type":"facility","lineage":["https://openalex.org/I24676775"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"A Kulandaisamy","raw_affiliation_strings":["Department of Biotechnology, Bhupat and Jyoti Mehta School of BioSciences, Indian Institute of Technology Madras, Chennai, Tamilnadu, India"],"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Bhupat and Jyoti Mehta School of BioSciences, Indian Institute of Technology Madras, Chennai, Tamilnadu, India","institution_ids":["https://openalex.org/I24676775"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091796665","display_name":"S. Binny Priya","orcid":null},"institutions":[{"id":"https://openalex.org/I24676775","display_name":"Indian Institute of Technology Madras","ror":"https://ror.org/03v0r5n49","country_code":"IN","type":"facility","lineage":["https://openalex.org/I24676775"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"S Binny Priya","raw_affiliation_strings":["Department of Biotechnology, Bhupat and Jyoti Mehta School of BioSciences, Indian Institute of Technology Madras, Chennai, Tamilnadu, India"],"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Bhupat and Jyoti Mehta School of BioSciences, Indian Institute of Technology Madras, Chennai, Tamilnadu, India","institution_ids":["https://openalex.org/I24676775"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103230891","display_name":"Ramasamy Sakthivel","orcid":"https://orcid.org/0009-0001-5281-1206"},"institutions":[{"id":"https://openalex.org/I24676775","display_name":"Indian Institute of Technology Madras","ror":"https://ror.org/03v0r5n49","country_code":"IN","type":"facility","lineage":["https://openalex.org/I24676775"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"R Sakthivel","raw_affiliation_strings":["Department of Biotechnology, Bhupat and Jyoti Mehta School of BioSciences, Indian Institute of Technology Madras, Chennai, Tamilnadu, India"],"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Bhupat and Jyoti Mehta School of BioSciences, Indian Institute of Technology Madras, Chennai, Tamilnadu, India","institution_ids":["https://openalex.org/I24676775"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075025846","display_name":"S. I. Tarnovskaya","orcid":"https://orcid.org/0000-0002-6777-0785"},"institutions":[{"id":"https://openalex.org/I212220629","display_name":"Peter the Great St. Petersburg Polytechnic University","ror":"https://ror.org/02x91aj62","country_code":"RU","type":"education","lineage":["https://openalex.org/I212220629"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Svetlana Tarnovskaya","raw_affiliation_strings":["Department of Bioinformatics, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation","institution_ids":["https://openalex.org/I212220629"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085272251","display_name":"Ilya V. Bizin","orcid":"https://orcid.org/0000-0002-2216-4845"},"institutions":[{"id":"https://openalex.org/I212220629","display_name":"Peter the Great St. Petersburg Polytechnic University","ror":"https://ror.org/02x91aj62","country_code":"RU","type":"education","lineage":["https://openalex.org/I212220629"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Ilya Bizin","raw_affiliation_strings":["Department of Bioinformatics, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation","institution_ids":["https://openalex.org/I212220629"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020154626","display_name":"Peter H\u00f6nigschmid","orcid":null},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Peter H\u00f6nigschmid","raw_affiliation_strings":["Department of Bioinformatics, Technische Universit\u00e4t M\u00fcnchen, WissenschaftszentrumWeihenstephan, Freising, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Technische Universit\u00e4t M\u00fcnchen, WissenschaftszentrumWeihenstephan, Freising, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060795824","display_name":"Dmitrij Frishman","orcid":"https://orcid.org/0000-0002-9006-4707"},"institutions":[{"id":"https://openalex.org/I212220629","display_name":"Peter the Great St. Petersburg Polytechnic University","ror":"https://ror.org/02x91aj62","country_code":"RU","type":"education","lineage":["https://openalex.org/I212220629"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE","RU"],"is_corresponding":false,"raw_author_name":"Dmitrij Frishman","raw_affiliation_strings":["Department of Bioinformatics, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation","Department of Bioinformatics, Technische Universit\u00e4t M\u00fcnchen, WissenschaftszentrumWeihenstephan, Freising, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation","institution_ids":["https://openalex.org/I212220629"]},{"raw_affiliation_string":"Department of Bioinformatics, Technische Universit\u00e4t M\u00fcnchen, WissenschaftszentrumWeihenstephan, Freising, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046879365","display_name":"M. Michael Gromiha","orcid":"https://orcid.org/0000-0002-1776-4096"},"institutions":[{"id":"https://openalex.org/I114531698","display_name":"Tokyo Institute of Technology","ror":"https://ror.org/0112mx960","country_code":"JP","type":"education","lineage":["https://openalex.org/I114531698"]},{"id":"https://openalex.org/I24676775","display_name":"Indian Institute of Technology Madras","ror":"https://ror.org/03v0r5n49","country_code":"IN","type":"facility","lineage":["https://openalex.org/I24676775"]}],"countries":["IN","JP"],"is_corresponding":true,"raw_author_name":"M Michael Gromiha","raw_affiliation_strings":["Advanced Computational Drug Discovery Unit (CADD), Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Kanagawa, Japan","Department of Biotechnology, Bhupat and Jyoti Mehta School of BioSciences, Indian Institute of Technology Madras, Chennai, Tamilnadu, India"],"affiliations":[{"raw_affiliation_string":"Advanced Computational Drug Discovery Unit (CADD), Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Kanagawa, Japan","institution_ids":["https://openalex.org/I114531698"]},{"raw_affiliation_string":"Department of Biotechnology, Bhupat and Jyoti Mehta School of BioSciences, Indian Institute of Technology Madras, Chennai, Tamilnadu, India","institution_ids":["https://openalex.org/I24676775"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5046879365"],"corresponding_institution_ids":["https://openalex.org/I114531698","https://openalex.org/I24676775"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":1.195,"has_fulltext":false,"cited_by_count":35,"citation_normalized_percentile":{"value":0.78164248,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"34","issue":"13","first_page":"2325","last_page":"2326"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/javascript","display_name":"JavaScript","score":0.7052494287490845},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.659080982208252},{"id":"https://openalex.org/keywords/mutation","display_name":"Mutation","score":0.5787362456321716},{"id":"https://openalex.org/keywords/transmembrane-protein","display_name":"Transmembrane protein","score":0.5242900252342224},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.5196208357810974},{"id":"https://openalex.org/keywords/redundancy","display_name":"Redundancy (engineering)","score":0.5149365067481995},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.46068480610847473},{"id":"https://openalex.org/keywords/membrane-protein","display_name":"Membrane protein","score":0.45632198452949524},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.39963454008102417},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.3554641604423523},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3455755114555359},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2568815350532532},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.24424785375595093},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.23477140069007874},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.11939269304275513},{"id":"https://openalex.org/keywords/membrane","display_name":"Membrane","score":0.076386958360672}],"concepts":[{"id":"https://openalex.org/C544833334","wikidata":"https://www.wikidata.org/wiki/Q2005","display_name":"JavaScript","level":2,"score":0.7052494287490845},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.659080982208252},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.5787362456321716},{"id":"https://openalex.org/C24530287","wikidata":"https://www.wikidata.org/wiki/Q424204","display_name":"Transmembrane protein","level":3,"score":0.5242900252342224},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.5196208357810974},{"id":"https://openalex.org/C152124472","wikidata":"https://www.wikidata.org/wiki/Q1204361","display_name":"Redundancy (engineering)","level":2,"score":0.5149365067481995},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.46068480610847473},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.45632198452949524},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.39963454008102417},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.3554641604423523},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3455755114555359},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2568815350532532},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.24424785375595093},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.23477140069007874},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11939269304275513},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.076386958360672},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/bty054","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bty054","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:29401218","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29401218","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1982509624","display_name":null,"funder_award_id":"16-44-02002","funder_id":"https://openalex.org/F4320324099","funder_display_name":"Russian Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320324099","display_name":"Russian Science Foundation","ror":"https://ror.org/03y2gwe85"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W2005626023","https://openalex.org/W2008091140","https://openalex.org/W2011703027","https://openalex.org/W2047663485","https://openalex.org/W2072470496","https://openalex.org/W2074370114","https://openalex.org/W2083268592","https://openalex.org/W2089478756","https://openalex.org/W2104549677","https://openalex.org/W2105537627","https://openalex.org/W2106056376","https://openalex.org/W2118151336","https://openalex.org/W2128710769","https://openalex.org/W2132109794","https://openalex.org/W2135694691","https://openalex.org/W2154866190","https://openalex.org/W2256016639","https://openalex.org/W2472351724","https://openalex.org/W2544136853","https://openalex.org/W2734926260"],"related_works":["https://openalex.org/W1977121829","https://openalex.org/W2097747021","https://openalex.org/W2075741622","https://openalex.org/W2129838159","https://openalex.org/W1974240269","https://openalex.org/W1550113321","https://openalex.org/W2107584639","https://openalex.org/W2044159875","https://openalex.org/W2300916991","https://openalex.org/W2003037477"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":6}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}