{"id":"https://openalex.org/W2753374271","doi":"https://doi.org/10.1093/bioinformatics/btx555","title":"LightDock: a new multi-scale approach to protein\u2013protein docking","display_name":"LightDock: a new multi-scale approach to protein\u2013protein docking","publication_year":2017,"publication_date":"2017-09-01","ids":{"openalex":"https://openalex.org/W2753374271","doi":"https://doi.org/10.1093/bioinformatics/btx555","mag":"2753374271"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btx555","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btx555","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/34/1/49/25113700/btx555.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/34/1/49/25113700/btx555.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012374366","display_name":"Brian Jim\u00e9nez\u2010Garc\u00eda","orcid":"https://orcid.org/0000-0001-7786-2109"},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Brian Jim\u00e9nez-Garc\u00eda","raw_affiliation_strings":["Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona, Spain","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086790564","display_name":"Jorge Roel\u2010Touris","orcid":"https://orcid.org/0000-0002-6588-624X"},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jorge Roel-Touris","raw_affiliation_strings":["Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona, Spain","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050289106","display_name":"Miguel Romero\u2010Durana","orcid":"https://orcid.org/0000-0001-6779-8553"},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Miguel Romero-Durana","raw_affiliation_strings":["Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona, Spain","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091547255","display_name":"Miquel Vidal","orcid":"https://orcid.org/0000-0002-1973-8289"},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Miquel Vidal","raw_affiliation_strings":["Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona, Spain","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084498827","display_name":"Daniel Jim\u00e9nez-Gonz\u00e1lez","orcid":null},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Daniel Jim\u00e9nez-Gonz\u00e1lez","raw_affiliation_strings":["Department of Computer Architecture, Universitat Polit\u00e8cnica de Catalunya, Barcelona, Spain","Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Department of Computer Architecture, Universitat Polit\u00e8cnica de Catalunya, Barcelona, Spain","institution_ids":["https://openalex.org/I9617848"]},{"raw_affiliation_string":"Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona, Spain","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021117369","display_name":"Juan Fern\u00e1ndez\u2010Recio","orcid":"https://orcid.org/0000-0002-3986-7686"},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I4210166526","display_name":"Institut de Biologia Molecular de Barcelona","ror":"https://ror.org/05t8khn72","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I4210166526"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Juan Fern\u00e1ndez-Recio","raw_affiliation_strings":["Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona, Spain","Structural Biology Unit, IBMB-CSIC, Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Life Sciences Department, Barcelona Supercomputing Center (BSC), Barcelona, Spain","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]},{"raw_affiliation_string":"Structural Biology Unit, IBMB-CSIC, Barcelona, Spain","institution_ids":["https://openalex.org/I4210166526"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5021117369"],"corresponding_institution_ids":["https://openalex.org/I2799803557","https://openalex.org/I4210166526","https://openalex.org/I9617848"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":7.0555,"has_fulltext":true,"cited_by_count":139,"citation_normalized_percentile":{"value":0.96971831,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"34","issue":"1","first_page":"49","last_page":"55"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.9900000095367432,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.9900000095367432,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9898999929428101,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12996","display_name":"Cancer Research and Treatments","score":0.9873999953269958,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/docking","display_name":"Docking (animal)","score":0.7778253555297852},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6316593289375305},{"id":"https://openalex.org/keywords/protein\u2013ligand-docking","display_name":"Protein\u2013ligand docking","score":0.5068116784095764},{"id":"https://openalex.org/keywords/macromolecular-docking","display_name":"Macromolecular docking","score":0.42633140087127686},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.34944820404052734},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.3033324182033539},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.19160166382789612},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.1623930037021637},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.15133914351463318},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.09183180332183838},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.08505335450172424},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.06336325407028198},{"id":"https://openalex.org/keywords/virtual-screening","display_name":"Virtual screening","score":0.05335196852684021}],"concepts":[{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.7778253555297852},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6316593289375305},{"id":"https://openalex.org/C77319485","wikidata":"https://www.wikidata.org/wiki/Q7251520","display_name":"Protein\u2013ligand docking","level":4,"score":0.5068116784095764},{"id":"https://openalex.org/C116887118","wikidata":"https://www.wikidata.org/wiki/Q836685","display_name":"Macromolecular docking","level":3,"score":0.42633140087127686},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.34944820404052734},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.3033324182033539},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.19160166382789612},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.1623930037021637},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15133914351463318},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.09183180332183838},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08505335450172424},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.06336325407028198},{"id":"https://openalex.org/C103697762","wikidata":"https://www.wikidata.org/wiki/Q4112105","display_name":"Virtual screening","level":3,"score":0.05335196852684021},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btx555","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btx555","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/34/1/49/25113700/btx555.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmh:oai:upcommons.upc.edu:2117/114893","is_oa":true,"landing_page_url":"https://hdl.handle.net/2117/114893","pdf_url":null,"source":{"id":"https://openalex.org/S4210207057","display_name":"QRU Quaderns de Recerca en Urbanisme","issn_l":"2014-9689","issn":["2014-9689","2385-6777"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/P4310322448","host_organization_name":"Q71272178","host_organization_lineage":["https://openalex.org/P4310322448"],"host_organization_lineage_names":["Q71272178"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:digital.csic.es:10261/174238","is_oa":false,"landing_page_url":"http://hdl.handle.net/10261/174238","pdf_url":null,"source":{"id":"https://openalex.org/S4306400616","display_name":"DIGITAL.CSIC (Spanish National Research Council (CSIC))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I134820265","host_organization_name":"Consejo Superior de Investigaciones Cient\u00edficas","host_organization_lineage":["https://openalex.org/I134820265"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Art\u00edculo"},{"id":"pmh:oai:upcommons.upc.edu:2117/114027","is_oa":true,"landing_page_url":"http://hdl.handle.net/2117/114027","pdf_url":null,"source":{"id":"https://openalex.org/S4210207057","display_name":"QRU Quaderns de Recerca en Urbanisme","issn_l":"2014-9689","issn":["2014-9689","2385-6777"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/P4310322448","host_organization_name":"Q71272178","host_organization_lineage":["https://openalex.org/P4310322448"],"host_organization_lineage_names":["Q71272178"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btx555","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btx555","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/34/1/49/25113700/btx555.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G152318085","display_name":null,"funder_award_id":"BIO2016-79930-R","funder_id":"https://openalex.org/F4320321837","funder_display_name":"Ministerio de Econom\u00eda y Competitividad"},{"id":"https://openalex.org/G178585038","display_name":null,"funder_award_id":"687698","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G2436365243","display_name":null,"funder_award_id":"2014-SGR-1051","funder_id":"https://openalex.org/F4320321505","funder_display_name":"Generalitat de Catalunya"},{"id":"https://openalex.org/G3324247440","display_name":null,"funder_award_id":"TIN2015-65316-P","funder_id":"https://openalex.org/F4320321837","funder_display_name":"Ministerio de Econom\u00eda y Competitividad"},{"id":"https://openalex.org/G4531677044","display_name":null,"funder_award_id":"grant","funder_id":"https://openalex.org/F4320321837","funder_display_name":"Ministerio de Econom\u00eda y Competitividad"},{"id":"https://openalex.org/G4690964475","display_name":null,"funder_award_id":"SEV-2015-0493","funder_id":"https://openalex.org/F4320321837","funder_display_name":"Ministerio de Econom\u00eda y Competitividad"},{"id":"https://openalex.org/G4786115336","display_name":null,"funder_award_id":"-SGR-","funder_id":"https://openalex.org/F4320321505","funder_display_name":"Generalitat de Catalunya"},{"id":"https://openalex.org/G5094957035","display_name":null,"funder_award_id":"fellowship","funder_id":"https://openalex.org/F4320321837","funder_display_name":"Ministerio de Econom\u00eda y Competitividad"},{"id":"https://openalex.org/G5592594182","display_name":null,"funder_award_id":"TIN2015-65316","funder_id":"https://openalex.org/F4320321837","funder_display_name":"Ministerio de Econom\u00eda y Competitividad"},{"id":"https://openalex.org/G7096924396","display_name":null,"funder_award_id":"TIN2015-65316","funder_id":"https://openalex.org/F4320321505","funder_display_name":"Generalitat de Catalunya"},{"id":"https://openalex.org/G7331901853","display_name":null,"funder_award_id":"EU H2020","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G7398056134","display_name":null,"funder_award_id":"2014-SGR-1051","funder_id":"https://openalex.org/F4320321837","funder_display_name":"Ministerio de Econom\u00eda y Competitividad"},{"id":"https://openalex.org/G7422144096","display_name":null,"funder_award_id":"GA 687698","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G8357192574","display_name":null,"funder_award_id":"BIO2013-48213-R","funder_id":"https://openalex.org/F4320321837","funder_display_name":"Ministerio de Econom\u00eda y Competitividad"},{"id":"https://openalex.org/G8714913285","display_name":null,"funder_award_id":"FPI","funder_id":"https://openalex.org/F4320321837","funder_display_name":"Ministerio de Econom\u00eda y Competitividad"}],"funders":[{"id":"https://openalex.org/F4320321505","display_name":"Generalitat de Catalunya","ror":"https://ror.org/01bg62x04"},{"id":"https://openalex.org/F4320321837","display_name":"Ministerio de Econom\u00eda y Competitividad","ror":"https://ror.org/034900433"},{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2753374271.pdf","grobid_xml":"https://content.openalex.org/works/W2753374271.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W13135463","https://openalex.org/W1030883578","https://openalex.org/W1566201844","https://openalex.org/W1601270585","https://openalex.org/W1965379872","https://openalex.org/W1980120676","https://openalex.org/W1993591356","https://openalex.org/W2000383223","https://openalex.org/W2005303195","https://openalex.org/W2009129583","https://openalex.org/W2024911966","https://openalex.org/W2036199279","https://openalex.org/W2055905702","https://openalex.org/W2066244933","https://openalex.org/W2067305633","https://openalex.org/W2073911195","https://openalex.org/W2087485814","https://openalex.org/W2096358531","https://openalex.org/W2099367604","https://openalex.org/W2100025509","https://openalex.org/W2108445825","https://openalex.org/W2112320038","https://openalex.org/W2113994268","https://openalex.org/W2123681603","https://openalex.org/W2125626635","https://openalex.org/W2125677968","https://openalex.org/W2126265982","https://openalex.org/W2136777954","https://openalex.org/W2139319441","https://openalex.org/W2147774191","https://openalex.org/W2152409953","https://openalex.org/W2153731681","https://openalex.org/W2153983456","https://openalex.org/W2160868144","https://openalex.org/W2162682281","https://openalex.org/W2163194931","https://openalex.org/W2165179864","https://openalex.org/W2171778773","https://openalex.org/W2313689636","https://openalex.org/W2332013262","https://openalex.org/W2465190302","https://openalex.org/W4321317585"],"related_works":["https://openalex.org/W1489925612","https://openalex.org/W3011103292","https://openalex.org/W4400485740","https://openalex.org/W2533022751","https://openalex.org/W2064383522","https://openalex.org/W2553094381","https://openalex.org/W2585040066","https://openalex.org/W3187431608","https://openalex.org/W1974422922","https://openalex.org/W4309353019"],"abstract_inverted_index":{"Abstract":[0],"Motivation":[1],"Computational":[2],"prediction":[3],"of":[4,19,53,73,80,102,109,118,149],"protein\u2013protein":[5,97],"complex":[6],"structure":[7],"by":[8],"docking":[9,98],"can":[10],"provide":[11],"structural":[12,49],"and":[13,50,85,106,124,144,152],"mechanistic":[14],"insights":[15],"for":[16,157],"protein":[17],"interactions":[18],"biomedical":[20],"interest.":[21],"However,":[22],"current":[23],"methods":[24],"struggle":[25],"with":[26,133],"difficult":[27],"cases,":[28],"such":[29],"as":[30],"those":[31],"involving":[32],"flexible":[33,141],"proteins,":[34],"low-affinity":[35],"complexes":[36],"or":[37],"transient":[38],"interactions.":[39],"A":[40],"major":[41],"challenge":[42],"is":[43,65],"how":[44],"to":[45,69,135],"efficiently":[46],"sample":[47],"the":[48,54,122,150],"energetic":[51],"landscape":[52],"association":[55],"at":[56,112,159,167],"different":[57,113],"resolution":[58,114],"levels,":[59],"given":[60],"that":[61],"each":[62],"scoring":[63,86,110,127],"function":[64],"often":[66],"highly":[67],"coupled":[68],"a":[70,94,107],"specific":[71],"type":[72],"search":[74,123],"method.":[75],"Thus,":[76],"new":[77,95],"methodologies":[78],"capable":[79,101],"accommodating":[81,103],"multi-scale":[82,96],"conformational":[83,104],"flexibility":[84,105],"are":[87,155,165],"strongly":[88],"needed.":[89],"Results":[90],"We":[91],"describe":[92],"here":[93],"methodology,":[99],"LightDock,":[100],"variety":[108],"functions":[111,128],"levels.":[115],"Implicit":[116],"use":[117],"normal":[119],"modes":[120],"during":[121],"atomic/coarse-grained":[125],"combined":[126],"yielded":[129],"improved":[130],"predictive":[131],"results":[132],"respect":[134],"state-of-the-art":[136],"rigid-body":[137],"docking,":[138],"especially":[139],"in":[140],"cases.":[142],"Availability":[143],"implementation":[145],"The":[146],"source":[147],"code":[148],"software":[151],"installation":[153],"instructions":[154],"available":[156,166],"download":[158],"https://life.bsc.es/pid/lightdock/.":[160],"Supplementary":[161,163],"information":[162],"data":[164],"Bioinformatics":[168],"online.":[169]},"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":24},{"year":2024,"cited_by_count":17},{"year":2023,"cited_by_count":19},{"year":2022,"cited_by_count":21},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":16},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":4}],"updated_date":"2026-04-16T08:26:57.006410","created_date":"2017-09-15T00:00:00"}