{"id":"https://openalex.org/W2668619786","doi":"https://doi.org/10.1093/bioinformatics/btx421","title":"CoreTracker: accurate codon reassignment prediction, applied to mitochondrial genomes","display_name":"CoreTracker: accurate codon reassignment prediction, applied to mitochondrial genomes","publication_year":2017,"publication_date":"2017-06-23","ids":{"openalex":"https://openalex.org/W2668619786","doi":"https://doi.org/10.1093/bioinformatics/btx421","mag":"2668619786","pmid":"https://pubmed.ncbi.nlm.nih.gov/28655158"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btx421","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btx421","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/33/21/3331/25166013/btx421.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/33/21/3331/25166013/btx421.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012750505","display_name":"Emmanuel Noutahi","orcid":"https://orcid.org/0000-0001-5216-9703"},"institutions":[{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Emmanuel Noutahi","raw_affiliation_strings":["D\u00e9partement d'Informatique et de Recherche Op\u00e9rationnelle (DIRO), Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, QC CP, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"D\u00e9partement d'Informatique et de Recherche Op\u00e9rationnelle (DIRO), Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, QC CP, Canada","institution_ids":["https://openalex.org/I70931966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017009855","display_name":"Virginie Calderon","orcid":"https://orcid.org/0000-0002-4267-3452"},"institutions":[{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Virginie Calderon","raw_affiliation_strings":["D\u00e9partement d'Informatique et de Recherche Op\u00e9rationnelle (DIRO), Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, QC CP, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"D\u00e9partement d'Informatique et de Recherche Op\u00e9rationnelle (DIRO), Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, QC CP, Canada","institution_ids":["https://openalex.org/I70931966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065720651","display_name":"Mathieu Blanchette","orcid":"https://orcid.org/0000-0002-9555-860X"},"institutions":[{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Mathieu Blanchette","raw_affiliation_strings":["School of Computer Science, McGill University, McConnell Engineering Bldg., Montr\u00e9al, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science, McGill University, McConnell Engineering Bldg., Montr\u00e9al, QC, Canada","institution_ids":["https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086268010","display_name":"Franz Lang","orcid":null},"institutions":[{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Franz B Lang","raw_affiliation_strings":["D\u00e9partement de Biochimie, Centre Robert Cedergren, Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, QC CP, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"D\u00e9partement de Biochimie, Centre Robert Cedergren, Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, QC CP, Canada","institution_ids":["https://openalex.org/I70931966"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041470344","display_name":"Nadia El-Mabrouk","orcid":"https://orcid.org/0000-0002-5385-1015"},"institutions":[{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Nadia El-Mabrouk","raw_affiliation_strings":["D\u00e9partement d'Informatique et de Recherche Op\u00e9rationnelle (DIRO), Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, QC CP, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"D\u00e9partement d'Informatique et de Recherche Op\u00e9rationnelle (DIRO), Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, QC CP, Canada","institution_ids":["https://openalex.org/I70931966"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5041470344"],"corresponding_institution_ids":["https://openalex.org/I70931966"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.5465,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.6537528,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":97},"biblio":{"volume":"33","issue":"21","first_page":"3331","last_page":"3339"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9110999703407288,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9110999703407288,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.0617000013589859,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.008799999952316284,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.7582775354385376},{"id":"https://openalex.org/keywords/python","display_name":"Python (programming language)","score":0.6170040965080261},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5553101897239685},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.5343612432479858},{"id":"https://openalex.org/keywords/false-positive-paradox","display_name":"False positive paradox","score":0.5296499729156494},{"id":"https://openalex.org/keywords/pointer","display_name":"Pointer (user interface)","score":0.5040034651756287},{"id":"https://openalex.org/keywords/phylogenetic-tree","display_name":"Phylogenetic tree","score":0.4730357825756073},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.45511820912361145},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.45108091831207275},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4395878314971924},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4248162508010864},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.38652101159095764},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3003237843513489},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.28197354078292847},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.18461444973945618},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.1373845636844635}],"concepts":[{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.7582775354385376},{"id":"https://openalex.org/C519991488","wikidata":"https://www.wikidata.org/wiki/Q28865","display_name":"Python (programming language)","level":2,"score":0.6170040965080261},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5553101897239685},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.5343612432479858},{"id":"https://openalex.org/C64869954","wikidata":"https://www.wikidata.org/wiki/Q1859747","display_name":"False positive paradox","level":2,"score":0.5296499729156494},{"id":"https://openalex.org/C150202949","wikidata":"https://www.wikidata.org/wiki/Q107602","display_name":"Pointer (user interface)","level":2,"score":0.5040034651756287},{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.4730357825756073},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.45511820912361145},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.45108091831207275},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4395878314971924},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4248162508010864},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38652101159095764},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3003237843513489},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.28197354078292847},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18461444973945618},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.1373845636844635}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003062","descriptor_name":"Codon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003062","descriptor_name":"Codon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003062","descriptor_name":"Codon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005815","descriptor_name":"Genetic Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005815","descriptor_name":"Genetic Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005815","descriptor_name":"Genetic Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015003","descriptor_name":"Yeasts","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015003","descriptor_name":"Yeasts","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015003","descriptor_name":"Yeasts","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016681","descriptor_name":"Genome, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016681","descriptor_name":"Genome, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016681","descriptor_name":"Genome, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D054629","descriptor_name":"Genome, Mitochondrial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054629","descriptor_name":"Genome, Mitochondrial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054629","descriptor_name":"Genome, Mitochondrial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btx421","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btx421","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/33/21/3331/25166013/btx421.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:28655158","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28655158","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btx421","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btx421","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/33/21/3331/25166013/btx421.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6399999856948853,"id":"https://metadata.un.org/sdg/15","display_name":"Life in Land"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320334841","display_name":"Fonds de recherche du Qu\u00e9bec \u2013 Nature et technologies","ror":"https://ror.org/00b9f9778"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1502060396","https://openalex.org/W1519266993","https://openalex.org/W1594031697","https://openalex.org/W1963800986","https://openalex.org/W1965534094","https://openalex.org/W1986171929","https://openalex.org/W1986211431","https://openalex.org/W1992996520","https://openalex.org/W1995143868","https://openalex.org/W1999151188","https://openalex.org/W2004963253","https://openalex.org/W2006113923","https://openalex.org/W2010512527","https://openalex.org/W2018168677","https://openalex.org/W2018793220","https://openalex.org/W2045804941","https://openalex.org/W2048454561","https://openalex.org/W2053144473","https://openalex.org/W2053731523","https://openalex.org/W2070003197","https://openalex.org/W2073978077","https://openalex.org/W2093840939","https://openalex.org/W2104398544","https://openalex.org/W2111327312","https://openalex.org/W2114395497","https://openalex.org/W2122255902","https://openalex.org/W2122893222","https://openalex.org/W2126848171","https://openalex.org/W2127712523","https://openalex.org/W2138102208","https://openalex.org/W2162160001","https://openalex.org/W2163648372","https://openalex.org/W2163892779","https://openalex.org/W2163924712","https://openalex.org/W2167233594","https://openalex.org/W2171069213","https://openalex.org/W2298792983","https://openalex.org/W2347181167","https://openalex.org/W2401596511","https://openalex.org/W2462560104","https://openalex.org/W2512706593","https://openalex.org/W2525739694","https://openalex.org/W2603860130","https://openalex.org/W2888906255","https://openalex.org/W2911964244"],"related_works":["https://openalex.org/W2341492732","https://openalex.org/W3187193180","https://openalex.org/W106542691","https://openalex.org/W4287027380","https://openalex.org/W1699080303","https://openalex.org/W4297799326","https://openalex.org/W4308823623","https://openalex.org/W2789551765","https://openalex.org/W2367339285","https://openalex.org/W2019168903"],"abstract_inverted_index":{"MOTIVATION:":[0],"Codon":[1],"reassignments":[2,55,106,134],"have":[3],"been":[4],"reported":[5],"across":[6],"all":[7],"domains":[8],"of":[9,15,20,85,98,110,146,159,170],"life.":[10],"With":[11],"the":[12,18,44,96,127,144,147,152,168],"increasing":[13],"number":[14],"sequenced":[16],"genomes,":[17,112,185],"development":[19],"systematic":[21],"approaches":[22],"for":[23,29,95],"genetic":[24,149],"code":[25,150],"detection":[26],"is":[27,200],"essential":[28],"accurate":[30],"downstream":[31],"analyses.":[32],"Three":[33],"automated":[34],"prediction":[35],"tools":[36,61],"exist":[37],"so":[38],"far:":[39],"FACIL,":[40],"GenDecoder":[41],"and":[42,53,71,117,183,194,204],"Bagheera;":[43],"last":[45],"two":[46],"respectively":[47],"restricted":[48],"to":[49,122,130,181],"metazoan":[50,182],"mitochondrial":[51],"genomes":[52,160],"CUG":[54],"in":[56,81,107,161,202],"yeast":[57,184],"nuclear":[58],"genomes.":[59],"These":[60],"can":[62],"only":[63],"analyze":[64],"a":[65,69,77,82,92,108,118,139,157,162],"single":[66],"genome":[67],"at":[68,206,216],"time":[70],"are":[72,126,135,214],"often":[73],"not":[74],"followed":[75],"by":[76],"validation":[78],"procedure,":[79],"resulting":[80],"high":[83],"rate":[84],"false":[86],"positives.":[87],"RESULTS:":[88],"We":[89],"present":[90],"CoreTracker,":[91],"new":[93,148],"algorithm":[94],"inference":[97],"sense-to-sense":[99],"codon":[100,105],"reassignments.":[101],"CoreTracker":[102,186,199],"identifies":[103],"potential":[104],"set":[109,158],"related":[111],"then":[113,136],"uses":[114],"statistical":[115],"evaluations":[116],"random":[119],"forest":[120],"classifier":[121],"predict":[123],"those":[124],"that":[125,142],"most":[128],"likely":[129],"be":[131],"correct.":[132],"Predicted":[133],"validated":[137],"through":[138],"phylogeny-aware":[140],"step":[141],"evaluates":[143],"impact":[145],"on":[151,176,191],"protein":[153],"alignment.":[154],"Handling":[155],"simultaneously":[156],"phylogenetic":[163],"framework,":[164],"allows":[165],"tracing":[166],"back":[167],"evolution":[169],"each":[171],"reassignment,":[172],"which":[173],"provides":[174],"information":[175],"its":[177],"underlying":[178],"mechanism.":[179],"Applied":[180],"significantly":[187],"outperforms":[188],"existing":[189],"methods":[190],"both":[192],"precision":[193],"sensitivity.":[195],"AVAILABILITY":[196],"AND":[197],"IMPLEMENTATION:":[198],"written":[201],"Python":[203],"available":[205,215],"https://github.com/UdeM-LBIT/CoreTracker.":[207],"CONTACT:":[208],"mabrouk@iro.umontreal.ca.":[209],"SUPPLEMENTARY":[210],"INFORMATION:":[211],"Supplementary":[212],"data":[213],"Bioinformatics":[217],"online.":[218]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}