{"id":"https://openalex.org/W2132105963","doi":"https://doi.org/10.1093/bioinformatics/btw410","title":"Network-based pathway enrichment analysis with incomplete network information","display_name":"Network-based pathway enrichment analysis with incomplete network information","publication_year":2016,"publication_date":"2016-06-29","ids":{"openalex":"https://openalex.org/W2132105963","doi":"https://doi.org/10.1093/bioinformatics/btw410","mag":"2132105963","pmid":"https://pubmed.ncbi.nlm.nih.gov/27357170"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btw410","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btw410","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/32/20/3165/25416785/btw410.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/32/20/3165/25416785/btw410.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101881919","display_name":"Jing Ma","orcid":"https://orcid.org/0000-0001-6294-227X"},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jing Ma","raw_affiliation_strings":["1 Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, PA 19104, USA,"],"affiliations":[{"raw_affiliation_string":"1 Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, PA 19104, USA,","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060606663","display_name":"Ali Shojaie","orcid":"https://orcid.org/0000-0001-8846-3533"},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ali Shojaie","raw_affiliation_strings":["2 Department of Biostatistics, University of Washington, Seattle, WA 98915, USA"],"affiliations":[{"raw_affiliation_string":"2 Department of Biostatistics, University of Washington, Seattle, WA 98915, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017220650","display_name":"George Michailidis","orcid":"https://orcid.org/0000-0002-3676-1739"},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George Michailidis","raw_affiliation_strings":["3 Department of Statistics, University of Florida, Gainesville, FL 32611, USA"],"affiliations":[{"raw_affiliation_string":"3 Department of Statistics, University of Florida, Gainesville, FL 32611, USA","institution_ids":["https://openalex.org/I33213144"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5101881919"],"corresponding_institution_ids":["https://openalex.org/I79576946"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":4.1834,"has_fulltext":false,"cited_by_count":59,"citation_normalized_percentile":{"value":0.94186177,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"32","issue":"20","first_page":"3165","last_page":"3174"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/estimator","display_name":"Estimator","score":0.6936265826225281},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6680803298950195},{"id":"https://openalex.org/keywords/biological-network","display_name":"Biological network","score":0.5779304504394531},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.5630699396133423},{"id":"https://openalex.org/keywords/network-analysis","display_name":"Network analysis","score":0.550722062587738},{"id":"https://openalex.org/keywords/network-topology","display_name":"Network topology","score":0.5488269925117493},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4924207925796509},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.458977609872818},{"id":"https://openalex.org/keywords/biological-pathway","display_name":"Biological pathway","score":0.42580366134643555},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.20031023025512695},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.17235934734344482},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1447353959083557},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.08797010779380798},{"id":"https://openalex.org/keywords/computer-network","display_name":"Computer network","score":0.08480089902877808},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.08304822444915771}],"concepts":[{"id":"https://openalex.org/C185429906","wikidata":"https://www.wikidata.org/wiki/Q1130160","display_name":"Estimator","level":2,"score":0.6936265826225281},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6680803298950195},{"id":"https://openalex.org/C28225019","wikidata":"https://www.wikidata.org/wiki/Q4915005","display_name":"Biological network","level":2,"score":0.5779304504394531},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.5630699396133423},{"id":"https://openalex.org/C32946077","wikidata":"https://www.wikidata.org/wiki/Q618079","display_name":"Network analysis","level":2,"score":0.550722062587738},{"id":"https://openalex.org/C199845137","wikidata":"https://www.wikidata.org/wiki/Q145490","display_name":"Network topology","level":2,"score":0.5488269925117493},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4924207925796509},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.458977609872818},{"id":"https://openalex.org/C9927688","wikidata":"https://www.wikidata.org/wiki/Q4915012","display_name":"Biological pathway","level":4,"score":0.42580366134643555},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20031023025512695},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.17235934734344482},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1447353959083557},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08797010779380798},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.08480089902877808},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08304822444915771},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D002450","descriptor_name":"Cell Communication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002450","descriptor_name":"Cell Communication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002450","descriptor_name":"Cell Communication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002450","descriptor_name":"Cell Communication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060066","descriptor_name":"Protein Interaction Maps","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060066","descriptor_name":"Protein Interaction Maps","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060066","descriptor_name":"Protein Interaction Maps","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060066","descriptor_name":"Protein Interaction Maps","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1093/bioinformatics/btw410","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btw410","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/32/20/3165/25416785/btw410.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:27357170","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27357170","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.762.7297","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.762.7297","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://arxiv.org/pdf/1411.7919.pdf","raw_type":"text"},{"id":"pmh:oai:europepmc.org:5027268","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5939912","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:open-archive.highwire.org:bioinfo:32/20/3165","is_oa":false,"landing_page_url":"http://bioinformatics.oxfordjournals.org/cgi/content/short/32/20/3165","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btw410","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btw410","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/32/20/3165/25416785/btw410.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Partnerships for the goals","score":0.4300000071525574,"id":"https://metadata.un.org/sdg/17"}],"awards":[{"id":"https://openalex.org/G2879420693","display_name":null,"funder_award_id":"1K01HL124050-01A1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2132105963.pdf","grobid_xml":"https://content.openalex.org/works/W2132105963.grobid-xml"},"referenced_works_count":52,"referenced_works":["https://openalex.org/W229097380","https://openalex.org/W587005977","https://openalex.org/W1596515083","https://openalex.org/W1967964480","https://openalex.org/W1973508741","https://openalex.org/W1974105260","https://openalex.org/W1975387345","https://openalex.org/W1989108446","https://openalex.org/W2006410094","https://openalex.org/W2010824638","https://openalex.org/W2020859582","https://openalex.org/W2028601867","https://openalex.org/W2038711071","https://openalex.org/W2044702943","https://openalex.org/W2048158327","https://openalex.org/W2054892633","https://openalex.org/W2063851753","https://openalex.org/W2079301619","https://openalex.org/W2086905232","https://openalex.org/W2091082435","https://openalex.org/W2093034235","https://openalex.org/W2096283457","https://openalex.org/W2100980426","https://openalex.org/W2101103478","https://openalex.org/W2110065044","https://openalex.org/W2116581043","https://openalex.org/W2118640842","https://openalex.org/W2120672356","https://openalex.org/W2122863959","https://openalex.org/W2130410032","https://openalex.org/W2132555912","https://openalex.org/W2138153486","https://openalex.org/W2143076232","https://openalex.org/W2147566730","https://openalex.org/W2158217645","https://openalex.org/W2159482845","https://openalex.org/W2296319761","https://openalex.org/W2320061406","https://openalex.org/W2560367415","https://openalex.org/W2611328865","https://openalex.org/W2798510847","https://openalex.org/W2950471994","https://openalex.org/W3098834468","https://openalex.org/W3099718522","https://openalex.org/W3106319742","https://openalex.org/W4238253035","https://openalex.org/W4242404314","https://openalex.org/W4250589301","https://openalex.org/W4294216483","https://openalex.org/W4388323202","https://openalex.org/W6608852248","https://openalex.org/W6678231584"],"related_works":["https://openalex.org/W2158714033","https://openalex.org/W4386628104","https://openalex.org/W2163262592","https://openalex.org/W3213185671","https://openalex.org/W4206945140","https://openalex.org/W2509687359","https://openalex.org/W4212865750","https://openalex.org/W2362023034","https://openalex.org/W78967844","https://openalex.org/W2952963846"],"abstract_inverted_index":{"jinma@upenn.eduSupplementary":[0],"information:":[1],"Supplementary":[2],"data":[3],"are":[4],"available":[5],"at":[6],"Bioinformatics":[7],"online.":[8]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":1}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}