{"id":"https://openalex.org/W2439879183","doi":"https://doi.org/10.1093/bioinformatics/btw282","title":"Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks","display_name":"Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks","publication_year":2016,"publication_date":"2016-06-11","ids":{"openalex":"https://openalex.org/W2439879183","doi":"https://doi.org/10.1093/bioinformatics/btw282","mag":"2439879183","pmid":"https://pubmed.ncbi.nlm.nih.gov/27307606"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btw282","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btw282","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/32/12/i101/17130631/btw282.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/32/12/i101/17130631/btw282.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030539003","display_name":"Benjamin S. Glicksberg","orcid":"https://orcid.org/0000-0003-4515-8090"},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["GB","US"],"is_corresponding":true,"raw_author_name":"Benjamin S. Glicksberg","raw_affiliation_strings":["1 Department of Genetics and Genomic Sciences","2 Icahn Institute for Genomics and Multiscale Biology","3 Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Genetics and Genomic Sciences","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"2 Icahn Institute for Genomics and Multiscale Biology","institution_ids":["https://openalex.org/I4210151791"]},{"raw_affiliation_string":"3 Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100361005","display_name":"Li Li","orcid":"https://orcid.org/0000-0001-6746-4297"},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Li Li","raw_affiliation_strings":["1 Department of Genetics and Genomic Sciences","2 Icahn Institute for Genomics and Multiscale Biology","3 Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Genetics and Genomic Sciences","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"2 Icahn Institute for Genomics and Multiscale Biology","institution_ids":["https://openalex.org/I4210151791"]},{"raw_affiliation_string":"3 Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032864572","display_name":"Marcus A. Badgeley","orcid":"https://orcid.org/0000-0001-8064-9050"},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Marcus A. Badgeley","raw_affiliation_strings":["1 Department of Genetics and Genomic Sciences","2 Icahn Institute for Genomics and Multiscale Biology","3 Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Genetics and Genomic Sciences","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"2 Icahn Institute for Genomics and Multiscale Biology","institution_ids":["https://openalex.org/I4210151791"]},{"raw_affiliation_string":"3 Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016416266","display_name":"Khader Shameer","orcid":"https://orcid.org/0000-0002-9982-1911"},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Khader Shameer","raw_affiliation_strings":["1 Department of Genetics and Genomic Sciences","2 Icahn Institute for Genomics and Multiscale Biology","3 Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Genetics and Genomic Sciences","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"2 Icahn Institute for Genomics and Multiscale Biology","institution_ids":["https://openalex.org/I4210151791"]},{"raw_affiliation_string":"3 Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059897389","display_name":"Roman Kosoy","orcid":"https://orcid.org/0000-0002-3080-7900"},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Roman Kosoy","raw_affiliation_strings":["1 Department of Genetics and Genomic Sciences","2 Icahn Institute for Genomics and Multiscale Biology","3 Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Genetics and Genomic Sciences","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"2 Icahn Institute for Genomics and Multiscale Biology","institution_ids":["https://openalex.org/I4210151791"]},{"raw_affiliation_string":"3 Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077594919","display_name":"Noam D. Beckmann","orcid":"https://orcid.org/0000-0002-4258-1574"},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Noam D. Beckmann","raw_affiliation_strings":["1 Department of Genetics and Genomic Sciences","2 Icahn Institute for Genomics and Multiscale Biology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Genetics and Genomic Sciences","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"2 Icahn Institute for Genomics and Multiscale Biology","institution_ids":["https://openalex.org/I4210151791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019610421","display_name":"Nam Pho","orcid":"https://orcid.org/0000-0002-0456-2532"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nam Pho","raw_affiliation_strings":["4 Department of Biomedical Informatics, Harvard Medical School, Boston, 02115\u2009MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4 Department of Biomedical Informatics, Harvard Medical School, Boston, 02115\u2009MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034893893","display_name":"J\u00f6rg Hakenberg","orcid":"https://orcid.org/0000-0001-8781-7766"},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"J\u00f6rg Hakenberg","raw_affiliation_strings":["1 Department of Genetics and Genomic Sciences","2 Icahn Institute for Genomics and Multiscale Biology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Genetics and Genomic Sciences","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"2 Icahn Institute for Genomics and Multiscale Biology","institution_ids":["https://openalex.org/I4210151791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100762315","display_name":"Meng Ma","orcid":"https://orcid.org/0000-0002-0212-298X"},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Meng Ma","raw_affiliation_strings":["1 Department of Genetics and Genomic Sciences","2 Icahn Institute for Genomics and Multiscale Biology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Genetics and Genomic Sciences","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"2 Icahn Institute for Genomics and Multiscale Biology","institution_ids":["https://openalex.org/I4210151791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106731347","display_name":"Kristin L. Ayers","orcid":"https://orcid.org/0000-0002-4984-5229"},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Kristin L. Ayers","raw_affiliation_strings":["1 Department of Genetics and Genomic Sciences","2 Icahn Institute for Genomics and Multiscale Biology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Genetics and Genomic Sciences","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"2 Icahn Institute for Genomics and Multiscale Biology","institution_ids":["https://openalex.org/I4210151791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046862823","display_name":"Gabriel E. Hoffman","orcid":"https://orcid.org/0000-0002-0957-0224"},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Gabriel E. Hoffman","raw_affiliation_strings":["1 Department of Genetics and Genomic Sciences","2 Icahn Institute for Genomics and Multiscale Biology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Genetics and Genomic Sciences","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"2 Icahn Institute for Genomics and Multiscale Biology","institution_ids":["https://openalex.org/I4210151791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057258842","display_name":"Shuyu Dan Li","orcid":"https://orcid.org/0000-0002-1163-8339"},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Shuyu Dan Li","raw_affiliation_strings":["1 Department of Genetics and Genomic Sciences","2 Icahn Institute for Genomics and Multiscale Biology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Genetics and Genomic Sciences","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"2 Icahn Institute for Genomics and Multiscale Biology","institution_ids":["https://openalex.org/I4210151791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071946434","display_name":"Eric E. Schadt","orcid":"https://orcid.org/0000-0002-7892-8808"},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Eric E. Schadt","raw_affiliation_strings":["1 Department of Genetics and Genomic Sciences","2 Icahn Institute for Genomics and Multiscale Biology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Genetics and Genomic Sciences","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"2 Icahn Institute for Genomics and Multiscale Biology","institution_ids":["https://openalex.org/I4210151791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100638285","display_name":"Chirag J. Patel","orcid":"https://orcid.org/0000-0002-8756-8525"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chirag J. Patel","raw_affiliation_strings":["4 Department of Biomedical Informatics, Harvard Medical School, Boston, 02115\u2009MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4 Department of Biomedical Informatics, Harvard Medical School, Boston, 02115\u2009MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100419008","display_name":"Rong Chen","orcid":"https://orcid.org/0000-0002-0552-7616"},"institutions":[{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Rong Chen","raw_affiliation_strings":["1 Department of Genetics and Genomic Sciences","2 Icahn Institute for Genomics and Multiscale Biology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Genetics and Genomic Sciences","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"2 Icahn Institute for Genomics and Multiscale Biology","institution_ids":["https://openalex.org/I4210151791"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043599202","display_name":"Joel T. Dudley","orcid":"https://orcid.org/0000-0002-7036-6492"},"institutions":[{"id":"https://openalex.org/I4210132262","display_name":"Population Council","ror":"https://ror.org/03zjj0p70","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210132262"]},{"id":"https://openalex.org/I4210147155","display_name":"Pediatrics and Genetics","ror":"https://ror.org/03t432d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147155"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Joel T. Dudley","raw_affiliation_strings":["1 Department of Genetics and Genomic Sciences","2 Icahn Institute for Genomics and Multiscale Biology","3 Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA","5 Department of Population Health Science and Policy, New York City, NY 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Genetics and Genomic Sciences","institution_ids":["https://openalex.org/I4210147155"]},{"raw_affiliation_string":"2 Icahn Institute for Genomics and Multiscale Biology","institution_ids":["https://openalex.org/I4210151791"]},{"raw_affiliation_string":"3 Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"5 Department of Population Health Science and Policy, New York City, NY 10029, USA","institution_ids":["https://openalex.org/I4210132262"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":16,"corresponding_author_ids":["https://openalex.org/A5030539003"],"corresponding_institution_ids":["https://openalex.org/I4210147155","https://openalex.org/I4210151791","https://openalex.org/I98704320"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":5.6277,"has_fulltext":true,"cited_by_count":48,"citation_normalized_percentile":{"value":0.95774036,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"32","issue":"12","first_page":"i101","last_page":"i110"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.45669999718666077,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.45669999718666077,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14393","display_name":"Health, Environment, Cognitive Aging","score":0.1648000031709671,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13283","display_name":"Mental Health Research Topics","score":0.051899999380111694,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/race","display_name":"Race (biology)","score":0.7119855880737305},{"id":"https://openalex.org/keywords/scale","display_name":"Scale (ratio)","score":0.6092422008514404},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.5200647711753845},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.4554252028465271},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.45467787981033325},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.4360229969024658},{"id":"https://openalex.org/keywords/medical-record","display_name":"Medical record","score":0.4251832962036133},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.36343860626220703},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.25848883390426636},{"id":"https://openalex.org/keywords/geography","display_name":"Geography","score":0.2546573877334595},{"id":"https://openalex.org/keywords/cartography","display_name":"Cartography","score":0.22485262155532837},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.21985265612602234},{"id":"https://openalex.org/keywords/environmental-health","display_name":"Environmental health","score":0.19887614250183105},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.13956615328788757},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.09743702411651611}],"concepts":[{"id":"https://openalex.org/C76509639","wikidata":"https://www.wikidata.org/wiki/Q918036","display_name":"Race (biology)","level":2,"score":0.7119855880737305},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.6092422008514404},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5200647711753845},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.4554252028465271},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.45467787981033325},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4360229969024658},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.4251832962036133},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.36343860626220703},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.25848883390426636},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.2546573877334595},{"id":"https://openalex.org/C58640448","wikidata":"https://www.wikidata.org/wiki/Q42515","display_name":"Cartography","level":1,"score":0.22485262155532837},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21985265612602234},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.19887614250183105},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.13956615328788757},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09743702411651611},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001741","descriptor_name":"Black or African American","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001741","descriptor_name":"Black or African American","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001741","descriptor_name":"Black or African American","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006630","descriptor_name":"Hispanic or Latino","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006630","descriptor_name":"Hispanic or Latino","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006630","descriptor_name":"Hispanic or Latino","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044465","descriptor_name":"White People","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044465","descriptor_name":"White People","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044465","descriptor_name":"White People","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1093/bioinformatics/btw282","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btw282","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/32/12/i101/17130631/btw282.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:27307606","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27307606","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:dash.harvard.edu:1/27662034","is_oa":true,"landing_page_url":"http://nrs.harvard.edu/urn-3:HUL.InstRepos:27662034","pdf_url":null,"source":{"id":"https://openalex.org/S4306401540","display_name":"Digital Access to Scholarship at Harvard (DASH) (Harvard University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I136199984","host_organization_name":"Harvard University","host_organization_lineage":["https://openalex.org/I136199984"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:oai:open-archive.highwire.org:bioinfo:32/12/i101","is_oa":false,"landing_page_url":"http://bioinformatics.oxfordjournals.org/cgi/content/short/32/12/i101","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"pmh:oai:pubmedcentral.nih.gov:4908366","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4908366","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btw282","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btw282","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/32/12/i101/17130631/btw282.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1052734129","display_name":null,"funder_award_id":"UL1TR000067","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G1389460797","display_name":null,"funder_award_id":"R01DK098242","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1788507866","display_name":null,"funder_award_id":"U54-CA189201-02","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G2390539897","display_name":null,"funder_award_id":"U54CA189201","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G3906510589","display_name":null,"funder_award_id":"R01DK098242","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G4720748319","display_name":null,"funder_award_id":"UL1TR000067","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5473470285","display_name":null,"funder_award_id":"U54-CA189201","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8518362915","display_name":null,"funder_award_id":"U54CA189201","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320309658","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77"},{"id":"https://openalex.org/F4320316438","display_name":"Georgia Clinical and Translational Science Alliance","ror":null},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"},{"id":"https://openalex.org/F4320337601","display_name":"Janssen Pharmaceuticals","ror":"https://ror.org/03qd7mz70"},{"id":"https://openalex.org/F4320338403","display_name":"Common Fund","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2439879183.pdf","grobid_xml":"https://content.openalex.org/works/W2439879183.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W62210441","https://openalex.org/W1597690493","https://openalex.org/W1628561756","https://openalex.org/W1826234378","https://openalex.org/W1839682376","https://openalex.org/W1964716329","https://openalex.org/W1970263201","https://openalex.org/W1973298132","https://openalex.org/W1974858693","https://openalex.org/W1979421770","https://openalex.org/W1981323832","https://openalex.org/W1984789788","https://openalex.org/W2004910511","https://openalex.org/W2010707723","https://openalex.org/W2028878367","https://openalex.org/W2032303051","https://openalex.org/W2041073071","https://openalex.org/W2043570667","https://openalex.org/W2049104279","https://openalex.org/W2059158127","https://openalex.org/W2062533676","https://openalex.org/W2068234084","https://openalex.org/W2083045667","https://openalex.org/W2087591041","https://openalex.org/W2113105800","https://openalex.org/W2115967402","https://openalex.org/W2117281960","https://openalex.org/W2120051475","https://openalex.org/W2128054164","https://openalex.org/W2138842039","https://openalex.org/W2152415104","https://openalex.org/W2152635811","https://openalex.org/W2155157373","https://openalex.org/W2157811055","https://openalex.org/W2159092541","https://openalex.org/W2159675211","https://openalex.org/W2163480486","https://openalex.org/W2165276227","https://openalex.org/W2192798466","https://openalex.org/W2271670697","https://openalex.org/W2309459004","https://openalex.org/W2313699046","https://openalex.org/W2330428186","https://openalex.org/W2338874172","https://openalex.org/W2410574058","https://openalex.org/W2417991027","https://openalex.org/W6635779058","https://openalex.org/W6657846422","https://openalex.org/W6693826158","https://openalex.org/W6699102673"],"related_works":["https://openalex.org/W2492471733","https://openalex.org/W3013012681","https://openalex.org/W2337668750","https://openalex.org/W2980238164","https://openalex.org/W2496505685","https://openalex.org/W61429289","https://openalex.org/W1718051419","https://openalex.org/W2495030604","https://openalex.org/W3210107878","https://openalex.org/W2221713143"],"abstract_inverted_index":{"MOTIVATION:":[0],"Underrepresentation":[1],"of":[2,16,62,66,82,96,134,194,214,231,242],"racial":[3,64],"groups":[4],"represents":[5],"an":[6,31],"important":[7,32],"challenge":[8,33],"and":[9,58,77,109,117,124,151,158,174,213,228,236,245],"major":[10],"gap":[11],"in":[12,130,144,209],"phenomics":[13,20],"research.":[14],"Most":[15],"the":[17,74,80,88,168,206,210,232],"current":[18],"human":[19],"research":[21],"is":[22,30,44,87],"based":[23],"primarily":[24],"on":[25,73],"European":[26],"populations;":[27],"hence":[28],"it":[29,36],"to":[34,37,45,91,186],"expand":[35],"consider":[38],"other":[39],"population":[40,133,188],"groups.":[41],"One":[42],"approach":[43],"utilize":[46],"data":[47,54,67,259],"from":[48,55],"EMR":[49],"databases":[50],"that":[51,204],"contain":[52],"patient":[53,246],"diverse":[56],"demographics":[57],"ancestries.":[59],"The":[60],"implications":[61],"this":[63],"underrepresentation":[65],"can":[68],"be":[69],"profound":[70],"regarding":[71],"effects":[72],"healthcare":[75],"delivery":[76],"actionability.":[78],"To":[79],"best":[81],"our":[83,85],"knowledge,":[84],"work":[86],"first":[89],"attempt":[90],"perform":[92],"comparative,":[93],"population-scale":[94],"analyses":[95],"disease":[97,127,145,153,182,220,233,243],"networks":[98,212],"across":[99],"three":[100],"different":[101],"populations,":[102],"namely":[103],"Caucasian":[104],"(EA),":[105],"African":[106],"American":[107],"(AA)":[108],"Hispanic/Latino":[110],"(HL).":[111],"RESULTS:":[112],"We":[113,161,178],"compared":[114],"susceptibility":[115],"profiles":[116],"temporal":[118,147],"connectivity":[119],"patterns":[120,222],"for":[121,167,172,176],"1988":[122],"diseases":[123,166,203],"37":[125],"282":[126],"pairs":[128],"represented":[129],"a":[131,225],"clinical":[132,216,250],"1":[135],"025":[136],"573":[137],"patients.":[138],"Accordingly,":[139],"we":[140,198],"revealed":[141],"appreciable":[142],"differences":[143],"susceptibility,":[146],"patterns,":[148],"network":[149],"structure":[150],"underlying":[152],"connections":[154],"between":[155],"EA,":[156],"AA":[157,173],"HL":[159],"populations.":[160],"found":[162],"2158":[163],"significantly":[164],"comorbid":[165],"EA":[169],"cohort,":[170],"3265":[171],"672":[175],"HL.":[177],"further":[179],"outlined":[180],"key":[181,201],"pair":[183],"associations":[184],"unique":[185],"each":[187],"as":[189,191],"well":[190],"categorical":[192],"enrichments":[193],"these":[195],"pairs.":[196],"Finally,":[197],"identified":[199],"51":[200],"'hub'":[202],"are":[205,260],"focal":[207],"points":[208],"race-centric":[211],"particular":[215],"importance.":[217],"Incorporating":[218],"race-specific":[219],"comorbidity":[221],"will":[223],"produce":[224],"more":[226,239],"accurate":[227],"complete":[229],"picture":[230],"landscape":[234],"overall":[235],"could":[237],"support":[238],"precise":[240],"understanding":[241],"relationships":[244],"management":[247],"towards":[248],"improved":[249],"outcomes.":[251],"CONTACTS:":[252],"rong.chen@mssm.edu":[253],"or":[254],"joel.dudley@mssm.edu":[255],"SUPPLEMENTARY":[256],"INFORMATION:":[257],"Supplementary":[258],"available":[261],"at":[262],"Bioinformatics":[263],"online.":[264]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2}],"updated_date":"2026-04-30T09:15:22.047038","created_date":"2025-10-10T00:00:00"}