{"id":"https://openalex.org/W2951764674","doi":"https://doi.org/10.1093/bioinformatics/btv715","title":"<i>destiny</i> : diffusion maps for large-scale single-cell data in R","display_name":"<i>destiny</i> : diffusion maps for large-scale single-cell data in R","publication_year":2015,"publication_date":"2015-12-14","ids":{"openalex":"https://openalex.org/W2951764674","doi":"https://doi.org/10.1093/bioinformatics/btv715","mag":"2951764674","pmid":"https://pubmed.ncbi.nlm.nih.gov/26668002"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btv715","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btv715","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053620470","display_name":"Philipp Angerer","orcid":"https://orcid.org/0000-0002-0369-2888"},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Philipp Angerer","raw_affiliation_strings":["1 Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Institute of Computational Biology, Ingolst\u00e4dter Landstr. 1, 85764 Neuherberg, Germany and"],"affiliations":[{"raw_affiliation_string":"1 Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Institute of Computational Biology, Ingolst\u00e4dter Landstr. 1, 85764 Neuherberg, Germany and","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001174105","display_name":"Laleh Haghverdi","orcid":"https://orcid.org/0000-0001-9280-9170"},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Laleh Haghverdi","raw_affiliation_strings":["1 Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Institute of Computational Biology, Ingolst\u00e4dter Landstr. 1, 85764 Neuherberg, Germany and"],"affiliations":[{"raw_affiliation_string":"1 Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Institute of Computational Biology, Ingolst\u00e4dter Landstr. 1, 85764 Neuherberg, Germany and","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013441539","display_name":"Maren B\u00fcttner","orcid":"https://orcid.org/0000-0002-6189-3792"},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Maren B\u00fcttner","raw_affiliation_strings":["1 Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Institute of Computational Biology, Ingolst\u00e4dter Landstr. 1, 85764 Neuherberg, Germany and"],"affiliations":[{"raw_affiliation_string":"1 Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Institute of Computational Biology, Ingolst\u00e4dter Landstr. 1, 85764 Neuherberg, Germany and","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083128670","display_name":"Fabian J. Theis","orcid":"https://orcid.org/0000-0002-2419-1943"},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Fabian J. Theis","raw_affiliation_strings":["1 Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Institute of Computational Biology, Ingolst\u00e4dter Landstr. 1, 85764 Neuherberg, Germany and","2 Technische Universit\u00e4t M\u00fcnchen, Center for Mathematics, Chair of Mathematical Modeling of Biological Systems, Boltzmannstr. 3, 85748 Garching, Germany"],"affiliations":[{"raw_affiliation_string":"1 Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Institute of Computational Biology, Ingolst\u00e4dter Landstr. 1, 85764 Neuherberg, Germany and","institution_ids":["https://openalex.org/I3018134672"]},{"raw_affiliation_string":"2 Technische Universit\u00e4t M\u00fcnchen, Center for Mathematics, Chair of Mathematical Modeling of Biological Systems, Boltzmannstr. 3, 85748 Garching, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046721596","display_name":"Carsten Marr","orcid":"https://orcid.org/0000-0003-2154-4552"},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Carsten Marr","raw_affiliation_strings":["1 Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Institute of Computational Biology, Ingolst\u00e4dter Landstr. 1, 85764 Neuherberg, Germany and"],"affiliations":[{"raw_affiliation_string":"1 Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Institute of Computational Biology, Ingolst\u00e4dter Landstr. 1, 85764 Neuherberg, Germany and","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021809355","display_name":"Florian Buettner","orcid":"https://orcid.org/0000-0001-5587-6761"},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Florian Buettner","raw_affiliation_strings":["1 Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Institute of Computational Biology, Ingolst\u00e4dter Landstr. 1, 85764 Neuherberg, Germany and"],"affiliations":[{"raw_affiliation_string":"1 Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Institute of Computational Biology, Ingolst\u00e4dter Landstr. 1, 85764 Neuherberg, Germany and","institution_ids":["https://openalex.org/I3018134672"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5021809355","https://openalex.org/A5046721596"],"corresponding_institution_ids":["https://openalex.org/I3018134672"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":15.6962,"has_fulltext":false,"cited_by_count":686,"citation_normalized_percentile":{"value":0.99421158,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"32","issue":"8","first_page":"1241","last_page":"1243"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11829","display_name":"Mathematical Biology Tumor Growth","score":0.9891999959945679,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9850999712944031,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/destiny","display_name":"Destiny (ISS module)","score":0.7900223135948181},{"id":"https://openalex.org/keywords/scale","display_name":"Scale (ratio)","score":0.6608474850654602},{"id":"https://openalex.org/keywords/diffusion","display_name":"Diffusion","score":0.5988115072250366},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5258287191390991},{"id":"https://openalex.org/keywords/cartography","display_name":"Cartography","score":0.146436870098114},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.12290707230567932},{"id":"https://openalex.org/keywords/geography","display_name":"Geography","score":0.11047044396400452}],"concepts":[{"id":"https://openalex.org/C44761211","wikidata":"https://www.wikidata.org/wiki/Q752841","display_name":"Destiny (ISS module)","level":2,"score":0.7900223135948181},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.6608474850654602},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.5988115072250366},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5258287191390991},{"id":"https://openalex.org/C58640448","wikidata":"https://www.wikidata.org/wiki/Q42515","display_name":"Cartography","level":1,"score":0.146436870098114},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.12290707230567932},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.11047044396400452},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C1276947","wikidata":"https://www.wikidata.org/wiki/Q333","display_name":"Astronomy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btv715","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btv715","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:26668002","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26668002","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:open-archive.highwire.org:bioinfo:32/8/1241","is_oa":false,"landing_page_url":"http://bioinformatics.oxfordjournals.org/cgi/content/short/32/8/1241","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G7544798330","display_name":null,"funder_award_id":"MR/M01536X/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1987236926","https://openalex.org/W1995424704","https://openalex.org/W2006554089","https://openalex.org/W2043345494","https://openalex.org/W2099236226","https://openalex.org/W2128120736","https://openalex.org/W4399548053"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2388760255","https://openalex.org/W2384421418","https://openalex.org/W2365251293","https://openalex.org/W2516216725","https://openalex.org/W2500832467","https://openalex.org/W2353246513","https://openalex.org/W3134162127"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":22},{"year":2025,"cited_by_count":84},{"year":2024,"cited_by_count":70},{"year":2023,"cited_by_count":81},{"year":2022,"cited_by_count":86},{"year":2021,"cited_by_count":89},{"year":2020,"cited_by_count":88},{"year":2019,"cited_by_count":64},{"year":2018,"cited_by_count":46},{"year":2017,"cited_by_count":39},{"year":2016,"cited_by_count":17}],"updated_date":"2026-04-18T07:56:08.524223","created_date":"2019-06-27T00:00:00"}