{"id":"https://openalex.org/W2262829055","doi":"https://doi.org/10.1093/bioinformatics/btv581","title":"FALCON@home: a high-throughput protein structure prediction server based on remote homologue recognition","display_name":"FALCON@home: a high-throughput protein structure prediction server based on remote homologue recognition","publication_year":2015,"publication_date":"2015-10-10","ids":{"openalex":"https://openalex.org/W2262829055","doi":"https://doi.org/10.1093/bioinformatics/btv581","mag":"2262829055","pmid":"https://pubmed.ncbi.nlm.nih.gov/26454278"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btv581","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btv581","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/32/3/462/49016835/bioinformatics_32_3_462.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/32/3/462/49016835/bioinformatics_32_3_462.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100406989","display_name":"Chao Wang","orcid":"https://orcid.org/0000-0002-4649-3176"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chao Wang","raw_affiliation_strings":["1 Key Lab of Intelligent Information Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China,","2 University of Chinese Academy of Sciences, Beijing, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Key Lab of Intelligent Information Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China,","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]},{"raw_affiliation_string":"2 University of Chinese Academy of Sciences, Beijing, China,","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060273621","display_name":"Haicang Zhang","orcid":"https://orcid.org/0000-0001-6268-4258"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haicang Zhang","raw_affiliation_strings":["1 Key Lab of Intelligent Information Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China,","2 University of Chinese Academy of Sciences, Beijing, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Key Lab of Intelligent Information Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China,","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]},{"raw_affiliation_string":"2 University of Chinese Academy of Sciences, Beijing, China,","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021041719","display_name":"Wei\u2010Mou Zheng","orcid":"https://orcid.org/0000-0001-6546-2917"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210125404","display_name":"Institute of Theoretical Physics","ror":"https://ror.org/02xtbq882","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210125404"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei-Mou Zheng","raw_affiliation_strings":["3 Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3 Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing, China,","institution_ids":["https://openalex.org/I4210125404","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082428303","display_name":"Dong Xu","orcid":"https://orcid.org/0000-0002-4809-0514"},"institutions":[{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dong Xu","raw_affiliation_strings":["4 Department of Computer Science and Christopher S. Bond Life Sciences Center, University of Missouri, MO 65211, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4 Department of Computer Science and Christopher S. Bond Life Sciences Center, University of Missouri, MO 65211, USA,","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053196390","display_name":"Jianwei Zhu","orcid":"https://orcid.org/0000-0002-8272-9190"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianwei Zhu","raw_affiliation_strings":["1 Key Lab of Intelligent Information Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Key Lab of Intelligent Information Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China,","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100382568","display_name":"Bing Wang","orcid":"https://orcid.org/0000-0003-4945-7725"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bing Wang","raw_affiliation_strings":["1 Key Lab of Intelligent Information Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Key Lab of Intelligent Information Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China,","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076346443","display_name":"Kang Ning","orcid":"https://orcid.org/0000-0003-3325-5387"},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kang Ning","raw_affiliation_strings":["5 College of Life Science, Huazhong University of Science and Technology, Wuhan, China and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"5 College of Life Science, Huazhong University of Science and Technology, Wuhan, China and","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108903761","display_name":"Shiwei Sun","orcid":"https://orcid.org/0000-0002-0351-3720"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shiwei Sun","raw_affiliation_strings":["1 Key Lab of Intelligent Information Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Key Lab of Intelligent Information Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China,","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083428910","display_name":"Shuai Cheng Li","orcid":"https://orcid.org/0000-0001-6246-6349"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":true,"raw_author_name":"Shuai Cheng Li","raw_affiliation_strings":["6 Department of Computer Science, City University of Hong Kong, Kowloon, Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"6 Department of Computer Science, City University of Hong Kong, Kowloon, Hong Kong","institution_ids":["https://openalex.org/I168719708"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076729236","display_name":"Dongbo Bu","orcid":"https://orcid.org/0000-0003-4119-4238"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Dongbo Bu","raw_affiliation_strings":["1 Key Lab of Intelligent Information Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Key Lab of Intelligent Information Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China,","institution_ids":["https://openalex.org/I4210090176","https://openalex.org/I19820366"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5076729236","https://openalex.org/A5083428910"],"corresponding_institution_ids":["https://openalex.org/I168719708","https://openalex.org/I19820366","https://openalex.org/I4210090176"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":2.2169,"has_fulltext":true,"cited_by_count":43,"citation_normalized_percentile":{"value":0.88283175,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"32","issue":"3","first_page":"462","last_page":"464"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.44209998846054077,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.44209998846054077,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.41929998993873596,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.029600000008940697,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/threading","display_name":"Threading (protein sequence)","score":0.7030633091926575},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6697720289230347},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.49861669540405273},{"id":"https://openalex.org/keywords/falcon","display_name":"Falcon","score":0.4614694118499756},{"id":"https://openalex.org/keywords/uniprot","display_name":"UniProt","score":0.41350698471069336},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.34271568059921265},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.32464906573295593},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.21578338742256165},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.11510816216468811},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.10539308190345764}],"concepts":[{"id":"https://openalex.org/C200307862","wikidata":"https://www.wikidata.org/wiki/Q7797175","display_name":"Threading (protein sequence)","level":3,"score":0.7030633091926575},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6697720289230347},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.49861669540405273},{"id":"https://openalex.org/C2775845381","wikidata":"https://www.wikidata.org/wiki/Q43489","display_name":"Falcon","level":2,"score":0.4614694118499756},{"id":"https://openalex.org/C202264299","wikidata":"https://www.wikidata.org/wiki/Q905695","display_name":"UniProt","level":3,"score":0.41350698471069336},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.34271568059921265},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.32464906573295593},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21578338742256165},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11510816216468811},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10539308190345764},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057166","descriptor_name":"High-Throughput Screening Assays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057166","descriptor_name":"High-Throughput Screening Assays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057166","descriptor_name":"High-Throughput Screening Assays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btv581","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btv581","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/32/3/462/49016835/bioinformatics_32_3_462.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:26454278","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26454278","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:europepmc.org:4145648","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4804767","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:open-archive.highwire.org:bioinfo:32/3/462","is_oa":false,"landing_page_url":"http://bioinformatics.oxfordjournals.org/cgi/content/short/32/3/462","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btv581","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btv581","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/32/3/462/49016835/bioinformatics_32_3_462.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Industry, innovation and infrastructure","score":0.6499999761581421,"id":"https://metadata.un.org/sdg/9"}],"awards":[{"id":"https://openalex.org/G130909266","display_name":null,"funder_award_id":"30870572","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1434303207","display_name":null,"funder_award_id":"11175224","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1617341002","display_name":null,"funder_award_id":"11121403","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2564083438","display_name":null,"funder_award_id":"R33 GM078601","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2660623004","display_name":null,"funder_award_id":"R01-GM100701","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G3888631583","display_name":"\u86cb\u767d\u8d28\u7ed3\u6784\u6a21\u4f53\u8bc6\u522b\u53ca\u7ed3\u6784\u9884\u6d4b\u7b97\u6cd5\u7814\u7a76","funder_award_id":"61272318","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5987157409","display_name":null,"funder_award_id":"R01 GM100701","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G636961877","display_name":null,"funder_award_id":"61303161","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6594049289","display_name":null,"funder_award_id":"R21/R33-GM078601","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G7814778640","display_name":null,"funder_award_id":"31270834","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G795020757","display_name":null,"funder_award_id":"2012CB316502","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2262829055.pdf","grobid_xml":"https://content.openalex.org/works/W2262829055.grobid-xml"},"referenced_works_count":9,"referenced_works":["https://openalex.org/W1987134040","https://openalex.org/W2043304335","https://openalex.org/W2146628513","https://openalex.org/W2152811165","https://openalex.org/W2160672912","https://openalex.org/W2246807311","https://openalex.org/W2253761889","https://openalex.org/W6691062548","https://openalex.org/W6692079160"],"related_works":["https://openalex.org/W1741740882","https://openalex.org/W2050330741","https://openalex.org/W2253761889","https://openalex.org/W2123053169","https://openalex.org/W2181585194","https://openalex.org/W3149404221","https://openalex.org/W1493412556","https://openalex.org/W2111643578","https://openalex.org/W2802527233","https://openalex.org/W1504467230"],"abstract_inverted_index":{"SUMMARY:":[0],"The":[1,71,98],"protein":[2,62,123,192,226,229],"structure":[3,45,63],"prediction":[4,46,52,64,198],"approaches":[5],"can":[6],"be":[7],"categorized":[8],"into":[9],"template-based":[10,205],"modeling":[11,14,206],"(including":[12],"homology":[13],"and":[15,17,118,228],"threading)":[16],"free":[18],"modeling.":[19],"However,":[20],"the":[21,43,78,130,137,153,188,196,201,204,211,222],"existing":[22],"threading":[23,107],"tools":[24],"perform":[25],"poorly":[26],"on":[27,67,77],"remote":[28,36,68,86,146],"homologous":[29,37,87],"proteins.":[30],"Thus,":[31,109],"improving":[32,145],"fold":[33],"recognition":[34],"for":[35,85],"proteins":[38,184,217],"remains":[39],"a":[40,61,81,121,175],"challenge.":[41],"Besides,":[42],"proteome-wide":[44],"poses":[47],"another":[48],"challenge":[49],"of":[50,73,90,157,181,191,213],"increasing":[51],"throughput.":[53],"In":[54,187],"this":[55],"study,":[56],"we":[57],"presented":[58],"FALCON@home":[59,74,110,151,173,235],"as":[60,177,179],"server":[65],"focusing":[66],"homologue":[69,147],"identification.":[70,148],"design":[72],"is":[75,236],"based":[76],"observation":[79],"that":[80],"structural":[82,230],"template,":[83],"especially":[84],"proteins,":[88],"consists":[89],"conserved":[91,113,125],"regions":[92,101,114,126],"interweaved":[93],"with":[94,124],"highly":[95,99,142],"variable":[96,100,143],"regions.":[97],"lead":[102],"to":[103],"vague":[104,138],"alignments":[105,139],"in":[106,141,203],"approaches.":[108],"first":[111],"extracts":[112],"from":[115,168],"each":[116],"template":[117,132],"then":[119],"aligns":[120],"query":[122],"only":[127],"rather":[128],"than":[129],"full-length":[131],"directly.":[133],"This":[134],"helps":[135],"avoid":[136],"rooted":[140],"regions,":[144],"We":[149],"implemented":[150],"using":[152],"Berkeley":[154],"Open":[155],"Infrastructure":[156],"Network":[158],"Computing":[159],"(BOINC)":[160],"volunteer":[161,171],"computing":[162],"protocol.":[163],"With":[164],"computation":[165],"power":[166],"donated":[167],"over":[169,182],"20,000":[170],"CPUs,":[172],"shows":[174],"throughput":[176],"high":[178],"processing":[180],"1000":[183],"per":[185],"day.":[186],"Critical":[189],"Assessment":[190],"Structure":[193],"Prediction":[194],"(CASP11),":[195],"FALCON@home-based":[197],"was":[199],"ranked":[200],"12th":[202],"category.":[207],"As":[208],"an":[209],"application,":[210],"structures":[212],"880":[214],"mouse":[215],"mitochondria":[216],"were":[218],"predicted,":[219],"which":[220],"revealed":[221],"significant":[223],"correlation":[224],"between":[225],"half-lives":[227],"factors.":[231],"AVAILABILITY":[232],"AND":[233],"IMPLEMENTATION:":[234],"freely":[237],"available":[238,249],"at":[239,250],"http://protein.ict.ac.cn/FALCON/.":[240],"CONTACT:":[241],"shuaicli@cityu.edu.hk,":[242],"dbu@ict.ac.cn":[243],"SUPPLEMENTARY":[244],"INFORMATION:":[245],"Supplementary":[246],"data":[247],"are":[248],"Bioinformatics":[251],"online.":[252]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":6}],"updated_date":"2026-06-18T08:10:14.011955","created_date":"2025-10-10T00:00:00"}