{"id":"https://openalex.org/W2069424542","doi":"https://doi.org/10.1093/bioinformatics/btu772","title":"Bioimaging-based detection of mislocalized proteins in human cancers by semi-supervised learning","display_name":"Bioimaging-based detection of mislocalized proteins in human cancers by semi-supervised learning","publication_year":2014,"publication_date":"2014-11-19","ids":{"openalex":"https://openalex.org/W2069424542","doi":"https://doi.org/10.1093/bioinformatics/btu772","mag":"2069424542","pmid":"https://pubmed.ncbi.nlm.nih.gov/25414362"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btu772","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btu772","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/31/7/1111/17124315/btu772.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/31/7/1111/17124315/btu772.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100519536","display_name":"Ying-Ying Xu","orcid":"https://orcid.org/0000-0002-3185-811X"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Ying-Ying Xu","raw_affiliation_strings":["1 Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, and Key Laboratory of System Control and Information Processing, Ministry of Education of China, Shanghai 200240, China and 2Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, and Key Laboratory of System Control and Information Processing, Ministry of Education of China, Shanghai 200240, China and 2Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100614027","display_name":"Fan Yang","orcid":"https://orcid.org/0000-0001-5591-5919"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Fan Yang","raw_affiliation_strings":["1 Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, and Key Laboratory of System Control and Information Processing, Ministry of Education of China, Shanghai 200240, China and 2Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, and Key Laboratory of System Control and Information Processing, Ministry of Education of China, Shanghai 200240, China and 2Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100354659","display_name":"Yang Zhang","orcid":"https://orcid.org/0000-0002-2739-1916"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Yang Zhang","raw_affiliation_strings":["1 Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, and Key Laboratory of System Control and Information Processing, Ministry of Education of China, Shanghai 200240, China and 2Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, and Key Laboratory of System Control and Information Processing, Ministry of Education of China, Shanghai 200240, China and 2Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I27837315"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110270965","display_name":"Hong-Bin Shen","orcid":null},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["CN","US"],"is_corresponding":true,"raw_author_name":"Hong-Bin Shen","raw_affiliation_strings":["1 Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, and Key Laboratory of System Control and Information Processing, Ministry of Education of China, Shanghai 200240, China and 2Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, and Key Laboratory of System Control and Information Processing, Ministry of Education of China, Shanghai 200240, China and 2Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I27837315"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5110270965"],"corresponding_institution_ids":["https://openalex.org/I183067930","https://openalex.org/I27837315"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":3.2196,"has_fulltext":true,"cited_by_count":42,"citation_normalized_percentile":{"value":0.91418619,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"31","issue":"7","first_page":"1111","last_page":"1119"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.7897999882698059,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.7897999882698059,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.05869999900460243,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.04580000042915344,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6184949278831482},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5599490404129028},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4021451473236084},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.3576413691043854},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3217107355594635},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.19452163577079773}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6184949278831482},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5599490404129028},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4021451473236084},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.3576413691043854},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3217107355594635},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19452163577079773}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013347","descriptor_name":"Subcellular Fractions","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013347","descriptor_name":"Subcellular Fractions","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013347","descriptor_name":"Subcellular Fractions","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013347","descriptor_name":"Subcellular Fractions","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013347","descriptor_name":"Subcellular Fractions","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013347","descriptor_name":"Subcellular Fractions","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D022082","descriptor_name":"Cellular Structures","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D022082","descriptor_name":"Cellular Structures","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D022082","descriptor_name":"Cellular Structures","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btu772","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btu772","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/31/7/1111/17124315/btu772.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:25414362","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25414362","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:4382902","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4382902","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btu772","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btu772","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/31/7/1111/17124315/btu772.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1556211573","display_name":null,"funder_award_id":"GM-083107","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G1815782265","display_name":null,"funder_award_id":"R01GM083107","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2689756626","display_name":null,"funder_award_id":"R01 GM084222","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G3041388515","display_name":null,"funder_award_id":"91130033","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4365802360","display_name":null,"funder_award_id":"11JC1404800","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"},{"id":"https://openalex.org/G4399226039","display_name":null,"funder_award_id":"61222306","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5181285190","display_name":null,"funder_award_id":"201048","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5528838273","display_name":null,"funder_award_id":"11JC1404800","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7240326077","display_name":null,"funder_award_id":"61175024","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321885","display_name":"Science and Technology Commission of Shanghai Municipality","ror":"https://ror.org/03kt66j61"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2069424542.pdf","grobid_xml":"https://content.openalex.org/works/W2069424542.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W10980763","https://openalex.org/W92894758","https://openalex.org/W1596290664","https://openalex.org/W1598764398","https://openalex.org/W1907188384","https://openalex.org/W1943243678","https://openalex.org/W1969285483","https://openalex.org/W1970480709","https://openalex.org/W1975165783","https://openalex.org/W1985583020","https://openalex.org/W1995945562","https://openalex.org/W2012758140","https://openalex.org/W2017277794","https://openalex.org/W2025623420","https://openalex.org/W2034563706","https://openalex.org/W2037248589","https://openalex.org/W2050818286","https://openalex.org/W2063098774","https://openalex.org/W2080915318","https://openalex.org/W2081277484","https://openalex.org/W2111127373","https://openalex.org/W2111689752","https://openalex.org/W2114001234","https://openalex.org/W2118765266","https://openalex.org/W2123762916","https://openalex.org/W2130496575","https://openalex.org/W2133556223","https://openalex.org/W2144337984","https://openalex.org/W2152482858","https://openalex.org/W2153349010","https://openalex.org/W2154477800","https://openalex.org/W2154579105","https://openalex.org/W2155679637","https://openalex.org/W2156935079","https://openalex.org/W2257329432","https://openalex.org/W2797563284","https://openalex.org/W3151720684","https://openalex.org/W6603760306","https://openalex.org/W6635804413","https://openalex.org/W6639910096","https://openalex.org/W6640762217","https://openalex.org/W6676862110"],"related_works":["https://openalex.org/W2961085424","https://openalex.org/W2755342338","https://openalex.org/W2058170566","https://openalex.org/W4306674287","https://openalex.org/W2036807459","https://openalex.org/W2775347418","https://openalex.org/W1969923398","https://openalex.org/W2166024367","https://openalex.org/W2772917594","https://openalex.org/W3116076068"],"abstract_inverted_index":{"MOTIVATION:":[0],"There":[1],"is":[2,86],"a":[3,103,145],"long-term":[4],"interest":[5],"in":[6,32,48,95,114,134,172],"the":[7,55,80,89,131,139,151,166],"challenging":[8],"task":[9],"of":[10,19,36,42,57,70,83,154,177],"finding":[11],"translocated":[12],"and":[13,39,97,120,143,175,187],"mislocated":[14],"cancer":[15,64,111],"biomarker":[16,50],"proteins.":[17],"Bioimages":[18],"subcellular":[20,58,81,178],"protein":[21,43,90,112],"distribution":[22,91],"are":[23,189,197],"new":[24,104,167],"data":[25,113,186,196],"sources":[26],"which":[27],"have":[28],"attracted":[29],"much":[30],"attention":[31],"recent":[33],"years":[34],"because":[35,88],"their":[37],"intuitive":[38],"detailed":[40],"descriptions":[41],"distribution.":[44],"However,":[45],"automated":[46],"methods":[47],"large-scale":[49],"screening":[51],"suffer":[52],"significantly":[53],"from":[54,63],"lack":[56],"location":[59,179],"annotations":[60],"for":[61,148],"bioimages":[62],"tissues.":[65],"The":[66,185],"transfer":[67],"prediction":[68],"idea":[69],"applying":[71],"models":[72],"trained":[73],"on":[74],"normal":[75,96,135],"tissue":[76],"proteins":[77],"to":[78,128,137],"predict":[79],"locations":[82],"cancerous":[84,98],"ones":[85],"arbitrary":[87],"patterns":[92],"may":[93],"differ":[94],"states.":[99],"RESULTS:":[100],"We":[101],"developed":[102],"semi-supervised":[105,168],"protocol":[106,169],"that":[107,165],"can":[108,170],"use":[109,130],"unlabeled":[110],"model":[115],"construction":[116],"by":[117],"an":[118],"iterative":[119],"incremental":[121],"training":[122,140],"strategy.":[123],"Our":[124],"approach":[125],"enables":[126],"us":[127],"selectively":[129],"low-quality":[132],"images":[133,156],"states":[136],"expand":[138],"sample":[141],"space":[142],"provides":[144],"general":[146],"way":[147],"dealing":[149],"with":[150,159],"small":[152],"size":[153],"annotated":[155],"used":[157],"together":[158],"large":[160],"unannotated":[161],"ones.":[162],"Experiments":[163],"demonstrate":[164],"result":[171],"improved":[173],"accuracy":[174],"sensitivity":[176],"difference":[180],"detection.":[181],"AVAILABILITY":[182],"AND":[183],"IMPLEMENTATION:":[184],"code":[188],"available":[190,198],"at:":[191],"www.csbio.sjtu.edu.cn/bioinf/SemiBiomarker/.":[192],"SUPPLEMENTARY":[193],"INFORMATION:":[194],"Supplementary":[195],"at":[199],"Bioinformatics":[200],"online.":[201]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2}],"updated_date":"2026-08-01T09:00:35.917206","created_date":"2025-10-10T00:00:00"}