{"id":"https://openalex.org/W4241157363","doi":"https://doi.org/10.1093/bioinformatics/btu683","title":"Deconvolving tumor purity and ploidy by integrating copy number alterations and loss of heterozygosity","display_name":"Deconvolving tumor purity and ploidy by integrating copy number alterations and loss of heterozygosity","publication_year":2014,"publication_date":"2014-10-29","ids":{"openalex":"https://openalex.org/W4241157363","doi":"https://doi.org/10.1093/bioinformatics/btu683"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btu683","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btu683","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/31/4/618/49011112/bioinformatics_31_4_618.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/31/4/618/49011112/bioinformatics_31_4_618.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100421579","display_name":"Yi Li","orcid":"https://orcid.org/0000-0002-6134-3117"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yi Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5084618257","display_name":"Xiaohui Xie","orcid":"https://orcid.org/0000-0002-5479-6345"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiaohui Xie","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.1105,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.56419169,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"31","issue":"4","first_page":"618","last_page":"618"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.9573000073432922,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.9545000195503235,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/loss-of-heterozygosity","display_name":"Loss of heterozygosity","score":0.9305990934371948},{"id":"https://openalex.org/keywords/ploidy","display_name":"Ploidy","score":0.6765228509902954},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5360382795333862},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.36309581995010376},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3404560685157776},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.26073360443115234},{"id":"https://openalex.org/keywords/allele","display_name":"Allele","score":0.13682934641838074},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.07476156949996948}],"concepts":[{"id":"https://openalex.org/C143589142","wikidata":"https://www.wikidata.org/wiki/Q2617554","display_name":"Loss of heterozygosity","level":4,"score":0.9305990934371948},{"id":"https://openalex.org/C143191323","wikidata":"https://www.wikidata.org/wiki/Q118406","display_name":"Ploidy","level":3,"score":0.6765228509902954},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5360382795333862},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.36309581995010376},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3404560685157776},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.26073360443115234},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.13682934641838074},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07476156949996948}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btu683","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btu683","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/31/4/618/49011112/bioinformatics_31_4_618.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4402367","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4402367","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btu683","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btu683","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/31/4/618/49011112/bioinformatics_31_4_618.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.6000000238418579}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4241157363.pdf","grobid_xml":"https://content.openalex.org/works/W4241157363.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2082860237","https://openalex.org/W2353484916","https://openalex.org/W2119695867","https://openalex.org/W2414346359","https://openalex.org/W2001734836","https://openalex.org/W2007389278","https://openalex.org/W2414485083","https://openalex.org/W2130076355","https://openalex.org/W1990804418"],"abstract_inverted_index":{"Bioinformatics,":[0],"2014;30(15):2121\u20132129":[1],"doi:":[2],"10.1093/bioinformatics/btu174":[3],"The":[4,49,69],"acknowledgment":[5,18],"of":[6,78,83],"the":[7,45,53,75],"dbGaP":[8,41],"datasets":[9,61],"in":[10],"this":[11],"article":[12],"was":[13,71],"omitted":[14],"as":[15,20],"published.":[16],"Corrected":[17],"is":[19],"follows:":[21],"\u201cThe":[22],"authors":[23],"thank":[24],"J.":[25,30],"Biesinger,":[26],"D.":[27],"Quang":[28],"and":[29,58,65],"Wu":[31],"for":[32,43,52],"helpful":[33],"discussion.":[34],"They":[35],"would":[36],"also":[37],"like":[38],"to":[39],"acknowledge":[40],"repository":[42],"providing":[44],"cancer":[46,57,60],"sequencing":[47],"datasets.":[48],"accession":[50],"numbers":[51],"breast":[54],"cancer,":[55],"pancreatic":[56],"prostate":[59],"are":[62],"phs000369.v1.p1,":[63],"phs000516.v1.p1":[64],"phs000447.v1.p1,":[66],"respectively.":[67],"Funding:":[68],"work":[70],"partly":[72],"supported":[73],"by":[74],"National":[76],"Institute":[77],"Health":[79],"(grant":[80],"R01HG006870).":[81],"Conflict":[82],"interest:":[84],"none":[85],"declared.\u201d":[86]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1}],"updated_date":"2026-06-16T07:32:37.131356","created_date":"2025-10-10T00:00:00"}