{"id":"https://openalex.org/W2130311175","doi":"https://doi.org/10.1093/bioinformatics/btu671","title":"Novel function discovery with GeneMANIA: a new integrated resource for gene function prediction in <i>Escherichia coli</i>","display_name":"Novel function discovery with GeneMANIA: a new integrated resource for gene function prediction in <i>Escherichia coli</i>","publication_year":2014,"publication_date":"2014-10-13","ids":{"openalex":"https://openalex.org/W2130311175","doi":"https://doi.org/10.1093/bioinformatics/btu671","mag":"2130311175"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btu671","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btu671","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/31/3/306/49011124/bioinformatics_31_3_306.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/31/3/306/49011124/bioinformatics_31_3_306.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044558261","display_name":"James Vlasblom","orcid":null},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"James Vlasblom","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084666204","display_name":"Khalid Zuberi","orcid":null},"institutions":[{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Khalid Zuberi","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023279093","display_name":"Harold Rodriguez","orcid":null},"institutions":[{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Harold Rodriguez","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016382034","display_name":"Roland Arnold","orcid":"https://orcid.org/0000-0002-7496-7578"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Roland Arnold","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088928588","display_name":"Alla Gagarinova","orcid":"https://orcid.org/0000-0002-6521-6406"},"institutions":[{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Alla Gagarinova","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082646851","display_name":"Viktor Deineko","orcid":null},"institutions":[{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Viktor Deineko","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040735180","display_name":"Ashwani Kumar","orcid":"https://orcid.org/0000-0002-2100-900X"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ashwani Kumar","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103638773","display_name":"Elisa Leung","orcid":null},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Elisa Leung","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011288111","display_name":"Kamran Rizzolo","orcid":"https://orcid.org/0000-0003-2869-9768"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Kamran Rizzolo","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014369626","display_name":"Bahram Samanfar","orcid":"https://orcid.org/0000-0001-6625-2153"},"institutions":[{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Bahram Samanfar","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119246412","display_name":"Luke J. Chang","orcid":"https://orcid.org/0000-0002-6621-8120"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Luke Chang","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063358488","display_name":"Sadhna Phanse","orcid":"https://orcid.org/0000-0001-6306-0551"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Sadhna Phanse","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005719112","display_name":"Ashkan Golshani","orcid":"https://orcid.org/0009-0008-9171-6245"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ashkan Golshani","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102837838","display_name":"Jack Greenblatt","orcid":"https://orcid.org/0000-0003-1762-2861"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jack F. Greenblatt","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077991160","display_name":"Walid A. Houry","orcid":"https://orcid.org/0000-0002-1861-3441"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Walid A. Houry","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076978787","display_name":"Andrew Emili","orcid":"https://orcid.org/0000-0001-8995-246X"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Andrew Emili","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035010657","display_name":"Quaid Morris","orcid":"https://orcid.org/0000-0002-2760-6999"},"institutions":[{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Quaid Morris","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010789029","display_name":"Gary D. Bader","orcid":"https://orcid.org/0000-0003-0185-8861"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Gary Bader","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073300511","display_name":"Mohan Babu","orcid":"https://orcid.org/0000-0003-4118-6406"},"institutions":[{"id":"https://openalex.org/I194028371","display_name":"University of Regina","ror":"https://ror.org/03dzc0485","country_code":"CA","type":"education","lineage":["https://openalex.org/I194028371"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Mohan Babu","raw_affiliation_strings":["1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada"],"affiliations":[{"raw_affiliation_string":"1 Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 2 Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada, 3 Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 4 Department of Computer Science, University of Regina, Regina, Saskatchewan S4S0A2, Canada, 5 Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada, 6 Department of Biology, Carleton University, Ottawa, Ontario K1S 5B6, Canada and 7 Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada","institution_ids":["https://openalex.org/I194028371","https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":19,"corresponding_author_ids":["https://openalex.org/A5044558261"],"corresponding_institution_ids":["https://openalex.org/I185261750","https://openalex.org/I194028371"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":3.2735,"has_fulltext":true,"cited_by_count":45,"citation_normalized_percentile":{"value":0.92814863,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"31","issue":"3","first_page":"306","last_page":"310"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9968000054359436,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.6817849278450012},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.562722384929657},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.48095813393592834},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.480143278837204},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.4788082242012024},{"id":"https://openalex.org/keywords/biogenesis","display_name":"Biogenesis","score":0.4444449245929718},{"id":"https://openalex.org/keywords/resource","display_name":"Resource (disambiguation)","score":0.4419267773628235},{"id":"https://openalex.org/keywords/protein-function","display_name":"Protein function","score":0.4150102138519287},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.40791556239128113},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.22858554124832153}],"concepts":[{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.6817849278450012},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.562722384929657},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48095813393592834},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.480143278837204},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.4788082242012024},{"id":"https://openalex.org/C131934819","wikidata":"https://www.wikidata.org/wiki/Q135390","display_name":"Biogenesis","level":3,"score":0.4444449245929718},{"id":"https://openalex.org/C206345919","wikidata":"https://www.wikidata.org/wiki/Q20380951","display_name":"Resource (disambiguation)","level":2,"score":0.4419267773628235},{"id":"https://openalex.org/C2986374874","wikidata":"https://www.wikidata.org/wiki/Q8054","display_name":"Protein function","level":3,"score":0.4150102138519287},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.40791556239128113},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22858554124832153},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btu671","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btu671","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/31/3/306/49011124/bioinformatics_31_3_306.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4308668","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4308668","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/bf622912-0724-42f9-9822-9ef56c178f59","is_oa":false,"landing_page_url":"https://research.birmingham.ac.uk/en/publications/bf622912-0724-42f9-9822-9ef56c178f59","pdf_url":null,"source":{"id":"https://openalex.org/S4306402634","display_name":"University of Birmingham Research Portal (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Vlasblom, J, Zuberi, K, Rodriguez, H, Arnold, R, Gagarinova, A, Deineko, V, Kumar, A, Leung, E, Rizzolo, K, Samanfar, B, Chang, L, Phanse, S, Golshani, A, Greenblatt, J F, Houry, W A, Emili, A, Morris, Q, Bader, G & Babu, M 2014, 'Novel function discovery with GeneMANIA: a new integrated resource for gene function prediction in Escherichia coli', Bioinformatics, vol. 31, no. 3, pp. 306-310. https://doi.org/10.1093/bioinformatics/btu671","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btu671","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btu671","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/31/3/306/49011124/bioinformatics_31_3_306.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1114180654","display_name":null,"funder_award_id":"Vanier","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G3550942210","display_name":null,"funder_award_id":"MOP-13","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G4389354971","display_name":null,"funder_award_id":"Research","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G4831182661","display_name":null,"funder_award_id":"MOP-130374","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G538508981","display_name":null,"funder_award_id":"Fellowship","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G5782839332","display_name":null,"funder_award_id":"New Investigator","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G6282788884","display_name":null,"funder_award_id":"Canadian Institutes of Health","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G6344930758","display_name":null,"funder_award_id":"Scholarship","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G727862659","display_name":null,"funder_award_id":"Canadian Institutes of Health Research (CIHR)","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"}],"funders":[{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2130311175.pdf","grobid_xml":"https://content.openalex.org/works/W2130311175.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W147290053","https://openalex.org/W1564219524","https://openalex.org/W1974393054","https://openalex.org/W1975281749","https://openalex.org/W2018326742","https://openalex.org/W2018756605","https://openalex.org/W2026875682","https://openalex.org/W2048593866","https://openalex.org/W2061004320","https://openalex.org/W2066503489","https://openalex.org/W2068457504","https://openalex.org/W2084196805","https://openalex.org/W2097508475","https://openalex.org/W2105924489","https://openalex.org/W2108102049","https://openalex.org/W2111967267","https://openalex.org/W2113273527","https://openalex.org/W2116443392","https://openalex.org/W2117087393","https://openalex.org/W2124649441","https://openalex.org/W2137012036","https://openalex.org/W2140337827","https://openalex.org/W2141915211","https://openalex.org/W2150671144","https://openalex.org/W2155972151","https://openalex.org/W2159675211","https://openalex.org/W2166542841","https://openalex.org/W2770983033"],"related_works":["https://openalex.org/W2360987025","https://openalex.org/W2387178301","https://openalex.org/W3144733943","https://openalex.org/W2785993273","https://openalex.org/W2382269147","https://openalex.org/W3184323118","https://openalex.org/W2799462113","https://openalex.org/W36834100","https://openalex.org/W2376819606","https://openalex.org/W2068989602"],"abstract_inverted_index":{"Abstract":[0],"Motivation:":[1],"The":[2,121],"model":[3,51,96],"bacterium":[4],"Escherichia":[5],"coli":[6],"is":[7,26],"among":[8],"the":[9,43,68],"best":[10],"studied":[11],"prokaryotes,":[12],"yet":[13],"nearly":[14],"half":[15],"of":[16,21,30,74],"its":[17],"proteins":[18],"are":[19,147],"still":[20],"unknown":[22],"biological":[23],"function.":[24],"This":[25],"despite":[27],"a":[28],"wealth":[29],"available":[31,148],"large-scale":[32],"physical":[33],"and":[34,66,78,98,118],"genetic":[35],"interaction":[36,64],"data.":[37],"To":[38],"address":[39],"this,":[40],"we":[41],"extended":[42],"GeneMANIA":[44,69,122],"function":[45,126],"prediction":[46,127],"web":[47],"application":[48],"developed":[49],"for":[50,81,94,102,112,124,133],"eukaryotes":[52],"to":[53,71,91],"support":[54],"E.coli":[55,62],".":[56],"Results:":[57],"We":[58],"integrated":[59],"48":[60],"distinct":[61],"functional":[63,76,83],"datasets":[65],"used":[67],"algorithm":[70],"produce":[72],"thousands":[73],"novel":[75],"predictions":[77],"prioritize":[79],"genes":[80,105],"further":[82],"assays.":[84],"Our":[85],"analysis":[86],"achieved":[87],"cross-validation":[88],"performance":[89],"comparable":[90],"that":[92],"reported":[93],"eukaryotic":[95],"organisms,":[97],"revealed":[99],"new":[100,131],"functions":[101],"previously":[103],"uncharacterized":[104],"in":[106],"specific":[107],"bioprocesses,":[108],"including":[109],"components":[110],"required":[111],"cell":[113],"adhesion,":[114],"iron\u2013sulphur":[115],"complex":[116],"assembly":[117],"ribosome":[119],"biogenesis.":[120],"approach":[123],"network-based":[125],"provides":[128],"an":[129],"innovative":[130],"tool":[132],"probing":[134],"mechanisms":[135],"underlying":[136],"bacterial":[137],"bioprocesses.":[138],"Contact:":[139],"gary.bader@utoronto.ca":[140],";":[141],"mohan.babu@uregina.ca":[142],"Supplementary":[143,145],"information:":[144],"data":[146],"at":[149],"Bioinformatics":[150],"online.":[151]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":3}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2016-06-24T00:00:00"}