{"id":"https://openalex.org/W2142011660","doi":"https://doi.org/10.1093/bioinformatics/btt728","title":"Wigwams: identifying gene modules co-regulated across multiple biological conditions","display_name":"Wigwams: identifying gene modules co-regulated across multiple biological conditions","publication_year":2013,"publication_date":"2013-12-18","ids":{"openalex":"https://openalex.org/W2142011660","doi":"https://doi.org/10.1093/bioinformatics/btt728","mag":"2142011660","pmid":"https://pubmed.ncbi.nlm.nih.gov/24351708"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btt728","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btt728","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/30/7/962/17148590/btt728.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/30/7/962/17148590/btt728.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090126209","display_name":"Krzysztof Pola\u0144ski","orcid":"https://orcid.org/0000-0002-2586-9576"},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Krzysztof Polanski","raw_affiliation_strings":["1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK","institution_ids":["https://openalex.org/I39555362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036142864","display_name":"Johanna Rhodes","orcid":"https://orcid.org/0000-0002-1338-7860"},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Johanna Rhodes","raw_affiliation_strings":["1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK","institution_ids":["https://openalex.org/I39555362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075369722","display_name":"Claire Hill","orcid":"https://orcid.org/0000-0002-2481-5162"},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Claire Hill","raw_affiliation_strings":["1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK","institution_ids":["https://openalex.org/I39555362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115603665","display_name":"Peijun Zhang","orcid":"https://orcid.org/0000-0002-7047-7133"},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Peijun Zhang","raw_affiliation_strings":["1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK","institution_ids":["https://openalex.org/I39555362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103563452","display_name":"Dafyd J. Jenkins","orcid":null},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Dafyd J. Jenkins","raw_affiliation_strings":["1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK","institution_ids":["https://openalex.org/I39555362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107385959","display_name":"Steven J. Kiddle","orcid":"https://orcid.org/0000-0003-4350-7437"},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Steven J. Kiddle","raw_affiliation_strings":["1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK","institution_ids":["https://openalex.org/I39555362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048297020","display_name":"Aleksey Jironkin","orcid":"https://orcid.org/0000-0002-5450-0479"},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Aleksey Jironkin","raw_affiliation_strings":["1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK","institution_ids":["https://openalex.org/I39555362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062748038","display_name":"Jim Beynon","orcid":null},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jim Beynon","raw_affiliation_strings":["1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK","institution_ids":["https://openalex.org/I39555362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031128819","display_name":"Vicky Buchanan\u2010Wollaston","orcid":null},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Vicky Buchanan-Wollaston","raw_affiliation_strings":["1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK","institution_ids":["https://openalex.org/I39555362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026718378","display_name":"Sascha Ott","orcid":"https://orcid.org/0000-0002-5411-8114"},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sascha Ott","raw_affiliation_strings":["1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK","institution_ids":["https://openalex.org/I39555362"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051420519","display_name":"Katherine Denby","orcid":"https://orcid.org/0000-0002-7857-6814"},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Katherine J. Denby","raw_affiliation_strings":["1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Warwick Systems Biology Centre and 2School of Life Sciences, University of Warwick, CV4 7AL, UK","institution_ids":["https://openalex.org/I39555362"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":11,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":5.5319,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.95273114,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"30","issue":"7","first_page":"962","last_page":"970"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.39649999141693115,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.39649999141693115,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.12359999865293503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11237","display_name":"Plant Gene Expression Analysis","score":0.10520000010728836,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5663080811500549},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5065873861312866},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.49448680877685547},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3580033779144287},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.32150620222091675}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5663080811500549},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5065873861312866},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.49448680877685547},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3580033779144287},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.32150620222091675}],"mesh":[{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018506","descriptor_name":"Gene Expression Regulation, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018506","descriptor_name":"Gene Expression Regulation, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018506","descriptor_name":"Gene Expression Regulation, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018506","descriptor_name":"Gene Expression Regulation, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1093/bioinformatics/btt728","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btt728","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/30/7/962/17148590/btt728.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:24351708","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24351708","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:kclpure.kcl.ac.uk:openaire/cca43239-2941-4a0b-a6e5-c7ff77d57ca2","is_oa":true,"landing_page_url":"https://kclpure.kcl.ac.uk/portal/en/publications/cca43239-2941-4a0b-a6e5-c7ff77d57ca2","pdf_url":null,"source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Polanski, K, Rhodes, J, Hill, C, Zhang, P, Jenkins, D J, Kiddle, S, Jironkin, A, Beynon, J, Buchanan-Wollaston, V, Ott, S & Denby, K J 2014, 'Wigwams : identifying gene modules co-regulated across multiple biological conditions', Bioinformatics (Oxford, England), vol. N/A, no. N/A, N/A, pp. N/A. https://doi.org/10.1093/bioinformatics/btt728","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:wrap.warwick.ac.uk:60264","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306400665","display_name":"Warwick Research Archive Portal (University of Warwick)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I39555362","host_organization_name":"University of Warwick","host_organization_lineage":["https://openalex.org/I39555362"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2969376","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3967106","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/386b204e-939f-41c5-a5d3-4f8a03ac4817","is_oa":false,"landing_page_url":"https://research.birmingham.ac.uk/en/publications/386b204e-939f-41c5-a5d3-4f8a03ac4817","pdf_url":null,"source":{"id":"https://openalex.org/S4306402634","display_name":"University of Birmingham Research Portal (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Polanski, K, Rhodes, J, Hill, C, Zhang, P, Jenkins, D J, Kiddle, S J, Jironkin, A, Beynon, J, Buchanan-Wollaston, V, Ott, S & Denby, K J 2014, 'Wigwams : identifying gene modules co-regulated across multiple biological conditions', Bioinformatics, vol. 30, no. 7, pp. 962-70. https://doi.org/10.1093/bioinformatics/btt728","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btt728","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btt728","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/30/7/962/17148590/btt728.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10","score":0.6000000238418579}],"awards":[{"id":"https://openalex.org/G5567334210","display_name":null,"funder_award_id":"MR/L011859/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G682149586","display_name":null,"funder_award_id":"BB/F005806/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2142011660.pdf"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W1869362176","https://openalex.org/W1962904612","https://openalex.org/W1982335518","https://openalex.org/W1987940107","https://openalex.org/W2004975621","https://openalex.org/W2014956626","https://openalex.org/W2045716015","https://openalex.org/W2059699217","https://openalex.org/W2059754118","https://openalex.org/W2084799820","https://openalex.org/W2092870907","https://openalex.org/W2095588912","https://openalex.org/W2097903517","https://openalex.org/W2100707780","https://openalex.org/W2100945610","https://openalex.org/W2103017472","https://openalex.org/W2103696082","https://openalex.org/W2105498076","https://openalex.org/W2107536885","https://openalex.org/W2107593640","https://openalex.org/W2110065044","https://openalex.org/W2111051136","https://openalex.org/W2112044923","https://openalex.org/W2117926385","https://openalex.org/W2122056398","https://openalex.org/W2126623160","https://openalex.org/W2128495808","https://openalex.org/W2132792723","https://openalex.org/W2135030836","https://openalex.org/W2135222648","https://openalex.org/W2137596615","https://openalex.org/W2143748913","https://openalex.org/W2150466754","https://openalex.org/W2153976088","https://openalex.org/W2157485672","https://openalex.org/W2161732139","https://openalex.org/W2162151071","https://openalex.org/W2164518967","https://openalex.org/W2171030481","https://openalex.org/W2561675875","https://openalex.org/W4231842606","https://openalex.org/W6641275872","https://openalex.org/W6665522443","https://openalex.org/W6674379859"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2082860237","https://openalex.org/W2119695867","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W2046158694","https://openalex.org/W2788277189","https://openalex.org/W1971568933","https://openalex.org/W2034625591"],"abstract_inverted_index":{"MOTIVATION:":[0],"Identification":[1],"of":[2,4,34,44,68,79,107,114,130,138,144,153,208,230,237,245],"modules":[3,67,98,205,233],"co-regulated":[5,69],"genes":[6,21,48,70],"is":[7,89,146,191,254],"a":[8,77,90,150,154,228],"crucial":[9],"first":[10],"step":[11],"towards":[12],"dissecting":[13],"the":[14,80,126],"regulatory":[15,156,215],"circuitry":[16],"underlying":[17],"biological":[18],"processes.":[19],"Co-regulated":[20],"are":[22,49,173],"likely":[23],"to":[24,55,95,181,199],"reveal":[25],"themselves":[26],"by":[27],"showing":[28,99],"tight":[29,74],"co-expression,":[30],"e.g.":[31],"high":[32],"correlation":[33],"expression":[35,109,116,136,179,225],"profiles":[36],"across":[37,76,132],"multiple":[38,104,159],"time":[39,81,105,120,166,176,223],"series":[40,106,121,224],"datasets.":[41],"However,":[42],"numbers":[43],"up-":[45],"or":[46,128],"downregulated":[47],"often":[50],"large,":[51],"making":[52],"it":[53],"difficult":[54],"discriminate":[56],"between":[57],"dependent":[58],"co-expression":[59,75],"resulting":[60],"from":[61],"co-regulation":[62,102],"and":[63,92,123,168,193,206,252],"independent":[64],"co-expression.":[65],"Furthermore,":[66],"may":[71],"only":[72],"show":[73,84,211],"subset":[78,143],"series,":[82],"i.e.":[83],"condition-dependent":[85,155],"regulation.":[86],"RESULTS:":[87],"Wigwams":[88,111,161,217],"simple":[91],"efficient":[93],"method":[94],"identify":[96],"gene":[97,108,115,140,196,204],"evidence":[100,212],"for":[101,213],"in":[103,141],"data.":[110],"analyzes":[112],"similarities":[113],"patterns":[117],"within":[118],"each":[119,139,142],"(condition)":[122],"directly":[124],"tests":[125],"dependence":[127],"independence":[129],"these":[131],"different":[133,175,235],"conditions.":[134,238],"The":[135,189],"pattern":[137],"conditions":[145,183,209],"tested":[147],"statistically":[148],"as":[149],"potential":[151],"signature":[152],"mechanism":[157],"regulating":[158],"genes.":[160],"does":[162],"not":[163],"require":[164],"particular":[165],"points":[167],"can":[169,184],"process":[170],"datasets":[171],"that":[172,210],"on":[174,202],"scales.":[177],"Differential":[178],"relative":[180],"control":[182],"be":[185,200],"taken":[186],"into":[187],"account.":[188],"output":[190],"succinct":[192],"non-redundant,":[194],"enabling":[195],"network":[197],"reconstruction":[198],"focused":[201],"those":[203],"combinations":[207,236],"shared":[214],"mechanisms.":[216],"was":[218],"run":[219],"using":[220],"six":[221],"Arabidopsis":[222],"datasets,":[226],"producing":[227],"set":[229],"biologically":[231],"significant":[232],"spanning":[234],"AVAILABILITY":[239],"AND":[240],"IMPLEMENTATION:":[241],"A":[242],"Matlab":[243],"implementation":[244],"Wigwams,":[246],"complete":[247],"with":[248],"graphical":[249],"user":[250],"interfaces":[251],"documentation,":[253],"available":[255],"at:":[256],"warwick.ac.uk/wigwams.":[257],".":[258]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}
