{"id":"https://openalex.org/W2100985529","doi":"https://doi.org/10.1093/bioinformatics/btt693","title":"AISAIC: a software suite for accurate identification of significant aberrations in cancers","display_name":"AISAIC: a software suite for accurate identification of significant aberrations in cancers","publication_year":2013,"publication_date":"2013-11-29","ids":{"openalex":"https://openalex.org/W2100985529","doi":"https://doi.org/10.1093/bioinformatics/btt693","mag":"2100985529","pmid":"https://pubmed.ncbi.nlm.nih.gov/24292941"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btt693","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btt693","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/30/3/431/48914525/bioinformatics_30_3_431.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/30/3/431/48914525/bioinformatics_30_3_431.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102203376","display_name":"Bai Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Bai Zhang","raw_affiliation_strings":["1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA"],"affiliations":[{"raw_affiliation_string":"1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I184565670","https://openalex.org/I859038795","https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042165656","display_name":"Xuchu Hou","orcid":null},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xuchu Hou","raw_affiliation_strings":["1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA"],"affiliations":[{"raw_affiliation_string":"1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I184565670","https://openalex.org/I859038795","https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017698164","display_name":"Xiguo Yuan","orcid":"https://orcid.org/0000-0002-0822-5189"},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiguo Yuan","raw_affiliation_strings":["1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA"],"affiliations":[{"raw_affiliation_string":"1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I184565670","https://openalex.org/I859038795","https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058026421","display_name":"Ie\u2212Ming Shih","orcid":"https://orcid.org/0000-0002-1084-2071"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ie-Ming Shih","raw_affiliation_strings":["1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA"],"affiliations":[{"raw_affiliation_string":"1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I184565670","https://openalex.org/I859038795","https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072282421","display_name":"Zhen Zhang","orcid":"https://orcid.org/0000-0002-6512-1458"},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhen Zhang","raw_affiliation_strings":["1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA"],"affiliations":[{"raw_affiliation_string":"1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I184565670","https://openalex.org/I859038795","https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011322600","display_name":"Robert Clarke","orcid":"https://orcid.org/0000-0002-9278-0854"},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Clarke","raw_affiliation_strings":["1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA","GEORGETOWN UNIVERSITY"],"affiliations":[{"raw_affiliation_string":"1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I184565670","https://openalex.org/I859038795","https://openalex.org/I145311948"]},{"raw_affiliation_string":"GEORGETOWN UNIVERSITY","institution_ids":["https://openalex.org/I184565670"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002841772","display_name":"Roger R. Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roger R. Wang","raw_affiliation_strings":["1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA"],"affiliations":[{"raw_affiliation_string":"1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I184565670","https://openalex.org/I859038795","https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100714948","display_name":"Yi Fu","orcid":"https://orcid.org/0000-0001-6911-0724"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yi Fu","raw_affiliation_strings":["1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA"],"affiliations":[{"raw_affiliation_string":"1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I184565670","https://openalex.org/I859038795","https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037218810","display_name":"Subha Madhavan","orcid":"https://orcid.org/0000-0001-7617-3547"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Subha Madhavan","raw_affiliation_strings":["1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA","GEORGETOWN UNIVERSITY"],"affiliations":[{"raw_affiliation_string":"1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I184565670","https://openalex.org/I859038795","https://openalex.org/I145311948"]},{"raw_affiliation_string":"GEORGETOWN UNIVERSITY","institution_ids":["https://openalex.org/I184565670"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010574453","display_name":"Yue Wang","orcid":"https://orcid.org/0000-0002-3480-3544"},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yue Wang","raw_affiliation_strings":["1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA"],"affiliations":[{"raw_affiliation_string":"1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I184565670","https://openalex.org/I859038795","https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076006520","display_name":"Guoqiang Yu","orcid":"https://orcid.org/0000-0002-6743-7413"},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guoqiang Yu","raw_affiliation_strings":["1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA","Johns Hopkins University"],"affiliations":[{"raw_affiliation_string":"1 Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 3School of Computer Science and Technology, Xidian University, Xi\u2019an 710126, China, 4Department of Oncology and 5Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, 6Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA 7Department of Oncology and 8Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and 9Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA","institution_ids":["https://openalex.org/I184565670","https://openalex.org/I859038795","https://openalex.org/I145311948"]},{"raw_affiliation_string":"Johns Hopkins University","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5102203376"],"corresponding_institution_ids":["https://openalex.org/I145311948","https://openalex.org/I184565670","https://openalex.org/I859038795"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.4666,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.68801279,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"30","issue":"3","first_page":"431","last_page":"433"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7607753276824951},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.5921747088432312},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.5827549695968628},{"id":"https://openalex.org/keywords/scripting-language","display_name":"Scripting language","score":0.5449723601341248},{"id":"https://openalex.org/keywords/java","display_name":"Java","score":0.5357133150100708},{"id":"https://openalex.org/keywords/executable","display_name":"Executable","score":0.5218190550804138},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.48557206988334656},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.48024871945381165},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.45331716537475586},{"id":"https://openalex.org/keywords/application-programming-interface","display_name":"Application programming interface","score":0.41623321175575256},{"id":"https://openalex.org/keywords/plug-in","display_name":"Plug-in","score":0.41497087478637695},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.2811139225959778},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.13054096698760986}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7607753276824951},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.5921747088432312},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.5827549695968628},{"id":"https://openalex.org/C61423126","wikidata":"https://www.wikidata.org/wiki/Q187432","display_name":"Scripting language","level":2,"score":0.5449723601341248},{"id":"https://openalex.org/C548217200","wikidata":"https://www.wikidata.org/wiki/Q251","display_name":"Java","level":2,"score":0.5357133150100708},{"id":"https://openalex.org/C160145156","wikidata":"https://www.wikidata.org/wiki/Q778586","display_name":"Executable","level":2,"score":0.5218190550804138},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.48557206988334656},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.48024871945381165},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.45331716537475586},{"id":"https://openalex.org/C99613125","wikidata":"https://www.wikidata.org/wiki/Q165194","display_name":"Application programming interface","level":2,"score":0.41623321175575256},{"id":"https://openalex.org/C4924752","wikidata":"https://www.wikidata.org/wiki/Q184148","display_name":"Plug-in","level":2,"score":0.41497087478637695},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.2811139225959778},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13054096698760986},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056915","descriptor_name":"DNA Copy Number Variations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056915","descriptor_name":"DNA Copy Number Variations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056915","descriptor_name":"DNA Copy Number Variations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btt693","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btt693","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/30/3/431/48914525/bioinformatics_30_3_431.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:24292941","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24292941","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:europepmc.org:3280234","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3904524","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btt693","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btt693","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/30/3/431/48914525/bioinformatics_30_3_431.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1369073207","display_name":null,"funder_award_id":"CA149147","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G1453689866","display_name":null,"funder_award_id":"CA164384","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G2087396116","display_name":null,"funder_award_id":"China","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3102874822","display_name":null,"funder_award_id":"CA160036","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G3198118584","display_name":null,"funder_award_id":"CA160036","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3317480652","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3811313036","display_name":null,"funder_award_id":"164384","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4147625295","display_name":null,"funder_award_id":"CA164384","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5573669005","display_name":null,"funder_award_id":"149147","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5900261227","display_name":null,"funder_award_id":"61201312","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5994120800","display_name":null,"funder_award_id":"Natural","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6967836897","display_name":null,"funder_award_id":"CA149147","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8198795195","display_name":null,"funder_award_id":"00001","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8244010491","display_name":null,"funder_award_id":"61070137","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2100985529.pdf","grobid_xml":"https://content.openalex.org/works/W2100985529.grobid-xml"},"referenced_works_count":5,"referenced_works":["https://openalex.org/W2011649969","https://openalex.org/W2153056550","https://openalex.org/W2153631649","https://openalex.org/W2161266543","https://openalex.org/W2170490448"],"related_works":["https://openalex.org/W4287378204","https://openalex.org/W2981957539","https://openalex.org/W2093416473","https://openalex.org/W3036080447","https://openalex.org/W4238519267","https://openalex.org/W2598672065","https://openalex.org/W1993817217","https://openalex.org/W3120610872","https://openalex.org/W1638297612","https://openalex.org/W2523911541"],"abstract_inverted_index":{"AISAIC":[0],"is":[1],"available":[2],"as":[3],"a":[4,8],"Java":[5],"application,":[6],"with":[7],"user's":[9],"guide":[10],"and":[11],"source":[12],"code,":[13],"at":[14],"https://code.google.com/p/aisaic/.":[15]},"counts_by_year":[{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-04-18T07:56:08.524223","created_date":"2025-10-10T00:00:00"}