{"id":"https://openalex.org/W2171981969","doi":"https://doi.org/10.1093/bioinformatics/btt417","title":"BLAD: A comprehensive database of widely circulated beta-lactamases","display_name":"BLAD: A comprehensive database of widely circulated beta-lactamases","publication_year":2013,"publication_date":"2013-08-13","ids":{"openalex":"https://openalex.org/W2171981969","doi":"https://doi.org/10.1093/bioinformatics/btt417","mag":"2171981969","pmid":"https://pubmed.ncbi.nlm.nih.gov/23943635"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btt417","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btt417","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001487177","display_name":"Mohd Danishuddin","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohd Danishuddin","raw_affiliation_strings":["Interdisciplinary Biotechnology Unit, A. M. U., Aligarh 202002, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Interdisciplinary Biotechnology Unit, A. M. U., Aligarh 202002, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mohd Hassan Baig","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohd Hassan Baig","raw_affiliation_strings":["Interdisciplinary Biotechnology Unit, A. M. U., Aligarh 202002, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Interdisciplinary Biotechnology Unit, A. M. U., Aligarh 202002, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032729864","display_name":"Lalima Kaushal","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lalima Kaushal","raw_affiliation_strings":["Interdisciplinary Biotechnology Unit, A. M. U., Aligarh 202002, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Interdisciplinary Biotechnology Unit, A. M. U., Aligarh 202002, India","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100412507","display_name":"Asad U. Khan","orcid":"https://orcid.org/0000-0001-9191-9423"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Asad U Khan","raw_affiliation_strings":["Interdisciplinary Biotechnology Unit, A. M. U., Aligarh 202002, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Interdisciplinary Biotechnology Unit, A. M. U., Aligarh 202002, India","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.6715,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.64304503,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"29","issue":"19","first_page":"2515","last_page":"2516"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9715999960899353,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9715999960899353,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.532590389251709},{"id":"https://openalex.org/keywords/multiple-drug-resistance","display_name":"Multiple drug resistance","score":0.5162289142608643},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.48907262086868286},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.48864346742630005},{"id":"https://openalex.org/keywords/beta","display_name":"BETA (programming language)","score":0.47602230310440063},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"Drug resistance","score":0.44370871782302856},{"id":"https://openalex.org/keywords/antibiotic-resistance","display_name":"Antibiotic resistance","score":0.44179767370224},{"id":"https://openalex.org/keywords/horizontal-gene-transfer","display_name":"Horizontal gene transfer","score":0.42506492137908936},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.4152195453643799},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.41511648893356323},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3499678373336792},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.34541335701942444},{"id":"https://openalex.org/keywords/antibiotics","display_name":"Antibiotics","score":0.2896603047847748},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.08514276146888733},{"id":"https://openalex.org/keywords/phylogenetics","display_name":"Phylogenetics","score":0.08377206325531006}],"concepts":[{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.532590389251709},{"id":"https://openalex.org/C133936738","wikidata":"https://www.wikidata.org/wiki/Q643839","display_name":"Multiple drug resistance","level":3,"score":0.5162289142608643},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.48907262086868286},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.48864346742630005},{"id":"https://openalex.org/C2776174256","wikidata":"https://www.wikidata.org/wiki/Q830842","display_name":"BETA (programming language)","level":2,"score":0.47602230310440063},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.44370871782302856},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.44179767370224},{"id":"https://openalex.org/C92938381","wikidata":"https://www.wikidata.org/wiki/Q83185","display_name":"Horizontal gene transfer","level":4,"score":0.42506492137908936},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4152195453643799},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41511648893356323},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3499678373336792},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.34541335701942444},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.2896603047847748},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.08514276146888733},{"id":"https://openalex.org/C90132467","wikidata":"https://www.wikidata.org/wiki/Q171184","display_name":"Phylogenetics","level":3,"score":0.08377206325531006}],"mesh":[{"descriptor_ui":"D001618","descriptor_name":"beta-Lactamases","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D001618","descriptor_name":"beta-Lactamases","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D001618","descriptor_name":"beta-Lactamases","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D001618","descriptor_name":"beta-Lactamases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001618","descriptor_name":"beta-Lactamases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001618","descriptor_name":"beta-Lactamases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030561","descriptor_name":"Databases, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030561","descriptor_name":"Databases, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030561","descriptor_name":"Databases, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btt417","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btt417","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:23943635","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23943635","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8100000023841858,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W2008274231","https://openalex.org/W2042588716","https://openalex.org/W2050939511","https://openalex.org/W2068168349","https://openalex.org/W2096489042","https://openalex.org/W2096820855","https://openalex.org/W2106612397","https://openalex.org/W2111516721","https://openalex.org/W2138169725","https://openalex.org/W2143378971","https://openalex.org/W2151496242","https://openalex.org/W2736046380","https://openalex.org/W6741261140"],"related_works":["https://openalex.org/W2264917134","https://openalex.org/W4249861864","https://openalex.org/W2505308311","https://openalex.org/W2972620994","https://openalex.org/W3149326312","https://openalex.org/W1833347391","https://openalex.org/W4200170072","https://openalex.org/W2061885127","https://openalex.org/W2807780787","https://openalex.org/W3003357357"],"abstract_inverted_index":{"MOTIVATION:":[0],"Beta-lactamases":[1],"confer":[2],"resistance":[3,68,98,137],"to":[4,39,77,92,120],"a":[5,31],"broad":[6],"range":[7],"of":[8,17,36,135,142],"antibiotics":[9],"and":[10,19,42,50,59,67,97,117,138],"inhibitors":[11],"by":[12],"accumulating":[13],"mutations.":[14],"The":[15,25,147],"number":[16],"beta-lactamases":[18],"their":[20,51,60,65],"variants":[21,52,62],"is":[22],"steadily":[23],"increasing.":[24],"horizontal":[26],"gene":[27,103],"transfer":[28],"likely":[29],"plays":[30],"major":[32],"role":[33],"in":[34,105],"dissemination":[35],"these":[37,57],"markers":[38],"new":[40],"environments":[41],"hosts.":[43],"Moreover,":[44],"information":[45,70,95,127],"about":[46],"the":[47,78,85,133,140,153],"beta-lactamase":[48,86],"classes":[49,58],"was":[53],"scattered.":[54],"Categorizing":[55],"all":[56],"associated":[61],"along":[63],"with":[64,109],"epidemiology":[66,134],"pattern":[69],"on":[71,81,100],"one":[72],"platform":[73],"could":[74],"be":[75,150],"helpful":[76],"researcher":[79],"working":[80],"multidrug-resistant":[82],"bacteria.":[83],"Thus,":[84],"database":[87,148],"(BLAD)":[88],"has":[89],"been":[90],"developed":[91],"provide":[93,130],"comprehensive":[94],"(epidemiology":[96],"pattern)":[99],"beta-lactamases.":[101],"Beta-lactamase":[102],"sequences":[104],"BLAD":[106,125],"are":[107],"linked":[108],"structural":[110],"data,":[111],"phenotypic":[112],"data":[113],"(i.e.":[114],"antibiotic":[115],"resistance)":[116],"literature":[118],"references":[119],"experimental":[121],"studies.":[122],"In":[123],"summary,":[124],"integrates":[126],"that":[128],"may":[129],"insight":[131],"into":[132],"multidrug":[136],"enable":[139],"designing":[141],"novel":[143],"drug":[144],"candidates.":[145],"AVAILABILITY:":[146],"can":[149],"accessed":[151],"from":[152],"website":[154],"www.blad.co.in.":[155]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}