{"id":"https://openalex.org/W2152416668","doi":"https://doi.org/10.1093/bioinformatics/btt181","title":"INstruct: a database of high-quality 3D structurally resolved protein interactome networks","display_name":"INstruct: a database of high-quality 3D structurally resolved protein interactome networks","publication_year":2013,"publication_date":"2013-04-19","ids":{"openalex":"https://openalex.org/W2152416668","doi":"https://doi.org/10.1093/bioinformatics/btt181","mag":"2152416668","pmid":"https://pubmed.ncbi.nlm.nih.gov/23599502"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btt181","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btt181","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/29/12/1577/48886155/bioinformatics_29_12_1577.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/29/12/1577/48886155/bioinformatics_29_12_1577.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089187341","display_name":"Michael J. Meyer","orcid":"https://orcid.org/0000-0003-1587-5347"},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael J. Meyer","raw_affiliation_strings":["1 Department of Biological Statistics and Computational Biology and 2Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853 and 3Tri-Institutional Training Program in Computational Biology and Medicine, New York, NY 10065, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Biological Statistics and Computational Biology and 2Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853 and 3Tri-Institutional Training Program in Computational Biology and Medicine, New York, NY 10065, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073031182","display_name":"Jishnu Das","orcid":"https://orcid.org/0000-0002-5747-064X"},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jishnu Das","raw_affiliation_strings":["1 Department of Biological Statistics and Computational Biology and 2Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853 and 3Tri-Institutional Training Program in Computational Biology and Medicine, New York, NY 10065, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Biological Statistics and Computational Biology and 2Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853 and 3Tri-Institutional Training Program in Computational Biology and Medicine, New York, NY 10065, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100706832","display_name":"Xiujuan Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiujuan Wang","raw_affiliation_strings":["1 Department of Biological Statistics and Computational Biology and 2Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853 and 3Tri-Institutional Training Program in Computational Biology and Medicine, New York, NY 10065, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Biological Statistics and Computational Biology and 2Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853 and 3Tri-Institutional Training Program in Computational Biology and Medicine, New York, NY 10065, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067174340","display_name":"Haiyuan Yu","orcid":"https://orcid.org/0000-0001-7597-6049"},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haiyuan Yu","raw_affiliation_strings":["1 Department of Biological Statistics and Computational Biology and 2Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853 and 3Tri-Institutional Training Program in Computational Biology and Medicine, New York, NY 10065, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Biological Statistics and Computational Biology and 2Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853 and 3Tri-Institutional Training Program in Computational Biology and Medicine, New York, NY 10065, USA","institution_ids":["https://openalex.org/I205783295"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5089187341"],"corresponding_institution_ids":["https://openalex.org/I205783295"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":4.9334,"has_fulltext":true,"cited_by_count":151,"citation_normalized_percentile":{"value":0.96079154,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"29","issue":"12","first_page":"1577","last_page":"1579"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9930999875068665,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9929999709129333,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interactome","display_name":"Interactome","score":0.8851632475852966},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7611803412437439},{"id":"https://openalex.org/keywords/interface","display_name":"Interface (matter)","score":0.6365301012992859},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.5780876874923706},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.5506722331047058},{"id":"https://openalex.org/keywords/upload","display_name":"Upload","score":0.5078964829444885},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.3699408173561096},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.3629465103149414},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3484675884246826},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.3133602738380432},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.15363919734954834},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.14429572224617004},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.14111986756324768},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.08338218927383423}],"concepts":[{"id":"https://openalex.org/C9760119","wikidata":"https://www.wikidata.org/wiki/Q841382","display_name":"Interactome","level":3,"score":0.8851632475852966},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7611803412437439},{"id":"https://openalex.org/C113843644","wikidata":"https://www.wikidata.org/wiki/Q901882","display_name":"Interface (matter)","level":4,"score":0.6365301012992859},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.5780876874923706},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.5506722331047058},{"id":"https://openalex.org/C71901391","wikidata":"https://www.wikidata.org/wiki/Q7126699","display_name":"Upload","level":2,"score":0.5078964829444885},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.3699408173561096},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.3629465103149414},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3484675884246826},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.3133602738380432},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15363919734954834},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.14429572224617004},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14111986756324768},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08338218927383423},{"id":"https://openalex.org/C129307140","wikidata":"https://www.wikidata.org/wiki/Q6795880","display_name":"Maximum bubble pressure method","level":3,"score":0.0},{"id":"https://openalex.org/C173608175","wikidata":"https://www.wikidata.org/wiki/Q232661","display_name":"Parallel computing","level":1,"score":0.0},{"id":"https://openalex.org/C157915830","wikidata":"https://www.wikidata.org/wiki/Q2928001","display_name":"Bubble","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054730","descriptor_name":"Protein Interaction Domains and Motifs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054730","descriptor_name":"Protein Interaction Domains and Motifs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054730","descriptor_name":"Protein Interaction Domains and Motifs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btt181","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btt181","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/29/12/1577/48886155/bioinformatics_29_12_1577.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:23599502","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23599502","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:europepmc.org:3029507","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3673217","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btt181","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btt181","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/29/12/1577/48886155/bioinformatics_29_12_1577.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1770727752","display_name":null,"funder_award_id":"1T32GM083937","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2208620826","display_name":null,"funder_award_id":"R01 CA167824","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2753821249","display_name":null,"funder_award_id":"R01 GM097358","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3179052432","display_name":null,"funder_award_id":"GM097358","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4183299434","display_name":null,"funder_award_id":"1T32GM083937","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4545154520","display_name":null,"funder_award_id":"T32GM083937","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6816119643","display_name":null,"funder_award_id":"R01 GM097358","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2152416668.pdf","grobid_xml":"https://content.openalex.org/works/W2152416668.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W2009405916","https://openalex.org/W2037442572","https://openalex.org/W2062533676","https://openalex.org/W2091789479","https://openalex.org/W2095492902","https://openalex.org/W2095867585","https://openalex.org/W2098656855","https://openalex.org/W2101330776","https://openalex.org/W2110845720","https://openalex.org/W2116435022","https://openalex.org/W2122863289","https://openalex.org/W2127554948","https://openalex.org/W2130479394","https://openalex.org/W2130687290","https://openalex.org/W2140883620","https://openalex.org/W2141885858","https://openalex.org/W2158197251","https://openalex.org/W2160232999","https://openalex.org/W2162128823","https://openalex.org/W2163480486","https://openalex.org/W2165253681","https://openalex.org/W2612240612","https://openalex.org/W2770983033","https://openalex.org/W2915108429","https://openalex.org/W4234464312","https://openalex.org/W4320301318"],"related_works":["https://openalex.org/W4292634579","https://openalex.org/W2964314049","https://openalex.org/W2022326234","https://openalex.org/W4388694323","https://openalex.org/W3215098729","https://openalex.org/W1531941329","https://openalex.org/W4243081378","https://openalex.org/W1979330259","https://openalex.org/W2622356054","https://openalex.org/W2804670115"],"abstract_inverted_index":{"INstruct":[0],"is":[1],"freely":[2],"available":[3],"on":[4],"the":[5],"web":[6],"at":[7],"http://instruct.yulab.org":[8],"with":[9],"all":[10],"major":[11],"browsers":[12],"supported.":[13]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":19},{"year":2021,"cited_by_count":27},{"year":2020,"cited_by_count":24},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":9}],"updated_date":"2026-03-26T15:22:09.906841","created_date":"2025-10-10T00:00:00"}