{"id":"https://openalex.org/W2109614625","doi":"https://doi.org/10.1093/bioinformatics/btt041","title":"AbCD: arbitrary coverage design for sequencing-based genetic studies","display_name":"AbCD: arbitrary coverage design for sequencing-based genetic studies","publication_year":2013,"publication_date":"2013-01-28","ids":{"openalex":"https://openalex.org/W2109614625","doi":"https://doi.org/10.1093/bioinformatics/btt041","mag":"2109614625","pmid":"https://pubmed.ncbi.nlm.nih.gov/23357921"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btt041","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btt041","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/29/6/799/447842/btt041.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/29/6/799/447842/btt041.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021432602","display_name":"Jian Kang","orcid":"https://orcid.org/0000-0002-5643-2668"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Jian Kang","raw_affiliation_strings":["1 Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada, 2Department of Biostatistics, 3Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, 4Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109 and 5Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599-7264, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada, 2Department of Biostatistics, 3Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, 4Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109 and 5Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599-7264, USA","institution_ids":["https://openalex.org/I114027177","https://openalex.org/I27837315","https://openalex.org/I168635309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111766465","display_name":"Kuan-Chieh Huang","orcid":null},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Kuan-Chieh Huang","raw_affiliation_strings":["1 Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada, 2Department of Biostatistics, 3Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, 4Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109 and 5Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599-7264, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada, 2Department of Biostatistics, 3Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, 4Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109 and 5Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599-7264, USA","institution_ids":["https://openalex.org/I114027177","https://openalex.org/I27837315","https://openalex.org/I168635309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005491829","display_name":"Zheng Xu","orcid":"https://orcid.org/0000-0003-0311-7004"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Zheng Xu","raw_affiliation_strings":["1 Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada, 2Department of Biostatistics, 3Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, 4Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109 and 5Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599-7264, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada, 2Department of Biostatistics, 3Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, 4Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109 and 5Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599-7264, USA","institution_ids":["https://openalex.org/I114027177","https://openalex.org/I27837315","https://openalex.org/I168635309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100413238","display_name":"Yunfei Wang","orcid":"https://orcid.org/0000-0001-7693-0595"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Yunfei Wang","raw_affiliation_strings":["1 Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada, 2Department of Biostatistics, 3Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, 4Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109 and 5Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599-7264, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada, 2Department of Biostatistics, 3Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, 4Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109 and 5Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599-7264, USA","institution_ids":["https://openalex.org/I114027177","https://openalex.org/I27837315","https://openalex.org/I168635309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078559681","display_name":"Gon\u00e7alo R. Abecasis","orcid":"https://orcid.org/0000-0003-1509-1825"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Gon\u00e7alo R. Abecasis","raw_affiliation_strings":["1 Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada, 2Department of Biostatistics, 3Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, 4Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109 and 5Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599-7264, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada, 2Department of Biostatistics, 3Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, 4Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109 and 5Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599-7264, USA","institution_ids":["https://openalex.org/I114027177","https://openalex.org/I27837315","https://openalex.org/I168635309"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100369208","display_name":"Yun Li","orcid":"https://orcid.org/0000-0002-3932-6329"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["CA","US"],"is_corresponding":true,"raw_author_name":"Yun Li","raw_affiliation_strings":["1 Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada, 2Department of Biostatistics, 3Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, 4Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109 and 5Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599-7264, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada, 2Department of Biostatistics, 3Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, 4Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109 and 5Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599-7264, USA","institution_ids":["https://openalex.org/I114027177","https://openalex.org/I27837315","https://openalex.org/I168635309"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100369208"],"corresponding_institution_ids":["https://openalex.org/I114027177","https://openalex.org/I168635309","https://openalex.org/I27837315"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":1.7995,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.85973566,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"29","issue":"6","first_page":"799","last_page":"801"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6689473986625671},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4419839382171631},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2144668996334076}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6689473986625671},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4419839382171631},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2144668996334076}],"mesh":[{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015810","descriptor_name":"Linkage Disequilibrium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015810","descriptor_name":"Linkage Disequilibrium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015810","descriptor_name":"Linkage Disequilibrium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D060005","descriptor_name":"Genotyping Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060005","descriptor_name":"Genotyping Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060005","descriptor_name":"Genotyping Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btt041","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btt041","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/29/6/799/447842/btt041.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:23357921","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23357921","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:europepmc.org:2934688","is_oa":false,"landing_page_url":"http://europepmc.org/articles/PMC3597143","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3597143","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3597143","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btt041","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btt041","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/29/6/799/447842/btt041.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/17","display_name":"Partnerships for the goals","score":0.47999998927116394}],"awards":[{"id":"https://openalex.org/G1749267336","display_name":null,"funder_award_id":"R01-HG006703","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G2334082896","display_name":null,"funder_award_id":"R01 HL117626","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2374905200","display_name":null,"funder_award_id":"R01 HG007022","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G2686916889","display_name":null,"funder_award_id":"RC2 HG005581","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G2731058611","display_name":null,"funder_award_id":"HG005581","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G6650825495","display_name":null,"funder_award_id":"R01 HG006292","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G7646016686","display_name":null,"funder_award_id":"R01-HG006292","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G7688584224","display_name":null,"funder_award_id":"R01 HG006703","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G8751898938","display_name":null,"funder_award_id":"HG007022","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1970707782","https://openalex.org/W1976593262","https://openalex.org/W1979543168","https://openalex.org/W1982516282","https://openalex.org/W2005935256","https://openalex.org/W2036210716","https://openalex.org/W2058839892","https://openalex.org/W2061596350","https://openalex.org/W2095848015","https://openalex.org/W2097211764","https://openalex.org/W2103903744","https://openalex.org/W2107697078","https://openalex.org/W2118526609","https://openalex.org/W2139224067","https://openalex.org/W2161644980","https://openalex.org/W2166501262"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W2358668433","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W2382290278","https://openalex.org/W2350741829","https://openalex.org/W2530322880","https://openalex.org/W1596801655","https://openalex.org/W2359140296"],"abstract_inverted_index":{"Abstract":[0],"Summary:":[1],"Recent":[2],"advances":[3],"in":[4,19],"sequencing":[5,13,24,121,199],"technologies":[6],"have":[7],"revolutionized":[8],"genetic":[9],"studies.":[10,44],"Although":[11],"high-coverage":[12],"can":[14,168],"uncover":[15],"most":[16],"variants":[17],"present":[18,33,89],"the":[20,40,101,221],"sequenced":[21],"sample,":[22],"low-coverage":[23],"is":[25,46,106,130],"appealing":[26],"for":[27,62,74,111,174],"its":[28,213],"cost":[29],"effectiveness.":[30],"Here,":[31],"we":[32,87],"AbCD":[34,45],"(arbitrary":[35],"coverage":[36,66],"design)":[37],"to":[38,56,99,137,153],"aid":[39],"design":[41],"of":[42,177,191],"sequencing-based":[43],"a":[47,107,131],"user-friendly":[48],"interface":[49,216],"providing":[50],"pre-estimated":[51],"effective":[52,162,170],"sample":[53,69,163,171],"sizes,":[54],"specific":[55],"each":[57],"minor":[58,159],"allele":[59,160],"frequency":[60],"category,":[61],"designs":[63],"with":[64],"arbitrary":[65,112],"(0.5\u201330\u00d7)":[67],"and":[68,73,82,94,116,124,141,179,193,209,217,220,225,230],"size":[70,172],"(20\u201310":[71],"000),":[72],"four":[75],"major":[76],"ethnic":[77],"groups":[78],"(Europeans,":[79],"Africans,":[80],"Asians":[81],"African":[83],"Americans).":[84],"In":[85],"addition,":[86],"also":[88],"two":[90],"software":[91],"tools:":[92],"ShotGun":[93,105,136,165,224],"DesignPlanner,":[95,226],"which":[96],"were":[97],"used":[98],"generate":[100,138],"estimates":[102],"behind":[103],"AbCD.":[104],"flexible":[108],"short-read":[109],"simulator":[110],"user-specified":[113],"read":[114,126],"length":[115],"average":[117],"depth,":[118],"allowing":[119],"cycle-specific":[120],"error":[122],"rates":[123],"realistic":[125],"depth":[127],"distributions.":[128],"DesignPlanner":[129,167],"full":[132],"pipeline":[133],"that":[134],"uses":[135,146],"sequence":[139,192],"data":[140,181,195],"performs":[142],"initial":[143],"SNP":[144],"discovery,":[145],"our":[147],"previously":[148],"presented":[149],"linkage":[150],"disequilibrium-aware":[151],"method":[152],"call":[154],"genotypes,":[155],"and,":[156],"finally,":[157],"provides":[158],"frequency-specific":[161],"sizes.":[164],"plus":[166,186,200],"accommodate":[169],"estimate":[173],"any":[175],"combination":[176,190],"high-depth":[178],"low-depth":[180,185],"(for":[182],"example,":[183,197],"whole-genome":[184],"exonic":[187],"high-depth)":[188],"or":[189],"genotype":[194],"[for":[196],"whole-exome":[198],"genotyping":[201],"from":[202],"existing":[203],"Genomewide":[204],"Association":[205],"Study":[206],"(GWAS)].":[207],"Availability":[208],"implementation:":[210],"AbCD,":[211],"including":[212,227],"downloadable":[214],"terminal":[215],"web-based":[218],"interface,":[219],"associated":[222],"tools":[223],"documentation,":[228],"examples":[229],"executables,":[231],"are":[232],"available":[233],"at":[234],"http://www.unc.edu/\u223cyunmli/AbCD.html.":[235],"Contact:":[236],"yunli@med.unc.edu":[237]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2}],"updated_date":"2026-07-02T09:51:11.867554","created_date":"2025-10-10T00:00:00"}