{"id":"https://openalex.org/W2159531362","doi":"https://doi.org/10.1093/bioinformatics/bts658","title":"A system for exact and approximate genetic linkage analysis of SNP data in large pedigrees","display_name":"A system for exact and approximate genetic linkage analysis of SNP data in large pedigrees","publication_year":2012,"publication_date":"2012-11-18","ids":{"openalex":"https://openalex.org/W2159531362","doi":"https://doi.org/10.1093/bioinformatics/bts658","mag":"2159531362"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/bts658","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bts658","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/29/2/197/48890668/bioinformatics_29_2_197.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/29/2/197/48890668/bioinformatics_29_2_197.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022593894","display_name":"Mark Silberstein","orcid":"https://orcid.org/0000-0001-9659-068X"},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I4394709267","display_name":"Israel Institute","ror":"https://ror.org/00xfkzq83","country_code":null,"type":"nonprofit","lineage":["https://openalex.org/I4394709267"]},{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I4210113309","display_name":"Bnai Zion Medical Center","ror":"https://ror.org/01yvj7247","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113309"]}],"countries":["CA","IL"],"is_corresponding":false,"raw_author_name":"Mark Silberstein","raw_affiliation_strings":["1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210113309","https://openalex.org/I174306211","https://openalex.org/I4394709267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028616817","display_name":"Omer Weissbrod","orcid":"https://orcid.org/0000-0001-9860-0626"},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I4210113309","display_name":"Bnai Zion Medical Center","ror":"https://ror.org/01yvj7247","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113309"]},{"id":"https://openalex.org/I4394709267","display_name":"Israel Institute","ror":"https://ror.org/00xfkzq83","country_code":null,"type":"nonprofit","lineage":["https://openalex.org/I4394709267"]},{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]}],"countries":["CA","IL"],"is_corresponding":true,"raw_author_name":"Omer Weissbrod","raw_affiliation_strings":["1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210113309","https://openalex.org/I174306211","https://openalex.org/I4394709267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048212553","display_name":"Lars Otten","orcid":null},"institutions":[{"id":"https://openalex.org/I4394709267","display_name":"Israel Institute","ror":"https://ror.org/00xfkzq83","country_code":null,"type":"nonprofit","lineage":["https://openalex.org/I4394709267"]},{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I4210113309","display_name":"Bnai Zion Medical Center","ror":"https://ror.org/01yvj7247","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113309"]}],"countries":["CA","IL"],"is_corresponding":false,"raw_author_name":"Lars Otten","raw_affiliation_strings":["1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210113309","https://openalex.org/I174306211","https://openalex.org/I4394709267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081143993","display_name":"Anna Tzemach","orcid":null},"institutions":[{"id":"https://openalex.org/I4210113309","display_name":"Bnai Zion Medical Center","ror":"https://ror.org/01yvj7247","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113309"]},{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I4394709267","display_name":"Israel Institute","ror":"https://ror.org/00xfkzq83","country_code":null,"type":"nonprofit","lineage":["https://openalex.org/I4394709267"]}],"countries":["CA","IL"],"is_corresponding":false,"raw_author_name":"Anna Tzemach","raw_affiliation_strings":["1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210113309","https://openalex.org/I174306211","https://openalex.org/I4394709267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020863413","display_name":"Andrei Anisenia","orcid":null},"institutions":[{"id":"https://openalex.org/I4394709267","display_name":"Israel Institute","ror":"https://ror.org/00xfkzq83","country_code":null,"type":"nonprofit","lineage":["https://openalex.org/I4394709267"]},{"id":"https://openalex.org/I4210113309","display_name":"Bnai Zion Medical Center","ror":"https://ror.org/01yvj7247","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113309"]},{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]}],"countries":["CA","IL"],"is_corresponding":false,"raw_author_name":"Andrei Anisenia","raw_affiliation_strings":["1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210113309","https://openalex.org/I174306211","https://openalex.org/I4394709267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015722567","display_name":"Oren Shtark","orcid":null},"institutions":[{"id":"https://openalex.org/I4394709267","display_name":"Israel Institute","ror":"https://ror.org/00xfkzq83","country_code":null,"type":"nonprofit","lineage":["https://openalex.org/I4394709267"]},{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I4210113309","display_name":"Bnai Zion Medical Center","ror":"https://ror.org/01yvj7247","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113309"]}],"countries":["CA","IL"],"is_corresponding":false,"raw_author_name":"Oren Shtark","raw_affiliation_strings":["1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210113309","https://openalex.org/I174306211","https://openalex.org/I4394709267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083843435","display_name":"Dvir Tuberg","orcid":null},"institutions":[{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I4394709267","display_name":"Israel Institute","ror":"https://ror.org/00xfkzq83","country_code":null,"type":"nonprofit","lineage":["https://openalex.org/I4394709267"]},{"id":"https://openalex.org/I4210113309","display_name":"Bnai Zion Medical Center","ror":"https://ror.org/01yvj7247","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113309"]},{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]}],"countries":["CA","IL"],"is_corresponding":false,"raw_author_name":"Dvir Tuberg","raw_affiliation_strings":["1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210113309","https://openalex.org/I174306211","https://openalex.org/I4394709267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021942351","display_name":"Eddie Galfrin","orcid":null},"institutions":[{"id":"https://openalex.org/I4210113309","display_name":"Bnai Zion Medical Center","ror":"https://ror.org/01yvj7247","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113309"]},{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I4394709267","display_name":"Israel Institute","ror":"https://ror.org/00xfkzq83","country_code":null,"type":"nonprofit","lineage":["https://openalex.org/I4394709267"]}],"countries":["CA","IL"],"is_corresponding":false,"raw_author_name":"Eddie Galfrin","raw_affiliation_strings":["1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210113309","https://openalex.org/I174306211","https://openalex.org/I4394709267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044588219","display_name":"Irena Gannon","orcid":null},"institutions":[{"id":"https://openalex.org/I4394709267","display_name":"Israel Institute","ror":"https://ror.org/00xfkzq83","country_code":null,"type":"nonprofit","lineage":["https://openalex.org/I4394709267"]},{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I4210113309","display_name":"Bnai Zion Medical Center","ror":"https://ror.org/01yvj7247","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113309"]}],"countries":["CA","IL"],"is_corresponding":false,"raw_author_name":"Irena Gannon","raw_affiliation_strings":["1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210113309","https://openalex.org/I174306211","https://openalex.org/I4394709267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042662203","display_name":"Adel Shalata","orcid":"https://orcid.org/0000-0001-5209-2072"},"institutions":[{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I4210113309","display_name":"Bnai Zion Medical Center","ror":"https://ror.org/01yvj7247","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113309"]},{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I4394709267","display_name":"Israel Institute","ror":"https://ror.org/00xfkzq83","country_code":null,"type":"nonprofit","lineage":["https://openalex.org/I4394709267"]}],"countries":["CA","IL"],"is_corresponding":false,"raw_author_name":"Adel Shalata","raw_affiliation_strings":["1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210113309","https://openalex.org/I174306211","https://openalex.org/I4394709267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111788432","display_name":"Zvi Borochowitz","orcid":null},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I4210113309","display_name":"Bnai Zion Medical Center","ror":"https://ror.org/01yvj7247","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113309"]},{"id":"https://openalex.org/I4394709267","display_name":"Israel Institute","ror":"https://ror.org/00xfkzq83","country_code":null,"type":"nonprofit","lineage":["https://openalex.org/I4394709267"]}],"countries":["CA","IL"],"is_corresponding":false,"raw_author_name":"Zvi U. Borochowitz","raw_affiliation_strings":["1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210113309","https://openalex.org/I174306211","https://openalex.org/I4394709267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053651798","display_name":"Rina Dechter","orcid":null},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I4394709267","display_name":"Israel Institute","ror":"https://ror.org/00xfkzq83","country_code":null,"type":"nonprofit","lineage":["https://openalex.org/I4394709267"]},{"id":"https://openalex.org/I4210113309","display_name":"Bnai Zion Medical Center","ror":"https://ror.org/01yvj7247","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113309"]}],"countries":["CA","IL"],"is_corresponding":false,"raw_author_name":"Rina Dechter","raw_affiliation_strings":["1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210113309","https://openalex.org/I174306211","https://openalex.org/I4394709267"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086436790","display_name":"E. A. Thompson","orcid":"https://orcid.org/0000-0003-0198-7129"},"institutions":[{"id":"https://openalex.org/I4394709267","display_name":"Israel Institute","ror":"https://ror.org/00xfkzq83","country_code":null,"type":"nonprofit","lineage":["https://openalex.org/I4394709267"]},{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I4210113309","display_name":"Bnai Zion Medical Center","ror":"https://ror.org/01yvj7247","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113309"]}],"countries":["CA","IL"],"is_corresponding":false,"raw_author_name":"Elizabeth Thompson","raw_affiliation_strings":["1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210113309","https://openalex.org/I174306211","https://openalex.org/I4394709267"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000414827","display_name":"Dan Geiger","orcid":"https://orcid.org/0000-0001-9988-0199"},"institutions":[{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I4394709267","display_name":"Israel Institute","ror":"https://ror.org/00xfkzq83","country_code":null,"type":"nonprofit","lineage":["https://openalex.org/I4394709267"]},{"id":"https://openalex.org/I4210113309","display_name":"Bnai Zion Medical Center","ror":"https://ror.org/01yvj7247","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I4210113309"]},{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]}],"countries":["CA","IL"],"is_corresponding":false,"raw_author_name":"Dan Geiger","raw_affiliation_strings":["1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Technion-Israel Institute of Technology, Haifa 32000, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX 78712-0500, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA 92697-3435, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada K1S 0S1, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, 31048, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr 20200, Israel, 7Holy Family Hospital, Nazareth 16100, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel and 9Department of Statistics, University of Washington, Seattle, WA 98195-4322, USA","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210113309","https://openalex.org/I174306211","https://openalex.org/I4394709267"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5028616817"],"corresponding_institution_ids":["https://openalex.org/I153718931","https://openalex.org/I174306211","https://openalex.org/I4210113309","https://openalex.org/I4394709267"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":1.6213,"has_fulltext":false,"cited_by_count":51,"citation_normalized_percentile":{"value":0.84918589,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"29","issue":"2","first_page":"197","last_page":"205"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9912999868392944,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tag-snp","display_name":"Tag SNP","score":0.7613345980644226},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7537147402763367},{"id":"https://openalex.org/keywords/snp","display_name":"SNP","score":0.5558680295944214},{"id":"https://openalex.org/keywords/markov-chain-monte-carlo","display_name":"Markov chain Monte Carlo","score":0.5454164743423462},{"id":"https://openalex.org/keywords/workflow","display_name":"Workflow","score":0.5255362391471863},{"id":"https://openalex.org/keywords/linkage","display_name":"Linkage (software)","score":0.5247504711151123},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4696342945098877},{"id":"https://openalex.org/keywords/pedigree-chart","display_name":"Pedigree chart","score":0.41457870602607727},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.34469693899154663},{"id":"https://openalex.org/keywords/haplotype","display_name":"Haplotype","score":0.31061965227127075},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.2682042419910431},{"id":"https://openalex.org/keywords/bayesian-probability","display_name":"Bayesian probability","score":0.24939513206481934},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2156585156917572},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.20763644576072693},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.16813305020332336},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.14721372723579407}],"concepts":[{"id":"https://openalex.org/C55060382","wikidata":"https://www.wikidata.org/wiki/Q7675093","display_name":"Tag SNP","level":5,"score":0.7613345980644226},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7537147402763367},{"id":"https://openalex.org/C139275648","wikidata":"https://www.wikidata.org/wiki/Q17134011","display_name":"SNP","level":5,"score":0.5558680295944214},{"id":"https://openalex.org/C111350023","wikidata":"https://www.wikidata.org/wiki/Q1191869","display_name":"Markov chain Monte Carlo","level":3,"score":0.5454164743423462},{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.5255362391471863},{"id":"https://openalex.org/C31266012","wikidata":"https://www.wikidata.org/wiki/Q6554340","display_name":"Linkage (software)","level":3,"score":0.5247504711151123},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4696342945098877},{"id":"https://openalex.org/C22593422","wikidata":"https://www.wikidata.org/wiki/Q3242583","display_name":"Pedigree chart","level":3,"score":0.41457870602607727},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.34469693899154663},{"id":"https://openalex.org/C197754878","wikidata":"https://www.wikidata.org/wiki/Q80711","display_name":"Haplotype","level":4,"score":0.31061965227127075},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.2682042419910431},{"id":"https://openalex.org/C107673813","wikidata":"https://www.wikidata.org/wiki/Q812534","display_name":"Bayesian probability","level":2,"score":0.24939513206481934},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2156585156917572},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.20763644576072693},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.16813305020332336},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14721372723579407},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/bts658","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bts658","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/29/2/197/48890668/bioinformatics_29_2_197.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2876013","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3546794","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/bts658","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bts658","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/29/2/197/48890668/bioinformatics_29_2_197.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Partnerships for the goals","id":"https://metadata.un.org/sdg/17","score":0.44999998807907104}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2159531362.pdf","grobid_xml":"https://content.openalex.org/works/W2159531362.grobid-xml"},"referenced_works_count":86,"referenced_works":["https://openalex.org/W61781882","https://openalex.org/W1490046998","https://openalex.org/W1493774699","https://openalex.org/W1505442699","https://openalex.org/W1519466388","https://openalex.org/W1538524809","https://openalex.org/W1549470101","https://openalex.org/W1643869946","https://openalex.org/W1736116989","https://openalex.org/W1765369324","https://openalex.org/W1968105228","https://openalex.org/W1976929204","https://openalex.org/W1976934404","https://openalex.org/W1984508337","https://openalex.org/W1987295193","https://openalex.org/W1991311566","https://openalex.org/W1991897103","https://openalex.org/W1993063013","https://openalex.org/W1998158007","https://openalex.org/W2002688528","https://openalex.org/W2009463846","https://openalex.org/W2021421243","https://openalex.org/W2030308147","https://openalex.org/W2045587089","https://openalex.org/W2046790669","https://openalex.org/W2046996883","https://openalex.org/W2049960044","https://openalex.org/W2053114866","https://openalex.org/W2054017030","https://openalex.org/W2061596350","https://openalex.org/W2068815039","https://openalex.org/W2069717815","https://openalex.org/W2072070785","https://openalex.org/W2087145431","https://openalex.org/W2089221493","https://openalex.org/W2091798871","https://openalex.org/W2092922183","https://openalex.org/W2093223772","https://openalex.org/W2100069480","https://openalex.org/W2100583455","https://openalex.org/W2102580330","https://openalex.org/W2105306382","https://openalex.org/W2107732097","https://openalex.org/W2107871825","https://openalex.org/W2110418019","https://openalex.org/W2114408926","https://openalex.org/W2122003883","https://openalex.org/W2127497482","https://openalex.org/W2130717716","https://openalex.org/W2132257651","https://openalex.org/W2135046866","https://openalex.org/W2135194391","https://openalex.org/W2138221062","https://openalex.org/W2143744448","https://openalex.org/W2147148915","https://openalex.org/W2147248889","https://openalex.org/W2147387551","https://openalex.org/W2148534890","https://openalex.org/W2150722176","https://openalex.org/W2151224868","https://openalex.org/W2153025946","https://openalex.org/W2153806142","https://openalex.org/W2157699287","https://openalex.org/W2158875345","https://openalex.org/W2159824577","https://openalex.org/W2161409413","https://openalex.org/W2165952534","https://openalex.org/W2171111925","https://openalex.org/W2293840314","https://openalex.org/W2401124505","https://openalex.org/W2414609135","https://openalex.org/W2418553757","https://openalex.org/W2476978346","https://openalex.org/W2604607099","https://openalex.org/W4300942465","https://openalex.org/W4319590830","https://openalex.org/W4393367792","https://openalex.org/W6602571187","https://openalex.org/W6630799319","https://openalex.org/W6632240119","https://openalex.org/W6632816856","https://openalex.org/W6636864426","https://openalex.org/W6637803748","https://openalex.org/W6675437406","https://openalex.org/W6676126879","https://openalex.org/W6697217167"],"related_works":["https://openalex.org/W32690048","https://openalex.org/W1512256068","https://openalex.org/W2030726611","https://openalex.org/W2116742344","https://openalex.org/W2385131910","https://openalex.org/W2168919926","https://openalex.org/W2013739566","https://openalex.org/W2537403558","https://openalex.org/W2105612687","https://openalex.org/W2158049867"],"abstract_inverted_index":{"Abstract":[0],"Motivation:":[1],"The":[2,75,158,199,236],"use":[3],"of":[4,15,42,82,89,118,142,160,217],"dense":[5],"single":[6,94],"nucleotide":[7],"polymorphism":[8],"(SNP)":[9],"data":[10,58,65,85,120,253],"in":[11],"genetic":[12,203],"linkage":[13,40],"analysis":[14,41,59,86,104],"large":[16,219],"pedigrees":[17],"is":[18,150,163,189,229],"impeded":[19],"by":[20,128,166],"significant":[21],"technical,":[22],"methodological":[23],"and":[24,56,68,72,137,174],"computational":[25],"challenges.":[26],"Here":[27],"we":[28],"describe":[29],"Superlink-Online":[30,111,129,227],"SNP,":[31],"a":[32,47,93,190,215,218],"new":[33],"powerful":[34],"online":[35],"system":[36,76,201,212,237,246],"that":[37,205],"streamlines":[38],"the":[39,116,161,168,176,187,211,245],"SNP":[43,62,112,119,130,228],"data.":[44],"It":[45],"features":[46],"fully":[48],"integrated":[49],"flexible":[50],"processing":[51],"workflow":[52,188],"comprising":[53],"both":[54],"well-known":[55],"novel":[57,135,148,191],"tools,":[60],"including":[61],"clustering,":[63],"erroneous":[64],"filtering,":[66],"exact":[67,193],"approximate":[69,152],"LOD":[70],"calculations":[71],"maximum-likelihood":[73,197],"haplotyping.":[74,198],"draws":[77],"its":[78],"power":[79],"from":[80,244],"thousands":[81],"CPUs,":[83],"performing":[84],"tasks":[87],"orders":[88],"magnitude":[90],"faster":[91],"than":[92],"computer.":[95],"By":[96],"providing":[97],"an":[98],"intuitive":[99],"interface":[100],"to":[101,179],"sophisticated":[102],"state-of-the-art":[103],"tools":[105],"coupled":[106],"with":[107,223],"high":[108],"computing":[109],"capacity,":[110],"helps":[113],"geneticists":[114],"unleash":[115],"potential":[117],"for":[121,195,232],"detecting":[122],"disease":[123],"genes.":[124],"Results:":[125],"Computations":[126],"performed":[127],"are":[131,254],"automatically":[132],"parallelized":[133,192],"using":[134],"paradigms,":[136],"executed":[138],"on":[139,171],"unlimited":[140],"number":[141],"private":[143],"or":[144],"public":[145],"CPUs.":[146],"One":[147],"service":[149,185],"large-scale":[151],"Markov":[153],"Chain\u2013Monte":[154],"Carlo":[155],"(MCMC)":[156],"analysis.":[157],"accuracy":[159],"results":[162],"reliably":[164],"estimated":[165],"running":[167],"same":[169],"computation":[170],"multiple":[172],"CPUs":[173],"evaluating":[175],"Gelman\u2013Rubin":[177],"Score":[178],"set":[180],"aside":[181],"unreliable":[182],"results.":[183],"Another":[184],"within":[186],"algorithm":[194],"inferring":[196],"reported":[200],"enables":[202],"analyses":[204],"were":[206],"previously":[207],"infeasible.":[208],"We":[209],"demonstrate":[210],"capabilities":[213],"through":[214],"study":[216],"complex":[220],"pedigree":[221],"affected":[222],"metabolic":[224],"syndrome.":[225],"Availability:":[226],"freely":[230],"available":[231,255],"researchers":[233],"at":[234,256],"http://cbl-hap.cs.technion.ac.il/superlink-snp.":[235],"source":[238],"code":[239],"can":[240],"also":[241],"be":[242],"downloaded":[243],"website.":[247],"Contact:":[248],"omerw@cs.technion.ac.il":[249],"Supplementary":[250,252],"information:":[251],"Bioinformatics":[257],"online.":[258]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}