{"id":"https://openalex.org/W2158404603","doi":"https://doi.org/10.1093/bioinformatics/bts082","title":"Early immunologic correlates of HIV protection can be identified from computational analysis of complex multivariate T-cell flow cytometry assays","display_name":"Early immunologic correlates of HIV protection can be identified from computational analysis of complex multivariate T-cell flow cytometry assays","publication_year":2012,"publication_date":"2012-02-29","ids":{"openalex":"https://openalex.org/W2158404603","doi":"https://doi.org/10.1093/bioinformatics/bts082","mag":"2158404603","pmid":"https://pubmed.ncbi.nlm.nih.gov/22383736"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/bts082","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bts082","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/28/7/1009/48882045/bioinformatics_28_7_1009.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/28/7/1009/48882045/bioinformatics_28_7_1009.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031425035","display_name":"Nima Aghaeepour","orcid":"https://orcid.org/0000-0002-6117-8764"},"institutions":[{"id":"https://openalex.org/I1289530486","display_name":"BC Cancer Agency","ror":"https://ror.org/03sfybe47","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1289530486"]},{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210109318","display_name":"Michael Smith Health Research BC","ror":"https://ror.org/020x39229","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I4210109318"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Nima Aghaeepour","raw_affiliation_strings":["1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada","institution_ids":["https://openalex.org/I1289530486","https://openalex.org/I141945490","https://openalex.org/I2800363604","https://openalex.org/I4210109318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025059957","display_name":"Pratip K. Chattopadhyay","orcid":"https://orcid.org/0000-0002-5457-9666"},"institutions":[{"id":"https://openalex.org/I1289530486","display_name":"BC Cancer Agency","ror":"https://ror.org/03sfybe47","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1289530486"]},{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210109318","display_name":"Michael Smith Health Research BC","ror":"https://ror.org/020x39229","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I4210109318"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Pratip K. Chattopadhyay","raw_affiliation_strings":["1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada","institution_ids":["https://openalex.org/I1289530486","https://openalex.org/I141945490","https://openalex.org/I2800363604","https://openalex.org/I4210109318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110816758","display_name":"Anuradha Ganesan","orcid":null},"institutions":[{"id":"https://openalex.org/I1289530486","display_name":"BC Cancer Agency","ror":"https://ror.org/03sfybe47","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1289530486"]},{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210109318","display_name":"Michael Smith Health Research BC","ror":"https://ror.org/020x39229","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I4210109318"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Anuradha Ganesan","raw_affiliation_strings":["1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada","institution_ids":["https://openalex.org/I1289530486","https://openalex.org/I141945490","https://openalex.org/I2800363604","https://openalex.org/I4210109318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035078802","display_name":"Kieran O\u2019Neill","orcid":"https://orcid.org/0000-0001-7609-5905"},"institutions":[{"id":"https://openalex.org/I1289530486","display_name":"BC Cancer Agency","ror":"https://ror.org/03sfybe47","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1289530486"]},{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210109318","display_name":"Michael Smith Health Research BC","ror":"https://ror.org/020x39229","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I4210109318"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Kieran O'Neill","raw_affiliation_strings":["1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada","institution_ids":["https://openalex.org/I1289530486","https://openalex.org/I141945490","https://openalex.org/I2800363604","https://openalex.org/I4210109318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062228773","display_name":"Habil Zare","orcid":"https://orcid.org/0000-0001-5902-6238"},"institutions":[{"id":"https://openalex.org/I1289530486","display_name":"BC Cancer Agency","ror":"https://ror.org/03sfybe47","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1289530486"]},{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210109318","display_name":"Michael Smith Health Research BC","ror":"https://ror.org/020x39229","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I4210109318"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Habil Zare","raw_affiliation_strings":["1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada","institution_ids":["https://openalex.org/I1289530486","https://openalex.org/I141945490","https://openalex.org/I2800363604","https://openalex.org/I4210109318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023259879","display_name":"Adrin Jalali","orcid":null},"institutions":[{"id":"https://openalex.org/I1289530486","display_name":"BC Cancer Agency","ror":"https://ror.org/03sfybe47","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1289530486"]},{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210109318","display_name":"Michael Smith Health Research BC","ror":"https://ror.org/020x39229","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I4210109318"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Adrin Jalali","raw_affiliation_strings":["1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada","institution_ids":["https://openalex.org/I1289530486","https://openalex.org/I141945490","https://openalex.org/I2800363604","https://openalex.org/I4210109318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025342513","display_name":"Holger H. Hoos","orcid":"https://orcid.org/0000-0003-0629-0099"},"institutions":[{"id":"https://openalex.org/I1289530486","display_name":"BC Cancer Agency","ror":"https://ror.org/03sfybe47","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1289530486"]},{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210109318","display_name":"Michael Smith Health Research BC","ror":"https://ror.org/020x39229","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I4210109318"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Holger H. Hoos","raw_affiliation_strings":["1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada","institution_ids":["https://openalex.org/I1289530486","https://openalex.org/I141945490","https://openalex.org/I2800363604","https://openalex.org/I4210109318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090939942","display_name":"Mario Roederer","orcid":"https://orcid.org/0000-0001-7448-7040"},"institutions":[{"id":"https://openalex.org/I1289530486","display_name":"BC Cancer Agency","ror":"https://ror.org/03sfybe47","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1289530486"]},{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210109318","display_name":"Michael Smith Health Research BC","ror":"https://ror.org/020x39229","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I4210109318"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Mario Roederer","raw_affiliation_strings":["1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada","institution_ids":["https://openalex.org/I1289530486","https://openalex.org/I141945490","https://openalex.org/I2800363604","https://openalex.org/I4210109318"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035285628","display_name":"Ryan R. Brinkman","orcid":"https://orcid.org/0000-0002-9765-2990"},"institutions":[{"id":"https://openalex.org/I1289530486","display_name":"BC Cancer Agency","ror":"https://ror.org/03sfybe47","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1289530486"]},{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]},{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]},{"id":"https://openalex.org/I4210109318","display_name":"Michael Smith Health Research BC","ror":"https://ror.org/020x39229","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I4210109318"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Ryan R. Brinkman","raw_affiliation_strings":["1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, 2Vaccine Research Center, National Institute of Health, Bethesda, 3Walter Reed National Military Medical Center, Rockville, MD 20889, USA, 4Department of Computer Science, 5Department of Medical Genetics and 6CIHR/MSFHR Strategic Training Program in Bioinformatics for Health Research, University of British Columbia, Vancouver, BC V5Z 4S6, Canada","institution_ids":["https://openalex.org/I1289530486","https://openalex.org/I141945490","https://openalex.org/I2800363604","https://openalex.org/I4210109318"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":4.4798,"has_fulltext":true,"cited_by_count":72,"citation_normalized_percentile":{"value":0.95458001,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"28","issue":"7","first_page":"1009","last_page":"1016"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9373999834060669,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9373999834060669,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.03590000048279762,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.005900000222027302,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bioconductor","display_name":"Bioconductor","score":0.8949582576751709},{"id":"https://openalex.org/keywords/multivariate-statistics","display_name":"Multivariate statistics","score":0.6585513353347778},{"id":"https://openalex.org/keywords/multivariate-analysis","display_name":"Multivariate analysis","score":0.637336790561676},{"id":"https://openalex.org/keywords/flow-cytometry","display_name":"Flow cytometry","score":0.5915589332580566},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5862839221954346},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5650683641433716},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5270747542381287},{"id":"https://openalex.org/keywords/documentation","display_name":"Documentation","score":0.4825996160507202},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.37847796082496643},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3279005289077759},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.2827461361885071},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.1796901822090149},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.08287671208381653}],"concepts":[{"id":"https://openalex.org/C2779694297","wikidata":"https://www.wikidata.org/wiki/Q2888953","display_name":"Bioconductor","level":3,"score":0.8949582576751709},{"id":"https://openalex.org/C161584116","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate statistics","level":2,"score":0.6585513353347778},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.637336790561676},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.5915589332580566},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5862839221954346},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5650683641433716},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5270747542381287},{"id":"https://openalex.org/C56666940","wikidata":"https://www.wikidata.org/wiki/Q788790","display_name":"Documentation","level":2,"score":0.4825996160507202},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37847796082496643},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3279005289077759},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2827461361885071},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.1796901822090149},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08287671208381653},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/bts082","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bts082","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/28/7/1009/48882045/bioinformatics_28_7_1009.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:22383736","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22383736","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:europepmc.org:2608363","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3315712","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/bts082","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bts082","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/28/7/1009/48882045/bioinformatics_28_7_1009.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"No poverty","score":0.41999998688697815,"id":"https://metadata.un.org/sdg/1"}],"awards":[{"id":"https://openalex.org/G1453369218","display_name":null,"funder_award_id":"HSN261200800001E","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"},{"id":"https://openalex.org/G3596225420","display_name":null,"funder_award_id":"EB008400","funder_id":"https://openalex.org/F4320319965","funder_display_name":"Michael Smith Health Research BC"},{"id":"https://openalex.org/G3667057077","display_name":null,"funder_award_id":"HSN261200800001E","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4793338163","display_name":null,"funder_award_id":"R01 EB008400","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G551603443","display_name":null,"funder_award_id":"EB008400","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G5756171758","display_name":null,"funder_award_id":"HSN261200800001E","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G589725395","display_name":"The Statistical and Computational Analysis of Flow Cytometry Data","funder_award_id":"5r01eb008400-08","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6877527716","display_name":null,"funder_award_id":"EB008400","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G8749615092","display_name":null,"funder_award_id":"HSN261200800001E","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8838525055","display_name":null,"funder_award_id":"Z99 AI999999","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320314000","display_name":"Compute Canada","ror":"https://ror.org/03ty8yr27"},{"id":"https://openalex.org/F4320314005","display_name":"Western Canada Research Grid","ror":null},{"id":"https://openalex.org/F4320316894","display_name":"Vaccine Research Center","ror":null},{"id":"https://openalex.org/F4320319965","display_name":"Michael Smith Health Research BC","ror":"https://ror.org/020x39229"},{"id":"https://openalex.org/F4320322597","display_name":"Terry Fox Research Institute","ror":"https://ror.org/05vd00053"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332504","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386"},{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320333429","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651"},{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2158404603.pdf","grobid_xml":"https://content.openalex.org/works/W2158404603.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W19461481","https://openalex.org/W1497374306","https://openalex.org/W1538178305","https://openalex.org/W1591773746","https://openalex.org/W1600928734","https://openalex.org/W1627654352","https://openalex.org/W1753039009","https://openalex.org/W1757909678","https://openalex.org/W1941148137","https://openalex.org/W1974934611","https://openalex.org/W1981480494","https://openalex.org/W1983522216","https://openalex.org/W1984034984","https://openalex.org/W1984999783","https://openalex.org/W2002420618","https://openalex.org/W2008994596","https://openalex.org/W2010847848","https://openalex.org/W2024593848","https://openalex.org/W2024626836","https://openalex.org/W2025897582","https://openalex.org/W2027168511","https://openalex.org/W2054169201","https://openalex.org/W2056538898","https://openalex.org/W2059467017","https://openalex.org/W2065865339","https://openalex.org/W2072765827","https://openalex.org/W2081772552","https://openalex.org/W2082371334","https://openalex.org/W2101622558","https://openalex.org/W2113142309","https://openalex.org/W2114124472","https://openalex.org/W2114857761","https://openalex.org/W2116258000","https://openalex.org/W2117625122","https://openalex.org/W2143265231","https://openalex.org/W2150756255","https://openalex.org/W2156364173","https://openalex.org/W2160697532","https://openalex.org/W2167619535","https://openalex.org/W2169109107","https://openalex.org/W2324805613","https://openalex.org/W2612166593","https://openalex.org/W4231184784","https://openalex.org/W4285719527","https://openalex.org/W6677059569","https://openalex.org/W6677265930","https://openalex.org/W6701025152"],"related_works":["https://openalex.org/W2406638334","https://openalex.org/W40745829","https://openalex.org/W1978357124","https://openalex.org/W1974427739","https://openalex.org/W1578824628","https://openalex.org/W1570805059","https://openalex.org/W2032728545","https://openalex.org/W4318262572","https://openalex.org/W2036849593","https://openalex.org/W1978174651"],"abstract_inverted_index":{"MOTIVATION:":[0],"Polychromatic":[1],"flow":[2],"cytometry":[3],"(PFC),":[4],"has":[5,80],"enormous":[6],"power":[7],"as":[8,17,90],"a":[9,24,71,91,104,186],"tool":[10,93],"to":[11,139,164,207],"dissect":[12],"complex":[13,148,159],"immune":[14],"responses":[15],"(such":[16],"those":[18,120],"observed":[19],"in":[20,185],"HIV":[21,195],"disease)":[22],"at":[23,246],"single":[25],"cell":[26,53,112],"level.":[27],"However,":[28],"analysis":[29,46,174],"tools":[30],"are":[31,127,143,236,244],"severely":[32],"lacking.":[33],"Although":[34],"high-throughput":[35],"systems":[36],"allow":[37],"rapid":[38],"data":[39,45,243],"collection":[40],"from":[41,161],"large":[42,187],"cohorts,":[43],"manual":[44,218],"can":[47,55],"take":[48],"months.":[49],"Moreover,":[50],"identification":[51],"of":[52,64,74,78,88,116,118,182,193,211],"populations":[54],"be":[56,165],"subjective":[57],"and":[58,129,234],"analysts":[59],"rarely":[60],"examine":[61],"the":[62,65,76,86,140,147,151,180],"entirety":[63],"multidimensional":[66],"dataset":[67,149],"(focusing":[68],"instead":[69],"on":[70],"limited":[72],"number":[73],"subsets,":[75,119],"biology":[77],"which":[79,212],"usually":[81],"already":[82],"been":[83],"well-described).":[84],"Thus,":[85],"value":[87],"PFC":[89,162,191,225],"discovery":[92],"is":[94,175,228],"largely":[95],"wasted.":[96],"RESULTS:":[97],"To":[98],"address":[99],"this":[100,183],"problem,":[101],"we":[102,198],"developed":[103],"computational":[105],"approach":[106,184],"that":[107,121,135,203],"automatically":[108],"reveals":[109],"all":[110],"possible":[111],"subsets.":[113,156],"From":[114],"tens":[115],"thousands":[117],"correlate":[122],"strongly":[123,204],"with":[124],"clinical":[125,168],"outcome":[126,142],"selected":[128],"grouped.":[130],"Within":[131],"each":[132],"group,":[133],"markers":[134],"have":[136],"minimal":[137],"relevance":[138],"biological":[141],"removed,":[144],"thereby":[145],"distilling":[146],"into":[150,167],"simplest,":[152],"most":[153],"clinically":[154],"relevant":[155],"This":[157],"allows":[158],"information":[160],"studies":[163],"translated":[166],"or":[169],"resource-poor":[170],"settings,":[171],"where":[172,197],"multiparametric":[173],"less":[176],"feasible.":[177],"We":[178],"demonstrate":[179],"utility":[181],"(n=466),":[188],"retrospective,":[189],"14-parameter":[190],"study":[192],"early":[194],"infection,":[196],"identify":[199],"three":[200],"T-cell":[201],"subsets":[202],"predict":[205],"progression":[206],"AIDS":[208],"(only":[209],"one":[210],"was":[213],"identified":[214],"by":[215],"an":[216],"initial":[217],"analysis).":[219],"AVAILABILITY:":[220],"The":[221],"'flowType:":[222],"Phenotyping":[223],"Multivariate":[224],"Assays'":[226],"package":[227],"available":[229,237,245],"through":[230],"Bioconductor.":[231],"Additional":[232],"documentation":[233],"examples":[235],"at:":[238],"www.terryfoxlab.ca/flowsite/flowType/":[239],"SUPPLEMENTARY":[240],"INFORMATION:":[241],"Supplementary":[242],"Bioinformatics":[247],"online.":[248],"CONTACT:":[249],"rbrinkman@bccrc.ca.":[250]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":6}],"updated_date":"2026-08-06T08:24:18.245995","created_date":"2025-10-10T00:00:00"}
