{"id":"https://openalex.org/W2155518941","doi":"https://doi.org/10.1093/bioinformatics/btq667","title":"Toward an automatic method for extracting cancer- and other disease-related point mutations from the biomedical literature","display_name":"Toward an automatic method for extracting cancer- and other disease-related point mutations from the biomedical literature","publication_year":2010,"publication_date":"2010-12-07","ids":{"openalex":"https://openalex.org/W2155518941","doi":"https://doi.org/10.1093/bioinformatics/btq667","mag":"2155518941","pmid":"https://pubmed.ncbi.nlm.nih.gov/21138947"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btq667","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btq667","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3031038","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078152794","display_name":"Emily Doughty","orcid":null},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1335686170","display_name":"Center for Devices and Radiological Health","ror":"https://ror.org/007x9se63","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I1335686170"]},{"id":"https://openalex.org/I79272384","display_name":"University of Maryland, Baltimore County","ror":"https://ror.org/02qskvh78","country_code":"US","type":"education","lineage":["https://openalex.org/I79272384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emily Doughty","raw_affiliation_strings":["1 University of Maryland, Baltimore County, Baltimore, MD 21250, 2Division of Imaging and Applied Mathematics, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD 20993 and 3National Library of Medicine, Bethesda, MD 20894, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 University of Maryland, Baltimore County, Baltimore, MD 21250, 2Division of Imaging and Applied Mathematics, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD 20993 and 3National Library of Medicine, Bethesda, MD 20894, USA","institution_ids":["https://openalex.org/I1335686170","https://openalex.org/I79272384","https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037717293","display_name":"Attila Kert\u00e9sz\u2010Farkas","orcid":"https://orcid.org/0000-0001-8110-7253"},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1335686170","display_name":"Center for Devices and Radiological Health","ror":"https://ror.org/007x9se63","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I1335686170"]},{"id":"https://openalex.org/I79272384","display_name":"University of Maryland, Baltimore County","ror":"https://ror.org/02qskvh78","country_code":"US","type":"education","lineage":["https://openalex.org/I79272384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Attila Kertesz-Farkas","raw_affiliation_strings":["1 University of Maryland, Baltimore County, Baltimore, MD 21250, 2Division of Imaging and Applied Mathematics, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD 20993 and 3National Library of Medicine, Bethesda, MD 20894, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 University of Maryland, Baltimore County, Baltimore, MD 21250, 2Division of Imaging and Applied Mathematics, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD 20993 and 3National Library of Medicine, Bethesda, MD 20894, USA","institution_ids":["https://openalex.org/I1335686170","https://openalex.org/I79272384","https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073807945","display_name":"Olivier Bodenreider","orcid":"https://orcid.org/0000-0003-4769-4217"},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1335686170","display_name":"Center for Devices and Radiological Health","ror":"https://ror.org/007x9se63","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I1335686170"]},{"id":"https://openalex.org/I79272384","display_name":"University of Maryland, Baltimore County","ror":"https://ror.org/02qskvh78","country_code":"US","type":"education","lineage":["https://openalex.org/I79272384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olivier Bodenreider","raw_affiliation_strings":["1 University of Maryland, Baltimore County, Baltimore, MD 21250, 2Division of Imaging and Applied Mathematics, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD 20993 and 3National Library of Medicine, Bethesda, MD 20894, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 University of Maryland, Baltimore County, Baltimore, MD 21250, 2Division of Imaging and Applied Mathematics, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD 20993 and 3National Library of Medicine, Bethesda, MD 20894, USA","institution_ids":["https://openalex.org/I1335686170","https://openalex.org/I79272384","https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021771298","display_name":"Gary L. Thompson","orcid":"https://orcid.org/0000-0002-3201-4795"},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1335686170","display_name":"Center for Devices and Radiological Health","ror":"https://ror.org/007x9se63","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I1335686170"]},{"id":"https://openalex.org/I79272384","display_name":"University of Maryland, Baltimore County","ror":"https://ror.org/02qskvh78","country_code":"US","type":"education","lineage":["https://openalex.org/I79272384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary Thompson","raw_affiliation_strings":["1 University of Maryland, Baltimore County, Baltimore, MD 21250, 2Division of Imaging and Applied Mathematics, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD 20993 and 3National Library of Medicine, Bethesda, MD 20894, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 University of Maryland, Baltimore County, Baltimore, MD 21250, 2Division of Imaging and Applied Mathematics, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD 20993 and 3National Library of Medicine, Bethesda, MD 20894, USA","institution_ids":["https://openalex.org/I1335686170","https://openalex.org/I79272384","https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083323616","display_name":"Asa Adadey","orcid":null},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1335686170","display_name":"Center for Devices and Radiological Health","ror":"https://ror.org/007x9se63","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I1335686170"]},{"id":"https://openalex.org/I79272384","display_name":"University of Maryland, Baltimore County","ror":"https://ror.org/02qskvh78","country_code":"US","type":"education","lineage":["https://openalex.org/I79272384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Asa Adadey","raw_affiliation_strings":["1 University of Maryland, Baltimore County, Baltimore, MD 21250, 2Division of Imaging and Applied Mathematics, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD 20993 and 3National Library of Medicine, Bethesda, MD 20894, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 University of Maryland, Baltimore County, Baltimore, MD 21250, 2Division of Imaging and Applied Mathematics, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD 20993 and 3National Library of Medicine, Bethesda, MD 20894, USA","institution_ids":["https://openalex.org/I1335686170","https://openalex.org/I79272384","https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035694428","display_name":"Thomas Peterson","orcid":"https://orcid.org/0000-0002-9933-7556"},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1335686170","display_name":"Center for Devices and Radiological Health","ror":"https://ror.org/007x9se63","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I1335686170"]},{"id":"https://openalex.org/I79272384","display_name":"University of Maryland, Baltimore County","ror":"https://ror.org/02qskvh78","country_code":"US","type":"education","lineage":["https://openalex.org/I79272384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Peterson","raw_affiliation_strings":["1 University of Maryland, Baltimore County, Baltimore, MD 21250, 2Division of Imaging and Applied Mathematics, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD 20993 and 3National Library of Medicine, Bethesda, MD 20894, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 University of Maryland, Baltimore County, Baltimore, MD 21250, 2Division of Imaging and Applied Mathematics, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD 20993 and 3National Library of Medicine, Bethesda, MD 20894, USA","institution_ids":["https://openalex.org/I1335686170","https://openalex.org/I79272384","https://openalex.org/I1320320070"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013292761","display_name":"Maricel G. Kann","orcid":"https://orcid.org/0000-0003-0116-3883"},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1335686170","display_name":"Center for Devices and Radiological Health","ror":"https://ror.org/007x9se63","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070","https://openalex.org/I1335686170"]},{"id":"https://openalex.org/I79272384","display_name":"University of Maryland, Baltimore County","ror":"https://ror.org/02qskvh78","country_code":"US","type":"education","lineage":["https://openalex.org/I79272384"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Maricel G. Kann","raw_affiliation_strings":["1 University of Maryland, Baltimore County, Baltimore, MD 21250, 2Division of Imaging and Applied Mathematics, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD 20993 and 3National Library of Medicine, Bethesda, MD 20894, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 University of Maryland, Baltimore County, Baltimore, MD 21250, 2Division of Imaging and Applied Mathematics, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD 20993 and 3National Library of Medicine, Bethesda, MD 20894, USA","institution_ids":["https://openalex.org/I1335686170","https://openalex.org/I79272384","https://openalex.org/I1320320070"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5013292761"],"corresponding_institution_ids":["https://openalex.org/I1320320070","https://openalex.org/I1335686170","https://openalex.org/I79272384"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":1.361,"has_fulltext":false,"cited_by_count":112,"citation_normalized_percentile":{"value":0.80386027,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"27","issue":"3","first_page":"408","last_page":"415"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9685999751091003,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9685999751091003,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10028","display_name":"Topic Modeling","score":0.008799999952316284,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.005499999970197678,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/point-mutation","display_name":"Point mutation","score":0.621052622795105},{"id":"https://openalex.org/keywords/point","display_name":"Point (geometry)","score":0.5785542130470276},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.550344705581665},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4526970684528351},{"id":"https://openalex.org/keywords/mutation","display_name":"Mutation","score":0.4410099387168884},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.43255677819252014},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.37781819701194763},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.24718746542930603},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.22036507725715637},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.16270455718040466},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.16127550601959229}],"concepts":[{"id":"https://openalex.org/C176944494","wikidata":"https://www.wikidata.org/wiki/Q1415380","display_name":"Point mutation","level":4,"score":0.621052622795105},{"id":"https://openalex.org/C28719098","wikidata":"https://www.wikidata.org/wiki/Q44946","display_name":"Point (geometry)","level":2,"score":0.5785542130470276},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.550344705581665},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4526970684528351},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.4410099387168884},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.43255677819252014},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.37781819701194763},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.24718746542930603},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22036507725715637},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.16270455718040466},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16127550601959229},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011642","descriptor_name":"Publications","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011642","descriptor_name":"Publications","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011642","descriptor_name":"Publications","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011642","descriptor_name":"Publications","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017354","descriptor_name":"Point Mutation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017354","descriptor_name":"Point Mutation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017354","descriptor_name":"Point Mutation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017354","descriptor_name":"Point Mutation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btq667","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btq667","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:21138947","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21138947","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:3031038","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3031038","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3031038","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3031038","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"},"sustainable_development_goals":[{"score":0.4399999976158142,"id":"https://metadata.un.org/sdg/4","display_name":"Quality Education"}],"awards":[{"id":"https://openalex.org/G200805936","display_name":null,"funder_award_id":"1K22CA143148","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7174641041","display_name":null,"funder_award_id":"R01LM009722","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320308963","display_name":"Oak Ridge Associated Universities","ror":"https://ror.org/0526p1y61"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337372","display_name":"U.S. National Library of Medicine","ror":"https://ror.org/0060t0j89"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1534402964","https://openalex.org/W1550258693","https://openalex.org/W1553529581","https://openalex.org/W1974999557","https://openalex.org/W1978661319","https://openalex.org/W1984437174","https://openalex.org/W2018740767","https://openalex.org/W2033853342","https://openalex.org/W2039612385","https://openalex.org/W2042127857","https://openalex.org/W2048501271","https://openalex.org/W2059044388","https://openalex.org/W2065174899","https://openalex.org/W2102777243","https://openalex.org/W2107005506","https://openalex.org/W2107903949","https://openalex.org/W2115259143","https://openalex.org/W2122732537","https://openalex.org/W2123400343","https://openalex.org/W2123439964","https://openalex.org/W2131285447","https://openalex.org/W2134937886","https://openalex.org/W2144001613","https://openalex.org/W2146954401","https://openalex.org/W2148853951","https://openalex.org/W2156443053","https://openalex.org/W2157140935","https://openalex.org/W2157272674","https://openalex.org/W2159583324","https://openalex.org/W2162629891","https://openalex.org/W2170407972","https://openalex.org/W4212865600","https://openalex.org/W4292141786","https://openalex.org/W6632766574","https://openalex.org/W6675914680"],"related_works":["https://openalex.org/W2160983714","https://openalex.org/W2186113122","https://openalex.org/W2550943714","https://openalex.org/W3212350425","https://openalex.org/W2388007221","https://openalex.org/W2511508046","https://openalex.org/W2363458739","https://openalex.org/W2028961943","https://openalex.org/W2375287167","https://openalex.org/W1994083192"],"abstract_inverted_index":{"MOTIVATION:":[0],"A":[1],"major":[2],"goal":[3],"of":[4,23,58,79,134,183,191,235,262],"biomedical":[5,33],"research":[6],"in":[7,31,35,62,137,219,232,258],"personalized":[8],"medicine":[9],"is":[10,255],"to":[11,43,66,83,96,154,160,173,202,205],"find":[12],"relationships":[13],"between":[14],"mutations":[15,61,80,85,99,199,237],"and":[16,38,47,69,86,127,157,197,207,240],"their":[17,87],"corresponding":[18],"disease":[19,60],"phenotypes.":[20],"However,":[21],"most":[22],"the":[24,32,40,56,77,123,135,147,180,189,220,233],"disease-related":[25],"mutational":[26,125],"data":[27],"are":[28,211],"currently":[29,213],"buried":[30],"literature":[34],"textual":[36],"form":[37],"lack":[39],"necessary":[41],"structure":[42],"allow":[44],"easy":[45],"retrieval":[46,226],"visualization.":[48],"We":[49,75,90,116,163,194,242],"introduce":[50],"a":[51,140,229],"high-throughput":[52,168],"computational":[53],"method":[54,178,247],"for":[55,121,149,215,238],"identification":[57],"relevant":[59],"PubMed":[63],"abstracts":[64],"applied":[65],"prostate":[67],"(PCa)":[68,156],"breast":[70],"cancer":[71,217],"(BCa)":[72],"mutations.":[73,193],"RESULTS:":[74],"developed":[76],"extractor":[78],"(EMU)":[81],"tool":[82,95],"identify":[84],"associated":[88],"genes.":[89],"benchmarked":[91,118],"EMU":[92],"against":[93],"MutationFinder--a":[94],"extract":[97],"point":[98],"from":[100,152,158,250],"text.":[101],"Our":[102,177],"results":[103],"show":[104,131,165,244],"that":[105,132,150,166,210,245],"both":[106],"methods":[107],"achieve":[108],"comparable":[109],"performance":[110,120,227],"on":[111,143],"two":[112],"manually":[113,200],"curated":[114],"datasets.":[115],"also":[117,164],"EMU's":[119,225],"extracting":[122],"complete":[124],"information":[126],"phenotype.":[128],"Remarkably,":[129],"we":[130],"one":[133],"steps":[136],"our":[138,246],"approach,":[139],"filter":[141],"based":[142],"sequence":[144],"analysis,":[145],"increases":[146],"precision":[148],"task":[151],"0.34":[153],"0.59":[155],"0.39":[159],"0.61":[161],"(BCa).":[162],"this":[167],"approach":[169],"can":[170,248],"be":[171,203],"extended":[172],"other":[174],"diseases.":[175],"DISCUSSION:":[176],"improves":[179],"current":[181],"status":[182],"disease-mutation":[184],"databases":[185],"by":[186],"significantly":[187],"increasing":[188],"number":[190,234],"annotated":[192,214,236],"found":[195],"51":[196],"128":[198],"verified":[201],"related":[204],"PCa":[206,239],"Bca,":[208],"respectively,":[209],"not":[212],"these":[216],"types":[218],"OMIM":[221],"or":[222],"Swiss-Prot":[223],"databases.":[224],"represents":[228],"2-fold":[230],"improvement":[231],"BCa.":[241],"further":[243],"benefit":[249],"full-text":[251,263],"analysis":[252],"once":[253],"there":[254],"an":[256],"increase":[257],"Open":[259],"Access":[260],"availability":[261],"articles.":[264],"AVAILABILITY:":[265],"Freely":[266],"available":[267],"at:":[268],"http://bioinf.umbc.edu/EMU/ftp.":[269]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":14},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":17},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":6}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}