{"id":"https://openalex.org/W2128103604","doi":"https://doi.org/10.1093/bioinformatics/btq553","title":"A statistical framework for Illumina DNA methylation arrays","display_name":"A statistical framework for Illumina DNA methylation arrays","publication_year":2010,"publication_date":"2010-09-29","ids":{"openalex":"https://openalex.org/W2128103604","doi":"https://doi.org/10.1093/bioinformatics/btq553","mag":"2128103604","pmid":"https://pubmed.ncbi.nlm.nih.gov/20880956"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btq553","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btq553","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/22/2849/16896780/btq553.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/26/22/2849/16896780/btq553.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055070977","display_name":"Pei Fen Kuan","orcid":"https://orcid.org/0000-0001-7861-916X"},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Pei Fen Kuan","raw_affiliation_strings":["1 Department of Biostatistics, 2Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, 3Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792 and 4Division of Biostatistics, University of Minnesota, Minneapolis, MN 55455, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Biostatistics, 2Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, 3Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792 and 4Division of Biostatistics, University of Minnesota, Minneapolis, MN 55455, USA","institution_ids":["https://openalex.org/I135310074","https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035250524","display_name":"Sijian Wang","orcid":"https://orcid.org/0000-0002-7094-2816"},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sijian Wang","raw_affiliation_strings":["1 Department of Biostatistics, 2Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, 3Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792 and 4Division of Biostatistics, University of Minnesota, Minneapolis, MN 55455, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Biostatistics, 2Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, 3Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792 and 4Division of Biostatistics, University of Minnesota, Minneapolis, MN 55455, USA","institution_ids":["https://openalex.org/I135310074","https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101860855","display_name":"Xin Zhou","orcid":"https://orcid.org/0000-0003-2238-2890"},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xin Zhou","raw_affiliation_strings":["1 Department of Biostatistics, 2Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, 3Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792 and 4Division of Biostatistics, University of Minnesota, Minneapolis, MN 55455, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Biostatistics, 2Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, 3Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792 and 4Division of Biostatistics, University of Minnesota, Minneapolis, MN 55455, USA","institution_ids":["https://openalex.org/I135310074","https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004584518","display_name":"Haitao Chu","orcid":"https://orcid.org/0000-0003-0932-598X"},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haitao Chu","raw_affiliation_strings":["1 Department of Biostatistics, 2Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, 3Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792 and 4Division of Biostatistics, University of Minnesota, Minneapolis, MN 55455, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Biostatistics, 2Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, 3Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792 and 4Division of Biostatistics, University of Minnesota, Minneapolis, MN 55455, USA","institution_ids":["https://openalex.org/I135310074","https://openalex.org/I130238516"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5055070977"],"corresponding_institution_ids":["https://openalex.org/I130238516","https://openalex.org/I135310074"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":16.3231,"has_fulltext":true,"cited_by_count":96,"citation_normalized_percentile":{"value":0.99158361,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"26","issue":"22","first_page":"2849","last_page":"2855"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":0.9940000176429749,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":0.9940000176429749,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9926000237464905,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9908999800682068,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.6109821796417236},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5477421283721924},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5039574503898621},{"id":"https://openalex.org/keywords/illumina-dye-sequencing","display_name":"Illumina dye sequencing","score":0.46239030361175537},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4529811143875122},{"id":"https://openalex.org/keywords/methylation","display_name":"Methylation","score":0.433192640542984},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.31037503480911255},{"id":"https://openalex.org/keywords/dna-sequencing","display_name":"DNA sequencing","score":0.2929003834724426},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.18749529123306274},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.08030867576599121}],"concepts":[{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.6109821796417236},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5477421283721924},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5039574503898621},{"id":"https://openalex.org/C106337198","wikidata":"https://www.wikidata.org/wiki/Q13564012","display_name":"Illumina dye sequencing","level":4,"score":0.46239030361175537},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4529811143875122},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.433192640542984},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.31037503480911255},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.2929003834724426},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18749529123306274},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.08030867576599121}],"mesh":[{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btq553","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btq553","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/22/2849/16896780/btq553.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:20880956","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20880956","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:3025715","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3025715","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btq553","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btq553","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/22/2849/16896780/btq553.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G5626962992","display_name":null,"funder_award_id":"R21CA134368","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6535059489","display_name":null,"funder_award_id":"P30-CA16086","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8696571978","display_name":null,"funder_award_id":"CA16086","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320306141","display_name":"Susan G. Komen for the Cure","ror":"https://ror.org/02nadbe75"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2128103604.pdf","grobid_xml":"https://content.openalex.org/works/W2128103604.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W1493454437","https://openalex.org/W1972985519","https://openalex.org/W1979674827","https://openalex.org/W1980681096","https://openalex.org/W1987971958","https://openalex.org/W1989503398","https://openalex.org/W2006641400","https://openalex.org/W2011832962","https://openalex.org/W2014793428","https://openalex.org/W2017818759","https://openalex.org/W2021660003","https://openalex.org/W2027102338","https://openalex.org/W2029197798","https://openalex.org/W2074746593","https://openalex.org/W2077359776","https://openalex.org/W2096715243","https://openalex.org/W2101214870","https://openalex.org/W2105324766","https://openalex.org/W2105717378","https://openalex.org/W2107776519","https://openalex.org/W2108435369","https://openalex.org/W2110065044","https://openalex.org/W2118250684","https://openalex.org/W2121127642","https://openalex.org/W2148405421","https://openalex.org/W2148521032","https://openalex.org/W2154906308","https://openalex.org/W2156922349","https://openalex.org/W2158312327","https://openalex.org/W2159732573","https://openalex.org/W2160583089","https://openalex.org/W2168850910","https://openalex.org/W2169012810","https://openalex.org/W2999729612","https://openalex.org/W4252676770","https://openalex.org/W6676358527"],"related_works":["https://openalex.org/W1455488868","https://openalex.org/W2902329290","https://openalex.org/W2052355316","https://openalex.org/W2046964473","https://openalex.org/W2107880877","https://openalex.org/W2151182744","https://openalex.org/W2024490794","https://openalex.org/W2221018455","https://openalex.org/W1998349112","https://openalex.org/W2054863651"],"abstract_inverted_index":{"R":[0],"package":[1],"LumiWCluster":[2],"can":[3],"be":[4],"downloaded":[5],"from":[6],"http://www.unc.edu/\u223cpfkuan/LumiWCluster.":[7]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":13},{"year":2013,"cited_by_count":20},{"year":2012,"cited_by_count":7}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}