{"id":"https://openalex.org/W2100367110","doi":"https://doi.org/10.1093/bioinformatics/btq432","title":"proTF: a comprehensive data and phylogenomics resource for prokaryotic transcription factors","display_name":"proTF: a comprehensive data and phylogenomics resource for prokaryotic transcription factors","publication_year":2010,"publication_date":"2010-07-27","ids":{"openalex":"https://openalex.org/W2100367110","doi":"https://doi.org/10.1093/bioinformatics/btq432","mag":"2100367110","pmid":"https://pubmed.ncbi.nlm.nih.gov/20663847"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btq432","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btq432","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/19/2493/48856078/bioinformatics_26_19_2493.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/26/19/2493/48856078/bioinformatics_26_19_2493.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102787936","display_name":"Jie Bai","orcid":"https://orcid.org/0000-0003-3839-5450"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Bai","raw_affiliation_strings":["1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I76130692","https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101760487","display_name":"Junrong Wang","orcid":"https://orcid.org/0000-0001-7430-9308"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junrong Wang","raw_affiliation_strings":["1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I76130692","https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020460652","display_name":"Feng Xue","orcid":"https://orcid.org/0000-0002-5058-5735"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feng Xue","raw_affiliation_strings":["1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I76130692","https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023138112","display_name":"Jingsong Li","orcid":"https://orcid.org/0000-0002-1064-637X"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingsong Li","raw_affiliation_strings":["1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I76130692","https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077772465","display_name":"Lijing Bu","orcid":"https://orcid.org/0000-0001-8625-2732"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lijing Bu","raw_affiliation_strings":["1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I76130692","https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109228206","display_name":"Junming Hu","orcid":"https://orcid.org/0000-0002-6503-7491"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junming Hu","raw_affiliation_strings":["1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I76130692","https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042922014","display_name":"Gang Xu","orcid":"https://orcid.org/0000-0002-0758-9693"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Gang Xu","raw_affiliation_strings":["1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I76130692","https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079596808","display_name":"Qiyu Bao","orcid":"https://orcid.org/0000-0002-9550-8266"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiyu Bao","raw_affiliation_strings":["1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I76130692","https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022141624","display_name":"Guoping Zhao","orcid":"https://orcid.org/0000-0002-7621-6620"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guoping Zhao","raw_affiliation_strings":["1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I76130692","https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101943273","display_name":"Xiaoming Ding","orcid":"https://orcid.org/0000-0002-7939-8837"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoming Ding","raw_affiliation_strings":["1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I76130692","https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101895910","display_name":"Jie Yan","orcid":"https://orcid.org/0009-0000-7991-7900"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Yan","raw_affiliation_strings":["1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I76130692","https://openalex.org/I24943067"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027650060","display_name":"Jinyu Wu","orcid":"https://orcid.org/0000-0001-5476-301X"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinyu Wu","raw_affiliation_strings":["1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Institute of Genomic Medicine/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou 325035, 2Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, 3Maternal and Child Health Hospital of Wenling, Wenling 317500 and 4Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I76130692","https://openalex.org/I24943067"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":12,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.1361,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.54924819,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"26","issue":"19","first_page":"2493","last_page":"2495"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.8431000113487244,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.8431000113487244,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.04179999977350235,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.03629999980330467,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phylogenomics","display_name":"Phylogenomics","score":0.9178813695907593},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.6361052393913269},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5853523015975952},{"id":"https://openalex.org/keywords/transcription-factor","display_name":"Transcription factor","score":0.5267999768257141},{"id":"https://openalex.org/keywords/resource","display_name":"Resource (disambiguation)","score":0.513568639755249},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.494895875453949},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.4773438274860382},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.44739875197410583},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.43072229623794556},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.33431774377822876},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.29186075925827026},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2643806040287018},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.22078445553779602},{"id":"https://openalex.org/keywords/phylogenetics","display_name":"Phylogenetics","score":0.21997720003128052}],"concepts":[{"id":"https://openalex.org/C70343354","wikidata":"https://www.wikidata.org/wiki/Q3381973","display_name":"Phylogenomics","level":5,"score":0.9178813695907593},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.6361052393913269},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5853523015975952},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5267999768257141},{"id":"https://openalex.org/C206345919","wikidata":"https://www.wikidata.org/wiki/Q20380951","display_name":"Resource (disambiguation)","level":2,"score":0.513568639755249},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.494895875453949},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4773438274860382},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.44739875197410583},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.43072229623794556},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.33431774377822876},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.29186075925827026},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2643806040287018},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.22078445553779602},{"id":"https://openalex.org/C90132467","wikidata":"https://www.wikidata.org/wiki/Q171184","display_name":"Phylogenetics","level":3,"score":0.21997720003128052},{"id":"https://openalex.org/C44465124","wikidata":"https://www.wikidata.org/wiki/Q713623","display_name":"Clade","level":4,"score":0.0},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019843","descriptor_name":"Archaeal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019843","descriptor_name":"Archaeal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019843","descriptor_name":"Archaeal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019843","descriptor_name":"Archaeal Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019843","descriptor_name":"Archaeal Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019843","descriptor_name":"Archaeal Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btq432","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btq432","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/19/2493/48856078/bioinformatics_26_19_2493.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:20663847","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20663847","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btq432","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btq432","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/19/2493/48856078/bioinformatics_26_19_2493.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2100367110.pdf"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W1547075801","https://openalex.org/W1972389369","https://openalex.org/W1999309464","https://openalex.org/W2022323886","https://openalex.org/W2026611608","https://openalex.org/W2042860668","https://openalex.org/W2061674320","https://openalex.org/W2065427389","https://openalex.org/W2070072684","https://openalex.org/W2085063163","https://openalex.org/W2098359498","https://openalex.org/W2101292724","https://openalex.org/W2105389823","https://openalex.org/W2107522712","https://openalex.org/W2108638877","https://openalex.org/W2111148192","https://openalex.org/W2116363471","https://openalex.org/W2118640842","https://openalex.org/W2121470635","https://openalex.org/W2129692583","https://openalex.org/W2136487066","https://openalex.org/W2137993400","https://openalex.org/W2157924605","https://openalex.org/W2161511344","https://openalex.org/W2171480318","https://openalex.org/W2171546784"],"related_works":["https://openalex.org/W2380915035","https://openalex.org/W2298047311","https://openalex.org/W4242909373","https://openalex.org/W2361861616","https://openalex.org/W1997697005","https://openalex.org/W2308248996","https://openalex.org/W2263699433","https://openalex.org/W2377979023","https://openalex.org/W2218034408","https://openalex.org/W2149299298"],"abstract_inverted_index":{"UNLABELLED:":[0],"Investigation":[1],"of":[2,7,102,115],"transcription":[3],"factors":[4],"(TFs)":[5],"is":[6,25],"extreme":[8],"significance":[9],"for":[10,38,68,105,135],"gleaning":[11],"more":[12],"information":[13],"about":[14],"the":[15,18,81,91,112,123,141],"mechanisms":[16],"underlying":[17],"dynamic":[19],"transcriptional":[20,137],"regulatory":[21,138],"network.":[22],"Herein,":[23],"proTF":[24,120],"constructed":[26],"to":[27,84,89,110,122],"serve":[28],"as":[29,80],"a":[30,100,132],"comprehensive":[31],"data":[32,93],"resource":[33,134],"and":[34,58,64,94,98],"phylogenomics":[35,106],"analysis":[36,107],"platform":[37],"prokaryotic":[39,74,124,136],"TFs.":[40,117],"It":[41],"has":[42],"many":[43],"prominent":[44],"characteristics:":[45],"(i)":[46],"detailed":[47],"annotation":[48],"information,":[49],"including":[50],"basic":[51,82],"sequence":[52,56,59],"features,":[53],"domain":[54],"organization,":[55],"homolog":[57],"composition,":[60],"was":[61,78],"extensively":[62],"collected,":[63],"then":[65],"visually":[66],"displayed":[67],"each":[69],"TF":[70],"entry":[71],"in":[72,140],"all":[73],"genomes;":[75],"(ii)":[76],"workset":[77],"employed":[79],"frame":[83],"provide":[85],"an":[86],"efficient":[87],"way":[88],"organize":[90],"retrieved":[92],"save":[95],"intermediate":[96],"records;":[97],"(iii)":[99],"number":[101],"elaborated":[103],"tools":[104],"were":[108],"implemented":[109],"investigate":[111],"evolutionary":[113],"roles":[114],"specific":[116],"In":[118],"conclusion,":[119],"dedicates":[121],"TFs":[125],"with":[126],"integrated":[127],"multi-function,":[128],"which":[129],"will":[130],"become":[131],"valuable":[133],"network":[139],"post-genomic":[142],"era.":[143],"AVAILABILITY:":[144],"http://centre.bioinformatics.zj.cn/proTF.":[145]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}