{"id":"https://openalex.org/W2137786443","doi":"https://doi.org/10.1093/bioinformatics/btq285","title":"DARNED: a DAtabase of RNa EDiting in humans","display_name":"DARNED: a DAtabase of RNa EDiting in humans","publication_year":2010,"publication_date":"2010-06-14","ids":{"openalex":"https://openalex.org/W2137786443","doi":"https://doi.org/10.1093/bioinformatics/btq285","mag":"2137786443","pmid":"https://pubmed.ncbi.nlm.nih.gov/20547637"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btq285","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btq285","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/14/1772/48852622/bioinformatics_26_14_1772.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/26/14/1772/48852622/bioinformatics_26_14_1772.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051578652","display_name":"Anmol Kiran","orcid":"https://orcid.org/0000-0003-2680-2303"},"institutions":[{"id":"https://openalex.org/I27577105","display_name":"University College Cork","ror":"https://ror.org/03265fv13","country_code":"IE","type":"education","lineage":["https://openalex.org/I27577105"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Anmol Kiran","raw_affiliation_strings":["Biochemistry Department, University College Cork, Ireland","Biochemistry Department, University College, Cork, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Department, University College Cork, Ireland","institution_ids":["https://openalex.org/I27577105"]},{"raw_affiliation_string":"Biochemistry Department, University College, Cork, Ireland","institution_ids":["https://openalex.org/I27577105"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047187282","display_name":"Pavel V. Baranov","orcid":"https://orcid.org/0000-0001-9017-0270"},"institutions":[{"id":"https://openalex.org/I27577105","display_name":"University College Cork","ror":"https://ror.org/03265fv13","country_code":"IE","type":"education","lineage":["https://openalex.org/I27577105"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Pavel V. Baranov","raw_affiliation_strings":["Biochemistry Department, University College Cork, Ireland","Biochemistry Department, University College, Cork, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Department, University College Cork, Ireland","institution_ids":["https://openalex.org/I27577105"]},{"raw_affiliation_string":"Biochemistry Department, University College, Cork, Ireland","institution_ids":["https://openalex.org/I27577105"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":7.3514,"has_fulltext":false,"cited_by_count":250,"citation_normalized_percentile":{"value":0.98012422,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"26","issue":"14","first_page":"1772","last_page":"1776"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12610","display_name":"RNA regulation and disease","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12610","display_name":"RNA regulation and disease","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rna-editing","display_name":"RNA editing","score":0.8619110584259033},{"id":"https://openalex.org/keywords/ensembl","display_name":"Ensembl","score":0.7775030136108398},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.7384582161903381},{"id":"https://openalex.org/keywords/intron","display_name":"Intron","score":0.5954769253730774},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5152068734169006},{"id":"https://openalex.org/keywords/genome-browser","display_name":"Genome browser","score":0.5086454153060913},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.49199768900871277},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.4162023961544037},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.3879151940345764},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.37656715512275696},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.33321139216423035},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.3255837857723236},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.29273784160614014}],"concepts":[{"id":"https://openalex.org/C21786251","wikidata":"https://www.wikidata.org/wiki/Q14886350","display_name":"RNA editing","level":4,"score":0.8619110584259033},{"id":"https://openalex.org/C141674004","wikidata":"https://www.wikidata.org/wiki/Q1344256","display_name":"Ensembl","level":5,"score":0.7775030136108398},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.7384582161903381},{"id":"https://openalex.org/C94671646","wikidata":"https://www.wikidata.org/wiki/Q207551","display_name":"Intron","level":3,"score":0.5954769253730774},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5152068734169006},{"id":"https://openalex.org/C2781148417","wikidata":"https://www.wikidata.org/wiki/Q5533486","display_name":"Genome browser","level":5,"score":0.5086454153060913},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49199768900871277},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4162023961544037},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.3879151940345764},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.37656715512275696},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.33321139216423035},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.3255837857723236},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.29273784160614014}],"mesh":[{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017393","descriptor_name":"RNA Editing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017393","descriptor_name":"RNA Editing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017393","descriptor_name":"RNA Editing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btq285","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btq285","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/14/1772/48852622/bioinformatics_26_14_1772.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:20547637","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20547637","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.840.3045","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.840.3045","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://bioinformatics.oxfordjournals.org/content/early/2010/06/14/bioinformatics.btq285.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btq285","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btq285","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/14/1772/48852622/bioinformatics_26_14_1772.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2137786443.pdf"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W1562307516","https://openalex.org/W1680720482","https://openalex.org/W1966933803","https://openalex.org/W1977627012","https://openalex.org/W1981509058","https://openalex.org/W1985317176","https://openalex.org/W1990478192","https://openalex.org/W1999086784","https://openalex.org/W2008172284","https://openalex.org/W2028423947","https://openalex.org/W2038981350","https://openalex.org/W2043724929","https://openalex.org/W2048984862","https://openalex.org/W2062714021","https://openalex.org/W2065163203","https://openalex.org/W2065881772","https://openalex.org/W2071302974","https://openalex.org/W2071856442","https://openalex.org/W2072016877","https://openalex.org/W2072498081","https://openalex.org/W2076961967","https://openalex.org/W2100984579","https://openalex.org/W2107426021","https://openalex.org/W2107534434","https://openalex.org/W2112192177","https://openalex.org/W2116418400","https://openalex.org/W2116660130","https://openalex.org/W2122732537","https://openalex.org/W2127640118","https://openalex.org/W2131959860","https://openalex.org/W2134017678","https://openalex.org/W2136145671","https://openalex.org/W2137015675","https://openalex.org/W2141169899","https://openalex.org/W2141499646","https://openalex.org/W2141923234","https://openalex.org/W2148203455","https://openalex.org/W2153240048","https://openalex.org/W2154360830","https://openalex.org/W2167018866","https://openalex.org/W2171580148","https://openalex.org/W2616754551","https://openalex.org/W2916408032","https://openalex.org/W3098298073","https://openalex.org/W3102334290","https://openalex.org/W4210430020","https://openalex.org/W4293196852","https://openalex.org/W6679594703","https://openalex.org/W6842402754"],"related_works":["https://openalex.org/W2462807523","https://openalex.org/W2139297998","https://openalex.org/W2096403311","https://openalex.org/W2804921183","https://openalex.org/W4384561511","https://openalex.org/W2041335525","https://openalex.org/W2109717569","https://openalex.org/W2023988982","https://openalex.org/W2039352533","https://openalex.org/W3175399373"],"abstract_inverted_index":{"MOTIVATION:":[0],"RNA":[1,16,28,52,83,85,112,116,139,156,167,176,202,243],"editing":[2,29,53,86,157,168,203,244],"is":[3,7,162,257],"a":[4,24,65,129,171],"phenomenon,":[5],"which":[6],"responsible":[8],"for":[9,170,238,246,252],"the":[10,48,91,99,187,247],"alteration":[11],"of":[12,27,70,98,131,189,201,206,249],"particular":[13],"nucleotides":[14],"in":[15,31,138,217,223],"sequences":[17],"relative":[18],"to":[19,59,77,82,111,165],"their":[20,134],"genomic":[21,132,197],"templates.":[22],"Recently,":[23],"large":[25],"number":[26,188],"instances":[30],"humans":[32],"have":[33],"been":[34,159,236],"identified":[35],"using":[36,128,178],"bioinformatic":[37],"screens":[38],"and":[39,57,146,150,196,204,219,245],"high-throughput":[40],"experimental":[41],"investigations":[42],"utilizing":[43],"next-generation":[44],"sequencing":[45],"technologies.":[46],"However,":[47],"available":[49,78],"data":[50,80,124,213,227],"on":[51,90,103,186,242],"are":[54,88],"not":[55],"uniform":[56],"difficult":[58],"access.":[60],"RESULTS:":[61],"Here,":[62],"we":[63],"describe":[64],"new":[66],"database":[67,100],"DARNED":[68,234,256],"(DAtabase":[69],"RNa":[71],"EDiting)":[72],"that":[73,114],"provides":[74],"centralized":[75],"access":[76],"published":[79],"related":[81],"editing.":[84],"locations":[87,113],"mapped":[89],"reference":[92],"human":[93,107],"genome.":[94],"The":[95,123],"current":[96],"release":[97],"contains":[101],"information":[102,151,169,185,241],"approximately":[104],"42":[105],"000":[106],"genome":[108,221,232],"coordinates":[109],"corresponding":[110,135,179],"undergo":[115],"editing,":[117],"mostly":[118],"involving":[119],"adenosine-to-inosine":[120],"(A-to-I)":[121],"substitutions.":[122],"can":[125,214],"be":[126,215],"queried":[127],"range":[130],"coordinates,":[133],"functional":[136,199],"localization":[137,200],"molecules":[140],"[Exons,":[141],"Introns,":[142],"CoDing":[143],"Sequence":[144],"(CDS)":[145],"UnTranslated":[147],"Regions":[148],"(UTRs)]":[149],"regarding":[152],"tissue/organ/cell":[153],"sources":[154],"where":[155],"has":[158,235],"observed.":[160],"It":[161],"also":[163],"possible":[164],"obtain":[166],"specific":[172],"gene":[173],"or":[174],"an":[175],"molecule":[177],"accession":[180],"numbers.":[181],"Search":[182],"results":[183],"provide":[184],"expressed":[190],"sequence":[191],"tags":[192],"(ESTs)":[193],"supporting":[194],"edited":[195],"bases,":[198],"existence":[205],"known":[207],"single":[208],"nucleotide":[209],"polymorphisms":[210],"(SNPs).":[211],"Editing":[212],"explored":[216],"UCSC":[218],"Ensembl":[220],"browsers,":[222],"conjunction":[224],"with":[225],"additional":[226],"provided":[228],"by":[229],"these":[230],"popular":[231],"browsers.":[233],"designed":[237],"researchers":[239],"seeking":[240],"developers":[248],"novel":[250],"algorithms":[251],"its":[253],"prediction.":[254],"AVAILABILITY:":[255],"accessible":[258],"at":[259],"http://darned.ucc.ie":[260]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":20},{"year":2022,"cited_by_count":20},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":23},{"year":2019,"cited_by_count":14},{"year":2018,"cited_by_count":21},{"year":2017,"cited_by_count":21},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":18},{"year":2013,"cited_by_count":18},{"year":2012,"cited_by_count":18}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}