{"id":"https://openalex.org/W2170836348","doi":"https://doi.org/10.1093/bioinformatics/btp707","title":"Penalized mixtures of factor analyzers with application to clustering high-dimensional microarray data","display_name":"Penalized mixtures of factor analyzers with application to clustering high-dimensional microarray data","publication_year":2009,"publication_date":"2009-12-23","ids":{"openalex":"https://openalex.org/W2170836348","doi":"https://doi.org/10.1093/bioinformatics/btp707","mag":"2170836348","pmid":"https://pubmed.ncbi.nlm.nih.gov/20031967"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btp707","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp707","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/4/501/48856080/bioinformatics_26_4_501.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/26/4/501/48856080/bioinformatics_26_4_501.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112388390","display_name":"Benhuai Xie","orcid":null},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Benhuai Xie","raw_affiliation_strings":["1 Division of Biostatistics, School of Public Health and 2 School of Statistics, University of Minnesota, Minneapolis, MN, USA"],"affiliations":[{"raw_affiliation_string":"1 Division of Biostatistics, School of Public Health and 2 School of Statistics, University of Minnesota, Minneapolis, MN, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018997928","display_name":"Wei Pan","orcid":"https://orcid.org/0000-0002-1159-0582"},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wei Pan","raw_affiliation_strings":["1 Division of Biostatistics, School of Public Health and 2 School of Statistics, University of Minnesota, Minneapolis, MN, USA"],"affiliations":[{"raw_affiliation_string":"1 Division of Biostatistics, School of Public Health and 2 School of Statistics, University of Minnesota, Minneapolis, MN, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074904348","display_name":"Xiaotong Shen","orcid":"https://orcid.org/0000-0003-1300-1451"},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaotong Shen","raw_affiliation_strings":["1 Division of Biostatistics, School of Public Health and 2 School of Statistics, University of Minnesota, Minneapolis, MN, USA"],"affiliations":[{"raw_affiliation_string":"1 Division of Biostatistics, School of Public Health and 2 School of Statistics, University of Minnesota, Minneapolis, MN, USA","institution_ids":["https://openalex.org/I130238516"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5112388390"],"corresponding_institution_ids":["https://openalex.org/I130238516"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":1.0784,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":{"value":0.77027395,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"26","issue":"4","first_page":"501","last_page":"508"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11901","display_name":"Bayesian Methods and Mixture Models","score":0.9915000200271606,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10057","display_name":"Face and Expression Recognition","score":0.9846000075340271,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.6852768063545227},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.602939784526825},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.5313361883163452},{"id":"https://openalex.org/keywords/factor","display_name":"Factor (programming language)","score":0.4261084198951721},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.33206266164779663},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.21196714043617249},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.19663164019584656},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.08145391941070557}],"concepts":[{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.6852768063545227},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.602939784526825},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.5313361883163452},{"id":"https://openalex.org/C2781039887","wikidata":"https://www.wikidata.org/wiki/Q1391724","display_name":"Factor (programming language)","level":2,"score":0.4261084198951721},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.33206266164779663},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.21196714043617249},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.19663164019584656},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.08145391941070557}],"mesh":[{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btp707","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp707","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/4/501/48856080/bioinformatics_26_4_501.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:20031967","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20031967","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.156.7640","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.156.7640","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.biostat.umn.edu/ftp/pub/2009/rr2009-019.pdf","raw_type":"text"},{"id":"pmh:oai:europepmc.org:2040785","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2852217","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btp707","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp707","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/4/501/48856080/bioinformatics_26_4_501.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3511853578","display_name":null,"funder_award_id":"HL65462","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G506360649","display_name":"Inference and Prediction in a Complex Discovery Process","funder_award_id":"0604394","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7289273017","display_name":"Nonseparable Multiclass Learning for Object Tracking","funder_award_id":"0328802","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2170836348.pdf","grobid_xml":"https://content.openalex.org/works/W2170836348.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W1662191912","https://openalex.org/W1972239934","https://openalex.org/W1988508705","https://openalex.org/W2000771269","https://openalex.org/W2011832962","https://openalex.org/W2017818759","https://openalex.org/W2023831651","https://openalex.org/W2033403400","https://openalex.org/W2047109555","https://openalex.org/W2049633694","https://openalex.org/W2052386156","https://openalex.org/W2081746825","https://openalex.org/W2108435369","https://openalex.org/W2109363337","https://openalex.org/W2111842831","https://openalex.org/W2134165090","https://openalex.org/W2134507164","https://openalex.org/W2138019504","https://openalex.org/W2140736261","https://openalex.org/W2144664383","https://openalex.org/W2150926065","https://openalex.org/W2152012752","https://openalex.org/W2154560360","https://openalex.org/W2156452366","https://openalex.org/W2169694221","https://openalex.org/W2171037347","https://openalex.org/W2800011543","https://openalex.org/W2914933231","https://openalex.org/W3105178084","https://openalex.org/W4235169531","https://openalex.org/W6637034065","https://openalex.org/W6656302719","https://openalex.org/W6676358527"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W2358668433","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W2382290278","https://openalex.org/W2478288626","https://openalex.org/W2350741829","https://openalex.org/W2530322880","https://openalex.org/W1596801655"],"abstract_inverted_index":{"To":[0],"model":[1],"non-independence":[2],"of":[3,17,31,60],"variables":[4],"(e.g.":[5],"correlated":[6],"gene":[7],"expressions)":[8],"while":[9],"alleviating":[10],"the":[11,14,29,56,61],"problem":[12],"with":[13,21,36],"large":[15],"number":[16],"unknown":[18],"parameters":[19],"associated":[20],"a":[22],"general":[23],"non-diagonal":[24],"covariance":[25],"matrix,":[26],"we":[27],"generalize":[28],"mixture":[30],"factor":[32],"analyzers":[33],"to":[34,54],"that":[35],"penalization,":[37],"which,":[38],"among":[39],"others,":[40],"can":[41],"effectively":[42],"realize":[43],"variable":[44],"selection.":[45],"We":[46],"use":[47],"simulated":[48],"data":[49,53],"and":[50,58],"real":[51],"microarray":[52],"illustrate":[55],"utility":[57],"advantages":[59],"proposed":[62],"method":[63],"over":[64],"several":[65],"existing":[66],"ones.":[67]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":4}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}