{"id":"https://openalex.org/W2111627808","doi":"https://doi.org/10.1093/bioinformatics/btp502","title":"Statistical methods for gene set co-expression analysis","display_name":"Statistical methods for gene set co-expression analysis","publication_year":2009,"publication_date":"2009-08-18","ids":{"openalex":"https://openalex.org/W2111627808","doi":"https://doi.org/10.1093/bioinformatics/btp502","mag":"2111627808","pmid":"https://pubmed.ncbi.nlm.nih.gov/19689953"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btp502","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp502","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/21/2780/48998357/bioinformatics_25_21_2780.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/25/21/2780/48998357/bioinformatics_25_21_2780.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112356210","display_name":"YounJeong Choi","orcid":null},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"YounJeong Choi","raw_affiliation_strings":["1 Department of Statistics and2 Department of Biostatistics and Medical Informatics, University of Wisconsin - Madison 1300 University Avenue, Madison, WI 53706, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Statistics and2 Department of Biostatistics and Medical Informatics, University of Wisconsin - Madison 1300 University Avenue, Madison, WI 53706, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086207166","display_name":"Christina Kendziorski","orcid":"https://orcid.org/0000-0002-0700-6267"},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christina Kendziorski","raw_affiliation_strings":["1 Department of Statistics and2 Department of Biostatistics and Medical Informatics, University of Wisconsin - Madison 1300 University Avenue, Madison, WI 53706, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Statistics and2 Department of Biostatistics and Medical Informatics, University of Wisconsin - Madison 1300 University Avenue, Madison, WI 53706, USA","institution_ids":["https://openalex.org/I135310074"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5112356210"],"corresponding_institution_ids":["https://openalex.org/I135310074"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":3.6394,"has_fulltext":true,"cited_by_count":165,"citation_normalized_percentile":{"value":0.93678559,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"25","issue":"21","first_page":"2780","last_page":"2786"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.992900013923645,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9702000021934509,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/false-discovery-rate","display_name":"False discovery rate","score":0.7002740502357483},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5937615633010864},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.5272504091262817},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5075598955154419},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5033909678459167},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4699946343898773},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.46629446744918823},{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.4462423026561737},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3503091633319855},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.2949010133743286}],"concepts":[{"id":"https://openalex.org/C193244246","wikidata":"https://www.wikidata.org/wiki/Q5432696","display_name":"False discovery rate","level":3,"score":0.7002740502357483},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5937615633010864},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.5272504091262817},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5075598955154419},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5033909678459167},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4699946343898773},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.46629446744918823},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.4462423026561737},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3503091633319855},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2949010133743286},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btp502","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp502","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/21/2780/48998357/bioinformatics_25_21_2780.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:19689953","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19689953","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.540.7575","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.540.7575","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://bioinformatics.oxfordjournals.org/content/early/2009/08/18/bioinformatics.btp502.full.pdf","raw_type":"text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2781749","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2781749","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btp502","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp502","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/21/2780/48998357/bioinformatics_25_21_2780.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7300000190734863,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2111627808.pdf","grobid_xml":"https://content.openalex.org/works/W2111627808.grobid-xml"},"referenced_works_count":74,"referenced_works":["https://openalex.org/W59013595","https://openalex.org/W139767586","https://openalex.org/W1562557719","https://openalex.org/W1583052686","https://openalex.org/W1943552404","https://openalex.org/W1964895626","https://openalex.org/W1968005447","https://openalex.org/W1968055555","https://openalex.org/W1988078905","https://openalex.org/W1988977806","https://openalex.org/W1990538835","https://openalex.org/W1995017987","https://openalex.org/W1995018466","https://openalex.org/W1995449426","https://openalex.org/W2000771269","https://openalex.org/W2003737968","https://openalex.org/W2004151301","https://openalex.org/W2007621574","https://openalex.org/W2009529714","https://openalex.org/W2021129827","https://openalex.org/W2026182888","https://openalex.org/W2036351528","https://openalex.org/W2051551471","https://openalex.org/W2051636780","https://openalex.org/W2059467226","https://openalex.org/W2059551478","https://openalex.org/W2061716303","https://openalex.org/W2062014401","https://openalex.org/W2064119981","https://openalex.org/W2065901160","https://openalex.org/W2071514232","https://openalex.org/W2092627144","https://openalex.org/W2097413644","https://openalex.org/W2103017472","https://openalex.org/W2109907677","https://openalex.org/W2111513463","https://openalex.org/W2114954827","https://openalex.org/W2117994680","https://openalex.org/W2120147434","https://openalex.org/W2121195642","https://openalex.org/W2121905508","https://openalex.org/W2124557052","https://openalex.org/W2130410032","https://openalex.org/W2138255346","https://openalex.org/W2138426950","https://openalex.org/W2139036189","https://openalex.org/W2139807849","https://openalex.org/W2143489962","https://openalex.org/W2146455987","https://openalex.org/W2148825532","https://openalex.org/W2150882058","https://openalex.org/W2151820055","https://openalex.org/W2152155643","https://openalex.org/W2153201655","https://openalex.org/W2156138784","https://openalex.org/W2157268049","https://openalex.org/W2158940923","https://openalex.org/W2159482845","https://openalex.org/W2159887702","https://openalex.org/W2160105055","https://openalex.org/W2160697532","https://openalex.org/W2162974906","https://openalex.org/W2165133998","https://openalex.org/W2165816035","https://openalex.org/W2168176104","https://openalex.org/W2169056321","https://openalex.org/W2203974440","https://openalex.org/W2495373072","https://openalex.org/W3101608900","https://openalex.org/W4247435783","https://openalex.org/W4294216483","https://openalex.org/W6677920359","https://openalex.org/W6680610188","https://openalex.org/W6683356575"],"related_works":["https://openalex.org/W2389124870","https://openalex.org/W2364737130","https://openalex.org/W2377438999","https://openalex.org/W2394308601","https://openalex.org/W2114540137","https://openalex.org/W2053053668","https://openalex.org/W2388669904","https://openalex.org/W1995366224","https://openalex.org/W3133147219","https://openalex.org/W2415025170"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":20},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":15},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":10}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}