{"id":"https://openalex.org/W2142753962","doi":"https://doi.org/10.1093/bioinformatics/btp468","title":"<i>metahdep</i>: meta-analysis of hierarchically dependent gene expression studies","display_name":"<i>metahdep</i>: meta-analysis of hierarchically dependent gene expression studies","publication_year":2009,"publication_date":"2009-07-30","ids":{"openalex":"https://openalex.org/W2142753962","doi":"https://doi.org/10.1093/bioinformatics/btp468","mag":"2142753962","pmid":"https://pubmed.ncbi.nlm.nih.gov/19648140"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btp468","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp468","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/19/2619/48993718/bioinformatics_25_19_2619.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/25/19/2619/48993718/bioinformatics_25_19_2619.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058847502","display_name":"John R. Stevens","orcid":"https://orcid.org/0000-0002-2908-7918"},"institutions":[{"id":"https://openalex.org/I121980950","display_name":"Utah State University","ror":"https://ror.org/00h6set76","country_code":"US","type":"education","lineage":["https://openalex.org/I121980950"]},{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"John R. Stevens","raw_affiliation_strings":["1 Department of Mathematics and Statistics, Utah State University, Logan, UT 84322-3900 and 2Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792-4675, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Mathematics and Statistics, Utah State University, Logan, UT 84322-3900 and 2Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792-4675, USA","institution_ids":["https://openalex.org/I121980950","https://openalex.org/I135310074"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003902802","display_name":"Gabriel Nicholas","orcid":"https://orcid.org/0009-0004-2946-7736"},"institutions":[{"id":"https://openalex.org/I121980950","display_name":"Utah State University","ror":"https://ror.org/00h6set76","country_code":"US","type":"education","lineage":["https://openalex.org/I121980950"]},{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gabriel Nicholas","raw_affiliation_strings":["1 Department of Mathematics and Statistics, Utah State University, Logan, UT 84322-3900 and 2Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792-4675, USA"],"affiliations":[{"raw_affiliation_string":"1 Department of Mathematics and Statistics, Utah State University, Logan, UT 84322-3900 and 2Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792-4675, USA","institution_ids":["https://openalex.org/I121980950","https://openalex.org/I135310074"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5058847502"],"corresponding_institution_ids":["https://openalex.org/I121980950","https://openalex.org/I135310074"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.5249,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.66441924,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"25","issue":"19","first_page":"2619","last_page":"2620"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bioconductor","display_name":"Bioconductor","score":0.9570962190628052},{"id":"https://openalex.org/keywords/covariate","display_name":"Covariate","score":0.8075938820838928},{"id":"https://openalex.org/keywords/r-package","display_name":"R package","score":0.6872789859771729},{"id":"https://openalex.org/keywords/meta-analysis","display_name":"Meta-analysis","score":0.568415105342865},{"id":"https://openalex.org/keywords/software-package","display_name":"Software package","score":0.5559414625167847},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.5352606773376465},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.524921715259552},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.5234529376029968},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5012087821960449},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.48686614632606506},{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.4777109622955322},{"id":"https://openalex.org/keywords/sampling","display_name":"Sampling (signal processing)","score":0.4496673345565796},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"Gene expression profiling","score":0.4365122616291046},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.42423123121261597},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.38789817690849304},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.37424135208129883},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3328459858894348},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.24742427468299866},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.15109896659851074},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.15003198385238647},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.12060174345970154},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.08900246024131775}],"concepts":[{"id":"https://openalex.org/C2779694297","wikidata":"https://www.wikidata.org/wiki/Q2888953","display_name":"Bioconductor","level":3,"score":0.9570962190628052},{"id":"https://openalex.org/C119043178","wikidata":"https://www.wikidata.org/wiki/Q320723","display_name":"Covariate","level":2,"score":0.8075938820838928},{"id":"https://openalex.org/C2984074130","wikidata":"https://www.wikidata.org/wiki/Q73539779","display_name":"R package","level":2,"score":0.6872789859771729},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.568415105342865},{"id":"https://openalex.org/C3020440742","wikidata":"https://www.wikidata.org/wiki/Q1176855","display_name":"Software package","level":3,"score":0.5559414625167847},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.5352606773376465},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.524921715259552},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.5234529376029968},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5012087821960449},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.48686614632606506},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.4777109622955322},{"id":"https://openalex.org/C140779682","wikidata":"https://www.wikidata.org/wiki/Q210868","display_name":"Sampling (signal processing)","level":3,"score":0.4496673345565796},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.4365122616291046},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.42423123121261597},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.38789817690849304},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.37424135208129883},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3328459858894348},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.24742427468299866},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15109896659851074},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.15003198385238647},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.12060174345970154},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08900246024131775},{"id":"https://openalex.org/C106131492","wikidata":"https://www.wikidata.org/wiki/Q3072260","display_name":"Filter (signal processing)","level":2,"score":0.0},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015201","descriptor_name":"Meta-Analysis as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015201","descriptor_name":"Meta-Analysis as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015201","descriptor_name":"Meta-Analysis as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btp468","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp468","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/19/2619/48993718/bioinformatics_25_19_2619.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:19648140","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19648140","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btp468","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp468","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/19/2619/48993718/bioinformatics_25_19_2619.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309198","display_name":"Utah State University","ror":"https://ror.org/00h6set76"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2142753962.pdf","grobid_xml":"https://content.openalex.org/works/W2142753962.grobid-xml"},"referenced_works_count":89,"referenced_works":["https://openalex.org/W14315273","https://openalex.org/W999855952","https://openalex.org/W1522329101","https://openalex.org/W1542264887","https://openalex.org/W1543409524","https://openalex.org/W1583148430","https://openalex.org/W1611514155","https://openalex.org/W1638590376","https://openalex.org/W1954133730","https://openalex.org/W1964895626","https://openalex.org/W1970886815","https://openalex.org/W1980941036","https://openalex.org/W1982804078","https://openalex.org/W1985195836","https://openalex.org/W1986103239","https://openalex.org/W1988738875","https://openalex.org/W1999649023","https://openalex.org/W2002097809","https://openalex.org/W2004241753","https://openalex.org/W2006289803","https://openalex.org/W2007331929","https://openalex.org/W2008326798","https://openalex.org/W2012171191","https://openalex.org/W2012324563","https://openalex.org/W2013248652","https://openalex.org/W2016560527","https://openalex.org/W2017290177","https://openalex.org/W2019568999","https://openalex.org/W2019926860","https://openalex.org/W2030936432","https://openalex.org/W2032991645","https://openalex.org/W2034233269","https://openalex.org/W2038437697","https://openalex.org/W2039709829","https://openalex.org/W2043282204","https://openalex.org/W2046817896","https://openalex.org/W2050727544","https://openalex.org/W2051947267","https://openalex.org/W2053261488","https://openalex.org/W2053371544","https://openalex.org/W2055121395","https://openalex.org/W2055657535","https://openalex.org/W2060010690","https://openalex.org/W2065086568","https://openalex.org/W2067633002","https://openalex.org/W2068716420","https://openalex.org/W2073870011","https://openalex.org/W2074988843","https://openalex.org/W2075251022","https://openalex.org/W2080076458","https://openalex.org/W2084458080","https://openalex.org/W2084761937","https://openalex.org/W2085841611","https://openalex.org/W2097191932","https://openalex.org/W2101363646","https://openalex.org/W2104315295","https://openalex.org/W2104696504","https://openalex.org/W2109909789","https://openalex.org/W2109971798","https://openalex.org/W2113799034","https://openalex.org/W2114849059","https://openalex.org/W2118202495","https://openalex.org/W2120478433","https://openalex.org/W2121498145","https://openalex.org/W2121842388","https://openalex.org/W2127573941","https://openalex.org/W2127818820","https://openalex.org/W2132499228","https://openalex.org/W2134842047","https://openalex.org/W2135577920","https://openalex.org/W2137536478","https://openalex.org/W2141524836","https://openalex.org/W2143146123","https://openalex.org/W2147339766","https://openalex.org/W2153784703","https://openalex.org/W2154568954","https://openalex.org/W2154981570","https://openalex.org/W2161821961","https://openalex.org/W2167240576","https://openalex.org/W2170989872","https://openalex.org/W2184205536","https://openalex.org/W2189513341","https://openalex.org/W2320567889","https://openalex.org/W2322277401","https://openalex.org/W2343077482","https://openalex.org/W2410452109","https://openalex.org/W2797884775","https://openalex.org/W4233245650","https://openalex.org/W6641535312"],"related_works":["https://openalex.org/W2142753962","https://openalex.org/W2112504441","https://openalex.org/W2131192238","https://openalex.org/W2122223946","https://openalex.org/W3032874291","https://openalex.org/W2053053668","https://openalex.org/W2773571775","https://openalex.org/W1971076179","https://openalex.org/W4376288166","https://openalex.org/W2024602320"],"abstract_inverted_index":{"http://bioconductor.org/packages/release/Software.html":[0]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2016-06-24T00:00:00"}