{"id":"https://openalex.org/W2130983094","doi":"https://doi.org/10.1093/bioinformatics/btp409","title":"FRED\u2014a framework for T-cell epitope detection","display_name":"FRED\u2014a framework for T-cell epitope detection","publication_year":2009,"publication_date":"2009-07-05","ids":{"openalex":"https://openalex.org/W2130983094","doi":"https://doi.org/10.1093/bioinformatics/btp409","mag":"2130983094","pmid":"https://pubmed.ncbi.nlm.nih.gov/19578173"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btp409","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp409","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/20/2758/48995417/bioinformatics_25_20_2758.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/25/20/2758/48995417/bioinformatics_25_20_2758.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010059672","display_name":"Magdalena Feldhahn","orcid":null},"institutions":[{"id":"https://openalex.org/I4210143795","display_name":"AstraZeneca (Sweden)","ror":"https://ror.org/04wwrrg31","country_code":"SE","type":"company","lineage":["https://openalex.org/I105036370","https://openalex.org/I4210143795"]},{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE","SE"],"is_corresponding":true,"raw_author_name":"Magdalena Feldhahn","raw_affiliation_strings":["1 Division for Simulation of Biological Systems, WSI/ZBIT, University of T\u00fcbingen, Sand 14, D-72076 T\u00fcbingen, Germany and 2 Present address: Molecular Toxicology, Safety Assessment, AstraZeneca R&D, S-15185 S\u00f6dert\u00e4lje, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Division for Simulation of Biological Systems, WSI/ZBIT, University of T\u00fcbingen, Sand 14, D-72076 T\u00fcbingen, Germany and 2 Present address: Molecular Toxicology, Safety Assessment, AstraZeneca R&D, S-15185 S\u00f6dert\u00e4lje, Sweden","institution_ids":["https://openalex.org/I4210143795","https://openalex.org/I8087733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028148209","display_name":"Pierre D\u00f6nnes","orcid":"https://orcid.org/0000-0002-4613-2952"},"institutions":[{"id":"https://openalex.org/I4210143795","display_name":"AstraZeneca (Sweden)","ror":"https://ror.org/04wwrrg31","country_code":"SE","type":"company","lineage":["https://openalex.org/I105036370","https://openalex.org/I4210143795"]},{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE","SE"],"is_corresponding":false,"raw_author_name":"Pierre D\u00f6nnes","raw_affiliation_strings":["1 Division for Simulation of Biological Systems, WSI/ZBIT, University of T\u00fcbingen, Sand 14, D-72076 T\u00fcbingen, Germany and 2 Present address: Molecular Toxicology, Safety Assessment, AstraZeneca R&D, S-15185 S\u00f6dert\u00e4lje, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Division for Simulation of Biological Systems, WSI/ZBIT, University of T\u00fcbingen, Sand 14, D-72076 T\u00fcbingen, Germany and 2 Present address: Molecular Toxicology, Safety Assessment, AstraZeneca R&D, S-15185 S\u00f6dert\u00e4lje, Sweden","institution_ids":["https://openalex.org/I4210143795","https://openalex.org/I8087733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082172915","display_name":"Philipp Thiel","orcid":"https://orcid.org/0000-0001-9498-1214"},"institutions":[{"id":"https://openalex.org/I4210143795","display_name":"AstraZeneca (Sweden)","ror":"https://ror.org/04wwrrg31","country_code":"SE","type":"company","lineage":["https://openalex.org/I105036370","https://openalex.org/I4210143795"]},{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE","SE"],"is_corresponding":false,"raw_author_name":"Philipp Thiel","raw_affiliation_strings":["1 Division for Simulation of Biological Systems, WSI/ZBIT, University of T\u00fcbingen, Sand 14, D-72076 T\u00fcbingen, Germany and 2 Present address: Molecular Toxicology, Safety Assessment, AstraZeneca R&D, S-15185 S\u00f6dert\u00e4lje, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Division for Simulation of Biological Systems, WSI/ZBIT, University of T\u00fcbingen, Sand 14, D-72076 T\u00fcbingen, Germany and 2 Present address: Molecular Toxicology, Safety Assessment, AstraZeneca R&D, S-15185 S\u00f6dert\u00e4lje, Sweden","institution_ids":["https://openalex.org/I4210143795","https://openalex.org/I8087733"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053621010","display_name":"Oliver Kohlbacher","orcid":"https://orcid.org/0000-0003-1739-4598"},"institutions":[{"id":"https://openalex.org/I4210143795","display_name":"AstraZeneca (Sweden)","ror":"https://ror.org/04wwrrg31","country_code":"SE","type":"company","lineage":["https://openalex.org/I105036370","https://openalex.org/I4210143795"]},{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE","SE"],"is_corresponding":false,"raw_author_name":"Oliver Kohlbacher","raw_affiliation_strings":["1 Division for Simulation of Biological Systems, WSI/ZBIT, University of T\u00fcbingen, Sand 14, D-72076 T\u00fcbingen, Germany and 2 Present address: Molecular Toxicology, Safety Assessment, AstraZeneca R&D, S-15185 S\u00f6dert\u00e4lje, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Division for Simulation of Biological Systems, WSI/ZBIT, University of T\u00fcbingen, Sand 14, D-72076 T\u00fcbingen, Germany and 2 Present address: Molecular Toxicology, Safety Assessment, AstraZeneca R&D, S-15185 S\u00f6dert\u00e4lje, Sweden","institution_ids":["https://openalex.org/I4210143795","https://openalex.org/I8087733"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5010059672"],"corresponding_institution_ids":["https://openalex.org/I4210143795","https://openalex.org/I8087733"],"apc_list":{"value":3989,"currency":"USD","value_usd":3989},"apc_paid":{"value":3989,"currency":"USD","value_usd":3989},"fwci":0.77,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.71087388,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"25","issue":"20","first_page":"2758","last_page":"2759"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/python","display_name":"Python (programming language)","score":0.7999213933944702},{"id":"https://openalex.org/keywords/epitope","display_name":"Epitope","score":0.7739179134368896},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6953628659248352},{"id":"https://openalex.org/keywords/modular-design","display_name":"Modular design","score":0.631422758102417},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.5340880751609802},{"id":"https://openalex.org/keywords/major-histocompatibility-complex","display_name":"Major histocompatibility complex","score":0.5095184445381165},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.46635475754737854},{"id":"https://openalex.org/keywords/download","display_name":"Download","score":0.45744699239730835},{"id":"https://openalex.org/keywords/software-engineering","display_name":"Software engineering","score":0.4563066065311432},{"id":"https://openalex.org/keywords/key","display_name":"Key (lock)","score":0.41540732979774475},{"id":"https://openalex.org/keywords/antigen","display_name":"Antigen","score":0.3960312306880951},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.35184547305107117},{"id":"https://openalex.org/keywords/operating-system","display_name":"Operating system","score":0.2675524055957794},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.18459159135818481},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.12748238444328308}],"concepts":[{"id":"https://openalex.org/C519991488","wikidata":"https://www.wikidata.org/wiki/Q28865","display_name":"Python (programming language)","level":2,"score":0.7999213933944702},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.7739179134368896},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6953628659248352},{"id":"https://openalex.org/C101468663","wikidata":"https://www.wikidata.org/wiki/Q1620158","display_name":"Modular design","level":2,"score":0.631422758102417},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.5340880751609802},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.5095184445381165},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.46635475754737854},{"id":"https://openalex.org/C2780154274","wikidata":"https://www.wikidata.org/wiki/Q7126717","display_name":"Download","level":2,"score":0.45744699239730835},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.4563066065311432},{"id":"https://openalex.org/C26517878","wikidata":"https://www.wikidata.org/wiki/Q228039","display_name":"Key (lock)","level":2,"score":0.41540732979774475},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.3960312306880951},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.35184547305107117},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.2675524055957794},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18459159135818481},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.12748238444328308}],"mesh":[{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018984","descriptor_name":"Epitopes, T-Lymphocyte","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018984","descriptor_name":"Epitopes, T-Lymphocyte","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018984","descriptor_name":"Epitopes, T-Lymphocyte","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btp409","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp409","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/20/2758/48995417/bioinformatics_25_20_2758.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:19578173","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19578173","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2759545","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2759545","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.532.476","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.532.476","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://bioinformatics.oxfordjournals.org/content/early/2009/07/06/bioinformatics.btp409.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btp409","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp409","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/20/2758/48995417/bioinformatics_25_20_2758.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Industry, innovation and infrastructure","id":"https://metadata.un.org/sdg/9","score":0.6000000238418579}],"awards":[{"id":"https://openalex.org/G1560004781","display_name":null,"funder_award_id":"SFB 685","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G2530704891","display_name":null,"funder_award_id":"SFB685/B1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2130983094.pdf","grobid_xml":"https://content.openalex.org/works/W2130983094.grobid-xml"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W1994048581","https://openalex.org/W2020564539","https://openalex.org/W2040270003","https://openalex.org/W2062018073","https://openalex.org/W2107665842","https://openalex.org/W2111866752","https://openalex.org/W2118045183","https://openalex.org/W2125644345","https://openalex.org/W2133478416","https://openalex.org/W2137116717","https://openalex.org/W2142739377","https://openalex.org/W2149350146","https://openalex.org/W2161871188","https://openalex.org/W2166831581"],"related_works":["https://openalex.org/W1979044599","https://openalex.org/W2183842793","https://openalex.org/W2021824670","https://openalex.org/W2009867644","https://openalex.org/W2363997565","https://openalex.org/W1981120125","https://openalex.org/W3036615648","https://openalex.org/W2408448169","https://openalex.org/W2182598264","https://openalex.org/W2075879923"],"abstract_inverted_index":{"UNLABELLED:":[0],"Over":[1],"the":[2,14,25,34,82,101],"last":[3],"decade,":[4],"immunoinformatics":[5],"has":[6],"made":[7],"significant":[8],"progress.":[9],"Computational":[10],"approaches,":[11],"in":[12,57,93,95],"particular":[13],"prediction":[15,68],"of":[16,27,38,84,103],"T-cell":[17],"epitopes":[18],"using":[19],"machine":[20],"learning":[21],"methods,":[22],"are":[23],"at":[24,113],"core":[26],"modern":[28],"vaccine":[29],"design.":[30],"Large-scale":[31],"analyses":[32],"and":[33,73,88,99],"integration":[35,102],"or":[36],"comparison":[37],"different":[39],"methods":[40,69],"become":[41],"increasingly":[42],"important.":[43],"We":[44],"have":[45],"developed":[46],"FRED,":[47],"an":[48],"extendable,":[49],"open":[50],"source":[51],"software":[52],"framework":[53],"for":[54,70,81,111],"key":[55],"tasks":[56],"immunoinformatics.":[58],"In":[59],"this,":[60],"its":[61],"first":[62],"version,":[63],"FRED":[64,90,107],"offers":[65],"easily":[66],"accessible":[67],"MHC":[71],"binding":[72],"antigen":[74,85],"processing":[75],"as":[76,78],"well":[77],"general":[79],"infrastructure":[80],"handling":[83],"sequence":[86],"data":[87],"epitopes.":[89],"is":[91,108],"implemented":[92],"Python":[94],"a":[96],"modular":[97],"way":[98],"allows":[100],"external":[104],"methods.":[105],"AVAILABILITY:":[106],"freely":[109],"available":[110],"download":[112],"http://www-bs.informatik.uni-tuebingen.de/Software/FRED.":[114]},"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-08-26T07:47:46.906454","created_date":"2025-10-10T00:00:00"}