{"id":"https://openalex.org/W2141931711","doi":"https://doi.org/10.1093/bioinformatics/btp172","title":"<i>In silico</i>analysis of promoter regions from cold-induced genes in rice (<i>Oryza sativa</i>L.) and<i>Arabidopsis thaliana</i>reveals the importance of combinatorial control","display_name":"<i>In silico</i>analysis of promoter regions from cold-induced genes in rice (<i>Oryza sativa</i>L.) and<i>Arabidopsis thaliana</i>reveals the importance of combinatorial control","publication_year":2009,"publication_date":"2009-03-25","ids":{"openalex":"https://openalex.org/W2141931711","doi":"https://doi.org/10.1093/bioinformatics/btp172","mag":"2141931711","pmid":"https://pubmed.ncbi.nlm.nih.gov/19321735"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btp172","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp172","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/11/1345/48988629/bioinformatics_25_11_1345.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/25/11/1345/48988629/bioinformatics_25_11_1345.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014919188","display_name":"Angelica Lindl\u00f6f","orcid":"https://orcid.org/0000-0003-1837-429X"},"institutions":[{"id":"https://openalex.org/I205158640","display_name":"University of Sk\u00f6vde","ror":"https://ror.org/051mrsz47","country_code":"SE","type":"education","lineage":["https://openalex.org/I205158640"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Angelica Lindl\u00f6f","raw_affiliation_strings":["1 Systems Biology Research Centre, School of Life Sciences, University of Sk\u00f6vde, Box 408, 541 28 Sk\u00f6vde, 2Department of Cell and Molecular biology, Medicinaregatan 9C, Box 462 and 3Department of Plant and Environmental Sciences, Box 461, Gothenburg University, SE405 30 G\u00f6teborg, Sweden"],"affiliations":[{"raw_affiliation_string":"1 Systems Biology Research Centre, School of Life Sciences, University of Sk\u00f6vde, Box 408, 541 28 Sk\u00f6vde, 2Department of Cell and Molecular biology, Medicinaregatan 9C, Box 462 and 3Department of Plant and Environmental Sciences, Box 461, Gothenburg University, SE405 30 G\u00f6teborg, Sweden","institution_ids":["https://openalex.org/I205158640"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015572840","display_name":"Marcus Br\u00e4utigam","orcid":null},"institutions":[{"id":"https://openalex.org/I205158640","display_name":"University of Sk\u00f6vde","ror":"https://ror.org/051mrsz47","country_code":"SE","type":"education","lineage":["https://openalex.org/I205158640"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Marcus Br\u00e4utigam","raw_affiliation_strings":["1 Systems Biology Research Centre, School of Life Sciences, University of Sk\u00f6vde, Box 408, 541 28 Sk\u00f6vde, 2Department of Cell and Molecular biology, Medicinaregatan 9C, Box 462 and 3Department of Plant and Environmental Sciences, Box 461, Gothenburg University, SE405 30 G\u00f6teborg, Sweden"],"affiliations":[{"raw_affiliation_string":"1 Systems Biology Research Centre, School of Life Sciences, University of Sk\u00f6vde, Box 408, 541 28 Sk\u00f6vde, 2Department of Cell and Molecular biology, Medicinaregatan 9C, Box 462 and 3Department of Plant and Environmental Sciences, Box 461, Gothenburg University, SE405 30 G\u00f6teborg, Sweden","institution_ids":["https://openalex.org/I205158640"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010679735","display_name":"Aakash Chawade","orcid":"https://orcid.org/0000-0002-6500-4139"},"institutions":[{"id":"https://openalex.org/I205158640","display_name":"University of Sk\u00f6vde","ror":"https://ror.org/051mrsz47","country_code":"SE","type":"education","lineage":["https://openalex.org/I205158640"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Aakash Chawade","raw_affiliation_strings":["1 Systems Biology Research Centre, School of Life Sciences, University of Sk\u00f6vde, Box 408, 541 28 Sk\u00f6vde, 2Department of Cell and Molecular biology, Medicinaregatan 9C, Box 462 and 3Department of Plant and Environmental Sciences, Box 461, Gothenburg University, SE405 30 G\u00f6teborg, Sweden"],"affiliations":[{"raw_affiliation_string":"1 Systems Biology Research Centre, School of Life Sciences, University of Sk\u00f6vde, Box 408, 541 28 Sk\u00f6vde, 2Department of Cell and Molecular biology, Medicinaregatan 9C, Box 462 and 3Department of Plant and Environmental Sciences, Box 461, Gothenburg University, SE405 30 G\u00f6teborg, Sweden","institution_ids":["https://openalex.org/I205158640"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034625560","display_name":"Olof Olsson","orcid":"https://orcid.org/0000-0003-3962-9183"},"institutions":[{"id":"https://openalex.org/I205158640","display_name":"University of Sk\u00f6vde","ror":"https://ror.org/051mrsz47","country_code":"SE","type":"education","lineage":["https://openalex.org/I205158640"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Olof Olsson","raw_affiliation_strings":["1 Systems Biology Research Centre, School of Life Sciences, University of Sk\u00f6vde, Box 408, 541 28 Sk\u00f6vde, 2Department of Cell and Molecular biology, Medicinaregatan 9C, Box 462 and 3Department of Plant and Environmental Sciences, Box 461, Gothenburg University, SE405 30 G\u00f6teborg, Sweden"],"affiliations":[{"raw_affiliation_string":"1 Systems Biology Research Centre, School of Life Sciences, University of Sk\u00f6vde, Box 408, 541 28 Sk\u00f6vde, 2Department of Cell and Molecular biology, Medicinaregatan 9C, Box 462 and 3Department of Plant and Environmental Sciences, Box 461, Gothenburg University, SE405 30 G\u00f6teborg, Sweden","institution_ids":["https://openalex.org/I205158640"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056458463","display_name":"Bj\u00f6rn Olsson","orcid":"https://orcid.org/0000-0001-6254-4335"},"institutions":[{"id":"https://openalex.org/I205158640","display_name":"University of Sk\u00f6vde","ror":"https://ror.org/051mrsz47","country_code":"SE","type":"education","lineage":["https://openalex.org/I205158640"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Bj\u00f6rn Olsson","raw_affiliation_strings":["1 Systems Biology Research Centre, School of Life Sciences, University of Sk\u00f6vde, Box 408, 541 28 Sk\u00f6vde, 2Department of Cell and Molecular biology, Medicinaregatan 9C, Box 462 and 3Department of Plant and Environmental Sciences, Box 461, Gothenburg University, SE405 30 G\u00f6teborg, Sweden"],"affiliations":[{"raw_affiliation_string":"1 Systems Biology Research Centre, School of Life Sciences, University of Sk\u00f6vde, Box 408, 541 28 Sk\u00f6vde, 2Department of Cell and Molecular biology, Medicinaregatan 9C, Box 462 and 3Department of Plant and Environmental Sciences, Box 461, Gothenburg University, SE405 30 G\u00f6teborg, Sweden","institution_ids":["https://openalex.org/I205158640"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5014919188"],"corresponding_institution_ids":["https://openalex.org/I205158640"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":0.6709,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.70012198,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"25","issue":"11","first_page":"1345","last_page":"1348"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11237","display_name":"Plant Gene Expression Analysis","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11237","display_name":"Plant Gene Expression Analysis","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10014","display_name":"Plant Stress Responses and Tolerance","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oryza-sativa","display_name":"Oryza sativa","score":0.8015503883361816},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.7106984853744507},{"id":"https://openalex.org/keywords/in-silico","display_name":"In silico","score":0.7052392959594727},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6314600110054016},{"id":"https://openalex.org/keywords/arabidopsis","display_name":"Arabidopsis","score":0.5721291899681091},{"id":"https://openalex.org/keywords/transcription-factor","display_name":"Transcription factor","score":0.5563732385635376},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5342596769332886},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5311155319213867},{"id":"https://openalex.org/keywords/oryza","display_name":"Oryza","score":0.5001437664031982},{"id":"https://openalex.org/keywords/organism","display_name":"Organism","score":0.41742709279060364},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.30802881717681885},{"id":"https://openalex.org/keywords/mutant","display_name":"Mutant","score":0.05369052290916443}],"concepts":[{"id":"https://openalex.org/C2778543611","wikidata":"https://www.wikidata.org/wiki/Q161426","display_name":"Oryza sativa","level":3,"score":0.8015503883361816},{"id":"https://openalex.org/C2775988993","wikidata":"https://www.wikidata.org/wiki/Q158695","display_name":"Arabidopsis thaliana","level":4,"score":0.7106984853744507},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.7052392959594727},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6314600110054016},{"id":"https://openalex.org/C2779491563","wikidata":"https://www.wikidata.org/wiki/Q157892","display_name":"Arabidopsis","level":4,"score":0.5721291899681091},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5563732385635376},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5342596769332886},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5311155319213867},{"id":"https://openalex.org/C2777923347","wikidata":"https://www.wikidata.org/wiki/Q690633","display_name":"Oryza","level":4,"score":0.5001437664031982},{"id":"https://openalex.org/C137858568","wikidata":"https://www.wikidata.org/wiki/Q7239","display_name":"Organism","level":2,"score":0.41742709279060364},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.30802881717681885},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.05369052290916443}],"mesh":[{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003080","descriptor_name":"Cold Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003080","descriptor_name":"Cold Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003080","descriptor_name":"Cold Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012275","descriptor_name":"Oryza","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012275","descriptor_name":"Oryza","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012275","descriptor_name":"Oryza","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017343","descriptor_name":"Genes, Plant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017343","descriptor_name":"Genes, Plant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017343","descriptor_name":"Genes, Plant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018506","descriptor_name":"Gene Expression Regulation, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018506","descriptor_name":"Gene Expression Regulation, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018506","descriptor_name":"Gene Expression Regulation, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018745","descriptor_name":"Genome, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018745","descriptor_name":"Genome, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018745","descriptor_name":"Genome, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btp172","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp172","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/11/1345/48988629/bioinformatics_25_11_1345.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:19321735","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19321735","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:2682518","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2682518","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btp172","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp172","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/11/1345/48988629/bioinformatics_25_11_1345.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.5,"id":"https://metadata.un.org/sdg/2"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2141931711.pdf","grobid_xml":"https://content.openalex.org/works/W2141931711.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W191237385","https://openalex.org/W1979119703","https://openalex.org/W1999351612","https://openalex.org/W2008491350","https://openalex.org/W2021144420","https://openalex.org/W2035908878","https://openalex.org/W2067660931","https://openalex.org/W2073727170","https://openalex.org/W2083722533","https://openalex.org/W2095617232","https://openalex.org/W2096860868","https://openalex.org/W2098222328","https://openalex.org/W2100651362","https://openalex.org/W2101814492","https://openalex.org/W2103107012","https://openalex.org/W2106541825","https://openalex.org/W2107593640","https://openalex.org/W2107714731","https://openalex.org/W2110065044","https://openalex.org/W2125508747","https://openalex.org/W2127306071","https://openalex.org/W2129308725","https://openalex.org/W2132126361","https://openalex.org/W2142269897","https://openalex.org/W2143198129","https://openalex.org/W2146018911","https://openalex.org/W2158860643","https://openalex.org/W2169115409","https://openalex.org/W6678921327","https://openalex.org/W6680985102"],"related_works":["https://openalex.org/W2366048438","https://openalex.org/W1998405066","https://openalex.org/W3143277863","https://openalex.org/W2064423757","https://openalex.org/W2898710483","https://openalex.org/W2030501883","https://openalex.org/W2105329935","https://openalex.org/W2947569759","https://openalex.org/W2132799343","https://openalex.org/W1982519184"],"abstract_inverted_index":{"Cold":[0],"acclimation":[1],"involves":[2],"a":[3],"number":[4],"of":[5,15,30,46,71,78,80],"different":[6],"cellular":[7,73],"processes":[8,74],"that":[9,24,65],"together":[10],"increase":[11],"the":[12,28,44,69],"freezing":[13],"tolerance":[14],"an":[16],"organism.":[17],"The":[18],"DREB1/CBFs":[19,47],"are":[20,25],"transcription":[21],"factors":[22],"(TFs)":[23],"prominent":[26],"in":[27,33,82],"regulation":[29,70],"cold":[31],"responses":[32],"Arabidopsis":[34],"thaliana,":[35],"rice":[36],"and":[37,48,63],"many":[38],"other":[39],"crops.":[40],"We":[41],"investigated":[42],"if":[43],"expression":[45],"co-expressed":[49],"genes":[50],"relies":[51],"on":[52],"combinatorial":[53],"control":[54],"by":[55],"several":[56],"TFs.":[57],"Our":[58],"results":[59],"support":[60],"this":[61],"notion":[62],"indicate":[64],"methods":[66],"for":[67,86],"studying":[68],"complex":[72],"should":[75],"include":[76],"identification":[77],"combinations":[79],"motifs,":[81],"addition":[83],"to":[84],"searching":[85],"individual":[87],"overrepresented":[88],"binding":[89],"sites.":[90]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-03-10T16:38:18.471706","created_date":"2016-06-24T00:00:00"}