{"id":"https://openalex.org/W2113942490","doi":"https://doi.org/10.1093/bioinformatics/btp018","title":"Human microRNAs co-silence in well-separated groups and have different predicted essentialities","display_name":"Human microRNAs co-silence in well-separated groups and have different predicted essentialities","publication_year":2009,"publication_date":"2009-01-08","ids":{"openalex":"https://openalex.org/W2113942490","doi":"https://doi.org/10.1093/bioinformatics/btp018","mag":"2113942490","pmid":"https://pubmed.ncbi.nlm.nih.gov/19131366"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btp018","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp018","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/8/1063/48988434/bioinformatics_25_8_1063.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/25/8/1063/48988434/bioinformatics_25_8_1063.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085003091","display_name":"G\u00e1bor Boross","orcid":"https://orcid.org/0000-0002-7208-5678"},"institutions":[{"id":"https://openalex.org/I106118109","display_name":"E\u00f6tv\u00f6s Lor\u00e1nd University","ror":"https://ror.org/01jsq2704","country_code":"HU","type":"education","lineage":["https://openalex.org/I106118109"]},{"id":"https://openalex.org/I7597260","display_name":"Hungarian Academy of Sciences","ror":"https://ror.org/02ks8qq67","country_code":"HU","type":"government","lineage":["https://openalex.org/I7597260"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"G\u00e1bor Boross","raw_affiliation_strings":["1 Department of Biological Physics, E\u00f6tv\u00f6s Lor\u00e1nd University and 2Statistical and Biological Physics Research Group and CellCom RET at the Hungarian Academy of Sciences, P\u00e1zm\u00e1ny P\u00e9ter s\u00e9t\u00e1ny 1A, H-1117 Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Biological Physics, E\u00f6tv\u00f6s Lor\u00e1nd University and 2Statistical and Biological Physics Research Group and CellCom RET at the Hungarian Academy of Sciences, P\u00e1zm\u00e1ny P\u00e9ter s\u00e9t\u00e1ny 1A, H-1117 Budapest, Hungary","institution_ids":["https://openalex.org/I7597260","https://openalex.org/I106118109"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029615222","display_name":"Katalin Orosz","orcid":null},"institutions":[{"id":"https://openalex.org/I106118109","display_name":"E\u00f6tv\u00f6s Lor\u00e1nd University","ror":"https://ror.org/01jsq2704","country_code":"HU","type":"education","lineage":["https://openalex.org/I106118109"]},{"id":"https://openalex.org/I7597260","display_name":"Hungarian Academy of Sciences","ror":"https://ror.org/02ks8qq67","country_code":"HU","type":"government","lineage":["https://openalex.org/I7597260"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Katalin Orosz","raw_affiliation_strings":["1 Department of Biological Physics, E\u00f6tv\u00f6s Lor\u00e1nd University and 2Statistical and Biological Physics Research Group and CellCom RET at the Hungarian Academy of Sciences, P\u00e1zm\u00e1ny P\u00e9ter s\u00e9t\u00e1ny 1A, H-1117 Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Biological Physics, E\u00f6tv\u00f6s Lor\u00e1nd University and 2Statistical and Biological Physics Research Group and CellCom RET at the Hungarian Academy of Sciences, P\u00e1zm\u00e1ny P\u00e9ter s\u00e9t\u00e1ny 1A, H-1117 Budapest, Hungary","institution_ids":["https://openalex.org/I7597260","https://openalex.org/I106118109"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000251403","display_name":"Ill\u00e9s J. Farkas","orcid":"https://orcid.org/0000-0001-5341-5582"},"institutions":[{"id":"https://openalex.org/I106118109","display_name":"E\u00f6tv\u00f6s Lor\u00e1nd University","ror":"https://ror.org/01jsq2704","country_code":"HU","type":"education","lineage":["https://openalex.org/I106118109"]},{"id":"https://openalex.org/I7597260","display_name":"Hungarian Academy of Sciences","ror":"https://ror.org/02ks8qq67","country_code":"HU","type":"government","lineage":["https://openalex.org/I7597260"]}],"countries":["HU"],"is_corresponding":true,"raw_author_name":"Ill\u00e9s J. Farkas","raw_affiliation_strings":["1 Department of Biological Physics, E\u00f6tv\u00f6s Lor\u00e1nd University and 2Statistical and Biological Physics Research Group and CellCom RET at the Hungarian Academy of Sciences, P\u00e1zm\u00e1ny P\u00e9ter s\u00e9t\u00e1ny 1A, H-1117 Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Department of Biological Physics, E\u00f6tv\u00f6s Lor\u00e1nd University and 2Statistical and Biological Physics Research Group and CellCom RET at the Hungarian Academy of Sciences, P\u00e1zm\u00e1ny P\u00e9ter s\u00e9t\u00e1ny 1A, H-1117 Budapest, Hungary","institution_ids":["https://openalex.org/I7597260","https://openalex.org/I106118109"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5000251403"],"corresponding_institution_ids":["https://openalex.org/I106118109","https://openalex.org/I7597260"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":1.4063,"has_fulltext":true,"cited_by_count":36,"citation_normalized_percentile":{"value":0.83565325,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"25","issue":"8","first_page":"1063","last_page":"1069"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9668999910354614,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9668999910354614,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.8286775350570679},{"id":"https://openalex.org/keywords/gene-silencing","display_name":"Gene silencing","score":0.7280576229095459},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5923709273338318},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5713105201721191},{"id":"https://openalex.org/keywords/construct","display_name":"Construct (python library)","score":0.41454583406448364},{"id":"https://openalex.org/keywords/transcription-factor","display_name":"Transcription factor","score":0.4110400080680847},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.40858370065689087},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.37269920110702515},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.32312142848968506},{"id":"https://openalex.org/keywords/computer-network","display_name":"Computer network","score":0.1299353837966919}],"concepts":[{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.8286775350570679},{"id":"https://openalex.org/C119056186","wikidata":"https://www.wikidata.org/wiki/Q1431332","display_name":"Gene silencing","level":3,"score":0.7280576229095459},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5923709273338318},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5713105201721191},{"id":"https://openalex.org/C2780801425","wikidata":"https://www.wikidata.org/wiki/Q5164392","display_name":"Construct (python library)","level":2,"score":0.41454583406448364},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.4110400080680847},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.40858370065689087},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.37269920110702515},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.32312142848968506},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.1299353837966919}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btp018","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp018","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/8/1063/48988434/bioinformatics_25_8_1063.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:19131366","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19131366","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:publicatio.bibl.u-szeged.hu:8443","is_oa":true,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306400436","display_name":"SZTE Publicatio Repozit\u00f3rium (University of Szeged)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I227486990","host_organization_name":"University of Szeged","host_organization_lineage":["https://openalex.org/I227486990"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Cikk"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btp018","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btp018","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/8/1063/48988434/bioinformatics_25_8_1063.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322193","display_name":"Nemzeti Kutat\u00e1si \u00e9s Technol\u00f3giai Hivatal","ror":"https://ror.org/03g2am276"},{"id":"https://openalex.org/F4320326184","display_name":"Hungarian Science Foundation","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2113942490.pdf","grobid_xml":"https://content.openalex.org/works/W2113942490.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W1584433563","https://openalex.org/W1644749979","https://openalex.org/W1966116761","https://openalex.org/W1975437957","https://openalex.org/W1985563073","https://openalex.org/W1988163167","https://openalex.org/W1988376520","https://openalex.org/W1990868443","https://openalex.org/W2003952411","https://openalex.org/W2017199818","https://openalex.org/W2036923470","https://openalex.org/W2046618236","https://openalex.org/W2049339234","https://openalex.org/W2051403674","https://openalex.org/W2059073003","https://openalex.org/W2059382687","https://openalex.org/W2061425021","https://openalex.org/W2065566217","https://openalex.org/W2070571588","https://openalex.org/W2075110522","https://openalex.org/W2090219560","https://openalex.org/W2103177465","https://openalex.org/W2113390076","https://openalex.org/W2120778382","https://openalex.org/W2123580197","https://openalex.org/W2125879257","https://openalex.org/W2127497651","https://openalex.org/W2128989640","https://openalex.org/W2138664009","https://openalex.org/W2138954682","https://openalex.org/W2141301071","https://openalex.org/W2149146453","https://openalex.org/W2149785901","https://openalex.org/W2159675211","https://openalex.org/W2160226189","https://openalex.org/W2160467221","https://openalex.org/W2163199119","https://openalex.org/W2163480486","https://openalex.org/W2164928285","https://openalex.org/W2165533101","https://openalex.org/W2168031686","https://openalex.org/W4251060592","https://openalex.org/W4251861354"],"related_works":["https://openalex.org/W2002128513","https://openalex.org/W2594860815","https://openalex.org/W3117169687","https://openalex.org/W2092874662","https://openalex.org/W1920354401","https://openalex.org/W2171277769","https://openalex.org/W1992607385","https://openalex.org/W2419531688","https://openalex.org/W2777367386","https://openalex.org/W2793471865"],"abstract_inverted_index":{"BACKGROUND:":[0],"Short":[1],"regulating":[2],"RNAs":[3],"guide":[4],"many":[5,148],"cellular":[6],"processes.":[7],"Compared":[8],"with":[9,135],"transcription":[10],"factor":[11],"proteins":[12],"they":[13],"appear":[14],"to":[15,110,162],"provide":[16,207],"more":[17],"specialized":[18,184],"control":[19,185],"and":[20,106,112,200,222,232,239],"their":[21],"deletions":[22],"are":[23,99],"less":[24],"frequently":[25],"lethal.":[26],"RESULTS:":[27],"We":[28,102],"find":[29],"large":[30],"differences":[31],"between":[32,71],"computationally":[33],"predicted":[34,198],"lists":[35,45],"of":[36,42,52,60,76,85,97,117,145,196,215,227],"human":[37,61],"microRNA":[38],"(miRNA)-target":[39],"pairs.":[40],"Instead":[41,116],"integrating":[43],"these":[44],"we":[46,55,82,123,177,192,206],"use":[47,103],"the":[48,57,67,72,94,104,136,151,174,183,194,212,224],"two":[49],"most":[50,199],"accurate":[51],"them.":[53],"Next,":[54],"construct":[56],"co-regulation":[58,95],"network":[59],"miRNAs":[62,98,137,218,229],"as":[63,127,146,160],"nodes":[64,88],"by":[65,187],"computing":[66],"correlation":[68],"(link":[69],"weight)":[70],"gene":[73],"silencing":[74],"scores":[75],"individual":[77],"miRNAs.":[78,188,203],"In":[79,204],"this":[80],"network,":[81],"locate":[83],"groups":[84,195],"tightly":[86],"co-regulating":[87],"(modules).":[89],"Despite":[90],"explicitly":[91],"allowing":[92],"overlaps":[93],"modules":[96,105],"well":[100],"separated.":[101],"miRNA":[107,114,126,234],"co-expression":[108,134],"data":[109],"define":[111],"compute":[113],"essentiality.":[115],"focusing":[118],"on":[119],"particular":[120],"biological":[121],"functions":[122],"identify":[124],"a":[125,132,163],"essential,":[128],"if":[129],"it":[130],"has":[131],"low":[133,213],"in":[138,155,219,237],"its":[139],"module.":[140],"This":[141],"may":[142],"be":[143],"thought":[144],"having":[147],"workers":[149],"performing":[150,166],"same":[152],"tasks":[153,168],"together":[154],"one":[156],"place":[157],"(non-essential":[158],"miRNAs)":[159],"opposed":[161],"single":[164],"worker":[165],"those":[167],"alone":[169],"(essential":[170],"miRNA).":[171],"CONCLUSIONS:":[172],"On":[173],"system":[175],"level,":[176],"quantitatively":[178],"confirm":[179],"previous":[180],"findings":[181],"about":[182],"provided":[186],"For":[189],"knock-out":[190],"tests":[191],"list":[193],"our":[197],"least":[201],"essential":[202,217],"addition,":[205],"possible":[208],"explanations":[209],"for":[210],"(i)":[211],"number":[214,226],"individually":[216],"Caenorhabdtits":[220],"elegans":[221],"(ii)":[223],"high":[225],"ubiquitous":[228],"influencing":[230],"cell":[231],"tissue-specific":[233],"expression":[235],"patterns":[236],"mouse":[238],"human.":[240]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-07-02T09:51:11.867554","created_date":"2025-10-10T00:00:00"}