{"id":"https://openalex.org/W2102813017","doi":"https://doi.org/10.1093/bioinformatics/btn616","title":"Programs for calculating the statistical powers of detecting susceptibility genes in case\u2013control studies based on multistage designs","display_name":"Programs for calculating the statistical powers of detecting susceptibility genes in case\u2013control studies based on multistage designs","publication_year":2008,"publication_date":"2008-11-28","ids":{"openalex":"https://openalex.org/W2102813017","doi":"https://doi.org/10.1093/bioinformatics/btn616","mag":"2102813017","pmid":"https://pubmed.ncbi.nlm.nih.gov/19043077"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btn616","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn616","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/2/272/16889788/btn616.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/25/2/272/16889788/btn616.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001365038","display_name":"Nobutaka Kitamura","orcid":"https://orcid.org/0000-0001-6257-3144"},"institutions":[{"id":"https://openalex.org/I4210124653","display_name":"Niigata University Medical and Dental Hospital","ror":"https://ror.org/03b0x6j22","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210124653"]},{"id":"https://openalex.org/I902853133","display_name":"University of Rajshahi","ror":"https://ror.org/05nnyr510","country_code":"BD","type":"education","lineage":["https://openalex.org/I902853133"]},{"id":"https://openalex.org/I71395657","display_name":"Niigata University","ror":"https://ror.org/04ww21r56","country_code":"JP","type":"education","lineage":["https://openalex.org/I71395657"]}],"countries":["BD","JP"],"is_corresponding":true,"raw_author_name":"Nobutaka Kitamura","raw_affiliation_strings":["1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh"],"affiliations":[{"raw_affiliation_string":"1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh","institution_ids":["https://openalex.org/I71395657","https://openalex.org/I902853133","https://openalex.org/I4210124653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113552829","display_name":"Kouhei Akazawa","orcid":null},"institutions":[{"id":"https://openalex.org/I4210124653","display_name":"Niigata University Medical and Dental Hospital","ror":"https://ror.org/03b0x6j22","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210124653"]},{"id":"https://openalex.org/I71395657","display_name":"Niigata University","ror":"https://ror.org/04ww21r56","country_code":"JP","type":"education","lineage":["https://openalex.org/I71395657"]},{"id":"https://openalex.org/I902853133","display_name":"University of Rajshahi","ror":"https://ror.org/05nnyr510","country_code":"BD","type":"education","lineage":["https://openalex.org/I902853133"]}],"countries":["BD","JP"],"is_corresponding":false,"raw_author_name":"Kouhei Akazawa","raw_affiliation_strings":["1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh"],"affiliations":[{"raw_affiliation_string":"1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh","institution_ids":["https://openalex.org/I71395657","https://openalex.org/I902853133","https://openalex.org/I4210124653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090432651","display_name":"Akinori Miyashita","orcid":"https://orcid.org/0000-0003-2508-9649"},"institutions":[{"id":"https://openalex.org/I71395657","display_name":"Niigata University","ror":"https://ror.org/04ww21r56","country_code":"JP","type":"education","lineage":["https://openalex.org/I71395657"]},{"id":"https://openalex.org/I902853133","display_name":"University of Rajshahi","ror":"https://ror.org/05nnyr510","country_code":"BD","type":"education","lineage":["https://openalex.org/I902853133"]},{"id":"https://openalex.org/I4210124653","display_name":"Niigata University Medical and Dental Hospital","ror":"https://ror.org/03b0x6j22","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210124653"]}],"countries":["BD","JP"],"is_corresponding":false,"raw_author_name":"Akinori Miyashita","raw_affiliation_strings":["1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh"],"affiliations":[{"raw_affiliation_string":"1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh","institution_ids":["https://openalex.org/I71395657","https://openalex.org/I902853133","https://openalex.org/I4210124653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005287215","display_name":"Ryozo Kuwano","orcid":null},"institutions":[{"id":"https://openalex.org/I71395657","display_name":"Niigata University","ror":"https://ror.org/04ww21r56","country_code":"JP","type":"education","lineage":["https://openalex.org/I71395657"]},{"id":"https://openalex.org/I902853133","display_name":"University of Rajshahi","ror":"https://ror.org/05nnyr510","country_code":"BD","type":"education","lineage":["https://openalex.org/I902853133"]},{"id":"https://openalex.org/I4210124653","display_name":"Niigata University Medical and Dental Hospital","ror":"https://ror.org/03b0x6j22","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210124653"]}],"countries":["BD","JP"],"is_corresponding":false,"raw_author_name":"Ryozo Kuwano","raw_affiliation_strings":["1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh"],"affiliations":[{"raw_affiliation_string":"1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh","institution_ids":["https://openalex.org/I71395657","https://openalex.org/I902853133","https://openalex.org/I4210124653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110223220","display_name":"Shin\u2010ichi Toyabe","orcid":null},"institutions":[{"id":"https://openalex.org/I71395657","display_name":"Niigata University","ror":"https://ror.org/04ww21r56","country_code":"JP","type":"education","lineage":["https://openalex.org/I71395657"]},{"id":"https://openalex.org/I4210124653","display_name":"Niigata University Medical and Dental Hospital","ror":"https://ror.org/03b0x6j22","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210124653"]},{"id":"https://openalex.org/I902853133","display_name":"University of Rajshahi","ror":"https://ror.org/05nnyr510","country_code":"BD","type":"education","lineage":["https://openalex.org/I902853133"]}],"countries":["BD","JP"],"is_corresponding":false,"raw_author_name":"Shin-ichi Toyabe","raw_affiliation_strings":["1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh"],"affiliations":[{"raw_affiliation_string":"1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh","institution_ids":["https://openalex.org/I71395657","https://openalex.org/I902853133","https://openalex.org/I4210124653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073161725","display_name":"Junichiro Nakamura","orcid":null},"institutions":[{"id":"https://openalex.org/I902853133","display_name":"University of Rajshahi","ror":"https://ror.org/05nnyr510","country_code":"BD","type":"education","lineage":["https://openalex.org/I902853133"]},{"id":"https://openalex.org/I4210124653","display_name":"Niigata University Medical and Dental Hospital","ror":"https://ror.org/03b0x6j22","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210124653"]},{"id":"https://openalex.org/I71395657","display_name":"Niigata University","ror":"https://ror.org/04ww21r56","country_code":"JP","type":"education","lineage":["https://openalex.org/I71395657"]}],"countries":["BD","JP"],"is_corresponding":false,"raw_author_name":"Junichiro Nakamura","raw_affiliation_strings":["1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh"],"affiliations":[{"raw_affiliation_string":"1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh","institution_ids":["https://openalex.org/I71395657","https://openalex.org/I902853133","https://openalex.org/I4210124653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000241687","display_name":"Norihito Nakamura","orcid":null},"institutions":[{"id":"https://openalex.org/I902853133","display_name":"University of Rajshahi","ror":"https://ror.org/05nnyr510","country_code":"BD","type":"education","lineage":["https://openalex.org/I902853133"]},{"id":"https://openalex.org/I71395657","display_name":"Niigata University","ror":"https://ror.org/04ww21r56","country_code":"JP","type":"education","lineage":["https://openalex.org/I71395657"]},{"id":"https://openalex.org/I4210124653","display_name":"Niigata University Medical and Dental Hospital","ror":"https://ror.org/03b0x6j22","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210124653"]}],"countries":["BD","JP"],"is_corresponding":false,"raw_author_name":"Norihito Nakamura","raw_affiliation_strings":["1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh"],"affiliations":[{"raw_affiliation_string":"1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh","institution_ids":["https://openalex.org/I71395657","https://openalex.org/I902853133","https://openalex.org/I4210124653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060770244","display_name":"Tatsuhiko Sato","orcid":"https://orcid.org/0000-0001-5209-3788"},"institutions":[{"id":"https://openalex.org/I4210124653","display_name":"Niigata University Medical and Dental Hospital","ror":"https://ror.org/03b0x6j22","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210124653"]},{"id":"https://openalex.org/I71395657","display_name":"Niigata University","ror":"https://ror.org/04ww21r56","country_code":"JP","type":"education","lineage":["https://openalex.org/I71395657"]},{"id":"https://openalex.org/I902853133","display_name":"University of Rajshahi","ror":"https://ror.org/05nnyr510","country_code":"BD","type":"education","lineage":["https://openalex.org/I902853133"]}],"countries":["BD","JP"],"is_corresponding":false,"raw_author_name":"Tatsuhiko Sato","raw_affiliation_strings":["1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh"],"affiliations":[{"raw_affiliation_string":"1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh","institution_ids":["https://openalex.org/I71395657","https://openalex.org/I902853133","https://openalex.org/I4210124653"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100860062","display_name":"Mominul Hoque","orcid":null},"institutions":[{"id":"https://openalex.org/I4210124653","display_name":"Niigata University Medical and Dental Hospital","ror":"https://ror.org/03b0x6j22","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210124653"]},{"id":"https://openalex.org/I71395657","display_name":"Niigata University","ror":"https://ror.org/04ww21r56","country_code":"JP","type":"education","lineage":["https://openalex.org/I71395657"]},{"id":"https://openalex.org/I902853133","display_name":"University of Rajshahi","ror":"https://ror.org/05nnyr510","country_code":"BD","type":"education","lineage":["https://openalex.org/I902853133"]}],"countries":["BD","JP"],"is_corresponding":false,"raw_author_name":"M. Aminul Hoque","raw_affiliation_strings":["1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh"],"affiliations":[{"raw_affiliation_string":"1 Department of Medical Informatics, Niigata University Medical and Dental Hospital, Niigata 951-8520, 2Genome Science Branch, Center of Bioresource-Based Researches, Brain Research Institute, Niigata University, Niigata 951-8585, Japan and 3Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh","institution_ids":["https://openalex.org/I71395657","https://openalex.org/I902853133","https://openalex.org/I4210124653"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5001365038"],"corresponding_institution_ids":["https://openalex.org/I4210124653","https://openalex.org/I71395657","https://openalex.org/I902853133"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":0.0,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.15103409,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"25","issue":"2","first_page":"272","last_page":"273"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.9944999814033508,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.9944999814033508,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9909999966621399,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/snp","display_name":"SNP","score":0.644463300704956},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5641083121299744},{"id":"https://openalex.org/keywords/false-discovery-rate","display_name":"False discovery rate","score":0.48649948835372925},{"id":"https://openalex.org/keywords/false-positive-rate","display_name":"False positive rate","score":0.4838041663169861},{"id":"https://openalex.org/keywords/genetic-association","display_name":"Genetic association","score":0.4794122874736786},{"id":"https://openalex.org/keywords/multiple-comparisons-problem","display_name":"Multiple comparisons problem","score":0.4673626124858856},{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"Genome-wide association study","score":0.4621807634830475},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.4436696171760559},{"id":"https://openalex.org/keywords/statistical-analysis","display_name":"Statistical analysis","score":0.4168369770050049},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.390741229057312},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.3686673641204834},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.36028945446014404},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3512647747993469},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.31428831815719604},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.2839452028274536},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.26834556460380554},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.15138760209083557}],"concepts":[{"id":"https://openalex.org/C139275648","wikidata":"https://www.wikidata.org/wiki/Q17134011","display_name":"SNP","level":5,"score":0.644463300704956},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5641083121299744},{"id":"https://openalex.org/C193244246","wikidata":"https://www.wikidata.org/wiki/Q5432696","display_name":"False discovery rate","level":3,"score":0.48649948835372925},{"id":"https://openalex.org/C95922358","wikidata":"https://www.wikidata.org/wiki/Q5432725","display_name":"False positive rate","level":2,"score":0.4838041663169861},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.4794122874736786},{"id":"https://openalex.org/C183905921","wikidata":"https://www.wikidata.org/wiki/Q1038757","display_name":"Multiple comparisons problem","level":2,"score":0.4673626124858856},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.4621807634830475},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4436696171760559},{"id":"https://openalex.org/C2986587452","wikidata":"https://www.wikidata.org/wiki/Q938438","display_name":"Statistical analysis","level":2,"score":0.4168369770050049},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.390741229057312},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.3686673641204834},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.36028945446014404},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3512647747993469},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31428831815719604},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.2839452028274536},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.26834556460380554},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.15138760209083557},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btn616","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn616","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/2/272/16889788/btn616.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:19043077","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19043077","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:2639008","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2639008","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btn616","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn616","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/2/272/16889788/btn616.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G12401395","display_name":null,"funder_award_id":"Technology","funder_id":"https://openalex.org/F4320320912","funder_display_name":"Ministry of Education, Culture, Sports, Science and Technology"},{"id":"https://openalex.org/G7482275571","display_name":null,"funder_award_id":"Ministry of Education, Culture, Sports, Science and Technology","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7752643416","display_name":null,"funder_award_id":"Japan","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G8044579487","display_name":null,"funder_award_id":"Japan","funder_id":"https://openalex.org/F4320320912","funder_display_name":"Ministry of Education, Culture, Sports, Science and Technology"}],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2102813017.pdf","grobid_xml":"https://content.openalex.org/works/W2102813017.grobid-xml"},"referenced_works_count":7,"referenced_works":["https://openalex.org/W1479823809","https://openalex.org/W1993105887","https://openalex.org/W2061750459","https://openalex.org/W2140126911","https://openalex.org/W2148356968","https://openalex.org/W2160138207","https://openalex.org/W4242068035"],"related_works":["https://openalex.org/W2145006442","https://openalex.org/W2132004093","https://openalex.org/W2079415229","https://openalex.org/W2167743729","https://openalex.org/W2808987028","https://openalex.org/W2322154483","https://openalex.org/W3098957855","https://openalex.org/W4321092570","https://openalex.org/W2345055150","https://openalex.org/W2941123918"],"abstract_inverted_index":{"We":[0],"developed":[1],"programs":[2,44,58],"for":[3],"a":[4,69],"multistage":[5],"case-control":[6],"association":[7,71],"study":[8],"using":[9],"R":[10],"language.":[11],"In":[12],"our":[13],"programs,":[14],"input":[15],"parameters":[16],"include":[17],"numbers":[18,50],"of":[19,30,51],"samples":[20,31],"and":[21,28,32,49],"candidate":[22],"loci,":[23],"genome-wide":[24,70],"false":[25],"positive":[26],"rate":[27],"proportions":[29],"loci":[33],"to":[34,61],"be":[35],"selected":[36],"at":[37],"the":[38],"k-th":[39],"stage":[40],"(k=1,...,":[41],"n).":[42],"The":[43,57],"output":[45],"statistical":[46],"powers,":[47],"PPVs":[48],"typings":[52],"in":[53,67],"arbitrary":[54],"n-stage":[55],"designs.":[56],"can":[59],"contribute":[60],"prior":[62],"simulations":[63],"under":[64],"various":[65],"conditions":[66],"planning":[68],"study.":[72]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}