{"id":"https://openalex.org/W2108403321","doi":"https://doi.org/10.1093/bioinformatics/btn610","title":"Detecting glycan cancer biomarkers in serum samples using MALDI FT-ICR mass spectrometry data","display_name":"Detecting glycan cancer biomarkers in serum samples using MALDI FT-ICR mass spectrometry data","publication_year":2008,"publication_date":"2008-12-09","ids":{"openalex":"https://openalex.org/W2108403321","doi":"https://doi.org/10.1093/bioinformatics/btn610","mag":"2108403321","pmid":"https://pubmed.ncbi.nlm.nih.gov/19073586"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btn610","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn610","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/2/251/48982493/bioinformatics_25_2_251.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/25/2/251/48982493/bioinformatics_25_2_251.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027865998","display_name":"Donald A. Barkauskas","orcid":"https://orcid.org/0000-0002-2339-719X"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Donald A. Barkauskas","raw_affiliation_strings":["1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071147220","display_name":"Hyun Joo An","orcid":"https://orcid.org/0000-0001-5847-7483"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hyun Joo An","raw_affiliation_strings":["1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003337365","display_name":"Scott Kronewitter","orcid":null},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott R. Kronewitter","raw_affiliation_strings":["1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074821821","display_name":"Maria Lorna A. De Leoz","orcid":"https://orcid.org/0000-0001-9846-5524"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maria Lorna de Leoz","raw_affiliation_strings":["1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111560865","display_name":"Helen K. Chew","orcid":null},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Helen K. Chew","raw_affiliation_strings":["1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111100199","display_name":"Ralph W. de Vere White","orcid":null},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ralph W. de Vere White","raw_affiliation_strings":["1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012301401","display_name":"Gary S. Leiserowitz","orcid":"https://orcid.org/0000-0002-3016-4490"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary S. Leiserowitz","raw_affiliation_strings":["1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001952491","display_name":"Suzanne Miyamoto","orcid":"https://orcid.org/0000-0001-8672-4082"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suzanne Miyamoto","raw_affiliation_strings":["1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073121510","display_name":"Carlito B. Lebrilla","orcid":"https://orcid.org/0000-0001-7190-5323"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carlito B. Lebrilla","raw_affiliation_strings":["1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059478677","display_name":"David M. Rocke","orcid":"https://orcid.org/0000-0002-3958-7318"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David M. Rocke","raw_affiliation_strings":["1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Graduate Group in Biostatistics with a Designated Emphasis in Biotechnology, 2Department of Chemistry, 3Cancer Center, Division of Hematology/Oncology, 4Cancer Center, Division of Urology, 5Cancer Center, Division of Gynecologic Oncology and 6Division of Biostatistics, School of Medicine, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5027865998"],"corresponding_institution_ids":["https://openalex.org/I84218800"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":2.266,"has_fulltext":true,"cited_by_count":38,"citation_normalized_percentile":{"value":0.87349477,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"25","issue":"2","first_page":"251","last_page":"257"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":0.5031999945640564,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":0.5031999945640564,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.3856000006198883,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.023399999365210533,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mass-spectrometry","display_name":"Mass spectrometry","score":0.7284876704216003},{"id":"https://openalex.org/keywords/glycan","display_name":"Glycan","score":0.6530270576477051},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.531780481338501},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.4307108223438263},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.1550915539264679}],"concepts":[{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.7284876704216003},{"id":"https://openalex.org/C206212055","wikidata":"https://www.wikidata.org/wiki/Q2553138","display_name":"Glycan","level":3,"score":0.6530270576477051},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.531780481338501},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4307108223438263},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1550915539264679},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005583","descriptor_name":"Fourier Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005583","descriptor_name":"Fourier Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005583","descriptor_name":"Fourier Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005583","descriptor_name":"Fourier Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D017357","descriptor_name":"Cyclotrons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017357","descriptor_name":"Cyclotrons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017357","descriptor_name":"Cyclotrons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017357","descriptor_name":"Cyclotrons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019032","descriptor_name":"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D019032","descriptor_name":"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D019032","descriptor_name":"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D019032","descriptor_name":"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D019032","descriptor_name":"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019032","descriptor_name":"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019032","descriptor_name":"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019032","descriptor_name":"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btn610","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn610","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/2/251/48982493/bioinformatics_25_2_251.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2639011","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2639011","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"Text"},{"id":"pmid:19073586","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19073586","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.954.5769","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.954.5769","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://bioinformatics.oxfordjournals.org/content/early/2008/12/09/bioinformatics.btn610.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btn610","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn610","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/25/2/251/48982493/bioinformatics_25_2_251.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6800000071525574,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G1251846919","display_name":null,"funder_award_id":"P42-ES-04699","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"},{"id":"https://openalex.org/G1334777067","display_name":null,"funder_award_id":"R01GM049077","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G1391826656","display_name":null,"funder_award_id":"2-T32-GM08799","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G1833674878","display_name":null,"funder_award_id":"W81XWH-06-1-0011","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1915901823","display_name":null,"funder_award_id":"T32-GM008799","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2136317835","display_name":"NRSA Training","funder_award_id":"5p42es004699-33","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2203174199","display_name":null,"funder_award_id":"R01-GM49077","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2366971526","display_name":null,"funder_award_id":"P42 ES004699","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"},{"id":"https://openalex.org/G4119534169","display_name":null,"funder_award_id":"W81XWH","funder_id":"https://openalex.org/F4320306078","funder_display_name":"U.S. Department of Defense"},{"id":"https://openalex.org/G5341433545","display_name":null,"funder_award_id":"P30-CA93373","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5609090957","display_name":null,"funder_award_id":"R01 HG003352","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G5850682332","display_name":null,"funder_award_id":"W81XWH","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6032559747","display_name":null,"funder_award_id":"P30CA93373-AV-96","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G776903742","display_name":null,"funder_award_id":"P30-CA093373","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320306078","display_name":"U.S. Department of Defense","ror":"https://ror.org/0447fe631"},{"id":"https://openalex.org/F4320312848","display_name":"National Ovarian Cancer Coalition","ror":"https://ror.org/03exev935"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"},{"id":"https://openalex.org/F4320338485","display_name":"DOD Prostate Cancer Research Program","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2108403321.pdf","grobid_xml":"https://content.openalex.org/works/W2108403321.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W39108978","https://openalex.org/W652805531","https://openalex.org/W1480803047","https://openalex.org/W1589643407","https://openalex.org/W1897052165","https://openalex.org/W1979087564","https://openalex.org/W1994710495","https://openalex.org/W2006088684","https://openalex.org/W2062302478","https://openalex.org/W2082386502","https://openalex.org/W2094171036","https://openalex.org/W2100275703","https://openalex.org/W2106879981","https://openalex.org/W2110065044","https://openalex.org/W2139368593","https://openalex.org/W2150312232","https://openalex.org/W3189313910","https://openalex.org/W6635259870"],"related_works":["https://openalex.org/W4387497383","https://openalex.org/W2948807893","https://openalex.org/W2778153218","https://openalex.org/W2748952813","https://openalex.org/W1531601525","https://openalex.org/W2078814861","https://openalex.org/W2527526854","https://openalex.org/W1976181487","https://openalex.org/W1986764834","https://openalex.org/W657579294"],"abstract_inverted_index":{"Abstract":[0],"Motivation:":[1],"The":[2,68,119,174],"development":[3],"of":[4,16,98,112,131,170,190],"better":[5],"tests":[6,28],"to":[7,53,105,125,157,177],"detect":[8],"cancer":[9,61,113,143,164,171],"in":[10,21,70,128,145,166,182,187],"its":[11],"earliest":[12],"stages":[13],"is":[14,185],"one":[15],"the":[17,48,129,179,188,200,208],"most":[18],"sought-after":[19],"goals":[20],"medicine.":[22],"Especially":[23],"important":[24],"are":[25],"minimally":[26],"invasive":[27],"that":[29,57,154],"require":[30],"only":[31],"blood":[32,49,66],"or":[33,206],"urine":[34],"samples.":[35],"By":[36],"profiling":[37],"oligosaccharides":[38],"cleaved":[39],"from":[40,108,199,207],"glycosylated":[41],"proteins":[42],"shed":[43],"by":[44],"tumor":[45],"cells":[46],"into":[47],"stream,":[50],"we":[51,121],"hope":[52],"determine":[54],"glycan":[55],"profiles":[56],"will":[58],"help":[59],"identify":[60],"patients":[62],"using":[63,75],"a":[64],"simple":[65],"test.":[67],"data":[69,101],"this":[71,96,183],"article":[72,184],"were":[73,155],"generated":[74],"matrix-assisted":[76],"laser":[77],"desorption/ionization":[78],"Fourier":[79],"transform":[80],"ion":[81],"cyclotron":[82],"resonance":[83],"mass":[84,99],"spectrometry":[85,100],"(MALDI":[86],"FT-ICR":[87,133],"MS).":[88],"We":[89,136],"have":[90,122],"developed":[91,123],"novel":[92],"methods":[93],"for":[94],"analyzing":[95],"type":[97],"and":[102,116,142,163],"applied":[103],"it":[104],"eight":[106,147],"datasets":[107],"three":[109,168],"different":[110,160],"types":[111,169],"(breast,":[114],"ovarian":[115],"prostate).":[117],"Results:":[118],"techniques":[120],"appear":[124],"be":[126,158],"effective":[127],"analysis":[130,180],"MALDI":[132],"MS":[134],"data.":[135],"found":[137,156],"significant":[138],"differences":[139],"between":[140,161],"control":[141,162],"groups":[144,165],"all":[146,167],"datasets,":[148],"including":[149],"two":[150],"structurally":[151],"related":[152],"compounds":[153],"significantly":[159],"studied.":[172],"Availability:":[173],"software":[175],"used":[176],"perform":[178],"described":[181],"available":[186],"form":[189],"an":[191],"R":[192,202],"package":[193],"called":[194],"fticrms,":[195],"version":[196],"0.6,":[197],"either":[198],"Comprehensive":[201],"Archive":[203],"Network":[204],"(http://www.r-project.org/)":[205],"first":[209],"author.":[210],"Contact:":[211],"barkda@wald.ucdavis.edu":[212]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":7}],"updated_date":"2026-08-11T07:18:39.950985","created_date":"2025-10-10T00:00:00"}