{"id":"https://openalex.org/W2123059674","doi":"https://doi.org/10.1093/bioinformatics/btn547","title":"Effective cluster-based seed design for cross-species sequence comparisons","display_name":"Effective cluster-based seed design for cross-species sequence comparisons","publication_year":2008,"publication_date":"2008-10-20","ids":{"openalex":"https://openalex.org/W2123059674","doi":"https://doi.org/10.1093/bioinformatics/btn547","mag":"2123059674","pmid":"https://pubmed.ncbi.nlm.nih.gov/18940827"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btn547","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn547","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/24/24/2926/49056007/bioinformatics_24_24_2926.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/24/24/2926/49056007/bioinformatics_24_24_2926.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053701097","display_name":"Leming Zhou","orcid":"https://orcid.org/0000-0003-4398-0267"},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Leming Zhou","raw_affiliation_strings":["Department of Computer Science, George Washington University, Washington DC 20052, USA","[Department of Computer Science, George Washington University, Washington, DC 20052, USA]"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, George Washington University, Washington DC 20052, USA","institution_ids":["https://openalex.org/I193531525"]},{"raw_affiliation_string":"[Department of Computer Science, George Washington University, Washington, DC 20052, USA]","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020460086","display_name":"Ingrid Mihai","orcid":null},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ingrid Mihai","raw_affiliation_strings":["Department of Computer Science, George Washington University, Washington DC 20052, USA","[Department of Computer Science, George Washington University, Washington, DC 20052, USA]"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, George Washington University, Washington DC 20052, USA","institution_ids":["https://openalex.org/I193531525"]},{"raw_affiliation_string":"[Department of Computer Science, George Washington University, Washington, DC 20052, USA]","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065946017","display_name":"Liliana Florea","orcid":"https://orcid.org/0000-0001-8124-2324"},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Liliana Florea","raw_affiliation_strings":["Department of Computer Science, George Washington University, Washington DC 20052, USA","[Department of Computer Science, George Washington University, Washington, DC 20052, USA]"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, George Washington University, Washington DC 20052, USA","institution_ids":["https://openalex.org/I193531525"]},{"raw_affiliation_string":"[Department of Computer Science, George Washington University, Washington, DC 20052, USA]","institution_ids":["https://openalex.org/I193531525"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5053701097"],"corresponding_institution_ids":["https://openalex.org/I193531525"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.404,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.63760796,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"24","issue":"24","first_page":"2926","last_page":"2927"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pairwise-comparison","display_name":"Pairwise comparison","score":0.8101649284362793},{"id":"https://openalex.org/keywords/closeness","display_name":"Closeness","score":0.8072299957275391},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.5953285098075867},{"id":"https://openalex.org/keywords/cluster","display_name":"Cluster (spacecraft)","score":0.5545010566711426},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.554336667060852},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.47944775223731995},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4713049829006195},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.46184343099594116},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4513319432735443},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.42390722036361694},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.40145382285118103},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.31088316440582275},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2134791910648346},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.17292547225952148},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.15683495998382568}],"concepts":[{"id":"https://openalex.org/C184898388","wikidata":"https://www.wikidata.org/wiki/Q1435712","display_name":"Pairwise comparison","level":2,"score":0.8101649284362793},{"id":"https://openalex.org/C2779545769","wikidata":"https://www.wikidata.org/wiki/Q5135364","display_name":"Closeness","level":2,"score":0.8072299957275391},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5953285098075867},{"id":"https://openalex.org/C164866538","wikidata":"https://www.wikidata.org/wiki/Q367351","display_name":"Cluster (spacecraft)","level":2,"score":0.5545010566711426},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.554336667060852},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.47944775223731995},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4713049829006195},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.46184343099594116},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4513319432735443},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.42390722036361694},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.40145382285118103},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.31088316440582275},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2134791910648346},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.17292547225952148},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.15683495998382568},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btn547","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn547","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/24/24/2926/49056007/bioinformatics_24_24_2926.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:18940827","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18940827","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btn547","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn547","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/24/24/2926/49056007/bioinformatics_24_24_2926.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15","score":0.5600000023841858}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2123059674.pdf","grobid_xml":"https://content.openalex.org/works/W2123059674.grobid-xml"},"referenced_works_count":10,"referenced_works":["https://openalex.org/W1992209615","https://openalex.org/W2043615998","https://openalex.org/W2047794824","https://openalex.org/W2055043387","https://openalex.org/W2099111195","https://openalex.org/W2101664494","https://openalex.org/W2109692166","https://openalex.org/W2128591967","https://openalex.org/W2133903964","https://openalex.org/W6643069710"],"related_works":["https://openalex.org/W2487539810","https://openalex.org/W2351540725","https://openalex.org/W1603543036","https://openalex.org/W2735639039","https://openalex.org/W2148556617","https://openalex.org/W142583359","https://openalex.org/W2950239980","https://openalex.org/W2169501356","https://openalex.org/W3032097558","https://openalex.org/W3014856251"],"abstract_inverted_index":{"Source":[0],"code":[1],"is":[2],"freely":[3],"available":[4],"at":[5],"http://dna.cs.gwu.edu":[6],"and":[7],"from":[8],"Bioinformatics":[9],"online.":[10]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}