{"id":"https://openalex.org/W2128427913","doi":"https://doi.org/10.1093/bioinformatics/btn489","title":"Functional modules integrating essential cellular functions are predictive of the response of leukaemia cells to DNA damage","display_name":"Functional modules integrating essential cellular functions are predictive of the response of leukaemia cells to DNA damage","publication_year":2008,"publication_date":"2008-09-17","ids":{"openalex":"https://openalex.org/W2128427913","doi":"https://doi.org/10.1093/bioinformatics/btn489","mag":"2128427913","pmid":"https://pubmed.ncbi.nlm.nih.gov/18801750"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btn489","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn489","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084170818","display_name":"Katrin Sameith","orcid":"https://orcid.org/0000-0003-4306-930X"},"institutions":[{"id":"https://openalex.org/I105862471","display_name":"Biomax Informatics (Germany)","ror":"https://ror.org/02h1y5y54","country_code":"DE","type":"company","lineage":["https://openalex.org/I105862471"]},{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["DE","GB"],"is_corresponding":false,"raw_author_name":"Katrin Sameith","raw_affiliation_strings":["1 School of Biosciences and Institute of Biomedical Research (IBR), 2CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, B152TT, UK and 3Biomax Informatics AG, Lochhamer Str. 9, 82152 Martinsried, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 School of Biosciences and Institute of Biomedical Research (IBR), 2CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, B152TT, UK and 3Biomax Informatics AG, Lochhamer Str. 9, 82152 Martinsried, Germany","institution_ids":["https://openalex.org/I105862471","https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037629923","display_name":"Philipp Antczak","orcid":"https://orcid.org/0000-0001-9600-7757"},"institutions":[{"id":"https://openalex.org/I105862471","display_name":"Biomax Informatics (Germany)","ror":"https://ror.org/02h1y5y54","country_code":"DE","type":"company","lineage":["https://openalex.org/I105862471"]},{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["DE","GB"],"is_corresponding":false,"raw_author_name":"Philipp Antczak","raw_affiliation_strings":["1 School of Biosciences and Institute of Biomedical Research (IBR), 2CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, B152TT, UK and 3Biomax Informatics AG, Lochhamer Str. 9, 82152 Martinsried, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 School of Biosciences and Institute of Biomedical Research (IBR), 2CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, B152TT, UK and 3Biomax Informatics AG, Lochhamer Str. 9, 82152 Martinsried, Germany","institution_ids":["https://openalex.org/I105862471","https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083818358","display_name":"Elliot Marston","orcid":null},"institutions":[{"id":"https://openalex.org/I105862471","display_name":"Biomax Informatics (Germany)","ror":"https://ror.org/02h1y5y54","country_code":"DE","type":"company","lineage":["https://openalex.org/I105862471"]},{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["DE","GB"],"is_corresponding":false,"raw_author_name":"Elliot Marston","raw_affiliation_strings":["1 School of Biosciences and Institute of Biomedical Research (IBR), 2CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, B152TT, UK and 3Biomax Informatics AG, Lochhamer Str. 9, 82152 Martinsried, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 School of Biosciences and Institute of Biomedical Research (IBR), 2CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, B152TT, UK and 3Biomax Informatics AG, Lochhamer Str. 9, 82152 Martinsried, Germany","institution_ids":["https://openalex.org/I105862471","https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102841226","display_name":"Nil Turan","orcid":"https://orcid.org/0000-0002-6841-4395"},"institutions":[{"id":"https://openalex.org/I105862471","display_name":"Biomax Informatics (Germany)","ror":"https://ror.org/02h1y5y54","country_code":"DE","type":"company","lineage":["https://openalex.org/I105862471"]},{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["DE","GB"],"is_corresponding":false,"raw_author_name":"Nil Turan","raw_affiliation_strings":["1 School of Biosciences and Institute of Biomedical Research (IBR), 2CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, B152TT, UK and 3Biomax Informatics AG, Lochhamer Str. 9, 82152 Martinsried, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 School of Biosciences and Institute of Biomedical Research (IBR), 2CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, B152TT, UK and 3Biomax Informatics AG, Lochhamer Str. 9, 82152 Martinsried, Germany","institution_ids":["https://openalex.org/I105862471","https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061376775","display_name":"Dieter Maier","orcid":"https://orcid.org/0000-0003-4460-0959"},"institutions":[{"id":"https://openalex.org/I105862471","display_name":"Biomax Informatics (Germany)","ror":"https://ror.org/02h1y5y54","country_code":"DE","type":"company","lineage":["https://openalex.org/I105862471"]},{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["DE","GB"],"is_corresponding":false,"raw_author_name":"Dieter Maier","raw_affiliation_strings":["1 School of Biosciences and Institute of Biomedical Research (IBR), 2CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, B152TT, UK and 3Biomax Informatics AG, Lochhamer Str. 9, 82152 Martinsried, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 School of Biosciences and Institute of Biomedical Research (IBR), 2CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, B152TT, UK and 3Biomax Informatics AG, Lochhamer Str. 9, 82152 Martinsried, Germany","institution_ids":["https://openalex.org/I105862471","https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Tanja Stankovic","orcid":null},"institutions":[{"id":"https://openalex.org/I105862471","display_name":"Biomax Informatics (Germany)","ror":"https://ror.org/02h1y5y54","country_code":"DE","type":"company","lineage":["https://openalex.org/I105862471"]},{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["DE","GB"],"is_corresponding":false,"raw_author_name":"Tanja Stankovic","raw_affiliation_strings":["1 School of Biosciences and Institute of Biomedical Research (IBR), 2CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, B152TT, UK and 3Biomax Informatics AG, Lochhamer Str. 9, 82152 Martinsried, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 School of Biosciences and Institute of Biomedical Research (IBR), 2CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, B152TT, UK and 3Biomax Informatics AG, Lochhamer Str. 9, 82152 Martinsried, Germany","institution_ids":["https://openalex.org/I105862471","https://openalex.org/I79619799"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082775010","display_name":"Francesco Falciani","orcid":"https://orcid.org/0000-0003-1432-2871"},"institutions":[{"id":"https://openalex.org/I105862471","display_name":"Biomax Informatics (Germany)","ror":"https://ror.org/02h1y5y54","country_code":"DE","type":"company","lineage":["https://openalex.org/I105862471"]},{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["DE","GB"],"is_corresponding":true,"raw_author_name":"Francesco Falciani","raw_affiliation_strings":["1 School of Biosciences and Institute of Biomedical Research (IBR), 2CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, B152TT, UK and 3Biomax Informatics AG, Lochhamer Str. 9, 82152 Martinsried, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 School of Biosciences and Institute of Biomedical Research (IBR), 2CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, B152TT, UK and 3Biomax Informatics AG, Lochhamer Str. 9, 82152 Martinsried, Germany","institution_ids":["https://openalex.org/I105862471","https://openalex.org/I79619799"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5082775010"],"corresponding_institution_ids":["https://openalex.org/I105862471","https://openalex.org/I79619799"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.702,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.70937459,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"24","issue":"22","first_page":"2602","last_page":"2607"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.1597999930381775,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.1597999930381775,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12534","display_name":"Protein Degradation and Inhibitors","score":0.06750000268220901,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.04560000076889992,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-damage","display_name":"DNA damage","score":0.803026556968689},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5962545275688171},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.4837610721588135},{"id":"https://openalex.org/keywords/malignancy","display_name":"Malignancy","score":0.4505603015422821},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4502220153808594},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3777892589569092},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.37045156955718994},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2145695686340332}],"concepts":[{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.803026556968689},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5962545275688171},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4837610721588135},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.4505603015422821},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4502220153808594},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3777892589569092},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.37045156955718994},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2145695686340332}],"mesh":[{"descriptor_ui":"D002051","descriptor_name":"Burkitt Lymphoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002051","descriptor_name":"Burkitt Lymphoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002051","descriptor_name":"Burkitt Lymphoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002051","descriptor_name":"Burkitt Lymphoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002051","descriptor_name":"Burkitt Lymphoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002051","descriptor_name":"Burkitt Lymphoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btn489","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn489","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:18801750","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18801750","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/80d7b5d7-618f-4365-8d82-e3c791a878ff","is_oa":false,"landing_page_url":"https://research.birmingham.ac.uk/en/publications/80d7b5d7-618f-4365-8d82-e3c791a878ff","pdf_url":null,"source":{"id":"https://openalex.org/S4306402634","display_name":"University of Birmingham Research Portal (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Sameith, K, Antczak, P, Marston, E, Turan Jurdzinski, N, Maier, D, Stankovic, T & Falciani, F 2008, 'Functional modules integrating essential cellular functions are predictive of the response of leukaemia cells to DNA damage.', Bioinformatics, vol. 24, no. 22, pp. 2602-7. https://doi.org/10.1093/bioinformatics/btn489","raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8399999737739563,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G2630651272","display_name":null,"funder_award_id":"BB/D524624/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G4167096278","display_name":"High Throughput Systems Biology Analysis Modelling and Stimulation of Large Biological Data Sets","funder_award_id":"BB/D524624/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G909617130","display_name":null,"funder_award_id":"S20214","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1586778826","https://openalex.org/W1644749979","https://openalex.org/W1876024155","https://openalex.org/W2016978704","https://openalex.org/W2084833542","https://openalex.org/W2087240661","https://openalex.org/W2097795961","https://openalex.org/W2098421151","https://openalex.org/W2106552363","https://openalex.org/W2112811019","https://openalex.org/W2128941558","https://openalex.org/W2131323902","https://openalex.org/W2136850043","https://openalex.org/W2138218344","https://openalex.org/W2154687435","https://openalex.org/W2154697046","https://openalex.org/W2161409973","https://openalex.org/W2165207521","https://openalex.org/W2167190345","https://openalex.org/W2171776966","https://openalex.org/W4302422232","https://openalex.org/W6679238049"],"related_works":["https://openalex.org/W2028633235","https://openalex.org/W2769377618","https://openalex.org/W2112881545","https://openalex.org/W4283706870","https://openalex.org/W2424758321","https://openalex.org/W2003457467","https://openalex.org/W1499193777","https://openalex.org/W2091594449","https://openalex.org/W2061904323","https://openalex.org/W2111026114"],"abstract_inverted_index":{"MOTIVATION:":[0],"Childhood":[1],"B-precursor":[2],"lymphoblastic":[3],"leukaemia":[4],"(ALL)":[5],"is":[6,29,130],"the":[7,13,24,48,71,82,92,106,118,154],"most":[8],"common":[9],"paediatric":[10],"malignancy.":[11],"Despite":[12],"fact":[14],"that":[15,37,84,117],"80%":[16],"of":[17,26,108,121,132,153],"ALL":[18,112],"patients":[19],"respond":[20],"to":[21,53,74,80,94,134],"anti-cancer":[22],"drugs,":[23],"patho-physiology":[25],"this":[27],"disease":[28],"still":[30],"not":[31,42],"fully":[32],"understood.":[33],"mRNA":[34,128],"expression-profiling":[35],"studies":[36],"have":[38,41,98,115],"been":[39],"performed":[40],"yet":[43],"provided":[44],"novel":[45,66,103],"insights":[46],"into":[47],"mechanisms":[49],"behind":[50],"cellular":[51,72],"response":[52,93,133],"DNA":[54,75,95,135],"damage.":[55,76,136],"More":[56],"powerful":[57],"data":[58,163],"analysis":[59],"techniques":[60],"may":[61,88],"be":[62,89],"required":[63],"for":[64,105],"identifying":[65],"functional":[67,109,122],"pathways":[68],"involved":[69,90],"in":[70,91,111],"responses":[73],"RESULTS:":[77],"In":[78],"order":[79],"explore":[81],"possibility":[83],"unforeseen":[85],"biological":[86],"processes":[87],"damage,":[96],"we":[97],"developed":[99],"and":[100,127],"applied":[101],"a":[102,150],"procedure":[104],"identification":[107],"modules":[110,123],"cells.":[113],"We":[114],"discovered":[116],"overall":[119],"activity":[120],"integrating":[124],"protein":[125],"degradation":[126],"processing":[129],"predictive":[131],"AVAILABILITY:":[137],"Supplementary":[138,162],"material":[139],"including":[140],"R":[141],"code,":[142],"additional":[143],"results,":[144],"experimental":[145],"datasets,":[146],"as":[147,149],"well":[148],"detailed":[151],"description":[152],"methodology":[155],"are":[156,164],"available":[157,165],"at":[158,166],"http://www.bip.bham.ac.uk/vivo/fumo.html.":[159],"SUPPLEMENTARY":[160],"INFORMATION:":[161],"Bioinformatics":[167],"online.":[168]},"counts_by_year":[{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4}],"updated_date":"2026-06-23T06:36:01.041984","created_date":"2025-10-10T00:00:00"}
