{"id":"https://openalex.org/W2139237500","doi":"https://doi.org/10.1093/bioinformatics/btn382","title":"Optimizing amino acid groupings for GPCR classification","display_name":"Optimizing amino acid groupings for GPCR classification","publication_year":2008,"publication_date":"2008-08-01","ids":{"openalex":"https://openalex.org/W2139237500","doi":"https://doi.org/10.1093/bioinformatics/btn382","mag":"2139237500","pmid":"https://pubmed.ncbi.nlm.nih.gov/18676973"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btn382","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn382","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/24/18/1980/476828/btn382.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/24/18/1980/476828/btn382.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103363322","display_name":"Matthew N. Davies","orcid":null},"institutions":[{"id":"https://openalex.org/I20581793","display_name":"University of Kent","ror":"https://ror.org/00xkeyj56","country_code":"GB","type":"education","lineage":["https://openalex.org/I20581793"]},{"id":"https://openalex.org/I52099693","display_name":"University of York","ror":"https://ror.org/04m01e293","country_code":"GB","type":"education","lineage":["https://openalex.org/I52099693"]},{"id":"https://openalex.org/I4210153742","display_name":"Jenner Institute","ror":"https://ror.org/05kwhph67","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210153742"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Matthew N. Davies","raw_affiliation_strings":["1 Edward Jenner Institute, Compton, Newbury, Berkshire, RG20 7NN, 2Department of Computing and Centre for BioMedical Informatics, University of Kent, Canterbury, Kent CT2 7NF and 3Departments of Computer Science and Electronics, University of York, Heslington, York YO10 5DD, UK"],"affiliations":[{"raw_affiliation_string":"1 Edward Jenner Institute, Compton, Newbury, Berkshire, RG20 7NN, 2Department of Computing and Centre for BioMedical Informatics, University of Kent, Canterbury, Kent CT2 7NF and 3Departments of Computer Science and Electronics, University of York, Heslington, York YO10 5DD, UK","institution_ids":["https://openalex.org/I4210153742","https://openalex.org/I20581793","https://openalex.org/I52099693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061536215","display_name":"Andrew Secker","orcid":null},"institutions":[{"id":"https://openalex.org/I52099693","display_name":"University of York","ror":"https://ror.org/04m01e293","country_code":"GB","type":"education","lineage":["https://openalex.org/I52099693"]},{"id":"https://openalex.org/I20581793","display_name":"University of Kent","ror":"https://ror.org/00xkeyj56","country_code":"GB","type":"education","lineage":["https://openalex.org/I20581793"]},{"id":"https://openalex.org/I4210153742","display_name":"Jenner Institute","ror":"https://ror.org/05kwhph67","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210153742"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew Secker","raw_affiliation_strings":["1 Edward Jenner Institute, Compton, Newbury, Berkshire, RG20 7NN, 2Department of Computing and Centre for BioMedical Informatics, University of Kent, Canterbury, Kent CT2 7NF and 3Departments of Computer Science and Electronics, University of York, Heslington, York YO10 5DD, UK"],"affiliations":[{"raw_affiliation_string":"1 Edward Jenner Institute, Compton, Newbury, Berkshire, RG20 7NN, 2Department of Computing and Centre for BioMedical Informatics, University of Kent, Canterbury, Kent CT2 7NF and 3Departments of Computer Science and Electronics, University of York, Heslington, York YO10 5DD, UK","institution_ids":["https://openalex.org/I4210153742","https://openalex.org/I20581793","https://openalex.org/I52099693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087201377","display_name":"Alex A. Freitas","orcid":"https://orcid.org/0000-0001-9825-4700"},"institutions":[{"id":"https://openalex.org/I52099693","display_name":"University of York","ror":"https://ror.org/04m01e293","country_code":"GB","type":"education","lineage":["https://openalex.org/I52099693"]},{"id":"https://openalex.org/I4210153742","display_name":"Jenner Institute","ror":"https://ror.org/05kwhph67","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210153742"]},{"id":"https://openalex.org/I20581793","display_name":"University of Kent","ror":"https://ror.org/00xkeyj56","country_code":"GB","type":"education","lineage":["https://openalex.org/I20581793"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alex A. Freitas","raw_affiliation_strings":["1 Edward Jenner Institute, Compton, Newbury, Berkshire, RG20 7NN, 2Department of Computing and Centre for BioMedical Informatics, University of Kent, Canterbury, Kent CT2 7NF and 3Departments of Computer Science and Electronics, University of York, Heslington, York YO10 5DD, UK"],"affiliations":[{"raw_affiliation_string":"1 Edward Jenner Institute, Compton, Newbury, Berkshire, RG20 7NN, 2Department of Computing and Centre for BioMedical Informatics, University of Kent, Canterbury, Kent CT2 7NF and 3Departments of Computer Science and Electronics, University of York, Heslington, York YO10 5DD, UK","institution_ids":["https://openalex.org/I4210153742","https://openalex.org/I20581793","https://openalex.org/I52099693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111461727","display_name":"Edward Clark","orcid":null},"institutions":[{"id":"https://openalex.org/I20581793","display_name":"University of Kent","ror":"https://ror.org/00xkeyj56","country_code":"GB","type":"education","lineage":["https://openalex.org/I20581793"]},{"id":"https://openalex.org/I4210153742","display_name":"Jenner Institute","ror":"https://ror.org/05kwhph67","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210153742"]},{"id":"https://openalex.org/I52099693","display_name":"University of York","ror":"https://ror.org/04m01e293","country_code":"GB","type":"education","lineage":["https://openalex.org/I52099693"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Edward Clark","raw_affiliation_strings":["1 Edward Jenner Institute, Compton, Newbury, Berkshire, RG20 7NN, 2Department of Computing and Centre for BioMedical Informatics, University of Kent, Canterbury, Kent CT2 7NF and 3Departments of Computer Science and Electronics, University of York, Heslington, York YO10 5DD, UK"],"affiliations":[{"raw_affiliation_string":"1 Edward Jenner Institute, Compton, Newbury, Berkshire, RG20 7NN, 2Department of Computing and Centre for BioMedical Informatics, University of Kent, Canterbury, Kent CT2 7NF and 3Departments of Computer Science and Electronics, University of York, Heslington, York YO10 5DD, UK","institution_ids":["https://openalex.org/I4210153742","https://openalex.org/I20581793","https://openalex.org/I52099693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080582720","display_name":"Jon Timmis","orcid":"https://orcid.org/0000-0003-1055-0471"},"institutions":[{"id":"https://openalex.org/I20581793","display_name":"University of Kent","ror":"https://ror.org/00xkeyj56","country_code":"GB","type":"education","lineage":["https://openalex.org/I20581793"]},{"id":"https://openalex.org/I4210153742","display_name":"Jenner Institute","ror":"https://ror.org/05kwhph67","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210153742"]},{"id":"https://openalex.org/I52099693","display_name":"University of York","ror":"https://ror.org/04m01e293","country_code":"GB","type":"education","lineage":["https://openalex.org/I52099693"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jon Timmis","raw_affiliation_strings":["1 Edward Jenner Institute, Compton, Newbury, Berkshire, RG20 7NN, 2Department of Computing and Centre for BioMedical Informatics, University of Kent, Canterbury, Kent CT2 7NF and 3Departments of Computer Science and Electronics, University of York, Heslington, York YO10 5DD, UK"],"affiliations":[{"raw_affiliation_string":"1 Edward Jenner Institute, Compton, Newbury, Berkshire, RG20 7NN, 2Department of Computing and Centre for BioMedical Informatics, University of Kent, Canterbury, Kent CT2 7NF and 3Departments of Computer Science and Electronics, University of York, Heslington, York YO10 5DD, UK","institution_ids":["https://openalex.org/I4210153742","https://openalex.org/I20581793","https://openalex.org/I52099693"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052912254","display_name":"Darren R. Flower","orcid":"https://orcid.org/0000-0002-8542-7067"},"institutions":[{"id":"https://openalex.org/I52099693","display_name":"University of York","ror":"https://ror.org/04m01e293","country_code":"GB","type":"education","lineage":["https://openalex.org/I52099693"]},{"id":"https://openalex.org/I20581793","display_name":"University of Kent","ror":"https://ror.org/00xkeyj56","country_code":"GB","type":"education","lineage":["https://openalex.org/I20581793"]},{"id":"https://openalex.org/I4210153742","display_name":"Jenner Institute","ror":"https://ror.org/05kwhph67","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210153742"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Darren R. Flower","raw_affiliation_strings":["1 Edward Jenner Institute, Compton, Newbury, Berkshire, RG20 7NN, 2Department of Computing and Centre for BioMedical Informatics, University of Kent, Canterbury, Kent CT2 7NF and 3Departments of Computer Science and Electronics, University of York, Heslington, York YO10 5DD, UK"],"affiliations":[{"raw_affiliation_string":"1 Edward Jenner Institute, Compton, Newbury, Berkshire, RG20 7NN, 2Department of Computing and Centre for BioMedical Informatics, University of Kent, Canterbury, Kent CT2 7NF and 3Departments of Computer Science and Electronics, University of York, Heslington, York YO10 5DD, UK","institution_ids":["https://openalex.org/I4210153742","https://openalex.org/I20581793","https://openalex.org/I52099693"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5103363322"],"corresponding_institution_ids":["https://openalex.org/I20581793","https://openalex.org/I4210153742","https://openalex.org/I52099693"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":1.6597,"has_fulltext":true,"cited_by_count":72,"citation_normalized_percentile":{"value":0.83478473,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"24","issue":"18","first_page":"1980","last_page":"1986"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.665734052658081},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.5920625925064087},{"id":"https://openalex.org/keywords/alphabet","display_name":"Alphabet","score":0.5325913429260254},{"id":"https://openalex.org/keywords/representation","display_name":"Representation (politics)","score":0.5316513180732727},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.49777892231941223},{"id":"https://openalex.org/keywords/amino-acid-residue","display_name":"Amino acid residue","score":0.45643508434295654},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4087281823158264},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3650576174259186},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1547754406929016},{"id":"https://openalex.org/keywords/peptide-sequence","display_name":"Peptide sequence","score":0.1490311622619629},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.07991689443588257}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.665734052658081},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5920625925064087},{"id":"https://openalex.org/C112876837","wikidata":"https://www.wikidata.org/wiki/Q837518","display_name":"Alphabet","level":2,"score":0.5325913429260254},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.5316513180732727},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.49777892231941223},{"id":"https://openalex.org/C2994376932","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Amino acid residue","level":4,"score":0.45643508434295654},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4087281823158264},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3650576174259186},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1547754406929016},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.1490311622619629},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07991689443588257},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btn382","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn382","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/24/18/1980/476828/btn382.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:18676973","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18676973","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:kar.kent.ac.uk:24049","is_oa":false,"landing_page_url":"https://kar.kent.ac.uk/24049/","pdf_url":null,"source":{"id":"https://openalex.org/S4377196264","display_name":"Kent Academic Repository (University of Kent)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I20581793","host_organization_name":"University of Kent","host_organization_lineage":["https://openalex.org/I20581793"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btn382","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn382","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/24/18/1980/476828/btn382.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Quality Education","id":"https://metadata.un.org/sdg/4","score":0.6899999976158142}],"awards":[{"id":"https://openalex.org/G5403949048","display_name":"A Synergistic Integration of Natural and Artificial Immunology for the Prediction of Hierarchical Protein Functions","funder_award_id":"EP/D501377/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G5862820587","display_name":null,"funder_award_id":"EP/D501377/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320320666","display_name":"University of Kent","ror":"https://ror.org/00xkeyj56"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2139237500.pdf","grobid_xml":"https://content.openalex.org/works/W2139237500.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W130232500","https://openalex.org/W192749064","https://openalex.org/W1525048611","https://openalex.org/W1530641120","https://openalex.org/W1570448133","https://openalex.org/W1974664442","https://openalex.org/W1975670646","https://openalex.org/W1982481323","https://openalex.org/W1986357706","https://openalex.org/W2001316303","https://openalex.org/W2005120335","https://openalex.org/W2005462790","https://openalex.org/W2005604222","https://openalex.org/W2014332260","https://openalex.org/W2022368654","https://openalex.org/W2023994620","https://openalex.org/W2042209813","https://openalex.org/W2051869681","https://openalex.org/W2052151503","https://openalex.org/W2052376307","https://openalex.org/W2076976482","https://openalex.org/W2090669407","https://openalex.org/W2091568186","https://openalex.org/W2095775529","https://openalex.org/W2100124066","https://openalex.org/W2103031848","https://openalex.org/W2108398740","https://openalex.org/W2109014958","https://openalex.org/W2121847038","https://openalex.org/W2124073224","https://openalex.org/W2125652418","https://openalex.org/W2130783152","https://openalex.org/W2139774535","https://openalex.org/W2139865428","https://openalex.org/W2157516796","https://openalex.org/W2164934768","https://openalex.org/W2601913882","https://openalex.org/W4242830269","https://openalex.org/W4285719527","https://openalex.org/W6638291719"],"related_works":["https://openalex.org/W2074481494","https://openalex.org/W2808006995","https://openalex.org/W4250156143","https://openalex.org/W4247156967","https://openalex.org/W582626623","https://openalex.org/W4240940369","https://openalex.org/W4298850403","https://openalex.org/W2808496111","https://openalex.org/W4233641337","https://openalex.org/W1993257543"],"abstract_inverted_index":{"Within":[0],"the":[1,19,34],"context":[2],"of":[3,40,46,66],"G-protein":[4],"coupled":[5],"receptor":[6],"(GPCR)":[7],"classification,":[8],"an":[9,68],"optimization":[10],"algorithm":[11,30,53,71],"was":[12,15,31],"developed,":[13],"which":[14],"able":[16],"to":[17,25,58,61],"identify":[18],"most":[20],"efficient":[21],"grouping":[22],"when":[23],"used":[24],"generate":[26,62],"local":[27,63],"descriptors.":[28],"The":[29],"inspired":[32],"by":[33,51],"relatively":[35],"new":[36],"computational":[37],"intelligence":[38],"paradigm":[39],"artificial":[41],"immune":[42],"systems.":[43],"A":[44],"number":[45],"amino":[47],"acid":[48],"groupings":[49],"produced":[50],"this":[52],"were":[54],"evaluated":[55],"with":[56],"respect":[57],"their":[59],"ability":[60],"descriptors":[64],"capable":[65],"providing":[67],"accurate":[69],"classification":[70],"for":[72],"GPCRs.":[73]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":3}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}