{"id":"https://openalex.org/W2170241526","doi":"https://doi.org/10.1093/bioinformatics/btn296","title":"Functional coherence in domain interaction networks","display_name":"Functional coherence in domain interaction networks","publication_year":2008,"publication_date":"2008-08-09","ids":{"openalex":"https://openalex.org/W2170241526","doi":"https://doi.org/10.1093/bioinformatics/btn296","mag":"2170241526","pmid":"https://pubmed.ncbi.nlm.nih.gov/18689835"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btn296","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn296","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/24/16/i28/517624/btn296.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/24/16/i28/517624/btn296.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069688744","display_name":"Jayesh Pandey","orcid":"https://orcid.org/0000-0003-4009-9677"},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California, San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]},{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jayesh Pandey","raw_affiliation_strings":["1 Department of Computer Science, Purdue University, West Lafayette, IN, USA, 2Department of Electrical Engineering & Computer Science, Case Western Reserve University, Cleveland, OH, USA and 3Department of Biomedical Engineering, University of California, San Diego, USA, CA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Purdue University, West Lafayette, IN, USA, 2Department of Electrical Engineering & Computer Science, Case Western Reserve University, Cleveland, OH, USA and 3Department of Biomedical Engineering, University of California, San Diego, USA, CA","institution_ids":["https://openalex.org/I219193219","https://openalex.org/I36258959","https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035558591","display_name":"Mehmet Koyut\u00fcrk","orcid":"https://orcid.org/0000-0002-3434-5512"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]},{"id":"https://openalex.org/I36258959","display_name":"University of California, San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mehmet Koyut\u00fcrk","raw_affiliation_strings":["1 Department of Computer Science, Purdue University, West Lafayette, IN, USA, 2Department of Electrical Engineering & Computer Science, Case Western Reserve University, Cleveland, OH, USA and 3Department of Biomedical Engineering, University of California, San Diego, USA, CA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Purdue University, West Lafayette, IN, USA, 2Department of Electrical Engineering & Computer Science, Case Western Reserve University, Cleveland, OH, USA and 3Department of Biomedical Engineering, University of California, San Diego, USA, CA","institution_ids":["https://openalex.org/I219193219","https://openalex.org/I36258959","https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063396453","display_name":"Shankar Subramaniam","orcid":"https://orcid.org/0000-0002-8059-4659"},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]},{"id":"https://openalex.org/I36258959","display_name":"University of California, San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shankar Subramaniam","raw_affiliation_strings":["1 Department of Computer Science, Purdue University, West Lafayette, IN, USA, 2Department of Electrical Engineering & Computer Science, Case Western Reserve University, Cleveland, OH, USA and 3Department of Biomedical Engineering, University of California, San Diego, USA, CA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Purdue University, West Lafayette, IN, USA, 2Department of Electrical Engineering & Computer Science, Case Western Reserve University, Cleveland, OH, USA and 3Department of Biomedical Engineering, University of California, San Diego, USA, CA","institution_ids":["https://openalex.org/I219193219","https://openalex.org/I36258959","https://openalex.org/I58956616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019202832","display_name":"Ananth Grama","orcid":"https://orcid.org/0000-0002-9378-9244"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]},{"id":"https://openalex.org/I36258959","display_name":"University of California, San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ananth Grama","raw_affiliation_strings":["1 Department of Computer Science, Purdue University, West Lafayette, IN, USA, 2Department of Electrical Engineering & Computer Science, Case Western Reserve University, Cleveland, OH, USA and 3Department of Biomedical Engineering, University of California, San Diego, USA, CA"],"affiliations":[{"raw_affiliation_string":"1 Department of Computer Science, Purdue University, West Lafayette, IN, USA, 2Department of Electrical Engineering & Computer Science, Case Western Reserve University, Cleveland, OH, USA and 3Department of Biomedical Engineering, University of California, San Diego, USA, CA","institution_ids":["https://openalex.org/I219193219","https://openalex.org/I36258959","https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5069688744"],"corresponding_institution_ids":["https://openalex.org/I219193219","https://openalex.org/I36258959","https://openalex.org/I58956616"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":2.5587,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.89871073,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"24","issue":"16","first_page":"i28","last_page":"i34"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9914000034332275,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7133625745773315},{"id":"https://openalex.org/keywords/coherence","display_name":"Coherence (philosophical gambling strategy)","score":0.6490137577056885},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.557450532913208},{"id":"https://openalex.org/keywords/domain","display_name":"Domain (mathematical analysis)","score":0.5542025566101074},{"id":"https://openalex.org/keywords/measure","display_name":"Measure (data warehouse)","score":0.47341591119766235},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4524752199649811},{"id":"https://openalex.org/keywords/similarity-measure","display_name":"Similarity measure","score":0.41325676441192627},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.4028116464614868},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.37605124711990356},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.37397876381874084},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.16025587916374207}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7133625745773315},{"id":"https://openalex.org/C2781181686","wikidata":"https://www.wikidata.org/wiki/Q4226068","display_name":"Coherence (philosophical gambling strategy)","level":2,"score":0.6490137577056885},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.557450532913208},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.5542025566101074},{"id":"https://openalex.org/C2780009758","wikidata":"https://www.wikidata.org/wiki/Q6804172","display_name":"Measure (data warehouse)","level":2,"score":0.47341591119766235},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4524752199649811},{"id":"https://openalex.org/C2776517306","wikidata":"https://www.wikidata.org/wiki/Q29017317","display_name":"Similarity measure","level":2,"score":0.41325676441192627},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.4028116464614868},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.37605124711990356},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.37397876381874084},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.16025587916374207},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btn296","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn296","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/24/16/i28/517624/btn296.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:18689835","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18689835","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.585.3886","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.585.3886","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://bioinformatics.oxfordjournals.org/content/24/16/i28.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btn296","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btn296","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/24/16/i28/517624/btn296.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2170241526.pdf","grobid_xml":"https://content.openalex.org/works/W2170241526.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1493403933","https://openalex.org/W1647729745","https://openalex.org/W1843018858","https://openalex.org/W1958621998","https://openalex.org/W1974139890","https://openalex.org/W1974640858","https://openalex.org/W1978920477","https://openalex.org/W1986512768","https://openalex.org/W2012852001","https://openalex.org/W2045131140","https://openalex.org/W2046618236","https://openalex.org/W2099047355","https://openalex.org/W2100935296","https://openalex.org/W2103017472","https://openalex.org/W2117035344","https://openalex.org/W2117805756","https://openalex.org/W2123501554","https://openalex.org/W2126225210","https://openalex.org/W2127563440","https://openalex.org/W2141885858","https://openalex.org/W2152495216","https://openalex.org/W2160521949","https://openalex.org/W2166468869","https://openalex.org/W2917431650","https://openalex.org/W2950225692","https://openalex.org/W4210400672","https://openalex.org/W6629392126","https://openalex.org/W6636975626","https://openalex.org/W6675339850","https://openalex.org/W6677712588"],"related_works":["https://openalex.org/W2319693127","https://openalex.org/W2163064108","https://openalex.org/W2474567666","https://openalex.org/W2327130486","https://openalex.org/W2072263576","https://openalex.org/W2790658443","https://openalex.org/W2767257176","https://openalex.org/W2915154372","https://openalex.org/W1940044583","https://openalex.org/W2056226831"],"abstract_inverted_index":{"We":[0,19,47],"investigate":[1],"the":[2,6,64,108],"problem":[3],"of":[4,9,23,26,66],"assessing":[5],"functional":[7,27,52,59,67,74,111,137,157],"coherence":[8],"two":[10],"biomolecules":[11],"(or":[12],"segments":[13],"thereof)":[14],"in":[15,76,118,143,147],"a":[16,49,77,119],"formal":[17],"framework.":[18],"establish":[20],"essential":[21],"attributes":[22,68],"admissible":[24],"measures":[25,34,131],"coherence,":[28],"and":[29,80,90,98,113,132,136,150],"demonstrate":[30],"that":[31,55,151],"existing,":[32],"well-accepted":[33],"are":[35,139],"ill-suited":[36],"to":[37,72,129,161],"comparative":[38],"analyses":[39],"involving":[40],"different":[41,103],"entities":[42],"(i.e.":[43],"domains":[44],"versus":[45],"proteins).":[46],"propose":[48],"statistically":[50,78],"motivated":[51],"similarity":[53,75,112,138],"measure":[54],"takes":[56],"into":[57],"account":[58],"specificity":[60],"as":[61,63,94,96,159],"well":[62,95],"distribution":[65],"across":[69],"entity":[70],"groups":[71],"assess":[73],"meaningful":[79],"biologically":[81],"interpretable":[82],"manner.":[83],"Results":[84],"on":[85],"diverse":[86],"data,":[87],"including":[88],"high-throughput":[89],"computationally":[91,99,162],"predicted":[92],"PPIs,":[93],"structural":[97],"inferred":[100,163],"DDIs":[101,154],"for":[102],"organisms":[104],"show":[105],"that:":[106],"(i)":[107],"relationship":[109],"between":[110],"network":[114,134],"proximity":[115,135],"is":[116],"captured":[117],"much":[120],"more":[121,141],"(biologically)":[122],"intuitive":[123],"manner":[124],"by":[125],"our":[126],"measure,":[127],"compared":[128,160],"existing":[130],"(ii)":[133],"significantly":[140],"correlated":[142],"DDI":[144],"networks":[145],"than":[146],"PPI":[148],"networks,":[149],"structurally":[152],"determined":[153],"provide":[155],"better":[156],"relevance":[158],"DDIs.":[164]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":5}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}