{"id":"https://openalex.org/W2139685618","doi":"https://doi.org/10.1093/bioinformatics/btm588","title":"TOM: enhancement and extension of a tool suite for <i>in silico</i> approaches to multigenic hereditary disorders","display_name":"TOM: enhancement and extension of a tool suite for <i>in silico</i> approaches to multigenic hereditary disorders","publication_year":2007,"publication_date":"2007-11-29","ids":{"openalex":"https://openalex.org/W2139685618","doi":"https://doi.org/10.1093/bioinformatics/btm588","mag":"2139685618","pmid":"https://pubmed.ncbi.nlm.nih.gov/18048394"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btm588","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btm588","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/24/3/428/701551/btm588.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/24/3/428/701551/btm588.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017574404","display_name":"D. Masotti","orcid":null},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Daniele Masotti","raw_affiliation_strings":["1 Dipartimento di Elettronica, Informatica e Sistemistica (DEIS), University of Bologna, Viale Risorgimento 2, 40136 Bologna, 2Functional Genomics Laboratory and Telethon Facility \u2013 DAMA Data Mining for Analysis of DNA Microarrays, Dipartimento di Morfologia ed Embriologia, Via Fossato di Mortara 64b, 44100 Ferrara and 3Unit\u00e1 di Genetica Medica, Policlinico S. Orsola, via Massarenti 9,40138 Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Dipartimento di Elettronica, Informatica e Sistemistica (DEIS), University of Bologna, Viale Risorgimento 2, 40136 Bologna, 2Functional Genomics Laboratory and Telethon Facility \u2013 DAMA Data Mining for Analysis of DNA Microarrays, Dipartimento di Morfologia ed Embriologia, Via Fossato di Mortara 64b, 44100 Ferrara and 3Unit\u00e1 di Genetica Medica, Policlinico S. Orsola, via Massarenti 9,40138 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081542076","display_name":"Christine Nardini","orcid":"https://orcid.org/0000-0001-7601-321X"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Christine Nardini","raw_affiliation_strings":["1 Dipartimento di Elettronica, Informatica e Sistemistica (DEIS), University of Bologna, Viale Risorgimento 2, 40136 Bologna, 2Functional Genomics Laboratory and Telethon Facility \u2013 DAMA Data Mining for Analysis of DNA Microarrays, Dipartimento di Morfologia ed Embriologia, Via Fossato di Mortara 64b, 44100 Ferrara and 3Unit\u00e1 di Genetica Medica, Policlinico S. Orsola, via Massarenti 9,40138 Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Dipartimento di Elettronica, Informatica e Sistemistica (DEIS), University of Bologna, Viale Risorgimento 2, 40136 Bologna, 2Functional Genomics Laboratory and Telethon Facility \u2013 DAMA Data Mining for Analysis of DNA Microarrays, Dipartimento di Morfologia ed Embriologia, Via Fossato di Mortara 64b, 44100 Ferrara and 3Unit\u00e1 di Genetica Medica, Policlinico S. Orsola, via Massarenti 9,40138 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006023626","display_name":"Simona Rossi","orcid":"https://orcid.org/0000-0001-5038-0767"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Simona Rossi","raw_affiliation_strings":["1 Dipartimento di Elettronica, Informatica e Sistemistica (DEIS), University of Bologna, Viale Risorgimento 2, 40136 Bologna, 2Functional Genomics Laboratory and Telethon Facility \u2013 DAMA Data Mining for Analysis of DNA Microarrays, Dipartimento di Morfologia ed Embriologia, Via Fossato di Mortara 64b, 44100 Ferrara and 3Unit\u00e1 di Genetica Medica, Policlinico S. Orsola, via Massarenti 9,40138 Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Dipartimento di Elettronica, Informatica e Sistemistica (DEIS), University of Bologna, Viale Risorgimento 2, 40136 Bologna, 2Functional Genomics Laboratory and Telethon Facility \u2013 DAMA Data Mining for Analysis of DNA Microarrays, Dipartimento di Morfologia ed Embriologia, Via Fossato di Mortara 64b, 44100 Ferrara and 3Unit\u00e1 di Genetica Medica, Policlinico S. Orsola, via Massarenti 9,40138 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067024369","display_name":"Elena Bonora","orcid":"https://orcid.org/0000-0001-6132-7734"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elena Bonora","raw_affiliation_strings":["1 Dipartimento di Elettronica, Informatica e Sistemistica (DEIS), University of Bologna, Viale Risorgimento 2, 40136 Bologna, 2Functional Genomics Laboratory and Telethon Facility \u2013 DAMA Data Mining for Analysis of DNA Microarrays, Dipartimento di Morfologia ed Embriologia, Via Fossato di Mortara 64b, 44100 Ferrara and 3Unit\u00e1 di Genetica Medica, Policlinico S. Orsola, via Massarenti 9,40138 Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Dipartimento di Elettronica, Informatica e Sistemistica (DEIS), University of Bologna, Viale Risorgimento 2, 40136 Bologna, 2Functional Genomics Laboratory and Telethon Facility \u2013 DAMA Data Mining for Analysis of DNA Microarrays, Dipartimento di Morfologia ed Embriologia, Via Fossato di Mortara 64b, 44100 Ferrara and 3Unit\u00e1 di Genetica Medica, Policlinico S. Orsola, via Massarenti 9,40138 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105411647","display_name":"G. Cara Romeo","orcid":"https://orcid.org/0000-0002-3242-4276"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giovanni Romeo","raw_affiliation_strings":["1 Dipartimento di Elettronica, Informatica e Sistemistica (DEIS), University of Bologna, Viale Risorgimento 2, 40136 Bologna, 2Functional Genomics Laboratory and Telethon Facility \u2013 DAMA Data Mining for Analysis of DNA Microarrays, Dipartimento di Morfologia ed Embriologia, Via Fossato di Mortara 64b, 44100 Ferrara and 3Unit\u00e1 di Genetica Medica, Policlinico S. Orsola, via Massarenti 9,40138 Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Dipartimento di Elettronica, Informatica e Sistemistica (DEIS), University of Bologna, Viale Risorgimento 2, 40136 Bologna, 2Functional Genomics Laboratory and Telethon Facility \u2013 DAMA Data Mining for Analysis of DNA Microarrays, Dipartimento di Morfologia ed Embriologia, Via Fossato di Mortara 64b, 44100 Ferrara and 3Unit\u00e1 di Genetica Medica, Policlinico S. Orsola, via Massarenti 9,40138 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036085776","display_name":"Stefano Volinia","orcid":"https://orcid.org/0000-0003-0910-3893"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Stefano Volinia","raw_affiliation_strings":["1 Dipartimento di Elettronica, Informatica e Sistemistica (DEIS), University of Bologna, Viale Risorgimento 2, 40136 Bologna, 2Functional Genomics Laboratory and Telethon Facility \u2013 DAMA Data Mining for Analysis of DNA Microarrays, Dipartimento di Morfologia ed Embriologia, Via Fossato di Mortara 64b, 44100 Ferrara and 3Unit\u00e1 di Genetica Medica, Policlinico S. Orsola, via Massarenti 9,40138 Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Dipartimento di Elettronica, Informatica e Sistemistica (DEIS), University of Bologna, Viale Risorgimento 2, 40136 Bologna, 2Functional Genomics Laboratory and Telethon Facility \u2013 DAMA Data Mining for Analysis of DNA Microarrays, Dipartimento di Morfologia ed Embriologia, Via Fossato di Mortara 64b, 44100 Ferrara and 3Unit\u00e1 di Genetica Medica, Policlinico S. Orsola, via Massarenti 9,40138 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043408422","display_name":"Luca Benini","orcid":"https://orcid.org/0000-0001-8068-3806"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luca Benini","raw_affiliation_strings":["1 Dipartimento di Elettronica, Informatica e Sistemistica (DEIS), University of Bologna, Viale Risorgimento 2, 40136 Bologna, 2Functional Genomics Laboratory and Telethon Facility \u2013 DAMA Data Mining for Analysis of DNA Microarrays, Dipartimento di Morfologia ed Embriologia, Via Fossato di Mortara 64b, 44100 Ferrara and 3Unit\u00e1 di Genetica Medica, Policlinico S. Orsola, via Massarenti 9,40138 Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Dipartimento di Elettronica, Informatica e Sistemistica (DEIS), University of Bologna, Viale Risorgimento 2, 40136 Bologna, 2Functional Genomics Laboratory and Telethon Facility \u2013 DAMA Data Mining for Analysis of DNA Microarrays, Dipartimento di Morfologia ed Embriologia, Via Fossato di Mortara 64b, 44100 Ferrara and 3Unit\u00e1 di Genetica Medica, Policlinico S. Orsola, via Massarenti 9,40138 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5017574404"],"corresponding_institution_ids":["https://openalex.org/I9360294"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":1.6371,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.85288572,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"24","issue":"3","first_page":"428","last_page":"429"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.946399986743927,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.946399986743927,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.016499999910593033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/in-silico","display_name":"In silico","score":0.6969144344329834},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.6336648464202881},{"id":"https://openalex.org/keywords/suite","display_name":"Suite","score":0.5928597450256348},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5808780193328857},{"id":"https://openalex.org/keywords/hereditary-diseases","display_name":"Hereditary Diseases","score":0.41628628969192505},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3825500011444092},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3694692552089691},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.35660094022750854},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3319776654243469},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.26697513461112976},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1736074686050415},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.15631920099258423},{"id":"https://openalex.org/keywords/geography","display_name":"Geography","score":0.07971727848052979}],"concepts":[{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.6969144344329834},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6336648464202881},{"id":"https://openalex.org/C79581498","wikidata":"https://www.wikidata.org/wiki/Q1367530","display_name":"Suite","level":2,"score":0.5928597450256348},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5808780193328857},{"id":"https://openalex.org/C2910788575","wikidata":"https://www.wikidata.org/wiki/Q200779","display_name":"Hereditary Diseases","level":3,"score":0.41628628969192505},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3825500011444092},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3694692552089691},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.35660094022750854},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3319776654243469},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26697513461112976},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1736074686050415},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15631920099258423},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.07971727848052979},{"id":"https://openalex.org/C166957645","wikidata":"https://www.wikidata.org/wiki/Q23498","display_name":"Archaeology","level":1,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015810","descriptor_name":"Linkage Disequilibrium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015810","descriptor_name":"Linkage Disequilibrium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015810","descriptor_name":"Linkage Disequilibrium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015810","descriptor_name":"Linkage Disequilibrium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030342","descriptor_name":"Genetic Diseases, Inborn","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D030342","descriptor_name":"Genetic Diseases, Inborn","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D030342","descriptor_name":"Genetic Diseases, Inborn","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D030342","descriptor_name":"Genetic Diseases, Inborn","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1093/bioinformatics/btm588","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btm588","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/24/3/428/701551/btm588.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:18048394","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18048394","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:cris.unibo.it:11585/51685","is_oa":false,"landing_page_url":"http://hdl.handle.net/11585/51685","pdf_url":null,"source":{"id":"https://openalex.org/S4306402579","display_name":"Archivio istituzionale della ricerca (Alma Mater Studiorum Universit\u00e0 di Bologna)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210117483","host_organization_name":"Istituto di Ematologia di Bologna","host_organization_lineage":["https://openalex.org/I4210117483"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.unife.it:11392/525671","is_oa":false,"landing_page_url":"http://hdl.handle.net/11392/525671","pdf_url":null,"source":{"id":"https://openalex.org/S4306400369","display_name":"Institutional Research Information System University of Ferrara (University of Ferrara)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I201324441","host_organization_name":"University of Ferrara","host_organization_lineage":["https://openalex.org/I201324441"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:zenodo.org:100679","is_oa":true,"landing_page_url":"https://www.openaccessrepository.it/record/100679","pdf_url":null,"source":{"id":"https://openalex.org/S4306402478","display_name":"INFM-OAR (INFN Catania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210116497","host_organization_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Catania","host_organization_lineage":["https://openalex.org/I4210116497"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btm588","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btm588","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/24/3/428/701551/btm588.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2139685618.pdf"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1597538863","https://openalex.org/W1980548655","https://openalex.org/W1994583626","https://openalex.org/W1999649023","https://openalex.org/W2020541351","https://openalex.org/W2032679606","https://openalex.org/W2084481314","https://openalex.org/W2106323366","https://openalex.org/W2119943416","https://openalex.org/W2135230352","https://openalex.org/W2135859936","https://openalex.org/W2146851632","https://openalex.org/W2159482845","https://openalex.org/W2797884775","https://openalex.org/W4246066782","https://openalex.org/W4294216483","https://openalex.org/W6681677027"],"related_works":["https://openalex.org/W2584152819","https://openalex.org/W2213189664","https://openalex.org/W2321768478","https://openalex.org/W4236496714","https://openalex.org/W1970630803","https://openalex.org/W4206388388","https://openalex.org/W4205746148","https://openalex.org/W4249776205","https://openalex.org/W4293076875","https://openalex.org/W4205568524"],"abstract_inverted_index":{"Abstract":[0],"Summary:":[1],"The":[2,15],"study":[3,89],"of":[4,13,18,29,37,42,65,84,90,117],"complex":[5,91],"hereditary":[6,69,92],"diseases":[7],"is":[8,97],"a":[9,23],"very":[10],"challenging":[11],"area":[12,34],"research.":[14],"expanding":[16],"set":[17],"in":[19,32,87,113],"silico":[20],"approaches":[21,46],"offers":[22],"flourishing":[24],"ground":[25],"for":[26,68,81],"the":[27,63,82,88,114,118],"acceleration":[28],"meaningful":[30],"findings":[31],"this":[33,72],"by":[35],"exploitation":[36],"rich":[38],"and":[39,53,59,76,108],"diverse":[40],"sources":[41],"omic":[43],"data.":[44],"These":[45],"are":[47,111],"cheap,":[48],"flexible,":[49],"extensible,":[50],"often":[51],"complementary":[52],"can":[54],"continuously":[55],"integrate":[56],"new":[57],"information":[58],"tests":[60],"to":[61],"improve":[62],"selection":[64],"genes":[66,86],"responsible":[67],"diseases.":[70,93],"Following":[71],"principle,":[73],"we":[74],"improved":[75],"extended":[77],"our":[78],"web-service":[79],"TOM":[80],"identification":[83],"candidate":[85],"Availability:":[94],"Our":[95],"tool":[96],"freely":[98],"available":[99,112],"online":[100],"at":[101],"http://www.micrel.deis.unibo.it/~tom/.":[102],"Contact:":[103],"daniele.masotti@unibo.it":[104],"Supplementary":[105],"information:":[106],"Manuals":[107],"sample":[109],"data":[110],"Help":[115],"section":[116],"tool's":[119],"web":[120],"page.":[121]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-06-23T06:36:01.041984","created_date":"2016-06-24T00:00:00"}