{"id":"https://openalex.org/W2057473493","doi":"https://doi.org/10.1093/bioinformatics/btm522","title":"Detecting high-order interactions of single nucleotide polymorphisms using genetic programming","display_name":"Detecting high-order interactions of single nucleotide polymorphisms using genetic programming","publication_year":2007,"publication_date":"2007-11-15","ids":{"openalex":"https://openalex.org/W2057473493","doi":"https://doi.org/10.1093/bioinformatics/btm522","mag":"2057473493","pmid":"https://pubmed.ncbi.nlm.nih.gov/18006552"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btm522","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btm522","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/23/24/3280/49823932/bioinformatics_23_24_3280.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/23/24/3280/49823932/bioinformatics_23_24_3280.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046866023","display_name":"Robin Nunkesser","orcid":"https://orcid.org/0009-0000-1238-8987"},"institutions":[{"id":"https://openalex.org/I200332995","display_name":"TU Dortmund University","ror":"https://ror.org/01k97gp34","country_code":"DE","type":"education","lineage":["https://openalex.org/I200332995"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Robin Nunkesser","raw_affiliation_strings":["1 Collaborative Research Center 475, 2Department of Computer Science and 3Department of Statistics, University of Dortmund, Dortmund, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Collaborative Research Center 475, 2Department of Computer Science and 3Department of Statistics, University of Dortmund, Dortmund, Germany","institution_ids":["https://openalex.org/I200332995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003618837","display_name":"Thorsten Bernholt","orcid":null},"institutions":[{"id":"https://openalex.org/I200332995","display_name":"TU Dortmund University","ror":"https://ror.org/01k97gp34","country_code":"DE","type":"education","lineage":["https://openalex.org/I200332995"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thorsten Bernholt","raw_affiliation_strings":["1 Collaborative Research Center 475, 2Department of Computer Science and 3Department of Statistics, University of Dortmund, Dortmund, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Collaborative Research Center 475, 2Department of Computer Science and 3Department of Statistics, University of Dortmund, Dortmund, Germany","institution_ids":["https://openalex.org/I200332995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037974033","display_name":"Holger Schwender","orcid":"https://orcid.org/0000-0002-2858-6715"},"institutions":[{"id":"https://openalex.org/I200332995","display_name":"TU Dortmund University","ror":"https://ror.org/01k97gp34","country_code":"DE","type":"education","lineage":["https://openalex.org/I200332995"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Holger Schwender","raw_affiliation_strings":["1 Collaborative Research Center 475, 2Department of Computer Science and 3Department of Statistics, University of Dortmund, Dortmund, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Collaborative Research Center 475, 2Department of Computer Science and 3Department of Statistics, University of Dortmund, Dortmund, Germany","institution_ids":["https://openalex.org/I200332995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063815245","display_name":"Katja Ickstadt","orcid":"https://orcid.org/0000-0001-5157-2496"},"institutions":[{"id":"https://openalex.org/I200332995","display_name":"TU Dortmund University","ror":"https://ror.org/01k97gp34","country_code":"DE","type":"education","lineage":["https://openalex.org/I200332995"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Katja Ickstadt","raw_affiliation_strings":["1 Collaborative Research Center 475, 2Department of Computer Science and 3Department of Statistics, University of Dortmund, Dortmund, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Collaborative Research Center 475, 2Department of Computer Science and 3Department of Statistics, University of Dortmund, Dortmund, Germany","institution_ids":["https://openalex.org/I200332995"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075262791","display_name":"Ingo Wegener","orcid":null},"institutions":[{"id":"https://openalex.org/I200332995","display_name":"TU Dortmund University","ror":"https://ror.org/01k97gp34","country_code":"DE","type":"education","lineage":["https://openalex.org/I200332995"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ingo Wegener","raw_affiliation_strings":["1 Collaborative Research Center 475, 2Department of Computer Science and 3Department of Statistics, University of Dortmund, Dortmund, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Collaborative Research Center 475, 2Department of Computer Science and 3Department of Statistics, University of Dortmund, Dortmund, Germany","institution_ids":["https://openalex.org/I200332995"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5046866023"],"corresponding_institution_ids":["https://openalex.org/I200332995"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":3.7788,"has_fulltext":false,"cited_by_count":67,"citation_normalized_percentile":{"value":0.93927276,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"23","issue":"24","first_page":"3280","last_page":"3288"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.8907999992370605,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.8907999992370605,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.023600000888109207,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.012400000356137753,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.763093113899231},{"id":"https://openalex.org/keywords/categorical-variable","display_name":"Categorical variable","score":0.6362156271934509},{"id":"https://openalex.org/keywords/international-hapmap-project","display_name":"International HapMap Project","score":0.6181615591049194},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.5401008129119873},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.5089254379272461},{"id":"https://openalex.org/keywords/genetic-association","display_name":"Genetic association","score":0.5036823153495789},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.47670596837997437},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.45072224736213684},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4385717511177063},{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"Genome-wide association study","score":0.4370940923690796},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.43222275376319885},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.4102875590324402},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3974301517009735},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.20587828755378723},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.1445402204990387}],"concepts":[{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.763093113899231},{"id":"https://openalex.org/C5274069","wikidata":"https://www.wikidata.org/wiki/Q2285707","display_name":"Categorical variable","level":2,"score":0.6362156271934509},{"id":"https://openalex.org/C177580304","wikidata":"https://www.wikidata.org/wiki/Q1147298","display_name":"International HapMap Project","level":5,"score":0.6181615591049194},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.5401008129119873},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.5089254379272461},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.5036823153495789},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.47670596837997437},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45072224736213684},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4385717511177063},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.4370940923690796},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.43222275376319885},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.4102875590324402},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3974301517009735},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.20587828755378723},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1445402204990387},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004252","descriptor_name":"DNA Mutational Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004252","descriptor_name":"DNA Mutational Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004252","descriptor_name":"DNA Mutational Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011382","descriptor_name":"Programming, Linear","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011382","descriptor_name":"Programming, Linear","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011382","descriptor_name":"Programming, Linear","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btm522","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btm522","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/23/24/3280/49823932/bioinformatics_23_24_3280.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:18006552","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18006552","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:eldorado.tu-dortmund.de:2003/24441","is_oa":false,"landing_page_url":"http://hdl.handle.net/2003/24441","pdf_url":null,"source":{"id":"https://openalex.org/S4306400811","display_name":"Technische Universit\u00e4t Dortmund Eldorado (Technische Universit\u00e4t Dortmund)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210148506","host_organization_name":"Erich-Brost-Institut","host_organization_lineage":["https://openalex.org/I4210148506"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"doc-type:report"},{"id":"doi:10.17877/de290r-14487","is_oa":true,"landing_page_url":"https://doi.org/10.17877/de290r-14487","pdf_url":null,"source":{"id":"https://openalex.org/S4306400811","display_name":"Technische Universit\u00e4t Dortmund Eldorado (Technische Universit\u00e4t Dortmund)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210148506","host_organization_name":"Erich-Brost-Institut","host_organization_lineage":["https://openalex.org/I4210148506"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"report"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btm522","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btm522","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/23/24/3280/49823932/bioinformatics_23_24_3280.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities","score":0.4399999976158142},{"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions","score":0.4399999976158142}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2057473493.pdf"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W1520361406","https://openalex.org/W1539593569","https://openalex.org/W1576818901","https://openalex.org/W1594031697","https://openalex.org/W1966315117","https://openalex.org/W1980175560","https://openalex.org/W2058401000","https://openalex.org/W2063318748","https://openalex.org/W2083878136","https://openalex.org/W2097364929","https://openalex.org/W2098979053","https://openalex.org/W2100604298","https://openalex.org/W2107659056","https://openalex.org/W2109353557","https://openalex.org/W2114740540","https://openalex.org/W2119415736","https://openalex.org/W2124132382","https://openalex.org/W2133298971","https://openalex.org/W2143865774","https://openalex.org/W2154572047","https://openalex.org/W2157795344","https://openalex.org/W2189135377","https://openalex.org/W2238053594","https://openalex.org/W2330820318","https://openalex.org/W2404945087","https://openalex.org/W2517346518","https://openalex.org/W2607589993","https://openalex.org/W2911964244","https://openalex.org/W2912934387","https://openalex.org/W3085162807","https://openalex.org/W3145128584","https://openalex.org/W4212883601","https://openalex.org/W4231211138","https://openalex.org/W4246219036","https://openalex.org/W4294107304","https://openalex.org/W6632374317","https://openalex.org/W6674625439","https://openalex.org/W6676079644","https://openalex.org/W6679910551"],"related_works":["https://openalex.org/W2508339930","https://openalex.org/W2027381516","https://openalex.org/W4321749096","https://openalex.org/W1971424770","https://openalex.org/W2111842731","https://openalex.org/W2066467839","https://openalex.org/W1989752273","https://openalex.org/W2500027009","https://openalex.org/W2133538147","https://openalex.org/W2374413564"],"abstract_inverted_index":{"MOTIVATION:":[0],"Not":[1],"individual":[2,88],"single":[3],"nucleotide":[4],"polymorphisms":[5],"(SNPs),":[6],"but":[7,149,229],"high-order":[8,43,130,181],"interactions":[9,55,91,131,182],"of":[10,25,29,41,65,68,92,108,129,132,183,196,213],"SNPs":[11,184],"are":[12,57,102,199],"assumed":[13],"to":[14,98,160,179,186,210,222,234],"be":[15,144,152,232,241],"responsible":[16],"for":[17,60,104,146,154,193],"complex":[18],"diseases":[19],"such":[20,35,135],"as":[21,136],"cancer.":[22],"Therefore,":[23],"one":[24],"the":[26,39,51,69,75,109,127,161,165,214],"major":[27],"goals":[28],"genetic":[30,120],"association":[31,169,223],"studies":[32,224],"concerned":[33,171],"with":[34,172],"genotype":[36,162],"data":[37,163,216],"is":[38,47,177,219],"identification":[40,128],"these":[42,54],"interactions.":[44],"This":[45,138],"search":[46],"additionally":[48],"impeded":[49],"by":[50,202],"fact":[52],"that":[53,101,125,198],"often":[56],"only":[58,86,143],"explanatory":[59,103],"a":[61,93,105,116,187,211],"relatively":[62],"small":[63],"subgroup":[64],"patients.":[66],"Most":[67],"feature":[70,147,204],"selection":[71,205],"methods":[72],"proposed":[73],"in":[74],"literature,":[76],"unfortunately,":[77],"fail":[78],"at":[79],"this":[80,112],"task,":[81],"since":[82],"they":[83],"can":[84,150,230,240],"either":[85],"identify":[87,180],"variables":[89,134],"or":[90,96],"low":[94],"order,":[95],"try":[97],"find":[99],"rules":[100],"high":[106],"percentage":[107],"observations.":[110],"In":[111,157],"article,":[113],"we":[114],"present":[115],"procedure":[117],"based":[118],"on":[119],"programming":[121],"and":[122],"multi-valued":[123],"logic":[124],"enables":[126],"categorical":[133],"SNPs.":[137],"method":[139],"called":[140],"GPAS":[141,176,218],"cannot":[142],"used":[145],"selection,":[148],"also":[151,231],"employed":[153,233],"discrimination.":[155],"RESULTS:":[156],"an":[158,168,208],"application":[159,209],"from":[164,243],"GENICA":[166],"study,":[167],"study":[170],"sporadic":[173],"breast":[174,190],"cancer,":[175],"able":[178],"leading":[185],"considerably":[188],"increased":[189],"cancer":[191],"risk":[192],"different":[194],"subsets":[195],"patients":[197],"not":[200,220],"found":[201],"other":[203],"methods.":[206],"As":[207],"subset":[212],"HapMap":[215],"shows,":[217],"restricted":[221],"comprising":[225],"several":[226],"10":[227],"SNPs,":[228],"analyze":[235],"whole-genome":[236],"data.":[237],"AVAILABILITY:":[238],"Software":[239],"downloaded":[242],"http://ls2-www.cs.uni-dortmund.de/~nunkesser/#Software":[244]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":8},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":9}],"updated_date":"2026-06-17T06:14:20.161405","created_date":"2025-10-10T00:00:00"}