{"id":"https://openalex.org/W2115677665","doi":"https://doi.org/10.1093/bioinformatics/btl663","title":"Genomic characterization of multiple clinical phenotypes of cancer using multivariate linear regression models","display_name":"Genomic characterization of multiple clinical phenotypes of cancer using multivariate linear regression models","publication_year":2007,"publication_date":"2007-01-18","ids":{"openalex":"https://openalex.org/W2115677665","doi":"https://doi.org/10.1093/bioinformatics/btl663","mag":"2115677665","pmid":"https://pubmed.ncbi.nlm.nih.gov/17237045"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btl663","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl663","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053378428","display_name":"Shigeyuki Matsui","orcid":"https://orcid.org/0000-0003-2983-1919"},"institutions":[{"id":"https://openalex.org/I64189623","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25","country_code":"JP","type":"education","lineage":["https://openalex.org/I64189623"]},{"id":"https://openalex.org/I4210150196","display_name":"Kyoto University Hospital","ror":"https://ror.org/04k6gr834","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210150196"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Shigeyuki Matsui","raw_affiliation_strings":["1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan","institution_ids":["https://openalex.org/I4210150196","https://openalex.org/I64189623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062506663","display_name":"Masaaki Ito","orcid":"https://orcid.org/0000-0002-1101-2707"},"institutions":[{"id":"https://openalex.org/I64189623","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25","country_code":"JP","type":"education","lineage":["https://openalex.org/I64189623"]},{"id":"https://openalex.org/I4210150196","display_name":"Kyoto University Hospital","ror":"https://ror.org/04k6gr834","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210150196"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaaki Ito","raw_affiliation_strings":["1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan","institution_ids":["https://openalex.org/I4210150196","https://openalex.org/I64189623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071455815","display_name":"Hiroyuki Nishiyama","orcid":"https://orcid.org/0000-0001-7423-596X"},"institutions":[{"id":"https://openalex.org/I64189623","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25","country_code":"JP","type":"education","lineage":["https://openalex.org/I64189623"]},{"id":"https://openalex.org/I4210150196","display_name":"Kyoto University Hospital","ror":"https://ror.org/04k6gr834","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210150196"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroyuki Nishiyama","raw_affiliation_strings":["1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan","institution_ids":["https://openalex.org/I4210150196","https://openalex.org/I64189623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077058201","display_name":"Hajime Uno","orcid":"https://orcid.org/0000-0003-0622-8471"},"institutions":[{"id":"https://openalex.org/I4210150196","display_name":"Kyoto University Hospital","ror":"https://ror.org/04k6gr834","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210150196"]},{"id":"https://openalex.org/I64189623","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25","country_code":"JP","type":"education","lineage":["https://openalex.org/I64189623"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hajime Uno","raw_affiliation_strings":["1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan","institution_ids":["https://openalex.org/I4210150196","https://openalex.org/I64189623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109927835","display_name":"Hirokazu Kotani","orcid":null},"institutions":[{"id":"https://openalex.org/I4210150196","display_name":"Kyoto University Hospital","ror":"https://ror.org/04k6gr834","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210150196"]},{"id":"https://openalex.org/I64189623","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25","country_code":"JP","type":"education","lineage":["https://openalex.org/I64189623"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hirokazu Kotani","raw_affiliation_strings":["1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan","institution_ids":["https://openalex.org/I4210150196","https://openalex.org/I64189623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028322085","display_name":"Jun Watanabe","orcid":"https://orcid.org/0000-0002-7187-3664"},"institutions":[{"id":"https://openalex.org/I64189623","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25","country_code":"JP","type":"education","lineage":["https://openalex.org/I64189623"]},{"id":"https://openalex.org/I4210150196","display_name":"Kyoto University Hospital","ror":"https://ror.org/04k6gr834","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210150196"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Jun Watanabe","raw_affiliation_strings":["1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan","institution_ids":["https://openalex.org/I4210150196","https://openalex.org/I64189623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012739492","display_name":"Parry Guilford","orcid":"https://orcid.org/0000-0002-7256-9576"},"institutions":[{"id":"https://openalex.org/I4210150196","display_name":"Kyoto University Hospital","ror":"https://ror.org/04k6gr834","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210150196"]},{"id":"https://openalex.org/I64189623","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25","country_code":"JP","type":"education","lineage":["https://openalex.org/I64189623"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Parry Guilford","raw_affiliation_strings":["1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan","institution_ids":["https://openalex.org/I4210150196","https://openalex.org/I64189623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011628467","display_name":"Anthony E. Reeve","orcid":"https://orcid.org/0000-0002-5906-4055"},"institutions":[{"id":"https://openalex.org/I4210150196","display_name":"Kyoto University Hospital","ror":"https://ror.org/04k6gr834","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210150196"]},{"id":"https://openalex.org/I64189623","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25","country_code":"JP","type":"education","lineage":["https://openalex.org/I64189623"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Anthony Reeve","raw_affiliation_strings":["1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan","institution_ids":["https://openalex.org/I4210150196","https://openalex.org/I64189623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044882193","display_name":"Masanori Fukushima","orcid":"https://orcid.org/0000-0001-8594-0066"},"institutions":[{"id":"https://openalex.org/I4210150196","display_name":"Kyoto University Hospital","ror":"https://ror.org/04k6gr834","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210150196"]},{"id":"https://openalex.org/I64189623","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25","country_code":"JP","type":"education","lineage":["https://openalex.org/I64189623"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masanori Fukushima","raw_affiliation_strings":["1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan","institution_ids":["https://openalex.org/I4210150196","https://openalex.org/I64189623"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083025134","display_name":"Osamu Ogawa","orcid":"https://orcid.org/0000-0003-3651-5455"},"institutions":[{"id":"https://openalex.org/I4210150196","display_name":"Kyoto University Hospital","ror":"https://ror.org/04k6gr834","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210150196"]},{"id":"https://openalex.org/I64189623","display_name":"Kitasato University","ror":"https://ror.org/00f2txz25","country_code":"JP","type":"education","lineage":["https://openalex.org/I64189623"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Osamu Ogawa","raw_affiliation_strings":["1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan"],"affiliations":[{"raw_affiliation_string":"1 Department of Pharmacoepidemiology, Graduate School of Public Health, Kyoto University, Kyotom, 2Translational Research Informatics Center, Foundation for Biomedical Research and Innovation, Kobe, 3Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, 4Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, 5Department of Pathology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 6Pacific Edge Biotechnology, University of Otago, Dunedin, 7Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand and 8Dvision of Clinical Trial Design and Management, Translational Research Center, Kyoto University Hospital, Kyoto, Japan","institution_ids":["https://openalex.org/I4210150196","https://openalex.org/I64189623"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5053378428"],"corresponding_institution_ids":["https://openalex.org/I4210150196","https://openalex.org/I64189623"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.6545,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.68366346,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"23","issue":"6","first_page":"732","last_page":"738"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.9941999912261963,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.6305702924728394},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6103448271751404},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.5828076004981995},{"id":"https://openalex.org/keywords/multivariate-statistics","display_name":"Multivariate statistics","score":0.5635843873023987},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5359201431274414},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4925585389137268},{"id":"https://openalex.org/keywords/statistic","display_name":"Statistic","score":0.4876388609409332},{"id":"https://openalex.org/keywords/gene-selection","display_name":"Gene selection","score":0.4751986265182495},{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.4275043308734894},{"id":"https://openalex.org/keywords/microarray","display_name":"Microarray","score":0.4116983711719513},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3609614372253418},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.336322546005249},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.31132811307907104},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.23013025522232056},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.16919460892677307},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.12075719237327576},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.10468003153800964}],"concepts":[{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.6305702924728394},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6103448271751404},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.5828076004981995},{"id":"https://openalex.org/C161584116","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate statistics","level":2,"score":0.5635843873023987},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5359201431274414},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4925585389137268},{"id":"https://openalex.org/C89128539","wikidata":"https://www.wikidata.org/wiki/Q1949963","display_name":"Statistic","level":2,"score":0.4876388609409332},{"id":"https://openalex.org/C2984324147","wikidata":"https://www.wikidata.org/wiki/Q3080021","display_name":"Gene selection","level":5,"score":0.4751986265182495},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.4275043308734894},{"id":"https://openalex.org/C186836561","wikidata":"https://www.wikidata.org/wiki/Q1931516","display_name":"Microarray","level":4,"score":0.4116983711719513},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3609614372253418},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.336322546005249},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.31132811307907104},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.23013025522232056},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.16919460892677307},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.12075719237327576},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.10468003153800964}],"mesh":[{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D015999","descriptor_name":"Multivariate Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015999","descriptor_name":"Multivariate Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015999","descriptor_name":"Multivariate Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btl663","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl663","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:17237045","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17237045","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W575683998","https://openalex.org/W1506069954","https://openalex.org/W1508505201","https://openalex.org/W1965138864","https://openalex.org/W1992706551","https://openalex.org/W2002810210","https://openalex.org/W2049849487","https://openalex.org/W2058815839","https://openalex.org/W2074089196","https://openalex.org/W2080040490","https://openalex.org/W2093017030","https://openalex.org/W2096758922","https://openalex.org/W2105381419","https://openalex.org/W2116815663","https://openalex.org/W2120446363","https://openalex.org/W2127568565","https://openalex.org/W2129438293","https://openalex.org/W2140554638","https://openalex.org/W2144227498","https://openalex.org/W2153766534","https://openalex.org/W2157640699","https://openalex.org/W2157795344","https://openalex.org/W2159602607","https://openalex.org/W2166791970","https://openalex.org/W2317866228","https://openalex.org/W2503732610","https://openalex.org/W2504908677","https://openalex.org/W2897129259","https://openalex.org/W4239901699","https://openalex.org/W4294107304","https://openalex.org/W6665272994","https://openalex.org/W6680815069","https://openalex.org/W6683305439","https://openalex.org/W6724627997","https://openalex.org/W6755923013"],"related_works":["https://openalex.org/W2796636403","https://openalex.org/W2015700328","https://openalex.org/W2364565895","https://openalex.org/W2767847608","https://openalex.org/W2911678823","https://openalex.org/W2152648570","https://openalex.org/W2037892364","https://openalex.org/W2319154570","https://openalex.org/W3152114242","https://openalex.org/W3028764459"],"abstract_inverted_index":{"SAS":[0],"and":[1],"MATLAB":[2],"codes":[3],"are":[4],"available":[5],"from":[6],"author":[7],"upon":[8],"request.":[9]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}