{"id":"https://openalex.org/W2115233298","doi":"https://doi.org/10.1093/bioinformatics/btl500","title":"Large scale data mining approach for gene-specific standardization of microarray gene expression data","display_name":"Large scale data mining approach for gene-specific standardization of microarray gene expression data","publication_year":2006,"publication_date":"2006-10-10","ids":{"openalex":"https://openalex.org/W2115233298","doi":"https://doi.org/10.1093/bioinformatics/btl500","mag":"2115233298","pmid":"https://pubmed.ncbi.nlm.nih.gov/17032674"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btl500","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl500","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/23/2898/782600/btl500.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/22/23/2898/782600/btl500.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032052510","display_name":"Sukjoon Yoon","orcid":"https://orcid.org/0000-0001-7885-7117"},"institutions":[{"id":"https://openalex.org/I31766871","display_name":"Sookmyung Women's University","ror":"https://ror.org/00vvvt117","country_code":"KR","type":"education","lineage":["https://openalex.org/I31766871"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Sukjoon Yoon","raw_affiliation_strings":["Department of Biological Sciences, Sookmyung Women's University 1 \u00a0 1 \u00a0 \u00a0 Hyochangwongil 52, Youngsan-gu, Seoul, Republic of Korea, 140-742","Research Center for Women's Diseases (RCWD), Sookmyung Women's University 2 \u00a0 2 \u00a0 \u00a0 Hyochangwongil 52, Youngsan-gu, Seoul, Republic of Korea, 140-742"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Sookmyung Women's University 1 \u00a0 1 \u00a0 \u00a0 Hyochangwongil 52, Youngsan-gu, Seoul, Republic of Korea, 140-742","institution_ids":["https://openalex.org/I31766871"]},{"raw_affiliation_string":"Research Center for Women's Diseases (RCWD), Sookmyung Women's University 2 \u00a0 2 \u00a0 \u00a0 Hyochangwongil 52, Youngsan-gu, Seoul, Republic of Korea, 140-742","institution_ids":["https://openalex.org/I31766871"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051164633","display_name":"Young Yang","orcid":"https://orcid.org/0000-0003-4239-0804"},"institutions":[{"id":"https://openalex.org/I31766871","display_name":"Sookmyung Women's University","ror":"https://ror.org/00vvvt117","country_code":"KR","type":"education","lineage":["https://openalex.org/I31766871"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Young Yang","raw_affiliation_strings":["Department of Biological Sciences, Sookmyung Women's University 1 \u00a0 1 \u00a0 \u00a0 Hyochangwongil 52, Youngsan-gu, Seoul, Republic of Korea, 140-742","Research Center for Women's Diseases (RCWD), Sookmyung Women's University 2 \u00a0 2 \u00a0 \u00a0 Hyochangwongil 52, Youngsan-gu, Seoul, Republic of Korea, 140-742"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Sookmyung Women's University 1 \u00a0 1 \u00a0 \u00a0 Hyochangwongil 52, Youngsan-gu, Seoul, Republic of Korea, 140-742","institution_ids":["https://openalex.org/I31766871"]},{"raw_affiliation_string":"Research Center for Women's Diseases (RCWD), Sookmyung Women's University 2 \u00a0 2 \u00a0 \u00a0 Hyochangwongil 52, Youngsan-gu, Seoul, Republic of Korea, 140-742","institution_ids":["https://openalex.org/I31766871"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082247143","display_name":"Jiwon Choi","orcid":"https://orcid.org/0000-0002-0786-6187"},"institutions":[{"id":"https://openalex.org/I31766871","display_name":"Sookmyung Women's University","ror":"https://ror.org/00vvvt117","country_code":"KR","type":"education","lineage":["https://openalex.org/I31766871"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jiwon Choi","raw_affiliation_strings":["Department of Biological Sciences, Sookmyung Women's University 1 \u00a0 1 \u00a0 \u00a0 Hyochangwongil 52, Youngsan-gu, Seoul, Republic of Korea, 140-742"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Sookmyung Women's University 1 \u00a0 1 \u00a0 \u00a0 Hyochangwongil 52, Youngsan-gu, Seoul, Republic of Korea, 140-742","institution_ids":["https://openalex.org/I31766871"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013872257","display_name":"Jeeweon Seong","orcid":null},"institutions":[{"id":"https://openalex.org/I31766871","display_name":"Sookmyung Women's University","ror":"https://ror.org/00vvvt117","country_code":"KR","type":"education","lineage":["https://openalex.org/I31766871"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jeeweon Seong","raw_affiliation_strings":["Department of Biological Sciences, Sookmyung Women's University 1 \u00a0 1 \u00a0 \u00a0 Hyochangwongil 52, Youngsan-gu, Seoul, Republic of Korea, 140-742"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Sookmyung Women's University 1 \u00a0 1 \u00a0 \u00a0 Hyochangwongil 52, Youngsan-gu, Seoul, Republic of Korea, 140-742","institution_ids":["https://openalex.org/I31766871"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5032052510"],"corresponding_institution_ids":["https://openalex.org/I31766871"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":1.0904,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.75633649,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"22","issue":"23","first_page":"2898","last_page":"2904"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9815000295639038,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9815000295639038,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microarray-databases","display_name":"Microarray databases","score":0.7025794982910156},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.6344289779663086},{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.6035544276237488},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.4886515438556671},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4818647801876068},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.4595337212085724},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"Gene expression profiling","score":0.45819079875946045},{"id":"https://openalex.org/keywords/microarray","display_name":"Microarray","score":0.45087406039237976},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4438937306404114},{"id":"https://openalex.org/keywords/gene-chip-analysis","display_name":"Gene chip analysis","score":0.441417396068573},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.40616828203201294},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.39582252502441406},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3752598762512207},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.355500191450119},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.33977627754211426},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.29232239723205566},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.25817328691482544}],"concepts":[{"id":"https://openalex.org/C548314002","wikidata":"https://www.wikidata.org/wiki/Q6839218","display_name":"Microarray databases","level":5,"score":0.7025794982910156},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6344289779663086},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.6035544276237488},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.4886515438556671},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4818647801876068},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.4595337212085724},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.45819079875946045},{"id":"https://openalex.org/C186836561","wikidata":"https://www.wikidata.org/wiki/Q1931516","display_name":"Microarray","level":4,"score":0.45087406039237976},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4438937306404114},{"id":"https://openalex.org/C24361400","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Gene chip analysis","level":5,"score":0.441417396068573},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.40616828203201294},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.39582252502441406},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3752598762512207},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.355500191450119},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.33977627754211426},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.29232239723205566},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.25817328691482544},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btl500","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl500","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/23/2898/782600/btl500.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:17032674","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17032674","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btl500","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl500","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/23/2898/782600/btl500.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1985958957","https://openalex.org/W2020541351","https://openalex.org/W2025618966","https://openalex.org/W2035421116","https://openalex.org/W2038437697","https://openalex.org/W2044367627","https://openalex.org/W2100668965","https://openalex.org/W2106617991","https://openalex.org/W2107989651","https://openalex.org/W2109972881","https://openalex.org/W2116634113","https://openalex.org/W2119274294","https://openalex.org/W2120865735","https://openalex.org/W2122598723","https://openalex.org/W2123106337","https://openalex.org/W2137466745","https://openalex.org/W2137476312","https://openalex.org/W2164518522","https://openalex.org/W2167980479"],"related_works":["https://openalex.org/W2796636403","https://openalex.org/W2183420549","https://openalex.org/W74695042","https://openalex.org/W2998765584","https://openalex.org/W2053053668","https://openalex.org/W2900947575","https://openalex.org/W2089338936","https://openalex.org/W2137073600","https://openalex.org/W2160313795","https://openalex.org/W2392430783"],"abstract_inverted_index":{"MOTIVATION:":[0],"The":[1,44,77],"identification":[2,183],"of":[3,6,20,54,61,79,83,104,116,126,168,184,206],"the":[4,35,49,52,65,87,101,113,124,142,166,172,182,199,204],"change":[5],"gene":[7,39,106,129],"expression":[8,40,102,143],"in":[9,38,57,90,112,171],"multifactorial":[10],"diseases,":[11],"such":[12,93],"as":[13,94],"breast":[14,127,138,148],"cancer":[15,149],"is":[16,46],"a":[17,27,58,80,105,177],"major":[18],"goal":[19],"DNA":[21],"microarray":[22,42,169,208],"experiments.":[23],"Here":[24],"we":[25],"present":[26,200],"new":[28],"data":[29,170,209],"mining":[30],"strategy":[31],"to":[32,99,159,197],"better":[33],"analyze":[34],"marginal":[36,152],"difference":[37,144],"between":[41,74,145],"samples.":[43,75],"idea":[45],"based":[47],"on":[48,68],"notion":[50],"that":[51],"consideration":[53],"gene's":[55],"behavior":[56],"wide":[59,114],"variety":[60,115],"experiments":[62],"can":[63],"improve":[64],"statistical":[66],"reliability":[67],"identifying":[69],"genes":[70,135],"with":[71,137],"moderate":[72],"changes":[73],"RESULTS:":[76],"availability":[78],"large":[81],"collection":[82],"array":[84],"samples":[85],"sharing":[86],"same":[88],"platform":[89],"public":[91,173],"databases,":[92],"NCBI":[95],"GEO,":[96],"enabled":[97],"us":[98],"re-standardize":[100],"intensity":[103],"using":[107,161],"its":[108],"mean":[109],"and":[110,147,153],"variation":[111],"experimental":[117],"conditions.":[118],"This":[119],"approach":[120,202],"was":[121,151,195],"evaluated":[122],"via":[123],"re-identification":[125],"cancer-specific":[128],"expression.":[130],"It":[131],"successfully":[132],"prioritized":[133],"several":[134],"associated":[136],"tumor,":[139],"for":[140,181,203],"which":[141],"normal":[146],"cells":[150],"thus":[154],"would":[155],"have":[156],"been":[157],"difficult":[158],"recognize":[160],"conventional":[162],"analysis":[163,205],"methods.":[164],"Maximizing":[165],"utility":[167],"database,":[174],"it":[175],"provides":[176],"valuable":[178],"tool":[179],"particularly":[180],"previously":[185],"unrecognized":[186],"disease-related":[187],"genes.":[188],"AVAILABILITY:":[189],"A":[190],"user":[191],"friendly":[192],"web-interface":[193],"(http://compbio.sookmyung.ac.kr/~lage/)":[194],"constructed":[196],"provide":[198],"large-scale":[201],"GEO":[207],"(GS-LAGE":[210],"server).":[211]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}