{"id":"https://openalex.org/W2113971181","doi":"https://doi.org/10.1093/bioinformatics/btl448","title":"Anisotropic network model: systematic evaluation and a new web interface","display_name":"Anisotropic network model: systematic evaluation and a new web interface","publication_year":2006,"publication_date":"2006-08-23","ids":{"openalex":"https://openalex.org/W2113971181","doi":"https://doi.org/10.1093/bioinformatics/btl448","mag":"2113971181","pmid":"https://pubmed.ncbi.nlm.nih.gov/16928735"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btl448","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl448","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/21/2619/48839900/bioinformatics_22_21_2619.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/22/21/2619/48839900/bioinformatics_22_21_2619.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033599763","display_name":"Eran Eyal","orcid":"https://orcid.org/0000-0002-9505-6319"},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Eran Eyal","raw_affiliation_strings":["Department of Computational Biology, School of Medicine, University of Pittsburgh \u00a0 PA 15213, USA","Department of Computational Biology, School of Medicine, University of Pittsburgh PA 15213, USA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, School of Medicine, University of Pittsburgh \u00a0 PA 15213, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Computational Biology, School of Medicine, University of Pittsburgh PA 15213, USA#TAB#","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003311977","display_name":"Lee\u2010Wei Yang","orcid":"https://orcid.org/0000-0002-3971-6386"},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lee-Wei Yang","raw_affiliation_strings":["Department of Computational Biology, School of Medicine, University of Pittsburgh \u00a0 PA 15213, USA","Department of Computational Biology, School of Medicine, University of Pittsburgh PA 15213, USA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, School of Medicine, University of Pittsburgh \u00a0 PA 15213, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Computational Biology, School of Medicine, University of Pittsburgh PA 15213, USA#TAB#","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081814496","display_name":"\u0130vet Bahar","orcid":"https://orcid.org/0000-0001-9959-4176"},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ivet Bahar","raw_affiliation_strings":["Department of Computational Biology, School of Medicine, University of Pittsburgh \u00a0 PA 15213, USA","Department of Computational Biology, School of Medicine, University of Pittsburgh PA 15213, USA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, School of Medicine, University of Pittsburgh \u00a0 PA 15213, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Computational Biology, School of Medicine, University of Pittsburgh PA 15213, USA#TAB#","institution_ids":["https://openalex.org/I170201317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5033599763"],"corresponding_institution_ids":["https://openalex.org/I170201317"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":6.1348,"has_fulltext":true,"cited_by_count":329,"citation_normalized_percentile":{"value":0.97215497,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"22","issue":"21","first_page":"2619","last_page":"2627"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.007400000002235174,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7739815711975098},{"id":"https://openalex.org/keywords/anisotropy","display_name":"Anisotropy","score":0.5917513370513916},{"id":"https://openalex.org/keywords/web-server","display_name":"Web server","score":0.5516282320022583},{"id":"https://openalex.org/keywords/interface","display_name":"Interface (matter)","score":0.5229683518409729},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.456916868686676},{"id":"https://openalex.org/keywords/graphical-user-interface","display_name":"Graphical user interface","score":0.4504578411579132},{"id":"https://openalex.org/keywords/animation","display_name":"Animation","score":0.4292471408843994},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.4152825176715851},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3961772322654724},{"id":"https://openalex.org/keywords/computational-science","display_name":"Computational science","score":0.3706035017967224},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.355948269367218},{"id":"https://openalex.org/keywords/the-internet","display_name":"The Internet","score":0.2557032108306885},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.18656933307647705},{"id":"https://openalex.org/keywords/computer-graphics","display_name":"Computer graphics (images)","score":0.15455621480941772},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.12496328353881836},{"id":"https://openalex.org/keywords/operating-system","display_name":"Operating system","score":0.10794439911842346},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.09033659100532532},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.085807204246521}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7739815711975098},{"id":"https://openalex.org/C85725439","wikidata":"https://www.wikidata.org/wiki/Q466686","display_name":"Anisotropy","level":2,"score":0.5917513370513916},{"id":"https://openalex.org/C11392498","wikidata":"https://www.wikidata.org/wiki/Q11288","display_name":"Web server","level":3,"score":0.5516282320022583},{"id":"https://openalex.org/C113843644","wikidata":"https://www.wikidata.org/wiki/Q901882","display_name":"Interface (matter)","level":4,"score":0.5229683518409729},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.456916868686676},{"id":"https://openalex.org/C37789001","wikidata":"https://www.wikidata.org/wiki/Q782543","display_name":"Graphical user interface","level":2,"score":0.4504578411579132},{"id":"https://openalex.org/C502989409","wikidata":"https://www.wikidata.org/wiki/Q11425","display_name":"Animation","level":2,"score":0.4292471408843994},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.4152825176715851},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3961772322654724},{"id":"https://openalex.org/C459310","wikidata":"https://www.wikidata.org/wiki/Q117801","display_name":"Computational science","level":1,"score":0.3706035017967224},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.355948269367218},{"id":"https://openalex.org/C110875604","wikidata":"https://www.wikidata.org/wiki/Q75","display_name":"The Internet","level":2,"score":0.2557032108306885},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.18656933307647705},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.15455621480941772},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.12496328353881836},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.10794439911842346},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09033659100532532},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.085807204246521},{"id":"https://openalex.org/C157915830","wikidata":"https://www.wikidata.org/wiki/Q2928001","display_name":"Bubble","level":2,"score":0.0},{"id":"https://openalex.org/C129307140","wikidata":"https://www.wikidata.org/wiki/Q6795880","display_name":"Maximum bubble pressure method","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008956","descriptor_name":"Models, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008956","descriptor_name":"Models, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008956","descriptor_name":"Models, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012986","descriptor_name":"Software Validation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012986","descriptor_name":"Software Validation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012986","descriptor_name":"Software Validation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016880","descriptor_name":"Anisotropy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016880","descriptor_name":"Anisotropy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016880","descriptor_name":"Anisotropy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btl448","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl448","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/21/2619/48839900/bioinformatics_22_21_2619.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:16928735","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16928735","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.97.9987","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.97.9987","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://bioinformatics.oxfordjournals.org/cgi/reprint/btl448v1.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btl448","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl448","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/21/2619/48839900/bioinformatics_22_21_2619.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309036","display_name":"Purdue University","ror":"https://ror.org/02dqehb95"},{"id":"https://openalex.org/F4320310174","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2113971181.pdf","grobid_xml":"https://content.openalex.org/works/W2113971181.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W255996521","https://openalex.org/W610636697","https://openalex.org/W1968407616","https://openalex.org/W1972244704","https://openalex.org/W1977242895","https://openalex.org/W1977782382","https://openalex.org/W1991762941","https://openalex.org/W2000544785","https://openalex.org/W2004067483","https://openalex.org/W2008708467","https://openalex.org/W2021646539","https://openalex.org/W2022950330","https://openalex.org/W2029667189","https://openalex.org/W2052612332","https://openalex.org/W2069777230","https://openalex.org/W2072458217","https://openalex.org/W2080655845","https://openalex.org/W2085277871","https://openalex.org/W2086939340","https://openalex.org/W2087284052","https://openalex.org/W2100284567","https://openalex.org/W2101017457","https://openalex.org/W2101766243","https://openalex.org/W2102211745","https://openalex.org/W2102449622","https://openalex.org/W2107268733","https://openalex.org/W2108700551","https://openalex.org/W2112315506","https://openalex.org/W2113994268","https://openalex.org/W2116498327","https://openalex.org/W2118733486","https://openalex.org/W2119891507","https://openalex.org/W2123035826","https://openalex.org/W2123123142","https://openalex.org/W2125063886","https://openalex.org/W2125626635","https://openalex.org/W2129187661","https://openalex.org/W2129472062","https://openalex.org/W2130479394","https://openalex.org/W2134528197","https://openalex.org/W2142960527","https://openalex.org/W2144646547","https://openalex.org/W2145961753","https://openalex.org/W2146249023","https://openalex.org/W2146770788","https://openalex.org/W2148455468","https://openalex.org/W2151759496","https://openalex.org/W2153049516","https://openalex.org/W2153304705","https://openalex.org/W2153561236","https://openalex.org/W2155812479","https://openalex.org/W2156115459","https://openalex.org/W2158528359","https://openalex.org/W2160975112","https://openalex.org/W2164507558","https://openalex.org/W4321317585"],"related_works":["https://openalex.org/W2532377291","https://openalex.org/W2000013817","https://openalex.org/W4296190881","https://openalex.org/W2366362996","https://openalex.org/W2517624617","https://openalex.org/W2378422373","https://openalex.org/W2129566390","https://openalex.org/W2360905385","https://openalex.org/W2384288141","https://openalex.org/W2944930475"],"abstract_inverted_index":{"MOTIVATION:":[0],"The":[1],"Anisotropic":[2],"Network":[3],"Model":[4],"(ANM)":[5],"is":[6,114,131],"a":[7,38,55],"simple":[8],"yet":[9],"powerful":[10],"model":[11,64,139],"for":[12,22,46,128,137],"normal":[13],"mode":[14],"analysis":[15],"of":[16,37,58,77,121,146],"proteins.":[17],"Despite":[18],"its":[19,75],"broad":[20],"use":[21],"exploring":[23],"biomolecular":[24],"collective":[25,147],"motions,":[26],"ANM":[27,50,129,154],"has":[28,41,51],"not":[29],"been":[30,42,52],"systematically":[31],"evaluated":[32,53],"to":[33,60,88],"date.":[34],"A":[35,125],"lack":[36],"convenient":[39],"interface":[40],"an":[43],"additional":[44],"obstacle":[45],"easy":[47],"usage.":[48],"RESULTS:":[49],"on":[54],"large":[56],"set":[57],"proteins":[59,85],"establish":[61],"the":[62,68,119,122],"optimal":[63],"parameters":[65,140],"that":[66],"achieve":[67],"highest":[69],"correlation":[70],"with":[71,112,116],"experimental":[72],"data":[73],"and":[74,79,98,141,149],"limits":[76],"accuracy":[78],"applicability.":[80],"Residue":[81],"fluctuations":[82],"in":[83,95,110,118],"globular":[84],"are":[86,101],"shown":[87],"be":[89],"more":[90,102],"accurately":[91,103],"predicted":[92],"than":[93,105],"those":[94],"nonglobular":[96],"proteins,":[97],"core":[99],"residues":[100],"described":[104],"solvent-exposed":[106],"ones.":[107],"Significant":[108],"improvement":[109],"agreement":[111],"experiments":[113],"observed":[115],"increase":[117],"resolution":[120],"examined":[123],"structure.":[124],"new":[126],"server":[127,155],"calculations":[130],"presented,":[132],"which":[133],"offers":[134],"flexible":[135],"options":[136],"controlling":[138],"output":[142],"formats,":[143],"interactive":[144],"animation":[145],"modes":[148],"advanced":[150],"graphical":[151],"features.":[152],"AVAILABILITY:":[153],"(http://www.ccbb.pitt.edu/anm)":[156]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":21},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":15},{"year":2018,"cited_by_count":12},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":18},{"year":2015,"cited_by_count":26},{"year":2014,"cited_by_count":21},{"year":2013,"cited_by_count":24},{"year":2012,"cited_by_count":19}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}