{"id":"https://openalex.org/W2127037564","doi":"https://doi.org/10.1093/bioinformatics/btl202","title":"Identification of metabolic units induced by environmental signals","display_name":"Identification of metabolic units induced by environmental signals","publication_year":2006,"publication_date":"2006-07-15","ids":{"openalex":"https://openalex.org/W2127037564","doi":"https://doi.org/10.1093/bioinformatics/btl202","mag":"2127037564","pmid":"https://pubmed.ncbi.nlm.nih.gov/16873496"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btl202","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl202","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/14/e375/48841305/bioinformatics_22_14_e375.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/22/14/e375/48841305/bioinformatics_22_14_e375.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029985835","display_name":"Jose C. Nacher","orcid":"https://orcid.org/0000-0002-7187-6152"},"institutions":[{"id":"https://openalex.org/I4210088032","display_name":"Kyoto Bunkyo University","ror":"https://ror.org/0037an472","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210088032"]},{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I4399598384","display_name":"Kyoto University Institute for Chemical Research","ror":"https://ror.org/0349bbg69","country_code":null,"type":"facility","lineage":["https://openalex.org/I22299242","https://openalex.org/I4399598384"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Jose C. Nacher","raw_affiliation_strings":["Bioinformatics Center, Institute for Chemical Research, Kyoto University Uji \u00a0 Kyoto 611-0011, Japan"],"affiliations":[{"raw_affiliation_string":"Bioinformatics Center, Institute for Chemical Research, Kyoto University Uji \u00a0 Kyoto 611-0011, Japan","institution_ids":["https://openalex.org/I4210088032","https://openalex.org/I22299242","https://openalex.org/I4399598384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046134592","display_name":"Jean\u2010Marc Schwartz","orcid":"https://orcid.org/0000-0002-6472-0184"},"institutions":[{"id":"https://openalex.org/I4210088032","display_name":"Kyoto Bunkyo University","ror":"https://ror.org/0037an472","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210088032"]},{"id":"https://openalex.org/I4399598384","display_name":"Kyoto University Institute for Chemical Research","ror":"https://ror.org/0349bbg69","country_code":null,"type":"facility","lineage":["https://openalex.org/I22299242","https://openalex.org/I4399598384"]},{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Jean-Marc Schwartz","raw_affiliation_strings":["Bioinformatics Center, Institute for Chemical Research, Kyoto University Uji \u00a0 Kyoto 611-0011, Japan"],"affiliations":[{"raw_affiliation_string":"Bioinformatics Center, Institute for Chemical Research, Kyoto University Uji \u00a0 Kyoto 611-0011, Japan","institution_ids":["https://openalex.org/I4210088032","https://openalex.org/I22299242","https://openalex.org/I4399598384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058022821","display_name":"Minoru Kanehisa","orcid":"https://orcid.org/0000-0001-6123-540X"},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I4399598384","display_name":"Kyoto University Institute for Chemical Research","ror":"https://ror.org/0349bbg69","country_code":null,"type":"facility","lineage":["https://openalex.org/I22299242","https://openalex.org/I4399598384"]},{"id":"https://openalex.org/I4210088032","display_name":"Kyoto Bunkyo University","ror":"https://ror.org/0037an472","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210088032"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Minoru Kanehisa","raw_affiliation_strings":["Bioinformatics Center, Institute for Chemical Research, Kyoto University Uji \u00a0 Kyoto 611-0011, Japan"],"affiliations":[{"raw_affiliation_string":"Bioinformatics Center, Institute for Chemical Research, Kyoto University Uji \u00a0 Kyoto 611-0011, Japan","institution_ids":["https://openalex.org/I4210088032","https://openalex.org/I22299242","https://openalex.org/I4399598384"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016330265","display_name":"Tatsuya Akutsu","orcid":"https://orcid.org/0000-0001-9763-797X"},"institutions":[{"id":"https://openalex.org/I4210088032","display_name":"Kyoto Bunkyo University","ror":"https://ror.org/0037an472","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210088032"]},{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I4399598384","display_name":"Kyoto University Institute for Chemical Research","ror":"https://ror.org/0349bbg69","country_code":null,"type":"facility","lineage":["https://openalex.org/I22299242","https://openalex.org/I4399598384"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tatsuya Akutsu","raw_affiliation_strings":["Bioinformatics Center, Institute for Chemical Research, Kyoto University Uji \u00a0 Kyoto 611-0011, Japan"],"affiliations":[{"raw_affiliation_string":"Bioinformatics Center, Institute for Chemical Research, Kyoto University Uji \u00a0 Kyoto 611-0011, Japan","institution_ids":["https://openalex.org/I4210088032","https://openalex.org/I22299242","https://openalex.org/I4399598384"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5029985835"],"corresponding_institution_ids":["https://openalex.org/I22299242","https://openalex.org/I4210088032","https://openalex.org/I4399598384"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.2724,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.58674651,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"22","issue":"14","first_page":"e375","last_page":"e383"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.7044594287872314},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.6794552206993103},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6530594825744629},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5675663352012634},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.5407356023788452},{"id":"https://openalex.org/keywords/psychological-repression","display_name":"Psychological repression","score":0.533537745475769},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.530704915523529},{"id":"https://openalex.org/keywords/variety","display_name":"Variety (cybernetics)","score":0.49694088101387024},{"id":"https://openalex.org/keywords/metabolic-network","display_name":"Metabolic network","score":0.45661231875419617},{"id":"https://openalex.org/keywords/yeast","display_name":"Yeast","score":0.43188390135765076},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.3842596113681793},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.364352285861969},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.28497809171676636},{"id":"https://openalex.org/keywords/ecology","display_name":"Ecology","score":0.09739339351654053},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.0727626383304596}],"concepts":[{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.7044594287872314},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6794552206993103},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6530594825744629},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5675663352012634},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5407356023788452},{"id":"https://openalex.org/C186310378","wikidata":"https://www.wikidata.org/wiki/Q941796","display_name":"Psychological repression","level":4,"score":0.533537745475769},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.530704915523529},{"id":"https://openalex.org/C136197465","wikidata":"https://www.wikidata.org/wiki/Q1729295","display_name":"Variety (cybernetics)","level":2,"score":0.49694088101387024},{"id":"https://openalex.org/C101810790","wikidata":"https://www.wikidata.org/wiki/Q2263094","display_name":"Metabolic network","level":2,"score":0.45661231875419617},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.43188390135765076},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.3842596113681793},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.364352285861969},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.28497809171676636},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.09739339351654053},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.0727626383304596}],"mesh":[{"descriptor_ui":"D000222","descriptor_name":"Adaptation, Physiological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000222","descriptor_name":"Adaptation, Physiological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000222","descriptor_name":"Adaptation, Physiological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004777","descriptor_name":"Environment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004777","descriptor_name":"Environment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004777","descriptor_name":"Environment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1093/bioinformatics/btl202","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl202","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/14/e375/48841305/bioinformatics_22_14_e375.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:16873496","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16873496","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/931b380a-b529-4728-bd40-ad3e4c5afefc","is_oa":false,"landing_page_url":"https://research.manchester.ac.uk/en/publications/931b380a-b529-4728-bd40-ad3e4c5afefc","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nacher, J C, Schwartz, J M, Kanehisa, M & Akutsu, T 2006, 'Identification of metabolic units induced by environmental signals', Bioinformatics, vol. 22, no. 14, pp. e375-e383. https://doi.org/10.1093/bioinformatics/btl202","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:irdb.nii.ac.jp:01406:0005257816","is_oa":false,"landing_page_url":"https://fun.repo.nii.ac.jp/records/5027","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"journal article"},{"id":"pmh:oai:pure.atira.dk:publications/931b380a-b529-4728-bd40-ad3e4c5afefc","is_oa":false,"landing_page_url":"https://www.research.manchester.ac.uk/portal/en/publications/identification-of-metabolic-units-induced-by-environmental-signals(931b380a-b529-4728-bd40-ad3e4c5afefc).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nacher, J C, Schwartz, J M, Kanehisa, M & Akutsu, T 2006, 'Identification of metabolic units induced by environmental signals', Bioinformatics, vol. 22, no. 14, pp. e375-e383. https://doi.org/10.1093/bioinformatics/btl202","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btl202","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl202","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/14/e375/48841305/bioinformatics_22_14_e375.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7200000286102295,"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2127037564.pdf","grobid_xml":"https://content.openalex.org/works/W2127037564.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W1556857123","https://openalex.org/W1579822124","https://openalex.org/W1627599966","https://openalex.org/W1758395617","https://openalex.org/W1763161027","https://openalex.org/W1976544696","https://openalex.org/W1983202741","https://openalex.org/W2006367501","https://openalex.org/W2006873092","https://openalex.org/W2008620264","https://openalex.org/W2009163705","https://openalex.org/W2015519162","https://openalex.org/W2021239799","https://openalex.org/W2028561804","https://openalex.org/W2037433020","https://openalex.org/W2037614307","https://openalex.org/W2048596679","https://openalex.org/W2049484314","https://openalex.org/W2069898971","https://openalex.org/W2108859156","https://openalex.org/W2109363337","https://openalex.org/W2112090702","https://openalex.org/W2112609377","https://openalex.org/W2113004492","https://openalex.org/W2124724728","https://openalex.org/W2137683543","https://openalex.org/W2142913541","https://openalex.org/W2148061480","https://openalex.org/W2153373497","https://openalex.org/W2163480486","https://openalex.org/W2165011536","https://openalex.org/W2165674132","https://openalex.org/W2167119716","https://openalex.org/W2168846334","https://openalex.org/W3103786587","https://openalex.org/W4298203020"],"related_works":["https://openalex.org/W1543402492","https://openalex.org/W2117627298","https://openalex.org/W1985297433","https://openalex.org/W1966072876","https://openalex.org/W4315558101","https://openalex.org/W2108557660","https://openalex.org/W2028107853","https://openalex.org/W1982584572","https://openalex.org/W4232406862","https://openalex.org/W2397070560"],"abstract_inverted_index":{"We":[0,35,69],"present":[1],"here":[2],"a":[3,66,106],"correlation-based":[4],"analysis":[5],"for":[6],"identifying":[7],"the":[8,25,45,48,80,86,90],"expression":[9,74],"response":[10,27,50],"of":[11,28,47,79,89],"genes":[12,60],"involved":[13],"in":[14,103],"metabolism":[15],"to":[16,23,31,41,51,58,65,111,115],"specific":[17],"external":[18],"signals,":[19],"and":[20,55,84,102],"apply":[21],"it":[22],"analyze":[24,85],"transcriptional":[26],"Saccharomyces":[29],"cerevisiae":[30],"different":[32],"stress":[33],"conditions.":[34],"show":[36],"that":[37,61],"this":[38],"approach":[39],"leads":[40],"new":[42],"insights":[43],"about":[44],"specificity":[46],"genomic":[49],"given":[52],"environmental":[53],"changes,":[54],"allows":[56],"us":[57],"identify":[59],"are":[62],"particularly":[63],"sensitive":[64],"unique":[67],"condition.":[68],"then":[70],"integrate":[71],"these":[72],"signal-induced":[73],"data":[75,78],"with":[76],"structural":[77],"yeast":[81],"metabolic":[82,117],"network":[83],"topological":[87],"properties":[88],"induced":[91],"or":[92],"repressed":[93],"subnetworks.":[94],"They":[95],"reveal":[96],"significant":[97],"discrepancies":[98],"from":[99],"random":[100],"networks,":[101],"particular":[104],"exhibit":[105],"high":[107],"connectivity,":[108],"allowing":[109],"them":[110],"be":[112],"mapped":[113],"back":[114],"complete":[116],"routes.":[118]},"counts_by_year":[],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}