{"id":"https://openalex.org/W2120024428","doi":"https://doi.org/10.1093/bioinformatics/btl140","title":"Improved scoring of functional groups from gene expression data by decorrelating GO graph structure","display_name":"Improved scoring of functional groups from gene expression data by decorrelating GO graph structure","publication_year":2006,"publication_date":"2006-04-10","ids":{"openalex":"https://openalex.org/W2120024428","doi":"https://doi.org/10.1093/bioinformatics/btl140","mag":"2120024428","pmid":"https://pubmed.ncbi.nlm.nih.gov/16606683"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btl140","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl140","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/13/1600/482171/btl140.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/22/13/1600/482171/btl140.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041745241","display_name":"Adrian Alexa","orcid":null},"institutions":[{"id":"https://openalex.org/I4210109712","display_name":"Max Planck Institute for Informatics","ror":"https://ror.org/01w19ak89","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210109712"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Adrian Alexa","raw_affiliation_strings":["Max-Planck-Institute for Informatics \u00a0 Stuhlsatzenhausweg 85, D-66123 Saarbr\u00fccken, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max-Planck-Institute for Informatics \u00a0 Stuhlsatzenhausweg 85, D-66123 Saarbr\u00fccken, Germany","institution_ids":["https://openalex.org/I4210109712"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075610512","display_name":"J\u00f6rg Rahnenf\u00fchrer","orcid":"https://orcid.org/0000-0002-8947-440X"},"institutions":[{"id":"https://openalex.org/I4210109712","display_name":"Max Planck Institute for Informatics","ror":"https://ror.org/01w19ak89","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210109712"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J\u00f6rg Rahnenf\u00fchrer","raw_affiliation_strings":["Max-Planck-Institute for Informatics \u00a0 Stuhlsatzenhausweg 85, D-66123 Saarbr\u00fccken, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max-Planck-Institute for Informatics \u00a0 Stuhlsatzenhausweg 85, D-66123 Saarbr\u00fccken, Germany","institution_ids":["https://openalex.org/I4210109712"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023556977","display_name":"Thomas Lengauer","orcid":"https://orcid.org/0000-0003-3801-2640"},"institutions":[{"id":"https://openalex.org/I4210109712","display_name":"Max Planck Institute for Informatics","ror":"https://ror.org/01w19ak89","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210109712"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thomas Lengauer","raw_affiliation_strings":["Max-Planck-Institute for Informatics \u00a0 Stuhlsatzenhausweg 85, D-66123 Saarbr\u00fccken, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max-Planck-Institute for Informatics \u00a0 Stuhlsatzenhausweg 85, D-66123 Saarbr\u00fccken, Germany","institution_ids":["https://openalex.org/I4210109712"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5041745241"],"corresponding_institution_ids":["https://openalex.org/I4210109712"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":12.3277,"has_fulltext":true,"cited_by_count":2406,"citation_normalized_percentile":{"value":0.99343697,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"22","issue":"13","first_page":"1600","last_page":"1607"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9402999877929688,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9402999877929688,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.051500000059604645,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6801879405975342},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.5499765276908875},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.5201409459114075},{"id":"https://openalex.org/keywords/gene-nomenclature","display_name":"Gene nomenclature","score":0.5090031623840332},{"id":"https://openalex.org/keywords/gene-ontology","display_name":"Gene ontology","score":0.43825358152389526},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.3796079158782959},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.28012609481811523},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.26755839586257935},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1602884829044342},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.09525230526924133}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6801879405975342},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.5499765276908875},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.5201409459114075},{"id":"https://openalex.org/C62177273","wikidata":"https://www.wikidata.org/wiki/Q5531556","display_name":"Gene nomenclature","level":4,"score":0.5090031623840332},{"id":"https://openalex.org/C2987395477","wikidata":"https://www.wikidata.org/wiki/Q135085","display_name":"Gene ontology","level":4,"score":0.43825358152389526},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.3796079158782959},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.28012609481811523},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.26755839586257935},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1602884829044342},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09525230526924133},{"id":"https://openalex.org/C514705636","wikidata":"https://www.wikidata.org/wiki/Q863247","display_name":"Nomenclature","level":3,"score":0.0},{"id":"https://openalex.org/C58642233","wikidata":"https://www.wikidata.org/wiki/Q8269924","display_name":"Taxonomy (biology)","level":2,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btl140","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl140","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/13/1600/482171/btl140.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:16606683","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16606683","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:edoc.mpg.de:314665","is_oa":false,"landing_page_url":"http://edoc.mpg.de/314665","pdf_url":null,"source":{"id":"https://openalex.org/S4406922265","display_name":"Max Planck Institute for Plasma Physics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics, v.22, 1600-1607 (2006)","raw_type":"Article"},{"id":"pmh:oai:pure.mpg.de:item_1328440","is_oa":false,"landing_page_url":"http://hdl.handle.net/11858/00-001M-0000-000F-232C-1","pdf_url":null,"source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btl140","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl140","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/13/1600/482171/btl140.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G8935293790","display_name":"Verbundprojekt: Nationales Genomforschungsnetz, 2. Phase, SMP-Bioinformatik, Anteil MPI f\u00fcr Informatik, Saarbr\u00fccken","funder_award_id":"01GR0453","funder_id":"https://openalex.org/F4320321114","funder_display_name":"Bundesministerium f\u00fcr Bildung und Forschung"}],"funders":[{"id":"https://openalex.org/F4320321114","display_name":"Bundesministerium f\u00fcr Bildung und Forschung","ror":"https://ror.org/04pz7b180"},{"id":"https://openalex.org/F4320327553","display_name":"International Max Planck Research School for Advanced Methods in Process and Systems Engineering","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2120024428.pdf","grobid_xml":"https://content.openalex.org/works/W2120024428.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W1493403933","https://openalex.org/W1527927437","https://openalex.org/W1535641839","https://openalex.org/W1596515083","https://openalex.org/W2045638068","https://openalex.org/W2068517117","https://openalex.org/W2102992354","https://openalex.org/W2103017472","https://openalex.org/W2124388496","https://openalex.org/W2130410032","https://openalex.org/W2135230352","https://openalex.org/W2139703939","https://openalex.org/W2147977520","https://openalex.org/W2157688021","https://openalex.org/W2166023446","https://openalex.org/W4210572675","https://openalex.org/W6629392126","https://openalex.org/W6675471023"],"related_works":["https://openalex.org/W2164883151","https://openalex.org/W2136890152","https://openalex.org/W4254832883","https://openalex.org/W4253387775","https://openalex.org/W2110354241","https://openalex.org/W4242623936","https://openalex.org/W2218035302","https://openalex.org/W4296157762","https://openalex.org/W2280208580","https://openalex.org/W1975509791"],"abstract_inverted_index":{"MOTIVATION:":[0],"The":[1,102],"result":[2],"of":[3,12,47,66,81,155],"a":[4,9,26,152],"typical":[5],"microarray":[6],"experiment":[7],"is":[8,20],"long":[10],"list":[11,19],"genes":[13],"with":[14,136],"corresponding":[15],"expression":[16,40,111],"measurements.":[17],"This":[18],"only":[21],"the":[22,44,63,75,79,82,97,130,148],"starting":[23],"point":[24,125],"for":[25,139],"meaningful":[27],"biological":[28,34,158],"interpretation.":[29],"Modern":[30],"methods":[31,60,117,150],"identify":[32],"relevant":[33,127,157],"processes":[35],"or":[36],"functions":[37],"from":[38],"gene":[39,50,110],"data":[41],"by":[42,69],"scoring":[43,95,140],"statistical":[45,83],"significance":[46],"predefined":[48],"functional":[49,141],"groups,":[51],"e.g.":[52],"based":[53],"on":[54,106],"Gene":[55],"Ontology":[56],"(GO).":[57],"We":[58,86,113],"develop":[59],"that":[61,91,115,133,147],"increase":[62],"explanatory":[64],"power":[65],"this":[67],"approach":[68],"integrating":[70],"knowledge":[71],"about":[72],"relationships":[73],"between":[74,121],"GO":[76,93,99,122,131],"terms":[77,123,159],"into":[78],"calculation":[80],"significance.":[84],"RESULTS:":[85],"present":[87],"two":[88],"novel":[89],"algorithms":[90,103,138],"improve":[92],"group":[94],"using":[96],"underlying":[98],"graph":[100,132],"topology.":[101],"are":[104],"evaluated":[105],"real":[107],"and":[108,124],"simulated":[109],"data.":[112],"show":[114],"both":[116],"eliminate":[118],"local":[119],"dependencies":[120],"to":[126],"areas":[128],"in":[129],"remain":[134],"undetected":[135],"state-of-the-art":[137],"terms.":[142],"A":[143],"simulation":[144],"study":[145],"demonstrates":[146],"new":[149],"exhibit":[151],"higher":[153],"level":[154],"detecting":[156],"than":[160],"competing":[161],"methods.":[162]},"counts_by_year":[{"year":2026,"cited_by_count":74},{"year":2025,"cited_by_count":157},{"year":2024,"cited_by_count":227},{"year":2023,"cited_by_count":189},{"year":2022,"cited_by_count":214},{"year":2021,"cited_by_count":253},{"year":2020,"cited_by_count":209},{"year":2019,"cited_by_count":142},{"year":2018,"cited_by_count":149},{"year":2017,"cited_by_count":100},{"year":2016,"cited_by_count":105},{"year":2015,"cited_by_count":99},{"year":2014,"cited_by_count":94},{"year":2013,"cited_by_count":86},{"year":2012,"cited_by_count":83}],"updated_date":"2026-07-25T15:57:00.446498","created_date":"2025-10-10T00:00:00"}