{"id":"https://openalex.org/W2113979998","doi":"https://doi.org/10.1093/bioinformatics/btl090","title":"An effective structure learning method for constructing gene networks","display_name":"An effective structure learning method for constructing gene networks","publication_year":2006,"publication_date":"2006-03-16","ids":{"openalex":"https://openalex.org/W2113979998","doi":"https://doi.org/10.1093/bioinformatics/btl090","mag":"2113979998","pmid":"https://pubmed.ncbi.nlm.nih.gov/16543279"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btl090","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl090","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/11/1367/48838346/bioinformatics_22_11_1367.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/22/11/1367/48838346/bioinformatics_22_11_1367.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100736153","display_name":"Xuewen Chen","orcid":"https://orcid.org/0000-0001-7476-591X"},"institutions":[{"id":"https://openalex.org/I146416000","display_name":"University of Kansas","ror":"https://ror.org/001tmjg57","country_code":"US","type":"education","lineage":["https://openalex.org/I146416000"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Xue-wen Chen","raw_affiliation_strings":["Bioinformatics and Computational Life Sciences Laboratory, Electrical Engineering and Computer Science Department 1 \u00a0 1 \u00a0 \u00a0 1520 West 15th Street \u00a0 \u00a0 Lawrence, KS 66045, USA","The University of Kansas 1 \u00a0 1 \u00a0 \u00a0 1520 West 15th Street \u00a0 \u00a0 Lawrence, KS 66045, USA","Bioinformatics and Computational Life Sciences Laboratory, Electrical Engineering and Computer Science Department 1520 West 15th Street The University of Kansas Lawrence, KS 66045, USA#TAB#"],"affiliations":[{"raw_affiliation_string":"Bioinformatics and Computational Life Sciences Laboratory, Electrical Engineering and Computer Science Department 1 \u00a0 1 \u00a0 \u00a0 1520 West 15th Street \u00a0 \u00a0 Lawrence, KS 66045, USA","institution_ids":[]},{"raw_affiliation_string":"The University of Kansas 1 \u00a0 1 \u00a0 \u00a0 1520 West 15th Street \u00a0 \u00a0 Lawrence, KS 66045, USA","institution_ids":["https://openalex.org/I146416000"]},{"raw_affiliation_string":"Bioinformatics and Computational Life Sciences Laboratory, Electrical Engineering and Computer Science Department 1520 West 15th Street The University of Kansas Lawrence, KS 66045, USA#TAB#","institution_ids":["https://openalex.org/I146416000"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080393333","display_name":"Gopalakrishna Anantha","orcid":null},"institutions":[{"id":"https://openalex.org/I146416000","display_name":"University of Kansas","ror":"https://ror.org/001tmjg57","country_code":"US","type":"education","lineage":["https://openalex.org/I146416000"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gopalakrishna Anantha","raw_affiliation_strings":["Bioinformatics and Computational Life Sciences Laboratory, Electrical Engineering and Computer Science Department 1 \u00a0 1 \u00a0 \u00a0 1520 West 15th Street \u00a0 \u00a0 Lawrence, KS 66045, USA","The University of Kansas 1 \u00a0 1 \u00a0 \u00a0 1520 West 15th Street \u00a0 \u00a0 Lawrence, KS 66045, USA","Bioinformatics and Computational Life Sciences Laboratory, Electrical Engineering and Computer Science Department 1520 West 15th Street The University of Kansas Lawrence, KS 66045, USA#TAB#"],"affiliations":[{"raw_affiliation_string":"Bioinformatics and Computational Life Sciences Laboratory, Electrical Engineering and Computer Science Department 1 \u00a0 1 \u00a0 \u00a0 1520 West 15th Street \u00a0 \u00a0 Lawrence, KS 66045, USA","institution_ids":[]},{"raw_affiliation_string":"The University of Kansas 1 \u00a0 1 \u00a0 \u00a0 1520 West 15th Street \u00a0 \u00a0 Lawrence, KS 66045, USA","institution_ids":["https://openalex.org/I146416000"]},{"raw_affiliation_string":"Bioinformatics and Computational Life Sciences Laboratory, Electrical Engineering and Computer Science Department 1520 West 15th Street The University of Kansas Lawrence, KS 66045, USA#TAB#","institution_ids":["https://openalex.org/I146416000"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100718392","display_name":"Xinkun Wang","orcid":"https://orcid.org/0000-0003-1377-0509"},"institutions":[{"id":"https://openalex.org/I146416000","display_name":"University of Kansas","ror":"https://ror.org/001tmjg57","country_code":"US","type":"education","lineage":["https://openalex.org/I146416000"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xinkun Wang","raw_affiliation_strings":["Higuchi Biosciences Center 2 \u00a0 2 \u00a0 \u00a0 2099 Constant Avenue \u00a0 \u00a0 Lawrence, KS 66047, USA","The University of Kansas 2 \u00a0 2 \u00a0 \u00a0 2099 Constant Avenue \u00a0 \u00a0 Lawrence, KS 66047, USA","Higuchi Biosciences Center 2099 Constant Avenue The University of Kansas Lawrence, KS 66047, USA#TAB#"],"affiliations":[{"raw_affiliation_string":"Higuchi Biosciences Center 2 \u00a0 2 \u00a0 \u00a0 2099 Constant Avenue \u00a0 \u00a0 Lawrence, KS 66047, USA","institution_ids":[]},{"raw_affiliation_string":"The University of Kansas 2 \u00a0 2 \u00a0 \u00a0 2099 Constant Avenue \u00a0 \u00a0 Lawrence, KS 66047, USA","institution_ids":["https://openalex.org/I146416000"]},{"raw_affiliation_string":"Higuchi Biosciences Center 2099 Constant Avenue The University of Kansas Lawrence, KS 66047, USA#TAB#","institution_ids":["https://openalex.org/I146416000"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100736153"],"corresponding_institution_ids":["https://openalex.org/I146416000"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":6.1294,"has_fulltext":true,"cited_by_count":110,"citation_normalized_percentile":{"value":0.97203082,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"22","issue":"11","first_page":"1367","last_page":"1374"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7118473649024963},{"id":"https://openalex.org/keywords/heuristic","display_name":"Heuristic","score":0.6472575664520264},{"id":"https://openalex.org/keywords/bayesian-network","display_name":"Bayesian network","score":0.5862630605697632},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5651260018348694},{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.5588826537132263},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5106285214424133},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.5104174017906189},{"id":"https://openalex.org/keywords/hill-climbing","display_name":"Hill climbing","score":0.46820881962776184},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4473355710506439},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.3316539525985718},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.1897314190864563},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.10908481478691101}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7118473649024963},{"id":"https://openalex.org/C173801870","wikidata":"https://www.wikidata.org/wiki/Q201413","display_name":"Heuristic","level":2,"score":0.6472575664520264},{"id":"https://openalex.org/C33724603","wikidata":"https://www.wikidata.org/wiki/Q812540","display_name":"Bayesian network","level":2,"score":0.5862630605697632},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5651260018348694},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.5588826537132263},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5106285214424133},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.5104174017906189},{"id":"https://openalex.org/C135450995","wikidata":"https://www.wikidata.org/wiki/Q820272","display_name":"Hill climbing","level":2,"score":0.46820881962776184},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4473355710506439},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3316539525985718},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1897314190864563},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10908481478691101},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C13280743","wikidata":"https://www.wikidata.org/wiki/Q131089","display_name":"Geodesy","level":1,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005800","descriptor_name":"Genes, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005800","descriptor_name":"Genes, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005800","descriptor_name":"Genes, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btl090","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl090","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/11/1367/48838346/bioinformatics_22_11_1367.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:16543279","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16543279","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.99.7962","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.99.7962","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://bioinformatics.oxfordjournals.org/cgi/reprint/btl090v1.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btl090","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl090","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/22/11/1367/48838346/bioinformatics_22_11_1367.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306101","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80"},{"id":"https://openalex.org/F4320338283","display_name":"Office of Experimental Program to Stimulate Competitive Research","ror":"https://ror.org/04k9mqs78"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2113979998.pdf","grobid_xml":"https://content.openalex.org/works/W2113979998.grobid-xml"},"referenced_works_count":79,"referenced_works":["https://openalex.org/W119113077","https://openalex.org/W204872640","https://openalex.org/W603809537","https://openalex.org/W1505477995","https://openalex.org/W1517993545","https://openalex.org/W1518816191","https://openalex.org/W1530964327","https://openalex.org/W1559547793","https://openalex.org/W1593794455","https://openalex.org/W1626295059","https://openalex.org/W1698663318","https://openalex.org/W1746680969","https://openalex.org/W1769824028","https://openalex.org/W1817561967","https://openalex.org/W1822300807","https://openalex.org/W1970156673","https://openalex.org/W1975161001","https://openalex.org/W1983690667","https://openalex.org/W1988383139","https://openalex.org/W1989371635","https://openalex.org/W1993189701","https://openalex.org/W2004608252","https://openalex.org/W2008107402","https://openalex.org/W2008906462","https://openalex.org/W2010288201","https://openalex.org/W2013165066","https://openalex.org/W2052006582","https://openalex.org/W2052721939","https://openalex.org/W2061280979","https://openalex.org/W2062818042","https://openalex.org/W2068449035","https://openalex.org/W2084619201","https://openalex.org/W2095622082","https://openalex.org/W2100603120","https://openalex.org/W2103453943","https://openalex.org/W2108020239","https://openalex.org/W2110280725","https://openalex.org/W2110643694","https://openalex.org/W2113654464","https://openalex.org/W2118095601","https://openalex.org/W2124758737","https://openalex.org/W2127305172","https://openalex.org/W2127788692","https://openalex.org/W2128150566","https://openalex.org/W2133476056","https://openalex.org/W2134978629","https://openalex.org/W2136988691","https://openalex.org/W2137661795","https://openalex.org/W2145068337","https://openalex.org/W2151098983","https://openalex.org/W2151268228","https://openalex.org/W2159081670","https://openalex.org/W2159717709","https://openalex.org/W2160533336","https://openalex.org/W2160944125","https://openalex.org/W2161511352","https://openalex.org/W2163076211","https://openalex.org/W2163296727","https://openalex.org/W2170112109","https://openalex.org/W2611370172","https://openalex.org/W2798333393","https://openalex.org/W3023553154","https://openalex.org/W4236354166","https://openalex.org/W4285719527","https://openalex.org/W4388252848","https://openalex.org/W6604832720","https://openalex.org/W6608336699","https://openalex.org/W6630233692","https://openalex.org/W6631858845","https://openalex.org/W6635429209","https://openalex.org/W6636455871","https://openalex.org/W6636664571","https://openalex.org/W6637293442","https://openalex.org/W6638112547","https://openalex.org/W6638557351","https://openalex.org/W6647732023","https://openalex.org/W6663928048","https://openalex.org/W6666075070","https://openalex.org/W6672358642"],"related_works":["https://openalex.org/W4225307033","https://openalex.org/W3124521722","https://openalex.org/W1971648331","https://openalex.org/W2937063873","https://openalex.org/W3154094704","https://openalex.org/W2583008148","https://openalex.org/W2342646320","https://openalex.org/W2074006029","https://openalex.org/W3026534141","https://openalex.org/W2963058055"],"abstract_inverted_index":{"In":[0],"this":[1],"paper,":[2],"we":[3],"present":[4],"a":[5,63],"novel":[6],"structure":[7,45,111],"learning":[8],"method":[9,28,70,87,117,134],"to":[10,94,118],"reconstruct":[11],"the":[12,17,26,44,52,85,95,116,124,129,132],"underlying":[13],"gene":[14,19,119],"networks":[15,90],"from":[16],"observational":[18],"expression":[20,120],"data.":[21],"Unlike":[22],"hill":[23,100],"climbing":[24,101],"approaches,":[25],"proposed":[27,86,133],"first":[29],"constructs":[30],"an":[31],"undirected":[32],"network":[33,76,136],"based":[34],"on":[35],"mutual":[36],"information":[37],"between":[38],"two":[39,56,74],"nodes":[40,57],"and":[41,109,127],"then":[42,59],"splits":[43],"into":[46],"substructures.":[47],"The":[48,81],"directional":[49],"orientations":[50],"for":[51,66,135],"edges":[53],"that":[54,84,91],"connect":[55],"are":[58,92],"obtained":[60],"by":[61],"optimizing":[62],"scoring":[64],"function":[65],"each":[67],"substructure.":[68],"Our":[69],"is":[71],"evaluated":[72],"using":[73],"benchmark":[75],"datasets":[77],"with":[78],"known":[79],"structures.":[80,97],"results":[82],"show":[83,128],"can":[88],"identify":[89],"close":[93],"optimal":[96],"It":[98],"outperforms":[99],"methods":[102],"in":[103],"terms":[104],"of":[105,131],"both":[106],"computation":[107],"time":[108],"predicted":[110],"accuracy.":[112],"We":[113],"also":[114],"apply":[115],"data":[121],"measured":[122],"during":[123],"yeast":[125],"cycle":[126],"effectiveness":[130],"reconstruction.":[137]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":10}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}