{"id":"https://openalex.org/W2129996459","doi":"https://doi.org/10.1093/bioinformatics/btl072","title":"PIANA: protein interactions and network analysis","display_name":"PIANA: protein interactions and network analysis","publication_year":2006,"publication_date":"2006-03-01","ids":{"openalex":"https://openalex.org/W2129996459","doi":"https://doi.org/10.1093/bioinformatics/btl072","mag":"2129996459","pmid":"https://pubmed.ncbi.nlm.nih.gov/16510498"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btl072","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl072","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005359314","display_name":"Ram\u00f3n Arag\u00fc\u00e9s","orcid":null},"institutions":[{"id":"https://openalex.org/I170486558","display_name":"Universitat Pompeu Fabra","ror":"https://ror.org/04n0g0b29","country_code":"ES","type":"education","lineage":["https://openalex.org/I170486558"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Ramon Aragues","raw_affiliation_strings":["Structural Bioinformatics Group (GRIB\u2013IMIM). Departament de Ci\u00e8ncies Experimentals i de la Salut. Universitat Pompeu Fabra \u00a0 C/Doctor Aiguader, 83, Barcelona 08003, Catalonia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Bioinformatics Group (GRIB\u2013IMIM). Departament de Ci\u00e8ncies Experimentals i de la Salut. Universitat Pompeu Fabra \u00a0 C/Doctor Aiguader, 83, Barcelona 08003, Catalonia, Spain","institution_ids":["https://openalex.org/I170486558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082409947","display_name":"Daniel Jaeggi","orcid":null},"institutions":[{"id":"https://openalex.org/I170486558","display_name":"Universitat Pompeu Fabra","ror":"https://ror.org/04n0g0b29","country_code":"ES","type":"education","lineage":["https://openalex.org/I170486558"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Daniel Jaeggi","raw_affiliation_strings":["Structural Bioinformatics Group (GRIB\u2013IMIM). Departament de Ci\u00e8ncies Experimentals i de la Salut. Universitat Pompeu Fabra \u00a0 C/Doctor Aiguader, 83, Barcelona 08003, Catalonia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Bioinformatics Group (GRIB\u2013IMIM). Departament de Ci\u00e8ncies Experimentals i de la Salut. Universitat Pompeu Fabra \u00a0 C/Doctor Aiguader, 83, Barcelona 08003, Catalonia, Spain","institution_ids":["https://openalex.org/I170486558"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111840557","display_name":"Baldo Oliva","orcid":null},"institutions":[{"id":"https://openalex.org/I170486558","display_name":"Universitat Pompeu Fabra","ror":"https://ror.org/04n0g0b29","country_code":"ES","type":"education","lineage":["https://openalex.org/I170486558"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Baldo Oliva","raw_affiliation_strings":["Structural Bioinformatics Group (GRIB\u2013IMIM). Departament de Ci\u00e8ncies Experimentals i de la Salut. Universitat Pompeu Fabra \u00a0 C/Doctor Aiguader, 83, Barcelona 08003, Catalonia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Bioinformatics Group (GRIB\u2013IMIM). Departament de Ci\u00e8ncies Experimentals i de la Salut. Universitat Pompeu Fabra \u00a0 C/Doctor Aiguader, 83, Barcelona 08003, Catalonia, Spain","institution_ids":["https://openalex.org/I170486558"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5005359314","https://openalex.org/A5082409947","https://openalex.org/A5111840557"],"corresponding_institution_ids":["https://openalex.org/I170486558"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":5.0456,"has_fulltext":false,"cited_by_count":68,"citation_normalized_percentile":{"value":0.96111712,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"22","issue":"8","first_page":"1015","last_page":"1017"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9570000171661377,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9570000171661377,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.006899999920278788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11273","display_name":"Advanced Graph Neural Networks","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6086238026618958},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.41780656576156616},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1634618639945984}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6086238026618958},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.41780656576156616},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1634618639945984}],"mesh":[{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003628","descriptor_name":"Database Management Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btl072","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btl072","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:16510498","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16510498","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.44999998807907104,"id":"https://metadata.un.org/sdg/17","display_name":"Partnerships for the goals"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320310214","display_name":"Fundaci\u00f3n Ram\u00f3n Areces","ror":"https://ror.org/04ra91131"},{"id":"https://openalex.org/F4320323737","display_name":"Ministerio de Ciencia y Tecnolog\u00eda","ror":"https://ror.org/034900433"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1507699035","https://openalex.org/W1971425971","https://openalex.org/W1974748393","https://openalex.org/W1997954369","https://openalex.org/W2006933206","https://openalex.org/W2047693963","https://openalex.org/W2061636126","https://openalex.org/W2065933707","https://openalex.org/W2082833890","https://openalex.org/W2085277871","https://openalex.org/W2103017472","https://openalex.org/W2106391842","https://openalex.org/W2130687290","https://openalex.org/W2130863229","https://openalex.org/W2134672568","https://openalex.org/W2145889895","https://openalex.org/W2147736120","https://openalex.org/W2152653671","https://openalex.org/W2155606054","https://openalex.org/W2159675211","https://openalex.org/W2161062388","https://openalex.org/W2164813401","https://openalex.org/W2166043581","https://openalex.org/W2169356867","https://openalex.org/W4251079740"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"UNLABELLED:":[0],"We":[1],"present":[2],"a":[3,31,52,74],"software":[4],"framework":[5],"and":[6,37,60,68,88],"tool":[7],"called":[8],"Protein":[9],"Interactions":[10],"And":[11],"Network":[12],"Analysis":[13],"(PIANA)":[14],"that":[15,33],"facilitates":[16],"working":[17],"with":[18],"protein":[19,57,66],"interaction":[20,44,58],"networks":[21,59],"by":[22],"(1)":[23],"integrating":[24],"data":[25],"from":[26,95],"multiple":[27],"sources,":[28],"(2)":[29],"providing":[30],"library":[32],"handles":[34],"graph-related":[35],"tasks":[36,62],"(3)":[38],"automating":[39],"the":[40,82],"analysis":[41],"of":[42],"protein-protein":[43],"networks.":[45],"PIANA":[46,79],"can":[47],"also":[48],"be":[49,92],"used":[50],"as":[51,64],"stand-alone":[53],"application":[54],"to":[55,70],"create":[56],"perform":[61],"such":[63],"predicting":[65],"interactions":[67],"helping":[69],"identify":[71],"spots":[72],"in":[73],"2D":[75],"electrophoresis":[76],"gel.":[77],"AVAILABILITY:":[78],"is":[80],"under":[81],"GNU":[83],"GPL.":[84],"Source":[85],"code,":[86],"database":[87],"detailed":[89],"documentation":[90],"may":[91],"freely":[93],"downloaded":[94],"http://sbi.imim.es/piana.":[96]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":6}],"updated_date":"2026-06-23T06:36:01.041984","created_date":"2025-10-10T00:00:00"}